Rates of postpartum depression symptoms increased nationwide during the pandemic, reaching a high of 7.7% in December 2020 to March 2021. States with fewer COVID-19 deaths and lower unemployment rates showed greater increases in symptoms, likely due to reduced access to support systems.
A significant proportion of youth with substance use and depression show early improvements in depression during treatment for substance use. Lower frequency of cannabis use at baseline is a predictor of early depression response. Both additional CBT or community treatment improved depression symptoms in those without an early response.
A new Penn Medicine study suggests that clinically depressed older individuals without other inflammatory conditions do not have elevated levels of inflammation. The study found no significant difference in bloodstream levels of inflammatory markers between depressed and healthy individuals.
Researchers analyzed health records of nearly half a million patients post-heart attack and found that depression was associated with a nearly 50% higher stroke risk compared to those without depression. The study highlights the need for greater attention to mental health in research and practice.
Researchers at University of Michigan found that postpartum depression rose considerably during the pandemic, with 1 in 5 mothers experiencing major depressive symptoms. The study highlights the need for better resources and education on postpartum depression to reduce stigma and improve recovery time.
A new BU study found that individuals with physical, social, and financial assets, particularly higher incomes and fewer savings, were less likely to experience sustained depression during the first year of the pandemic. Persistent depression was highest among people in low-income households and those with fewer savings.
A new study of over 1.1 million new mothers worldwide found that first-time mothers, women under 25, and mothers of twins are at higher risk for postpartum depression. Women aged 40 and older having twins are particularly vulnerable to the condition.
A new study identifies common genetic factors in depression and Alzheimer's disease, suggesting a potential causal role of depression on dementia. The research found that depression played a significant role in AD development, with those experiencing worse depression experiencing faster memory decline.
The Lancet Commission highlights the need for concerted efforts to improve mental health care and prevention globally. Experts stress that depression is a common yet undertreated condition with significant social and economic impacts.
A study by Washington State University found that social support can mitigate the risk of heart disease and death in older American Indians. Higher rates of depression symptoms, poor quality of life, and social isolation were linked to increased mortality, but instrumental social support reversed this effect.
Researchers found gender-specific brain alterations in people with depression, including altered blood-brain barriers in women. They also identified a potential depression biomarker in women's blood samples.
A clinical trial of 18,353 adults found no benefit of omega-3 supplements in preventing depression. The study, led by Massachusetts General Hospital and Brigham and Women's Hospital, tested the effect of daily vitamin D and/or omega-3 supplements on depression risk over a median of 5.3 years.
A new study found that bowel cancer patients are at high risk of clinical levels of depression, with over a third experiencing symptoms up to five years after surgery. The study identified risk factors such as pre-existing depression and anxiety, low social support, and poor health.
A new study found that cognitive behavioral therapy (CBT-I) prevented major depression in older adults with insomnia, decreasing the likelihood of depression by over 50%. CBT-I was more effective than sleep education therapy in preventing depression and promoting sustained remission of insomnia.
Children of depressed parents are more likely to develop depression and poor academic performance, according to a new study published in PLOS ONE. The study found that both maternal and paternal depression have significant effects on children's mental health and educational outcomes.
Longitudinal study reveals cortical thinning in people with bipolar disorder, especially those with more manic episodes. The findings suggest that bipolar disorder may be a neuroprogressive disorder, worsened by the progression of symptoms.
Researchers from Regenstrief Institute found that Patient Reported Outcomes Measurement Information Systems (PROMIS) scales for depression can accurately diagnose and track patient symptoms. The study showed similar accuracy to the widely adopted PHQ-9 scale, supporting PROMIS as a viable screening option.
Researchers found that patients with more severe depression histories showed less brain activity in areas processing emotions, while those who had remitted from depression showed a normal level of activity. This suggests that serious depression may change the way the brain responds to emotion over time, or that people with stronger emo...
A new study has found that worsening depression after diagnosis significantly reduces the survival of lung cancer patients. The trajectory of depressive symptoms was found to be a key factor in understanding how depression relates to premature death. Patients with worsening depression had shorter lifespans, even when receiving advanced...
A study of over 29,000 American women found that breastfeeding significantly reduces the risk of postpartum depression. Women who breastfed for longer periods had lower rates of postpartum depression, with those breastfeeding for 6-12 months showing the greatest reduction.
