Articles tagged with Heart
A new biotech company, Ibnova Therapeutics, will accelerate treatments for heart disease through cellular therapies, backed by Australian and Danish partnerships. The company aims to conduct human clinical trials within three to five years.
GLP-1 weight-loss drugs may prevent further tissue damage following a heart attack, significantly reducing the risk of further life-threatening complications. Researchers found that these drugs improve blood flow to the heart by activating potassium channels, relaxing constricted blood vessels and reducing heart damage risk.
Washington State University researchers identified a critical region in the leiomodin protein that regulates filament length, essential for maintaining a healthy heartbeat. The discovery may hold clues to future treatments of cardiomyopathies and other heart conditions.
A new study reveals that C-reactive protein is associated with ventricular arrhythmias in stable coronary disease, while its relationship with heart rhythms is different in patients with cirrhosis. In cirrhosis, only high white blood cell count shows a trend for linking to unstable rhythms.
A new study suggests that AI can help doctors detect serious heart valve disease years earlier, potentially saving thousands of lives. The AI algorithm correctly identified 98% of patients with severe aortic stenosis and 94% of those with severe mitral regurgitation.
Post-stroke spasticity affects an estimated 30-80% of stroke survivors, causing abnormal muscle tightness and involuntary spasms. Earlier diagnosis and timely intervention may improve functional outcomes and reduce long-term disability, according to the new scientific statement.
A recent study published in JAMA Internal Medicine found that oral semaglutide has a potential benefit in reducing heart failure events among people with type 2 diabetes and existing heart failure. The data support the use of oral semaglutide as a treatment option for these patients.
The FIU-Florida Heart Research Foundation Center for Innovation in Cardiovascular Health brings together experts in various fields to uncover the fundamental drivers of cardiovascular disease. The center will focus on AI-powered diagnostics, regenerative tissue technologies, and workforce development.
A recent study analyzed data from the Coronary Artery Risk Development in Young Adults (CARDIA) study and found that men developed coronary heart disease 10 years before women. The study indicates that this sex gap remains, with men having a higher cumulative incidence of cardiovascular disease and its subtypes.
A recent study from Penn State College of Medicine researchers found that helper T cells, typically involved in fighting infections, become overly activated in failing human hearts, causing damage. The activation of these T cells highlights the impact of inflammation and immune dysfunction in heart failure.
The PUMA trial will compare two invasive monitoring devices in open-heart surgery, with patient leaders guiding the research. The study aims to reduce unnecessary treatments, shorten ICU stays and cut healthcare costs.
Researchers have developed a new computational model that can analyze factors affecting the success of device installation and patient evolution. The model enables precise calculation of anticoagulant doses needed post-operation, reducing risk and improving safety for patients with atrial fibrillation.
A new study in Circulation: Population Health and Outcomes journal found that TV characters were more likely to receive CPR than real-life counterparts. This discrepancy highlights the need for accurate depictions of hands-only CPR on television.
Veteran male athletes over 50 are more likely to experience abnormal heart rhythms during training if they have scarring in their hearts. Exercise itself is not the cause, but can act as a trigger for dangerous heart rhythms in those with underlying heart issues.
Researchers at NIH and Emory School of Medicine have successfully performed a minimally invasive coronary artery bypass without cutting the chest wall. The new technique, called ventriculo-coronary transcatheter outward navigation and re-entry (VECTOR), creates a new route for blood flow that is safe from potential blockages.
A novel analysis found that financial strain and food insecurity accelerate biological aging and increase mortality risk, surpassing traditional risk factors. The study emphasizes the need for targeted preventive interventions and patient-centered care to address social determinants of health.
Adults with higher levels of physical activity during midlife and late life have a lower risk of all-cause and Alzheimer's disease dementia. This cohort study, part of the Framingham Heart Study Offspring cohort, found similar reductions in risk across different age groups.
A study comparing GLP-1 RAs found that all three drugs are relatively safe options for patients with type 2 diabetes, with minimal differences in kidney and cardiovascular risks. Liraglutide had a lower risk of all-cause mortality compared to dulaglutide.
A Cochrane review found that low-dose colchicine reduced heart attacks and strokes in people with a history of heart disease or stroke. The study involved nearly 23,000 participants and showed that taking colchicine could prevent about two of each heart attack and stroke among those with cardiovascular disease.
Researchers have identified connexin 43 as a vital protein for endothelial repair in mice, which could lead to new therapies to improve recovery and reduce complications after vascular surgery. The study found that the protein helps blood vessels recover after damage, suggesting it could be a target for treatments.
