Articles tagged with Cancer Risk
A new study published in The Journal of Internal Medicine found that having an unhealthy metabolic profile increases the risk of breast cancer recurrence by 69% and subsequent breast cancer mortality by 83% among survivors. This association was consistent across Europe, North America, and Asia.
Researchers developed a saliva test that uses AI to identify genetic mutations in the DPYD gene, which can affect how well cancer patients respond to chemotherapy. The study found several new mutations that could lead to severe side effects from 5-fluorouracil, a widely used chemotherapy drug.
A new study finds that a specific genetic variation in the PTGS2 gene is associated with an increased risk of benign prostate hyperplasia (BPH) in Lebanese men. Men carrying the C version of this gene were more than twice as likely to have BPH compared to those without it.
Researchers analyzed inherited genomes of 1,000 cancer patients to understand how germline variants impact protein function and physiological activities. The study identified rare and common cancer-causing genetic variants associated with increased cancer risk and disease severity.
Current computed tomography (CT) imaging may lead to up to 103,000 future cancers over a patient's lifetime. If practices persist, CT-associated cancer could account for 5% of all new diagnoses annually.
A new study suggests that CT scans could account for 5% of all cancer cases each year, primarily due to radiation exposure. The largest risk is among infants, followed by children and adolescents. To mitigate this risk, reducing the number of scans and doses per scan can help save lives.
Researchers found that Schistosoma haematobium parasitic infection triggers cancer-related gene activity in cervical lining, with treatment causing further changes. This study sheds light on how the parasite may contribute to cervical cancer risk at a molecular level.
A new American Cancer Society study reveals that adopting healthy lifestyles, as recommended by the organization's guidelines, can significantly lower cancer mortality risk among survivors. Researchers found that those who maintained a healthy lifestyle before and after diagnosis had a lower mortality risk compared to those with poor a...
Researchers at George Mason University have developed AI models that can predict cancer risk with accuracy rates of up to 90% for certain types of cancer. These models can enable risk-based screening recommendations, increasing access to life-saving cancer detection for high-risk patients.
New research published in the Journal of the American Heart Association suggests that even sporadic physical activity can have lasting health benefits, making it easier for people to prioritize their well-being amid busy schedules. The study found that completing 150 minutes of moderate to vigorous physical activity per week, regardles...
Researchers discovered that a high-fat diet activates mechanisms facilitating breast cancer metastasis by promoting platelet activation and fibronectin expression, creating a fertile breeding ground for tumor cells to take root. This study provides new insights into the relationship between obesity and breast cancer spread.
A survey by the Annenberg Public Policy Center found that over half of Americans believe drinking alcohol increases their chances of developing cancer. The Surgeon General's advisory on alcohol and cancer risk also contributed to increased public awareness, with nearly 3 in 10 respondents saying they would be less likely to accept a dr...
A study found that patient navigators significantly improved one-year follow-up colonoscopy completion rates by 12% and reduced time to follow-up by 27 days. The researchers emphasize the importance of timely follow-up colonoscopies for patients with abnormal stool test results.
A new study has found that a lower dose of the blood-thinning medication apixaban is as effective as the full dose in preventing recurring blood clots in patients with active cancer. Patients who received the lower dose experienced fewer bleeding complications and similar VTE recurrence rates compared to those on the standard dose.
A recent study by Edith Cowan University found that a combination of resistance exercise and aerobic exercise can significantly reduce pro-inflammatory biomarkers in women with non-metastatic breast cancer. The research suggests that moderate to high-intensity aerobic exercises twice weekly, combined with resistance training, may help ...
A growing body of evidence suggests a significant link between human papillomavirus (HPV) and heart disease. Researchers pooled data from nearly 250,000 patients in seven studies, finding HPV-positive individuals had a 40% higher likelihood of developing cardiovascular disease.
Patients with hormone receptor-positive and HER2-negative breast cancers face a higher risk of death from the cancer if they wait more than 42 days after diagnosis to have surgery. Delayed surgery increases the patient's risk exponentially, with risks of death increasing by 21%, 79%, and 183% at 60, 90, and 120 days, respectively.
New research suggests that maintaining a healthy weight throughout life and losing weight later in life may reduce the risk of kidney cancer. Higher BMI at various ages across adulthood was associated with increased risks of developing different types of kidney cancer, including renal cell carcinoma, papillary RCC, and chromophobe RCC.
A new study found that new-onset type 2 diabetes is associated with an increased risk of certain obesity-related cancers, such as bowel and pancreatic cancer. The study analyzed data from the UK Biobank and found a 48% increased risk in men and a 24% increased risk in women for overall obesity-related cancers.