Problem-solving therapy led to short-term changes in the amygdala, a key region for emotion regulation, in individuals with comorbid depression and obesity. The study suggests that neural target changes at two months predicted improved behavioral outcomes after 12 months.
Research by the University of Bristol found that children born to depressed mothers are more likely to develop depressive symptoms by age 24, with scores almost three points higher than offspring of non-depressed mothers. The study highlights the importance of antenatal and postnatal depression support.
Patients with bipolar disorder experiencing manic episodes show abnormal brain changes, including faster cortical thinning, compared to those without episodes. The study also found associations between brain ventricle enlargement and accelerated cognitive decline in bipolar patients.
A new study found that psychological interventions can have a significant effect on the treatment of subthreshold depression in adolescents. The meta-analysis showed that approximately eight adolescents need to be treated to see one more positive outcome than no treatment, with moderate effects size.
A new study published in Neurology shows that people with multiple sclerosis (MS) and depression are more likely to die over the next decade than those with MS alone or neither condition. The study also found a higher risk of developing vascular disease, such as heart attack and stroke, among individuals with both MS and depression.
Researchers have found that improved learning processes are associated with reduced symptoms of depression. By using brain imaging and mathematical modeling, the team identified distinct paths to depression symptoms and proposed a new approach for treating clinical depression.
A University of Otago study found that women with postpartum depression experience different intensity and hedonic perception of smells compared to healthy women. The research adds evidence to the argument that postpartum depression should be studied separately from major depression.
A new study published in The Lancet Psychiatry suggests that electroconvulsive therapy (ECT) is a medically safe mental health intervention for individuals with severe depression. The research, which analyzed over 10,000 patients, found no clinically significant increased risk of serious medical events with ECT exposure.
A large study found that depression symptoms in fathers of premature infants persist after discharge from the NICU, affecting their ability to engage in positive parenting activities. The researchers emphasize the need for increased attention to mental health support for new fathers during this critical period.
A phase 2 trial found that a single one-hour treatment with nitrous oxide can relieve symptoms of treatment-resistant depression for several weeks. The study showed significant improvements in depression symptoms, with a four-fold lower risk of adverse effects at lower concentrations.
A large-scale genetic analysis of depression identified 178 loci and 223 single-nucleotide polymorphisms associated with increased depression risk. The study, involving over 1.2 million participants, provides new insights into the biological basis of depression and potential drug repurposing.
A study published in BJPsych Open found that women with depression during pregnancy or a history of depression had reduced quality of mother-infant interactions. Despite this, all mothers and their babies improved over time, indicating potential for future attunement.
After cognitive behavioral therapy, serotonin transporter levels increased in individuals recovering from depression. This finding suggests that the serotonin system may play a role in protecting against depression, rather than causing it.
Patients with glandular fever who have hospital contact are at a greater risk of developing depression, according to the largest study yet. The study found a 40% relative risk increase in depression after hospitalization for glandular fever, particularly among young people.
Researchers have identified 19 genes and 25 corresponding proteins that may contribute to the cause of depression. These findings offer promise as potential targets for new depression treatments and could serve as biomarkers for depressive symptoms.
IU School of Medicine researchers have developed a blood test that can distinguish between severe depression and bipolar disorder, as well as predict future episodes. The test uses RNA biomarkers to inform tailored medication choices, offering a promising precision medicine approach to treatment.
A small study found that exposure to phthalates and bisphenols, commonly found in plastics, may contribute to lower progesterone levels during pregnancy and an increased likelihood of developing postpartum depression. Reducing exposure to these chemicals could be a potential avenue for preventing postpartum depression.
Research suggests non-drug therapies like exercise and social interactions may reduce symptoms of depression in people with dementia. These interventions are found to be as or more effective than drugs in treating depression, suggesting a shift towards 'social' prescribing.
Research highlights increased depression risk after stroke compared to heart attacks, with female stroke patients facing a higher risk. Studies found that post-stroke depression affects up to a third of stroke patients and has poorer quality of life outcomes.
Researchers have identified ezogabine, a drug that opens potassium channels in the brain, as a promising new approach to treating depression. The study showed significant improvements in depressive symptoms and anhedonia in patients with depression.