Researchers from NYU Langone presented practice-changing studies on inflammation, heart attack management, and kidney function in heart failure care. The findings highlight the importance of personalized treatment strategies and balancing effective care with monitoring of kidney health.
A new study found that middle-aged people with higher levels of cardiac troponin I in their blood were more likely to develop dementia in later life. The study also found that damage to the brain seen in people with dementia accumulates slowly over decades before symptoms develop.
A simple echocardiography method analyzes myocardial deformation to predict cardiac complications in chronic Chagas disease. The study found that patients with a greater GLS value had a higher risk of death and complications.
The American Heart Association's inaugural CarePlan Challenge recognizes innovators who create digital solutions that transform preventive care, improve disease management and enhance patient engagement. The selected solutions showcase integration of the Association's science-based CarePlans and other digital tools.
A new study analyzing linked electronic health records found that COVID-19 infections led to a higher and longer-lasting risk of rare heart complications, including myocarditis and thrombocytopenia, compared to vaccination. The research team estimated an additional 2.24 cases of myocarditis per 100,000 children after COVID-19 infection.
Researchers have discovered a previously unknown group of cells that produce adrenaline, which may help the fetal heart adapt to stress. The study provides a detailed map of the developing human heart, revealing over 70 distinct cell types and their interactions.
Researchers developed an algorithm to optimize pacemaker function usage, reducing battery power consumption and potentially extending battery life by years. By switching off unnecessary features, doctors can reduce the number of surgeries needed and lower associated costs for the NHS.
A new study published in The BMJ found that restricting sugar intake during early life is associated with lower risks of heart conditions in adulthood. People exposed to sugar rationing in utero and during their first two years had a 20% reduced risk of cardiovascular disease, as well as slower onset of heart problems.
Researchers used CRISPR technology to identify HMGN1, a nuclear binding protein that contributes to trisomy 21-related CHDs. The study found that an overabundance of HMGN1 leads to abnormal heart development and gene expression.
A landmark study analyzed health data from over 600,000 patients across 10 countries to assess patient risk for non-ST-elevation acute coronary syndrome (NSTE-ACS). The AI-powered model GRACE 3.0 predicts risk more accurately and guides personalized treatment decisions.
A new study from the University of Copenhagen enables researchers to investigate the cause of heart diseases by analyzing thousands of proteins in heart tissue. This groundbreaking method reveals molecular patterns characteristic of heart diseases.
Fitter individuals have lower resting heart rates and use fewer total heartbeats per day compared to sedentary people. Regular exercise can improve heart function and reduce long-term cardiovascular risk, according to new Australian research.
The American Heart Association has acquired the Cardiometabolic Center Alliance program, strengthening efforts to provide holistic management of cardiovascular, kidney, and metabolic health. This partnership aims to expand patient-centered care and improve outcomes for patients with cardiometabolic disease.
A new study found that pediatric athletes' cardiovascular systems adapt to increased fitness with abnormal changes, including increased cardiac mass, central blood pressure, arterial stiffness, and carotid intima-media thickness. These changes are not yet fully understood and may have long-term effects on cardiovascular health.
A multidisciplinary panel published in the Journal of Pediatrics advocates for accelerated diagnosis of familial hypercholesterolemia, a life-threatening genetic condition. Universal lipid screening is recommended to identify affected children at high risk of heart disease decades earlier than those without the condition.
Dr. Barbara Riegel will be honored for her pioneering research on self-care in patients with chronic illnesses, particularly heart failure. Her work has led to the development of the internationally recognized Self-Care of Heart Failure Index.
Research from the University of Copenhagen shows that exercising in nature improves mood, reduces stress levels, and boosts heart rate. Participants who exercised outdoors reported greater joy, satisfaction, and optimism than those who exercised in urban or indoor environments.
The new lab, led by Dr. Annapoorna Kini, will focus on leveraging AI in interventional cardiology, from procedural to educational aspects. The lab aims to optimize complex treatment decisions and improve patient outcomes through AI-powered insights.
Researchers have successfully tested drone-delivered Automated External Defibrillators (AEDs) for out-of-hospital cardiac arrests in the UK. The technology shows promise, but there were delays once the drone arrived on scene, highlighting the need for more support from bystanders and call-handlers.
A new study reveals that blood pressure synchronizes more with predictable phrase structures in music, potentially improving the body's ability to regulate blood pressure. Predictable music structures were found to have a bigger impact on blood pressure than tempo or loudness.
A case series of 19 patients has successfully undergone partial heart transplant, enabling valve growth and representing a novel approach to congenital heart disease treatment. Careful follow-up and monitoring are crucial for the continued expansion of this procedure.
