Articles tagged with Cancer Risk
Researchers analyzed US cancer registration systems and found disparities in racial minorities' representation, despite revisions to the established standards. The study revealed significantly lower rates for American Indian or Alaskan Native populations under the 1997 standards compared to the previous 1977 standards.
Researchers have identified a hidden molecular mechanism involving two proteins that allows tumors to resist treatment. A new gelatin-based nanoparticle has been developed to shut down both proteins simultaneously, showing promising results in early studies with mice.
A study published in The International Journal of Cancer found that children born by planned C-section have a higher risk of developing acute lymphoblastic leukaemia (ALL) later in life. The risk was 21% higher in children born by planned C-section compared to those born vaginally.
A whole-genome sequencing study found fine-particulate air pollution to cause more cancer-related changes than secondhand smoke. Researchers analyzed lung tumors from 871 never-smoker patients across 28 geographic locations worldwide and linked air pollution exposure to increased genomic changes.
A new study by the NIH found that hormone therapy may alter breast cancer risk in women under 55. Women treated with unopposed estrogen hormone therapy were less likely to develop breast cancer, while those using estrogen plus progestin hormone therapy were more likely to develop the disease.
A cohort study found a strong association between cancer incidence rates and both environmental burden and racial composition. The findings suggest the need for targeted community interventions in areas with high environmental burden and minority populations.
Researchers found that it took 13 years for cervical cancer screenings to halve among women over 65, and even longer for prostate cancer screenings to decrease significantly. The study emphasizes the need for more effective tracking mechanisms to identify and reduce inappropriate screening practices.
A new study found a sharp increase in appendix cancer incidence rates for those born after 1945, particularly among Generation X and Millennials. The researchers estimated age-specific incidence rates of appendiceal adenocarcinoma per 100,000 persons between 1975 and 2019.
A revolutionary AI model has been developed to diagnose lung cancer without relying on costly GPU servers or massive datasets. The ultra-lightweight model achieved a discrimination performance corresponding to an AUC value of 0.92, outperforming state-of-the-art large-scale AI systems.
The ESMO Gynaecological Cancers Congress 2025 will convene in Vienna, Austria, from June 19-21, featuring novel data on immunotherapy combinations and emerging treatment strategies for rare gynaecological cancers. The congress will also explore innovative approaches using antibody-drug conjugates.
Researchers have identified FAM111B as a promising candidate for glioma treatment. The study found that FAM111B overexpression enhances glioma malignancy through the PI3K/AKT pathway, providing a novel avenue for therapeutic intervention.
Researchers identified C5aR1 as a novel prognostic biomarker and potential therapeutic target for treating metastatic skin cancer. Elevated C5aR1 presence suggests increased metastasis risk and poor survival in patients with cutaneous squamous cell carcinoma.
A study found that rising temperatures in the Middle East and North Africa are associated with higher rates of these cancers. The prevalence of the different cancers rose by 173 to 280 cases per 100,000 people for every additional degree Celsius.
A large-scale study published in eClinicalMedicine found that transmasculine and gender-diverse individuals who use testosterone for an average of five years do not have an increased risk of gynecological cancer. The research, which followed 1955 participants, suggests that hormone therapy may be safe for this group.
The NCCN Policy Summit brought together experts to discuss ways to strengthen collaborative cancer care, from early detection to survivorship. Key findings include the need for better communication and coordination between primary care and oncology providers.
A study published in The Lancet Regional Health – Europe found that patients with low household income were more likely to be diagnosed late and receive less effective treatment for liver cancer. This highlights the need for targeted screening in deprived areas to improve early diagnosis and survival rates.
Pennington Biomedical welcomes Dr. Adithya Hari, MD, with expertise in nuclear oncology and translational science, strengthening cancer research and patient-centered innovation in Louisiana. He will establish a research program focused on nuclear medicine and dedicate time to direct patient care through a clinical partnership.
A new review advocates for building confidence in AI applications by implementing robust data governance frameworks, enhancing transparency, and involving stakeholders. The authors emphasize the importance of addressing ethical implications and ensuring equitable access to AI-driven innovations in clinical oncology.
A combination of bazedoxifene and conjugated estrogens reduces obesity-related changes in rats, including fat cell accumulation and insulin resistance. The treatment also increases beneficial gut microbes and improves metabolic health, making it a promising alternative to tamoxifen for women at high breast cancer risk.
Researchers develop mathematical modeling to predict aflatoxin outbreaks in Texas using remote sensing satellites and soil properties. The model has the potential to save farmers billions of dollars in losses by providing early risk prediction and targeted prevention strategies.
Research found that bad habits like smoking, heavy drinking, and lack of exercise can lead to declines in health as young as 36, with effects more pronounced over the long-term. The study tracked hundreds of people for 30 years and found that three unhealthy behaviors were linked to poorer mental and physical health.
