A national Taiwanese health database study found people with bipolar disorder were nearly seven times as likely to develop Parkinson's disease as those without the condition. The risk was higher for those hospitalized more frequently, developing the disease at a younger age.
A two-year project aims to explore the link between the human microbiome and autism spectrum disorder, a developmental disorder affecting communication and behavior. The study, funded by a $1.94 million grant, will analyze key metabolites produced by microbes in patients with central nervous system disorders.
A new study using single-cell analysis of brain cells from autism patients found that specific genetic changes in neural cells and brain circuits correlate with the clinical severity of autism. The research identified autism-specific genes that could represent high-priority targets for new therapeutic treatments.
A study found that 623,000 US parents with opioid use disorder live with children under 18, with few receiving treatment. Meanwhile, healthcare accounts for between 5-15% of premature death variation, with behavioral factors driving more mortality variation.
An estimated 623,000 US parents with opioid use disorder are living with children under 18, with fewer than one-third receiving treatment. Additionally, four million parents have other substance use disorders with low treatment rates.
Researchers identified 20 new genetic associations with bipolar disorder in a massive study of over 50,000 subjects across 14 countries. The findings highlight the complexity of the disease and its overlap with other psychiatric disorders.
A study found prolonged exposure therapy to be more effective in reducing PTSD symptoms and heavy drinking in veterans with both conditions. The treatment also led to higher rates of PTSD remission compared to a coping skills therapy approach.
Researchers have found distinctive differences in white matter pathways among young people with conduct disorder, linked to callous behavior and reduced empathy. The study may help clinicians diagnose the condition more accurately and guide effective interventions.
A major study by the Ontario Child Health Study found that one in five Ontario children and youth suffer from a mental disorder, with a significant increase in anxiety and depression. The study also revealed that many children have contact with other health providers and settings, often through schools.
A new study published in Addiction found that medication treatment for opioid use disorder significantly reduces the risk of arrest and incarceration. The research, led by UMass Amherst public health scientist Elizabeth Evans, used data from a large randomized clinical trial to compare the effects of two medications on social outcomes.
Abnormal brain network interactions found in adults with major depressive disorder, associated with childhood trauma and current symptoms of depression. Traumatic experiences alter connectivity in multiple resting-state networks, including those involved in attention and sensory processing.
The study analyzed 26 widely-used protein disorder prediction methods and found that they vary noticeably in performance. This thorough comparison provides valuable insights for protein scientists to make informed choices about which programs to use.
A study published in the Journal of Neurology, Neurosurgery and Psychiatry found increased connectivity between motor regions and the multimodal integration network in patients with FND. Symptom severity also correlated with increased coupling between the insula and the amygdala, which improved response to treatment.
Research found social anxiety disorder had strongest association with alcoholism and predicted it over other anxiety disorders. Individuals with social anxiety were at higher risk of developing later alcoholism compared to those with other anxiety disorders.
A large multi-centre study of over 1,200 patients with REM sleep behaviour disorder found a high risk of Parkinson's disease progression and identified several strong predictors, including motor difficulties and mild cognitive impairment. The study's findings will improve clinical trial selection and therapy development.
A new method uses AI to screen for fetal alcohol spectrum disorder (FASD) by analyzing eye movements, providing an affordable and efficient way to detect the condition. The tool has the potential to reach millions of children worldwide who may be at risk, reducing secondary cognitive and behavioral disabilities.
Researchers discovered a precise pathway causing neurodevelopmental disorders, including rare condition Kaufman oculocerebrofacial syndrome. Genetic sequencing revealed the buildup of protein BCKDK in the brain, leading to intellectual disability and speech loss.
A new NIH-funded study identifies the common occurrence of mental health symptoms after mild traumatic brain injury (mTBI) in civilians. Lower education levels, African-American status, and history of mental illness are associated with increased risk of post-traumatic stress disorder (PTSD) and major depressive disorder.
A genome-wide study found that copy number variants (CNVs) are more closely associated with a 'schizophrenia-like' bipolar disorder subtype than the broader form of bipolar disorder. This suggests a distinct mechanism underlying the biology of schizoaffective disorder, which shares symptoms with schizophrenia.
Reactive attachment disorder is a social functioning disorder characterized by ambivalence towards comfort and emotional withdrawal. A study of 614 children with RAD found that parents' psychiatric diagnoses increased the child's risk by nine-fold for mothers and six-fold for fathers.
The study analyzed register data from 5.9 million people in Denmark, uncovering how different types of mental disorders accumulate across a lifespan. Comorbidity is confirmed as the rule, not the exception, with those diagnosed with one mental disorder more likely to receive diagnoses for all other types.