A new study found that people with depression and anxiety may experience dementia symptoms about two years earlier than those without these conditions. Those with bipolar disorder or schizophrenia may start experiencing symptoms three to seven years earlier.
A new study led by the University of Ottawa found that chronic sleep disruption during adolescence can lead to depression in both males and females. Adolescent females were particularly vulnerable to stress hormone release and activation of stress-sensitive brain cells, suggesting a higher risk of mood disorder development.
A large long-term study found that women with PTSD and depression have an almost fourfold greater risk of early death from various causes than women without trauma exposure or depression. The study suggests that other factors, such as stress hormones, may account for the higher risk.
A recent analysis found limited research evaluating depression screening tools in patients with kidney failure. The most extensively studied tool was the Beck Depression Inventory II (BDI-II), but many studies were small and had shortcomings.
A longitudinal study of almost 85,000 people found that a combination of lifestyle interventions including optimal sleep and reduced screen time can help prevent depression. Additionally, healthy dietary patterns and physical activity were also associated with lower rates of depressed mood.
Researchers at Albert Einstein College of Medicine and Montefiore Health System are searching for biomarkers to predict the duration and severity of depression in adolescents. The goal is to identify teens who need more significant help with their depression, potentially leading to new treatments.
A new study published in The Lancet Psychiatry found that loneliness is a leading cause of depression in older adults, with nearly one in five cases potentially preventable. The research, led by UCL researchers, suggests that subjective experiences of loneliness contribute to depression up to 12 years later.
Researchers found that abnormal amyloid deposits were present in fewer older adults with major depression compared to non-depressed control subjects. However, the study suggests that depression is still a risk factor for cognitive decline, but through a mechanism other than amyloid deposition.
Tropical Depression 22 is strengthening in the Gulf of Mexico, with NASA-NOAA's Suomi NPP satellite providing infrared images. The depression is forecast to move slowly and could strengthen into a hurricane by Sunday.
A new study found that depression is associated with increased inflammation and metabolic changes, but not anxiety. The research used blood samples from over 300 people with depression and anxiety to identify biochemical markers, revealing distinct patterns of lipid metabolism and immune system involvement.
A new study from Binghamton University found that children with social anxiety are more likely to develop depression, especially those whose mothers have a history of depression. The researchers suggest that the combination of these risk factors may be particularly insidious.
A new study from Boston University School of Public Health found that 27.8% of US adults experienced depression symptoms in mid-April, compared to 8.5% before the pandemic. Income and savings were the most significant predictors of depression symptoms during COVID-19.
Tropical Depression 15 formed over the Atlantic Ocean, east of North Carolina, and has been battling wind shear. The depression is currently 140 miles east-southeast of Cape Hatteras, moving toward the east-northeast at 14 mph.
A Danish study found that none of the most common high blood pressure medications increase depression risk, while nine lowered it. The medications enalapril and ramipril, amlodipine and other calcium antagonists, and beta-blockers like propranolol lowered depression risk.
Researchers found that depression is an intrinsic part of early phase psychotic disorders and suggest targeting depression as a key factor in treatment. The study suggests antidepressants alongside anti-psychotic drugs could be an effective additional first-line treatment for psychosis.
Researchers from Massachusetts General Hospital identified social connection and reducing sedentary activities like TV watching as valuable targets for preventing depression. The study found that frequency of confiding in others, visits with family and friends, were strong protective factors against depression risk.
New research found prenatal depression alters child's brain connectivity, with weaker white matter connections linked to increased aggression and hyperactivity in male children. The study suggests a need for better prenatal care to recognize and treat prenatal depression.
A new study published in JAMA Network Open found that maternal depression during and after pregnancy significantly increases the odds of depression in offspring during adolescence and adulthood. The research, which examined over 15,000 children, shows that perinatal depression can have a lasting negative impact on mental health.
Researchers have found genes related to inflammation and stress that may help tailor treatments for depression. These findings support the idea that patients with treatment-resistant depression have heightened inflammation compared to those who respond to medication.
A meta-analysis of 62 studies and 44,000 participants reveals that eight specific types of early life stress are associated with an increased risk of developing depression in youth. These include emotional abuse, poverty, and death of a family member, while others like sexual abuse and physical abuse show stronger links to the condition.