A study published in The Journal of the National Cancer Institute found that waist circumference is a stronger risk marker than body mass index (BMI) for obesity-related cancers in men. However, this association was not observed in women.
A Swedish study of over 1,300 participants found that losing a significant amount of weight still offers protection against health issues like cancer and cardiovascular disease, even if some weight is regained. However, regaining weight can increase the risk of microvascular disease and other health problems.
A sub-analysis of 20-year follow-up data from the European Randomized study of Screening for Prostate Cancer (ERSPC) reveals that men who consistently decline prostate cancer screening appointments have a 45% higher risk of dying from the disease compared to those who attend screening appointments.
A recent study has found that people diagnosed with colorectal cancer are more likely to die from cardiovascular causes, particularly in the first two years after diagnosis. The study analyzed data from over 630,000 US adults and found a 16% increased risk of cardiovascular mortality among those with colorectal cancer.
A $1.2M grant will fund a comprehensive study on the potential links between neighborhood environment and cancer risk. The research team, led by Dr. Chris Lim, will analyze data from two ongoing studies to identify factors contributing to increased obesity-related cancer risk in specific neighborhoods.
Researchers found that detectable mutant KRAS circulating tumor DNA (ctDNA) indicates a higher risk of cancer spread and worse survival rates for patients with pancreatic ductal adenocarcinoma. The study suggests that ctDNA assays should be performed prior to treatment to have the highest yield.
A new study in the Circulation Journal reveals that babies born with heart defects may be at a higher risk of developing childhood cancer. Mothers of infants with congenital heart defects also show an increased cancer risk. The study highlights the importance of maternal factors and genetic traits in understanding this connection.
A recent cohort study published in JAMA Internal Medicine found that statin use was associated with a reduced risk of hepatocellular carcinoma and hepatic decompensation in patients with chronic liver disease. This suggests that statins may play a role in preventing the progression of liver disease and reducing the risk of liver cancer.
Researchers investigated skin cancer risk perceptions and sun-protective behaviors in US adults, finding associations between sociodemographic factors and sunburn risks. Higher education levels, Hispanic origin, and income groups were linked to lower sunburn risks, while married or partnered individuals had higher risks.
A new study found that birds have lower cancer rates despite high blood sugar levels, challenging existing assumptions. The research suggests that some species have evolved natural biological defenses against cancer, which could inspire new approaches to prevention and treatment in humans.
Excessive alcohol consumption causes severe digestive problems, including liver damage, stomach disorders, and increased cancer risk. Chronic alcohol use can lead to conditions like cirrhosis, pancreatitis, and colorectal cancer.
Genetic changes triggered by environmental factors like pollution, diet, and stress can increase cancer risk. Nearly everyone is exposed to cancer risk factors daily, highlighting the need for public awareness and policy action to reduce exposure.
A new study reveals that firefighters are more likely to have a specific type of brain tumor with gene mutations linked to chemical exposure. The research found that firefighters were more likely to have the mutational signature associated with haloalkane exposure, especially those who worked for many years.
Researchers found no clear evidence that red wine mitigates cancer risk, and instead observed a distinction in skin cancer risk. White wine consumption was associated with an increased risk of skin cancer compared to red wine, particularly among women. Heavy wine consumption may correlate to high-risk behaviors.
A study of nearly 2,500 postmenopausal women found that taking more daily steps and engaging in moderate-to-vigorous physical activity were associated with a significantly reduced risk of death from cardiovascular disease. Even walking fewer than 5,000 steps per day showed a risk reduction.
Researchers assess two approaches to test patients' hereditary cancer risks in primary care clinics, finding the point-of-care approach increases completion rates while the direct patient engagement method boosts testing rates among those eligible. The study's goal is to develop ways to improve uptake and reduce barriers to testing.
A recent study by Professor Mamas highlights the significant risk of cardiovascular diseases (CVD) in patients with cancer, particularly in aging populations. The review emphasizes the need for early diagnosis and regular monitoring to improve quality of life.
Breast cancer mortality rates have stopped decreasing in two age groups: women under 40 and those over 74. This shift is attributed to an increase in stage IV breast cancers at diagnosis, leading to poor prognoses.
A risk prediction model was developed to identify patients unlikely to complete HPV vaccination. The model uses patient demographics and clinical characteristics to guide targeted interventions, increasing vaccination rates among high-risk groups.
Researchers create microfluidic device to sort tumor cells based on adhesive strength, revealing potential method to predict aggressive cancer behavior. The study's findings offer a promising approach for personalizing treatment plans and identifying high-risk patients.
A new study published in the European Journal of Preventive Cardiology found that a type of diabetes medication called SGLT2 inhibitors can significantly lower the risk of heart failure and hospital visits related to heart failure in cancer patients. The benefits were particularly promising for breast cancer patients receiving anthracy...