Researchers identify colibactin, a bacterial toxin that alters DNA, as a potential trigger for early-onset colorectal cancer. Exposure to colibactin in childhood may imprint a distinct genetic signature on colon cells, increasing the risk of developing cancer before age 50.
Researchers at Nagoya University found that patients with high-risk stigmata and invasive nodules in their pancreatic cysts had a significant impact on their survival. The presence of invasive nodules led to improved survival rates after surgery, while those without invasive nodules had favorable outcomes even without surgery.
Researchers from the UCLA Health Jonsson Comprehensive Cancer Center are presenting new findings on combination therapies for liver and pancreatic cancers, including a new organoid model for personalized head and neck cancer treatment. Additionally, they are discussing the potential of liquid biopsies for cancer detection and monitoring.
Researchers found that adults under 50 with migraine headaches and certain heart defects are at increased risk of stroke. The study highlights the importance of assessing both traditional and nontraditional risk factors in younger people to prevent strokes.
A new study published in The Journal of Internal Medicine found that having an unhealthy metabolic profile increases the risk of breast cancer recurrence by 69% and subsequent breast cancer mortality by 83% among survivors. This association was consistent across Europe, North America, and Asia.
A new study finds that a specific genetic variation in the PTGS2 gene is associated with an increased risk of benign prostate hyperplasia (BPH) in Lebanese men. Men carrying the C version of this gene were more than twice as likely to have BPH compared to those without it.
Researchers developed a saliva test that uses AI to identify genetic mutations in the DPYD gene, which can affect how well cancer patients respond to chemotherapy. The study found several new mutations that could lead to severe side effects from 5-fluorouracil, a widely used chemotherapy drug.
Current computed tomography (CT) imaging may lead to up to 103,000 future cancers over a patient's lifetime. If practices persist, CT-associated cancer could account for 5% of all new diagnoses annually.
A new study suggests that CT scans could account for 5% of all cancer cases each year, primarily due to radiation exposure. The largest risk is among infants, followed by children and adolescents. To mitigate this risk, reducing the number of scans and doses per scan can help save lives.
Researchers analyzed inherited genomes of 1,000 cancer patients to understand how germline variants impact protein function and physiological activities. The study identified rare and common cancer-causing genetic variants associated with increased cancer risk and disease severity.
Researchers found that Schistosoma haematobium parasitic infection triggers cancer-related gene activity in cervical lining, with treatment causing further changes. This study sheds light on how the parasite may contribute to cervical cancer risk at a molecular level.
A new American Cancer Society study reveals that adopting healthy lifestyles, as recommended by the organization's guidelines, can significantly lower cancer mortality risk among survivors. Researchers found that those who maintained a healthy lifestyle before and after diagnosis had a lower mortality risk compared to those with poor a...
Researchers at George Mason University have developed AI models that can predict cancer risk with accuracy rates of up to 90% for certain types of cancer. These models can enable risk-based screening recommendations, increasing access to life-saving cancer detection for high-risk patients.
New research published in the Journal of the American Heart Association suggests that even sporadic physical activity can have lasting health benefits, making it easier for people to prioritize their well-being amid busy schedules. The study found that completing 150 minutes of moderate to vigorous physical activity per week, regardles...
Researchers discovered that a high-fat diet activates mechanisms facilitating breast cancer metastasis by promoting platelet activation and fibronectin expression, creating a fertile breeding ground for tumor cells to take root. This study provides new insights into the relationship between obesity and breast cancer spread.
A survey by the Annenberg Public Policy Center found that over half of Americans believe drinking alcohol increases their chances of developing cancer. The Surgeon General's advisory on alcohol and cancer risk also contributed to increased public awareness, with nearly 3 in 10 respondents saying they would be less likely to accept a dr...
A study found that patient navigators significantly improved one-year follow-up colonoscopy completion rates by 12% and reduced time to follow-up by 27 days. The researchers emphasize the importance of timely follow-up colonoscopies for patients with abnormal stool test results.
A new study has found that a lower dose of the blood-thinning medication apixaban is as effective as the full dose in preventing recurring blood clots in patients with active cancer. Patients who received the lower dose experienced fewer bleeding complications and similar VTE recurrence rates compared to those on the standard dose.
A recent study by Edith Cowan University found that a combination of resistance exercise and aerobic exercise can significantly reduce pro-inflammatory biomarkers in women with non-metastatic breast cancer. The research suggests that moderate to high-intensity aerobic exercises twice weekly, combined with resistance training, may help ...