A recent study of 5.9 million individuals found that the risk of developing a second mental health disorder is increased, even 15 years after an initial diagnosis. Younger people are significantly more at risk of developing multiple mental health disorders over time.
A new study from Johns Hopkins Bloomberg School of Public Health found that only 36.1% of US outpatient treatment centers offer medication treatment for opioid use disorder, with significant variation among states. Treatment facilities in Medicaid expansion states were more likely to offer medication treatment.
Researchers discovered that people with bipolar disorder have lower levels of the CPG2 protein, which regulates glutamate receptor numbers at excitatory synapses. Genetic variations in the SYNE1 gene, encoding the protein, undermine its expression and function in neurons.
Among American Indians and Alaska Natives, 41% have lifetime alcohol use disorder; 34% seek alcohol-related treatment. Men aged 35-64 are most likely to receive treatment, with 20.5% of non-Hispanic Whites also seeking help.
A systematic review of the Yale Food Addiction Scale reveals that clinical and non-clinical samples with higher body mass and incidence of eating disorders exhibit higher scores of YFAS. The studies also suggest that food addictions differ according to population studied and sample selection methods.
A study found that people taking antidepressants, having post-traumatic stress disorder or anxiety are at risk of developing REM sleep behavior disorder. Men are also more likely to have the condition. Lifestyle factors such as education level, income, smoking status and moderate to heavy drinking habits were also linked to the disorder.
A study by Society for Consumer Psychology found that hiding information about consumption choices increases sense of connection. Researchers conducted experiments where participants were asked to keep their brand choices secret, revealing that secrecy intensified self-brand connections and increased loyalty.
A recent study found that food insecurity is associated with an increased likelihood of binge-eating disorder and obesity in US adults. Individuals with binge-eating disorder and obesity reported cutting meal sizes and skipping meals more frequently than those with a healthy weight.
A new study by Virginia Commonwealth University and Lund University in Sweden found that children of parents with alcohol use disorder are more likely to get married at younger ages and less likely to marry at older ages. They are also more likely to marry a person who has alcohol use disorder themselves.
A new study led by an Iowa State University researcher found that higher average potency cannabis at first use increases the risk for the first symptom of cannabis use disorder within a year. Individuals who started using cannabis with 4.9% THC had 1.88 times higher risk, while those with 12.3% THC had 4.85 times higher risk.
Later-born siblings of children with autism spectrum disorder (ASD) or attention-deficit/hyperactivity disorder (ADHD) are at higher risk of developing the same disorder. The study analyzed data from over 15,000 siblings and found that those born after an older child with ASD or ADHD were more likely to be diagnosed with either condition.
Despite unmet need for treatment of substance use disorders, telemedicine use for this condition remains woefully underused. The study found that telehealth visits for substance use disorder accounted for only 1.4 percent of all telehealth visits, highlighting a significant gap in access to care.
A new specialist programme at South London and Maudsley NHS Foundation Trust has been shown to significantly reduce hospital readmissions for people with bipolar disorder. The OPTIMA Mood Disorders Service provides intensive, specialist treatment tailored to individual needs, resulting in lower rates of re-admission.
A study of 4,500 US children aged 9-10 found an overall frequency of eating disorder diagnoses at 1.4%, with no significant differences between girls and boys. The prevalence of specific disorders varied, including anorexia nervosa (0.1%), binge-eating disorder (0.6%), and other specified feeding and eating disorders (0.7%).
A study by Penn State researchers found that there are five distinct classes of people with alcohol use disorder, each characterized by specific symptoms. Young adults were more likely to fit the profile with excessive drinking and withdrawal symptoms, while older adults struggled with cutting back on their drinking.
A novel multisystem disorder has been identified due to bi-allelic variants in the CCDC47 gene, affecting individuals with symptoms such as woolly hair, liver dysfunction, and global developmental delay. The study demonstrates the importance of CCDC47 in normal development and highlights the need for further research into this condition.
New reviews on symptom stability over time for bipolar disorder and psychotic disorders highlight the importance of diagnostic accuracy for prognosis and treatment. Diagnostic instability is associated with factors such as extreme age, female sex, and substance abuse, emphasizing the need for enhanced tools to quantify risk.
Researchers found that reducing overall alcohol consumption can lead to fewer people developing an alcohol disorder. The study also showed that men are at greater risk of developing a disorder and are less likely to quit.
A recent study estimates that over 275,000 people in Massachusetts have opioid use disorder, with the prevalence increasing from 2.7% in 2011 to 4.6% in 2015. The study used linked public health data sets to provide a more accurate picture of the impact of opioids in the state.