A survey reveals that most people are unaware of HPV's impact on cancer risk and its spread. The human papillomavirus (HPV) is more common among men than women, and the virus is associated with rising rates of oropharyngeal cancers, which can take years to develop after initial infection.
A large study of nearly 80,000 men found that those with better semen quality lived two to three years longer than those with poorer semen quality. The research suggests that poor semen quality may be an indicator of underlying health issues, and could potentially detect early signs of disease.
A new federal mandate aims to improve patient awareness about breast density, which affects cancer detection and risk. Women with dense breasts may need supplemental screening, such as MRI, to detect breast cancer earlier, but this comes with potential downsides.
Researchers developed a risk-prediction model based on four factors: family history, body mass index, sex, and smoking. A score equal to or greater than 9 indicates an above 14% likelihood of developing cancer or advanced precancerous lesions in adults under 45.
Researchers from the University of Southern Denmark found that tattooed individuals are more frequently diagnosed with skin and lymphoma cancers compared to those without tattoos. The study suggests that chronic inflammation in the lymph nodes triggered by tattoo ink may lead to abnormal cell growth and an increased risk of cancer.
A nationwide study found that patients with alcoholic liver disease have a significantly higher risk of developing colorectal cancer. The study highlights the importance of comprehensive CRC screening and risk stratification based on new consensus-based definitions of liver disease.
A UC Irvine-led study found associations between prenatal PFAS exposure and certain childhood cancers, including acute myeloid leukemia and Wilms tumors. Higher PFAS concentrations were linked to increased cancer risk in California children.
A pioneering study identified a crucial interaction between Helicobacter pylori and non-H. pylori bacteria in pre-cancerous stage of gastric cancer. Researchers found that bacterial leakage into deeper gastric tissues may represent a previously overlooked factor in cancer progression.
Researchers found that added sugars contribute between 7% and 21% to the risk of gastric cancer, while sodium intake is the main mediating factor. Healthy diets characterized by high vegetable and fruit consumption can reduce this risk.
A recent study published in JAMA Network Open has found that higher adherence to the Mediterranean diet is associated with a modest reduction in the risk of obesity-related cancers. The findings suggest that further research is needed to clarify the mechanisms by which the Mediterranean diet may contribute to cancer prevention.
A new study published in The Lancet Digital Health found that accelerated ageing in specific organs can predict diseases across the entire body. Organ ageing rates were linked to increased risks of various diseases, including cardiovascular disease, respiratory infections, and dementia.
Sylvester's Firefighter Cancer Initiative reduces cancer risk among firefighters and community members by addressing electric vehicle fires. A new gene-editing study aims to treat mitochondrial diseases, while a program connects patients with pathologists to improve understanding of complex results.
A new study found that breast cancer incidence in US women under 40 varies significantly across different states and regions, with the Western region experiencing the highest rate of increase from 2001 to 2020.
Groundbreaking research from the CLEAR study reveals that greater tumor shrinkage improves survival outcomes for patients with advanced renal cell carcinoma. The lenvatinib and pembrolizumab combination regimen demonstrates significant long-term benefits, including enhanced effectiveness of subsequent treatments.
ABT-263 eliminates harmful aging cells in the gut, reducing inflammation and lowering cancer risk in a mouse model of GI cancer. The study suggests that removing senescent cells could help prevent radiation-related GI cancer, highlighting the potential of senolytic drugs as a preventive treatment.
Amplified Sciences has received CLIA certification for its PanCystPro test, which helps risk stratify patients with pancreatic cystic lesions. The company plans to commercialize the test through an early access program and a clinical utility trial in 2025.
A new study from the University of East Anglia finds that European life expectancy has slowed down since 2011 due to factors such as poor diets, lack of physical activity, and obesity. The research suggests that prioritizing healthier lifestyles in younger years is crucial for extending old age.
A large-scale screen of single nucleotide variants has identified 380 variants controlling cancer-associated genes. These variants regulate biological pathways such as DNA repair, energy production, and cell microenvironment interaction. The findings suggest new therapeutic targets for preventing or stopping cancer growth.
A study found that 77.9% of lung cancer patients had detectable atherosclerosis on CT scans, with smoking being the most prominent cardiac risk factor. The results suggest using concurrent coronary calcium scoring to aid in identification and earlier intervention for these patients.
Researchers at The Jackson Laboratory have created an atlas of how healthy breast tissue ages, revealing key cellular and molecular changes that may contribute to breast cancer development. The study found that epithelial cells lose their job descriptions, becoming more prone to malignancy, while stromal cells lose their specialized id...