A growing body of evidence suggests a significant link between human papillomavirus (HPV) and heart disease. Researchers pooled data from nearly 250,000 patients in seven studies, finding HPV-positive individuals had a 40% higher likelihood of developing cardiovascular disease.
Patients with hormone receptor-positive and HER2-negative breast cancers face a higher risk of death from the cancer if they wait more than 42 days after diagnosis to have surgery. Delayed surgery increases the patient's risk exponentially, with risks of death increasing by 21%, 79%, and 183% at 60, 90, and 120 days, respectively.
New research suggests that maintaining a healthy weight throughout life and losing weight later in life may reduce the risk of kidney cancer. Higher BMI at various ages across adulthood was associated with increased risks of developing different types of kidney cancer, including renal cell carcinoma, papillary RCC, and chromophobe RCC.
A new study found that new-onset type 2 diabetes is associated with an increased risk of certain obesity-related cancers, such as bowel and pancreatic cancer. The study analyzed data from the UK Biobank and found a 48% increased risk in men and a 24% increased risk in women for overall obesity-related cancers.
A study published in The Journal of the National Cancer Institute found that waist circumference is a stronger risk marker than body mass index (BMI) for obesity-related cancers in men. However, this association was not observed in women.
A Swedish study of over 1,300 participants found that losing a significant amount of weight still offers protection against health issues like cancer and cardiovascular disease, even if some weight is regained. However, regaining weight can increase the risk of microvascular disease and other health problems.
A sub-analysis of 20-year follow-up data from the European Randomized study of Screening for Prostate Cancer (ERSPC) reveals that men who consistently decline prostate cancer screening appointments have a 45% higher risk of dying from the disease compared to those who attend screening appointments.
A recent study has found that people diagnosed with colorectal cancer are more likely to die from cardiovascular causes, particularly in the first two years after diagnosis. The study analyzed data from over 630,000 US adults and found a 16% increased risk of cardiovascular mortality among those with colorectal cancer.
Researchers found that detectable mutant KRAS circulating tumor DNA (ctDNA) indicates a higher risk of cancer spread and worse survival rates for patients with pancreatic ductal adenocarcinoma. The study suggests that ctDNA assays should be performed prior to treatment to have the highest yield.
A $1.2M grant will fund a comprehensive study on the potential links between neighborhood environment and cancer risk. The research team, led by Dr. Chris Lim, will analyze data from two ongoing studies to identify factors contributing to increased obesity-related cancer risk in specific neighborhoods.
A recent cohort study published in JAMA Internal Medicine found that statin use was associated with a reduced risk of hepatocellular carcinoma and hepatic decompensation in patients with chronic liver disease. This suggests that statins may play a role in preventing the progression of liver disease and reducing the risk of liver cancer.
A new study in the Circulation Journal reveals that babies born with heart defects may be at a higher risk of developing childhood cancer. Mothers of infants with congenital heart defects also show an increased cancer risk. The study highlights the importance of maternal factors and genetic traits in understanding this connection.
A new study found that birds have lower cancer rates despite high blood sugar levels, challenging existing assumptions. The research suggests that some species have evolved natural biological defenses against cancer, which could inspire new approaches to prevention and treatment in humans.
Excessive alcohol consumption causes severe digestive problems, including liver damage, stomach disorders, and increased cancer risk. Chronic alcohol use can lead to conditions like cirrhosis, pancreatitis, and colorectal cancer.
Researchers investigated skin cancer risk perceptions and sun-protective behaviors in US adults, finding associations between sociodemographic factors and sunburn risks. Higher education levels, Hispanic origin, and income groups were linked to lower sunburn risks, while married or partnered individuals had higher risks.
Genetic changes triggered by environmental factors like pollution, diet, and stress can increase cancer risk. Nearly everyone is exposed to cancer risk factors daily, highlighting the need for public awareness and policy action to reduce exposure.
Researchers found no clear evidence that red wine mitigates cancer risk, and instead observed a distinction in skin cancer risk. White wine consumption was associated with an increased risk of skin cancer compared to red wine, particularly among women. Heavy wine consumption may correlate to high-risk behaviors.
A new study reveals that firefighters are more likely to have a specific type of brain tumor with gene mutations linked to chemical exposure. The research found that firefighters were more likely to have the mutational signature associated with haloalkane exposure, especially those who worked for many years.
A study of nearly 2,500 postmenopausal women found that taking more daily steps and engaging in moderate-to-vigorous physical activity were associated with a significantly reduced risk of death from cardiovascular disease. Even walking fewer than 5,000 steps per day showed a risk reduction.
Researchers assess two approaches to test patients' hereditary cancer risks in primary care clinics, finding the point-of-care approach increases completion rates while the direct patient engagement method boosts testing rates among those eligible. The study's goal is to develop ways to improve uptake and reduce barriers to testing.