Articles tagged with Human Reproduction
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The lack of widely accepted standards for managing reproductive health risks in space is a pressing concern. Limited reliable data from human studies shows that space can be hostile to human biology, with conditions like altered gravity, cosmic radiation, and circadian disruption affecting reproductive processes.
A new American Heart Association scientific statement highlights the importance of aggressive blood pressure control, early recognition of stroke symptoms, and prompt treatment for pregnant and postpartum women. Controlling blood pressure before and after delivery can help save lives and improve outcomes for mothers and their babies.
A study by UC Riverside scientists reveals that the cysts of Toxoplasma gondii contain multiple distinct subtypes of parasites, each with different biological roles. This discovery offers new insights into how the parasite causes disease and why it has been difficult to treat.
Alcohol screening increased from 61% to 81%, and intervention among positive screens rose from 22% to 67%. Practices improved documentation of pregnancy intention, using the AUDIT-C tool more frequently. This approach empowers local staff to lead care improvement efforts.
A new review of over 100 clinical trials found that 13 common labor induction methods are similarly effective, with low-dose vaginal misoprostol being the most commonly used and safest. However, some methods showed better success rates for specific outcomes, such as oxytocin with amniotomy for achieving vaginal birth within 24 hours.
A Johns Hopkins University-led team analyzed genetic data from nearly 140,000 IVF embryos and found robust connections between specific variations in a mother's DNA and her risk of miscarriage. The study identified key genes that govern chromosome pairing and cohesion, shedding new light on human reproduction.
A new study published in Environmental Science & Technology found that exposure to wildfire smoke during the third trimester may raise the risk of autism diagnoses in children. Mothers who were exposed to more than 10 days of wildfire smoke had a 23% higher risk of their child being diagnosed with autism by age 5.
A new study found pregnant individuals with IBD have higher levels of pro-inflammatory cytokines in their vaginal mucosa than healthy controls. However, a higher intake of vegetables and lower added sugars was associated with lower inflammation and increased beneficial microbe Lactobacillus crispatus.
A study by Oregon Health & Science University found that states with abortion restrictions have worse maternal health outcomes for patients using fertility treatment. The research analyzed over 400,000 births conceived through fertility treatments and found a statistically significant increase in serious maternal health complications.
The study found that women with two to three children tend to live the longest, while those with an above-average number of children have shorter lifespan. Pregnancies between ages 24 and 38 were also linked to more favorable aging patterns.
A new study found that only a quarter of reproductive health experts prescribe self-administered injectable contraceptives, despite its safety and effectiveness. The study identified barriers such as concerns about patient ability, medication availability, and lack of standardized counseling approaches.
Researchers found that over half of IVF cycles in the US were performed at clinics affiliated with private equity firms, sparking concerns about the impact on quality and accessibility. The study's authors emphasize the need for further research to understand the benefits and risks of this business model.
A new study found that a sizable minority of people with migraine with aura still receive estrogen-containing birth control pills and hormone therapy, despite treatment contraindications. The study highlights the need for updated research on stroke risks associated with these medications among people with this type of migraine.
Researchers found that Asian and Singaporean women with PCOS have better reproductive outcomes, including higher pregnancy rates and oocyte retrieval per cycle, compared to women without PCOS. Women with PCOS tend to maintain a higher ovarian reserve as they age, allowing for more robust responses to fertility treatment.
A study of 349 new parents found intrusive thoughts and psychotic-like experiences more prevalent than thought, causing severe distress linked to higher parenting stress and lower satisfaction. The research highlights the need for normalisation, stigma reduction, and targeted support for affected parents.
A new study suggests that genetic differences passed down from ancient human ancestors and exposure to common chemicals could explain why some women are more likely to develop endometriosis. Researchers identified six genetic variants linked to the condition, which also occur in genes sensitive to modern pollutants.
A Cochrane review found no significant effect of calcium supplementation on pre-eclampsia, contradicting long-held assumptions. The review excluded small and unreliable studies that previously suggested benefits of calcium supplementation.
Researchers have found a correlation between exposure to widely used pesticides and lower sperm quality in male rodents. The review of 21 studies indicates that neonicotinoid pesticides may disrupt hormones and damage testicular tissue, leading to potential harm to human reproductive health.
Two new Cochrane reviews show that HPV vaccines are effective in preventing cervical cancer and pre-cancerous changes, especially when given to young people before they are exposed to the virus. Girls vaccinated before the age of 16 were found to be 80% less likely to develop cervical cancer.
