Articles tagged with Neurosurgery
Researchers discovered how anesthesia, surgery, and intensive care stress alter gene activity in the brain, leading to cognitive impairment and delirium. A new drug, vorinostat, reversed these changes, restoring memory formation and regulating the internal biological clock.
A comparative study examines autologous pericranium and G-Patch grafts in cranial duraplasty, finding fewer complications with natural grafts but no significant difference. The study highlights the need for larger multicenter studies to determine comparative effectiveness.
The study found that LVIS stent-assisted coiling provided effective aneurysm occlusion while producing measurable hemodynamic changes and maintaining procedural safety. Treatment reduced blood-flow activity within the aneurysm, with sustained improvements at 6 months.
Dr. Sepideh Amin-Hanjani, MD, FAANS, has been elected President-elect of the American Association of Neurological Surgeons (AANS), while Dr. Nicholas C. Bambakidis, MD, will become President-elect of the Society of Neurological Surgeons in 2027.
Researchers used real human brain tissue samples to test the underlying mechanisms of deep brain stimulation. They found that brain cells became more synchronized in communicating, similar to memory formation, while altering gene expression across different types of brain cells.
UC San Diego Health has been ranked as the top care facility in California and among the top 20 in the nation for eight medical specialties. The institution achieved this distinction through its patient-dedicated, collaborative spirit and commitment to delivering outstanding care.
A new study published in Chinese Neurosurgical Journal found that real-time MRI and brain function monitoring during neurosurgery can improve the removal of tumors affecting the corpus callosum more effectively and safely. This multimodal approach gave patients about 30 extra months after treatment before the tumor grew back or worsene...
A novel salvage surgical approach combining internal neurolysis and targeted glycerol injection has provided durable pain relief for a patient with severe, treatment-resistant MS-TN. The procedure was successful in preserving sensation and reducing medication use.
A young woman's quality of life and ability to walk were restored after a specialized procedure at Semmelweis University. The laparoscopic removal of a rare, benign tumor of neurological origin in the lesser pelvis, known as a schwannoma, was performed using intraoperative electrophysiological monitoring.
Researchers found that patients with Medicare Advantage insurance were more likely to receive certain types of stroke-preventing care and recover faster from strokes. In contrast, patients on traditional Medicare received more intensive post-stroke care and rehabilitation.
Researchers created a personalized adaptive DBS system that detects neural signals associated with each step and adjusts stimulation in real time, improving gait symmetry and reducing falls. The study demonstrates the potential for brain stimulation to adapt to behavior itself, opening doors to future therapies.
Researchers at UCLA Jonsson Comprehensive Cancer Center have been awarded a $3.2 million NIH grant to develop advanced imaging and surgical strategies for improving glioblastoma outcomes. The team aims to use pH-based imaging to guide precise tumor removal and explore targeted therapies that target the tumor's acid-regulating systems.
A multicenter clinical trial found that implanting collagen tiles during brain surgery improved tumor control and lowered the risk of recurrence by 12.1% compared to current standard of care. Patients treated with tile-based radiation therapy (TBRT) had a median overall survival of 42.5 months, more than double the 17.6 months seen wit...
A study published in Chinese Neurosurgical Journal shows that heat-based therapy, such as RF-TC, alters brain network connectivity in patients with medically refractory epilepsy. This may help predict treatment response and guide personalized interventions.
A new study published in the Chinese Neurosurgical Journal found that most basilar trunk artery aneurysms can be treated effectively using endovascular techniques, resulting in encouraging long-term recovery rates. However, larger aneurysms pose higher treatment risks and are associated with complications and poorer outcomes.
A study published in Chinese Neurosurgical Journal reports KRAS gene overexpression associated with brain arteriovenous malformation (bAVM) pathogenesis. The research found altered gene expression profiles linked to cell adhesion, signaling, and mitochondrial function, suggesting KRAS-driven molecular alterations play a role in bAVM de...
The new robotic system combines artificial intelligence, data-driven alignment planning, patient-specific implants, navigation, and robotic screw delivery to enhance precision and coordination. This technology streamlines operating room workflows, reducing procedure time and supporting recovery for patients undergoing spine fusions.
This review evaluates point-of-care (POC) biosensing strategies for ultra-early mTBI triage, focusing on platforms, matrix effects, and benchmarking aligned with CT-based decision-making. Key findings include the critical vulnerability of hemolysis elevating UCH-L1, and the importance of anchor development to the ED CT-triage use case.
A new clinical trial will investigate whether adding the oral medication vorasidenib to standard chemotherapy improves progression-free survival for people with newly-diagnosed, grade 3 IDH-mutant astrocytoma. The study aims to recruit 400 individuals with this type of brain cancer and evaluate the safety and side-effect profile of the...
Developed by CU Anschutz experts, the tool helps patients weigh treatment options and boosts confidence. The majority of patients reported it was helpful in their decision-making process, finding it useful and satisfied with the tool.