A new study found that excessive visceral fat is linked to faster ageing of the heart, with a genetic predisposition to female-type fat in women potentially slowing heart ageing. Researchers also discovered that artificial intelligence analysis of images revealed signs of organ ageing, including tissue stiffness and inflammation.
The American Heart Association has named 15 students as national Youth Heart Ambassadors for the 2025-26 school year. These student ambassadors will promote healthy habits, raise awareness of heart disease and stroke prevention, and advocate for CPR education in schools.
NewYork-Presbyterian/Weill Cornell Medical Center has been recognized as a mitral valve repair reference center by the Mitral Foundation for three consecutive years. The award highlights the institution's commitment to delivering high-quality care and advancing best practices in surgical treatment of mitral valve disease.
Researchers are exploring whether wearable devices can detect early signs of cardiovascular disease through physical activity, sleep and blood pressure data. The study aims to develop a machine-learning model that uses data from wearable sensors to predict cardiovascular risk.
A personalized approach to recommending CPAP machines for patients with obstructive sleep apnea (OSA) may decrease adverse cardiovascular events. However, CPAP use can also increase cardiovascular risk for those with low-risk OSA markers.
A novel analysis confirms the benefits of regular walking at a faster pace in improving health, particularly for low-income and Black populations. The study found that fast walking as little as 15 minutes a day was associated with a nearly 20% reduction in total mortality.
A new study reveals that myosin binding protein-C (cMyBP-C) is essential for regulating cardiac muscle contraction, particularly under increased stress. The protein's absence or mutation can lead to diseases such as heart failure and hypertropic cardiomyopathy.
A systematic review found that optimal childhood heart health metrics, including diet, physical activity, and sleep, lead to lower risks of chronic diseases in adulthood. The review highlights the importance of early prevention and suggests that parents can focus on healthy habits and regular check-ups with pediatricians.
Leading media voice on health, Dr. Jennifer Ashton, and innovative Stanford cardiothoracic surgeon, Dr. Joseph Woo, join the American Heart Association's volunteer Board of Directors. They bring clinical leadership, scientific innovation, and health media influence to intensify efforts to improve cardiovascular health outcomes.
Researchers developed a new diagnostic method using Doppler ultrasound waveform to estimate toe brachial index (TBI), providing faster and more accurate results for early detection of peripheral artery disease (PAD). The study found eTBI to be consistent with standard TBI, detecting effectiveness of treatments in improving blood flow.
Scientists have identified a set of genes in zebrafish that reactivate after damage to the heart and patch it up like new. The researchers hope to use CRISPR tools to reactivate similar genes in humans and jump-start repair of the heart and other tissues after injury.
A new software tool called VR-Omics has the potential to further our understanding of other childhood diseases. The technology can identify previously undetected cell activities of cardiac rhabdomyoma, a type of benign heart tumour that can cause respiratory distress and irregular heartbeat.
A team of scientists has found that the ion channel PIEZO2 is crucial for coronary vessel formation and heart development. Without PIEZO2, coronary arteries may develop improperly, leading to oxygen supply issues in the heart muscle. This discovery could lead to earlier diagnosis and treatment of congenital heart defects.
Scientists at The University of Texas at Arlington identified a new enzyme, IDO1, that plays a crucial role in inflammation and cholesterol regulation. By blocking this enzyme, macrophages regain their ability to absorb cholesterol, offering a potential new way to prevent heart disease.
AIMP3 is essential to avoiding mistakes in protein synthesis, not affecting protein production, according to Brown University researchers. The discovery could lead to new treatments for heart diseases linked to homocysteine buildup and has implications beyond the heart.
PerDeCT is a device designed to monitor cardiac patients after surgery and provide early diagnosis of cardiac tamponade. The device aims to balance the benefit and risk of using devices to monitor cardiac output and detect tamponade easily, before damage is done.
A team of researchers from the University of Arizona College of Medicine - Tucson has identified a potential drug candidate for heart failure with preserved ejection fraction (HFpEF). The study, published in Cell Metabolism, found that a key ingredient triggering HFpEF is an enzyme that converts glucose into harmful byproducts, ultimat...
The PREVENT calculator improved estimates of heart attack risk when combined with coronary calcium score. Researchers analyzed nearly 7,000 adults and found that the PREVENT score matched the level of calcium buildup according to the CAC score.
Researchers created over 3,800 anatomically accurate digital hearts to investigate how age, sex, and lifestyle affect heart disease. They found that age and obesity cause changes in the heart's electrical properties, which could explain why these factors are linked to a higher risk of heart disease.