A recent study found distinct changes in NAD-related metabolites in women with recurrent miscarriage, suggesting a deeper metabolic imbalance. The findings may lead to the identification of potential biomarkers for risk assessment and new avenues for treatment.
A study by Aston University academics found that while access to antiseizure medication is expanding globally, it's not always prescribed safely. Valproate, widely used, poses significant risks during pregnancy, including birth defects and neurodevelopmental problems.
Researchers found that Finnish mothers who had more children during periods of famine lived shorter lives, with each child shortening their mother's lifespan by half a year. The study suggests that reproductive effort can affect human aging under harsh conditions.
A new study found that the Dobbs v. Jackson Women's Health Organization decision led to a significant increase in tubal ligations, a surgical procedure that permanently prevents pregnancy, with 51% more procedures performed across four medical centers between 2021 and 2023.
A nationally representative survey found that frequent parent-teen communication is associated with increased teen self-efficacy for sexual and reproductive health information. Teens whose parents feel comfortable discussing topics are more likely to seek services, highlighting the importance of accurate information and open dialogue.
A review of 21 experimental studies suggests that exposure to neonicotinoid pesticides can lower sperm quality and disrupt hormones in males. The studies found that these insecticides, commonly used in farming, can be absorbed into soil, water, and plants, leading to potential harm to human reproductive health.
Children born to mothers infected with COVID-19 while pregnant are at a higher risk of developing developmental delays, including speech difficulties and autism. The study found that males were more susceptible to adverse outcomes compared to females.
Researchers found that baseline Anti-Mullerian Hormone (AMH) levels between 2.1-2.8 ng/ml correspond to 35-42% of live birth rates in women with cancer using fertility preservation. The study aims to improve prediction and standardization for fertility treatments.
A study published in the journal Bone found a clear link between osteomalacia and a fivefold increased risk of emergency caesarean sections or vacuum-assisted delivery. Vitamin D deficiency is a key underlying cause of osteomalacia, which may influence labor outcomes and increase the need for urgent obstetric interventions.
The European Society of Endocrinology has published a new Clinical Practice Guideline for the Management and Evaluation of Menopause and the Perimenopause. The guideline provides guidance on evaluating and managing women with menopause-related symptoms, including hormone therapy benefits and risks. It also discusses alternative treatme...
A £2 million Wellcome Discovery Award will fund a five-year project to study the molecular interaction between Plasmodium falciparum and the placenta. The research aims to catalogue disrupted molecular and cellular pathways that could be targeted for intervention, contributing to the development of diagnostics and vaccines.
A Kinsey Institute study found that gaps in sex education can have lasting impacts on adult relationships, including relationship struggles, lack of confidence, and reduced quality of life. Most participants learned only a few topics in school, with many lacking information on healthy relationships, consent, and communication.
Research reveals that ovarian aging is not just about egg quality, but also the surrounding cells and tissues. The study found that eggs cluster in pockets surrounded by egg-free zones, which decline in density with age, influencing egg lifespan and maturation.
Research reveals that Bifidobacterium breve in pregnant mothers regulates the placenta's hormone production, reducing complications and improving fetal growth. The study opens up a new approach to assessing pregnancy health through gut microbiome analysis.
Researchers discovered that sperm mark centromeres with less CENPA, leading to unequal strength between maternal and paternal chromosomes. To compensate, a second protein, CENPC, recruits extra CENPA to the father's chromosomes, equalizing centromeric strength before cell division.
A UCLA study reveals that morning sickness symptoms are part of a natural inflammatory response to biological changes during pregnancy. Women's immune systems produce cytokines to protect both mother and fetus from infection while avoiding harmful substances.
A landmark study reveals that a specific event guides the accurate distribution of chromosomes in egg and sperm cells, ensuring unique gene combinations. The research sheds light on fertility issues and potential treatments, with implications for human reproduction.
The global impact of IVF continues to grow, with estimated 20 million IVF births worldwide, increasing the demographic importance of fertility needs. IVF has become a more effective route to parenthood for those previously unable to conceive.
A poet's extensive rewrites in Dannie Abse's 1980 autobiography 'A Matter of Life' gave the narrative an emotional storytelling tone, highlighting the human stakes of IVF. The book's commercial success helped promote IVF at a time when the technique was controversial.
A study found that ultrasound-guided IUD insertion is faster than conventional methods, reducing procedure time by an average of seconds. Despite this, pain levels were not significantly different between the two groups.
Research from Texas McCombs reveals that trust-based messages delivered by credible sources increase the likelihood of women seeking life-saving exams. Peer-empowering messages led to the largest increase in adoption, challenging traditional strategies of relying on infographics or factual information.