A prospective multicenter study found Woven EndoBridge therapy safe and effective for unruptured wide-necked bifurcation aneurysms in Chinese patients. The therapy promotes durable aneurysm occlusion with minimal risks.
A Chinese Neurosurgical Journal study developed a radiomics-based machine learning model to identify high-risk patients with traumatic brain injury who require emergency decompressive surgery. The model accurately distinguished patients who later required secondary surgery, suggesting its potential to complement clinical judgment.
A new AI-powered model can read a brain MRI and diagnose neurological conditions with up to 97.5% accuracy, predicting treatment urgency and automating alerts for immediate medical attention. The technology has the potential to transform neuroimaging at health systems across the US, reducing workload and improving patient outcomes.
The new intraoperative MRI technology enables real-time functional scans during neurosurgery, allowing doctors to detect complications and tailor their approach. This innovation saves time, labor, and improves safety and recovery for patients.
Researchers identified a crucial factor that may help improve treatment for glioblastoma, one of the most aggressive and common forms of adult brain cancer. They discovered a small molecule called miR-181d acts like a master switch that controls how much MGMT is produced by each glioblastoma cell.
Researchers developed a first-of-its-kind probe to track a fetus's vital signs in utero during surgery. The soft, flexible robotic probe provides accurate and precise measurements of heart rate, blood oxygen levels, and temperature, enabling faster interventions in case complications arise.
Researchers developed a SMaRT Score to predict shunt failures and need for revisions in children with hydrocephalus, based on analysis of medical records from 1,167 neurosurgical consultations. The score assigns points to various symptoms, with higher scores indicating a higher likelihood of shunt failure.
Researchers have developed a breakthrough light-responsive Janus dural patch using photocurable hyaluronic acid, providing strong wet adhesion and preventing unwanted tissue adhesion. The patch seals wounds within five seconds with minimal swelling and high biocompatibility.
The Rice Brain Institute has awarded seed grants to four collaborative projects that unite Rice faculty with clinicians and scientists across the Texas Medical Center. The grants support innovative research in brain science, mental health, and neurological disease.
A Northwestern University study found an injectable regenerative nanomaterial helps protect the brain during a vulnerable window after most common type of stroke. The therapy successfully crossed the blood-brain barrier and reduced brain damage, showing no signs of side effects.
Trigeminal neuralgia is a debilitating condition causing sudden, severe electric shock-like pain in the face. University Hospitals has successfully treated two initial patients with the OneRF Trigeminal Nerve Ablation System, providing complete pain relief without complications. The minimally-invasive procedure uses radiofrequency ener...
A study highlights how social media is transforming neurosurgical education, collaboration, and case consultations globally. Platforms like Neurosurgery Cocktail have democratized neurosurgical knowledge, supporting high-level discourse among experts.
Researchers at the University of Plymouth investigate why drugs used to treat other tumours are ineffective against NF2-related schwannoma and meningioma tumours. They explore repurposing clinically tested cancer drugs to target MDR mechanisms, which may lead to effective therapies for patients with these tumours.
Dr. Mintz brings exceptional clinical care, research, and education expertise to the role. He will lead transformative initiatives in perioperative operations, improving financial performance, employee satisfaction, quality, safety, and patient experience.
Philip R. Troyk, director of the Pritzker Institute of Biomedical Science and Engineering at Illinois Tech, has been elected as a Fellow of the National Academy of Inventors for his groundbreaking work on neuroprosthetic devices, including an implanted cortical visual prosthesis that provides artificial vision to individuals with profo...
Khalessi will shape UC San Diego Health's innovation strategy and lead the integration of new technologies, including AI. He aims to accelerate innovations supporting clinicians, patient safety, and operational efficiency.
The EBRAINS Summit 2025 will bring together experts to assess how neuroscience can drive medical progress, digital innovation, and responsible data use. Preliminary results from the EPINOV clinical trial, integrating virtual brain technology for epilepsy surgery planning, will be presented.
Researchers developed a new 3D surface scanning approach for precise brain surgery, outperforming CT scans in accuracy. The system eliminates radiation exposure and provides real-time guidance to surgeons.
Chronic subdural hematoma (CSDH) is projected to rise significantly due to aging population and increased anticoagulant use, with surgical interventions including twist-drill craniostomy, burr-hole craniostomy, and middle meningeal artery embolization. Emerging strategies like MMAE aim to reduce recurrence rates.
Researchers studied clinical features and treatment strategies for managing postoperative space-occupying cysts in brain tumor surgical sites. External drainage using an Ommaya reservoir or direct percutaneous puncture drainage showed favorable results, reducing cyst size and improving patient outcomes.
A new contactless optical-tracking registration method has been developed to simplify robot-guided SEEG surgery, reducing positioning errors and procedure time. The study demonstrates the accuracy and ease of use of this technique, making it a promising innovation in neurosurgery.