Experimental physicists at the University of Illinois have created a new disorder-induced topological state, previously predicted to occur in electronic materials. The topological Anderson insulator phase was first discovered theoretically in 2009 and its origin was further explained in subsequent works.
A pilot study found that pregnant women with a history of depression or bipolar disorder process infant facial and vocal signals of emotion differently. Pregnant women with bipolar disorder had difficulty recognizing all facial expressions, while those with previous depression showed a negative bias in adult facial expression recogniti...
A clinical trial suggests that individuals with bipolar disorder who have a high-quality diet, low BMI, or anti-inflammatory properties may respond better to nutraceutical treatment. The study found statistically significant results but emphasizes the need for replication in larger trials before firm conclusions can be drawn.
Researchers identified a rare genetic disorder in a human patient caused by mutations in the ornithine decarboxylase 1 (ODC1) gene. The disorder is characterized by large birth weight, hair loss, and developmental delays, and may be treatable with the FDA-approved drug DFMO.
A study by the American Psychological Association found that 35% of students from 19 colleges in eight countries reported symptoms consistent with at least one mental health disorder. Major depressive disorder was the most common, followed by generalized anxiety disorder.
A study in Japanese patients found that common genetic variations, including copy number variations (CNVs), underlie both autism spectrum disorder and schizophrenia. The researchers identified 12 CNV loci associated with these disorders and observed an overlap of pathogenic CNVs between the two conditions.
A recent study by Boston Medical Center found that only 24% of youths receive FDA-approved medications for opioid use disorder within three months of diagnosis. Patients who receive medication are more likely to remain in treatment compared to those who only receive behavioral health services.
Researchers found that brain activity in the amygdala responds differently to facial expressions in individuals with bipolar disorder versus those with depression. The study demonstrated 80% accuracy in distinguishing between the two conditions. This finding holds promise for improving diagnosis and treatment of these disorders.
Research using brain scans found that neurons in the amygdala respond differently in people with bipolar disorder versus those with depression. The study showed an 80% accuracy rate in distinguishing between the two conditions. This discovery could lead to more accurate diagnoses and better treatment outcomes for patients.
A novel saliva-based panel is being developed to aid clinicians in the early diagnosis of autism spectrum disorder based on changes in oral microbial communities. The study found altered microbial gene expression patterns associated with energy processing and lysine degradation, indicating potential biomarkers for ASD.
Researchers discovered CPEB4, a molecule regulating protein synthesis, is impaired in most autism cases. The study found defects in CPEB4 lead to dysregulation of hundreds of genes associated with autism.
A prospective study of over 3700 US juveniles found an independent association between conduct disorder and mortality hazard. Conduct disorder was linked to a 4.99 times higher risk of mortality compared to community controls.
A Massachusetts-based study found that opioid overdose events decreased during pregnancy but increased in the postpartum period, particularly when fewer resources were available to mothers with substance use disorder. The research team developed a unique dataset linking statewide resources and found that women with opioid use disorder ...
Researchers at Joslin Diabetes Center found that gut microbes contribute to signs of negative feelings and brain chemistry in obese mice. Antibiotics reversed these behaviors, demonstrating a significant link between the microbiome and mental health outcomes.
A position paper from the American Academy of Sleep Medicine recommends image rehearsal therapy as a useful treatment option for nightmare disorder and PTSD-associated nightmares. Cognitive behavioral therapy, hypnosis, and other interventions may also be effective, while clonazepam and venlafaxine are not recommended.
Researchers at RIKEN Center for Brain Science found mitochondrial dysfunction affects serotonergic neurons in mice with ANT1 mutations, linking the two pathways.
Research suggests that females with borderline personality disorder experience worsening symptoms during the perimenstrual window of their menstrual cycle. Symptoms such as depression and anxiety increase by at least 30 percent during this time, which is particularly concerning for individuals at high risk of suicide.
A new study found that a family history of psychiatric disorders, especially bipolar disorder, increases the risk of postpartum psychiatric conditions in mothers. The risk is higher when there's a male relative with a psychiatric disorder, and it's more pronounced among women without prior mental health issues.
Research reveals that young people with Conduct Disorder show lower amygdala responses to angry and sad faces, suggesting a possible link to emotion regulation difficulties. The study also found normal connectivity between the amygdala and prefrontal cortex in those with psychopathic traits.
A study by the Hebrew University of Jerusalem found a link between prolonged acetaminophen use during pregnancy and an increased risk of attention deficit hyperactivity disorder (ADHD) and autistic spectrum disorder (ASD). The analysis shows a 30% increase in relative risk for ADHD and a 20% increase in relative risk for ASD.