A large international clinical trial found that elinzanetant significantly reduces hot flashes and night sweats in postmenopausal women by over 73%. The drug also shows secondary benefits such as improved quality of life and reduced sleep disturbances, with no harmful effects on the liver or bone density.
Dr. Alex Tsompanidis proposes placental hormone production shaped human cognitive capabilities, redefining autism origins and neurodiversity. His research could lead to screening protocols and support for children with developmental differences.
Boston University has been awarded a prestigious $4.5 million grant from the National Institutes of Health to further women's health research. The five-year award will support early-career faculty members through a two-year program, focusing on addiction science, maternal and child health, and sex influences on health outcomes.
Scientists have achieved a major breakthrough by 3D bioprinting miniature placentas, which can accurately replicate the human placenta. This technology has the potential to transform pregnancy research by allowing for the study of serious complications like preeclampsia.
Researchers from The University of Osaka identify CFAP91 and EFCAB5 as crucial proteins for sperm motility. Loss of function in either protein reduces male fertility in mice. Understanding these proteins' functions may help diagnose infertility and develop new treatments.
Researchers identified genes associated with breastfeeding disorders and postpartum breast cancer in the mammary gland, revealing potential new targets for investigation. The study provides a detailed atlas of genetic expression for the adult developmental cycle of the mammary gland.
A team of Cornell University researchers has developed a groundbreaking device that automates oocyte cumulus removal, reducing manual labor and preserving embryo development outcomes. The vibration-powered chip ensures consistent results, minimizes contamination risks, and is portable and cost-effective.
A survey of Australian women with hyperemesis gravidarum found half considering termination and 9 in 10 having fewer children. Only half rated popular treatments as effective.
Researchers developed a technique to study embryonic implantation in mice by keeping mouse uterine tissue alive outside the body. The method showed over 90% efficacy for implantation and provided insights into the maternal-embryonic signaling process.
A new Rice University study finds hormonal contraceptives shape how women experience emotions in the moment and remember emotional events later. Women on hormonal contraceptives showed stronger emotional reactions and remembered fewer details of negative events when using emotion regulation strategies.
Researchers at Rice University developed a mathematical model that sheds light on ovarian aging and menopause timing. The study reveals synchronized and predictable patterns of follicle depletion, accelerating during midlife, which helps explain why menopause typically occurs at similar ages for most women.
A human study found that ultra-processed diets lead to increased weight gain, disrupt hormone levels, and introduce pollutants affecting sperm quality. Men on an ultra-processed diet gained more fat mass and had lower testosterone and follicle-stimulating hormone levels compared to those on a minimally processed diet.
Researchers at Lehigh University and the Cleveland Clinic are developing a nonsurgical therapy for pelvic organ prolapse using drug-delivering nanoparticles. The treatment aims to delay or reverse matrix degradation, reducing the severity of POP in patients with earlier stages of the disorder.
A new study in the American Journal of Preventive Medicine found that two-thirds of women of reproductive age in the US have at least one modifiable risk factor for birth defects. The analysis highlights the need for improved preconception health and identifying and addressing these changeable risk factors before pregnancy.
A recent study developed a highly accurate risk prediction framework for preterm birth using genomics, transcriptomics, and large language models. The model achieved an AUC of nearly 90%, making it the most powerful approach in predicting preterm birth.
Researchers found a strong correlation between industrial pollution exposure during pregnancy and the risk of intellectual disabilities in grandchildren. A study using Utah Population Database data revealed that grandmothers' prenatal exposures can increase the risk of intellectual disabilities in their grandchildren's children.
Girls who go through puberty before age 11 have double the risk of type 2 diabetes, heart failure, and obesity, while women who give birth before 21 have quadruple the risk. Later puberty and childbirth are associated with longer lifespan, lower frailty, and reduced disease risk.
A new study found that probiotics significantly reduced the presence of antibiotic-resistant bacteria and multidrug-resistant bacteria in the infant gut, while also promoting a more typical gut microbiome. This breakthrough has major implications for the global AMR crisis, particularly for preterm infants.
Human embryos exert significant forces during implantation to break down surrounding tissue and penetrate the uterus. The study reveals that effective invasion is associated with optimal matrix displacement, highlighting the importance of these forces in the implantation process.
A study analyzed 100 TikTok videos on contraceptive health, finding that over half rejected hormonal birth control and a third expressed distrust in health professionals. Fertility awareness and cycle tracking were the most frequently discussed subjects, often without disclosing limitations or promoting ineffective methods.