Researchers created BraDiPho, a 3D atlas of brain connections, combining clinical neuroscience, artificial intelligence, and neuroanatomy. The tool facilitates precise identification of white matter connections, opening up new therapeutic perspectives for neurological diseases.
A new, fully degradable cranial clamp made from poly-L-lactic acid has been developed to address traditional fixation system drawbacks. The study compared its performance to Aesculap CranioFix through laboratory tests and a clinical trial involving 90 patients, showing improved safety and healing outcomes.
Researchers at the University of Pittsburgh and UPMC developed a new treatment for patients with drug-resistant epilepsy. The approach uses deep brain stimulation (DBS) targeted to each patient's unique brain wiring, resulting in a significant reduction in seizures, with some patients becoming seizure-free for months.
Scientists found a promising candidate, pleiotrophin, which is essential for brain development and function; restoring it may improve brain circuits in individuals with Down syndrome and other neurological diseases. The study's findings suggest using modified viruses to deliver the protein directly into cells could lead to new treatments.
A study published in PLOS Biology found that surgically disconnected neural tissue in epilepsy patients exhibits slow-wave patterns similar to those observed during deep sleep or anesthesia, suggesting absent or reduced awareness. The persistence of these patterns raises questions about the functional role of slow waves in the brain.
A new system developed by researchers at Nagoya University can detect genetic mutations in brain tumors with high accuracy and speed. The system successfully identified key markers for diagnosis of diffuse glioma, a common type of brain tumor.
Researchers have quantified the costs of e-scooter injuries for the first time in Ireland, revealing an average cost of €1,726 per patient. The study found that e-scooter injuries mainly resulted in musculoskeletal injuries requiring major surgery, resulting in significant financial burdens on healthcare services.
A new study published in Biomaterials has developed a tiny, bioengineered system to deliver anti-inflammatory proteins to specific targets in the brain. The AstroCapsules, which are 300 micrometers in diameter, were confirmed to function when implanted into the brain and reduced neuroinflammation by measuring inflammatory biomarkers.
Researchers developed an integrated approach to solve the elective surgery assignment, sequencing, and scheduling problem (ESASSP), reducing delays and costs. The study suggests that hospitals can benefit from computationally efficient solutions to minimize operational costs and maximize resource utilization.
Researchers developed a fully automated finite element analysis pipeline to transform spine diagnostics and personalized treatment planning. The new approach enables rapid, patient-specific simulations that support preoperative planning, spinal implant optimization, and early detection of degenerative spine conditions.
Researchers developed a safe method to obtain prefrontal cortex biopsies during deep brain stimulation (DBS) surgery in living patients, demonstrating no increased risk of adverse events or cognitive decline. The study's findings establish the safety of this approach and open up new avenues for neuroscience research.
The procedure uses a combination of advanced imaging, artificial intelligence, and 3D printing to create a customized implant tailored to each patient's unique anatomy. This technology allows for more precise spinal alignment, reduced surgical complications, and faster recovery times.
Researchers achieved global-first using Brain Perioperative platform to learn how new drug suppresses tumour activity in low-grade gliomas, a slow-growing type of brain cancer. The trial involved patients who took the drug prior to any other cancer treatment and showed promising results.
Researchers developed a dynamic nomogram to predict long-term survival in patients with brain abscess, identifying key predictors such as age, Karnofsky performance status, and hemoculture results. The model offers an interactive tool for individualized risk assessment, facilitating better treatment decisions and improving outcomes.
A three-year-old girl has been successfully treated with the first-ever FDA-approved gene therapy treatment for AADC deficiency, a rare inherited neurological disorder. The treatment, Kebilidi, is expected to take 2-6 months to show measurable impact and has already shown signs of increased energy and happiness.
Researchers found that AI-augmented, personalized feedback from human instructors enhanced surgical performance and risk management. This study suggests the integration of human expertise in AI-driven education can improve engagement and ensure contextualized, adaptive feedback.
The new book Spinal Surgery Biomechanics: Principles for Residents offers a comprehensive exploration of core biomechanical concepts essential for mastering spinal surgical procedures. It bridges the gap between theory and practice, providing a biomechanical framework that supports surgical planning and patient safety.
A new study explores catheter-based polarization-sensitive optical coherence tomography (PS-OCT) as a tool for improving the precision of electrode placement in deep brain stimulation. PS-OCT provides high-resolution intraoperative visualization of deep brain structures, distinguishing between white and gray matter more clearly than MRI.
The Mount Sinai Hospital has been listed among the nation's top 20 hospitals for care excellence by U.S. News & World Report for 2025-26, with top-10 rankings in five specialties and top-20 rankings in nine. The hospital was also rated High Performing in all 22 procedures and conditions assessed by U.S. News.