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A new approach to analyzing the morphology of dendritic spines

Researchers from Peter the Great St.Petersburg Polytechnic University propose a novel approach to analyzing dendritic spine shapes by considering clusterization methods. This approach can provide more accurate understanding of synaptic input and its relationship with learning, memory, and neurodegenerative disorders.

SourcePeter the Great Saint-Petersburg Polytechnic University·JournalFrontiers in Synaptic Neuroscience·DateOct 12, 2020

Sleep apnea linked with higher spine fracture risk among women

A new study published in Journal of Bone and Mineral Research suggests that women with a history of obstructive sleep apnea (OSA) are at a higher risk of developing vertebral fractures. The study found that OSA was associated with a 2-fold increased risk of vertebral fracture, particularly among those experiencing daytime sleepiness.

SourceWiley·JournalJournal of Bone and Mineral Research·DateSep 10, 2020

HSS doctors offer practical advice on reaching peak performance during surgical training

The article discusses the importance of peak performance in surgical training, citing the need for perseverance, stoicism, and grit. HSS physicians offer practical advice on achieving peak performance, including growing self-awareness through mindfulness activities and refining physical skills through deliberate practice.

SourceHospital for Special Surgery·JournalJournal of the American Academy of Orthopaedic Surgeons·DateSep 1, 2020

Researchers identify better classification system for adult idiopathic scoliosis

Researchers have designed a new X-ray classification system for adult idiopathic scoliosis, providing a more universal and standard assessment of the condition. The three-component method maintains existing curve types while introducing assessments of global alignment and lumbosacral curve, improving treatment options for older patients.

NIH study finds benefits of fetal surgery for spina bifida persist through school age

Children who underwent fetal surgery for spina bifida at a young age are more likely to walk independently and require fewer follow-up surgeries compared to those who had traditional corrective surgery after birth. The study found that these children also scored higher on motor skills and had lower rates of hydrocephalus.

How brain cells pick which connections to keep

Researchers at MIT's Picower Institute identified the gene and protein CPG15 that enables brain cells to select permanent synapses based on experience-driven neural activity. Without CPG15, mice exhibit slower learning and reliance on circuit architectures that haven't been refined by experience.

SourcePicower Institute at MIT·JournalCell Reports·DateAug 6, 2019

How the pufferfish got its wacky spines

Researchers have identified the genetic basis of pufferfish spines, which share developmental pathways with other vertebrates. The study reveals that the spines evolved as a unique adaptation for protection during inflation.

SourceCell Press·JournaliScience·DateJul 25, 2019

Researchers discover synaptic logic for connections between two brain hemispheres

Researchers at Max Planck Florida Institute for Neuroscience developed a new method to identify functional properties of individual synapses linking the two hemispheres. They found that callosal inputs and local inputs with similar orientation preference are clustered within the dendritic field, enabling coordinated network activity.

Scoliosis linked to essential mineral

A new study links scoliosis to the body's inability to utilize the essential dietary mineral manganese. Children with severe scoliosis are twice as likely to carry a gene variant that makes it hard for their cells to take in and use manganese, which is required for growing bones and cartilage.

SourceWashU Medicine·JournalNature Communications·DateOct 9, 2018

Thorny life of newborn neurons

Researchers found that frequent nerve signals strengthen dendritic spines in adult-born neurons, allowing them to connect with the existing neural network. This process is crucial for learning and memory formation in the hippocampus.

SourceGoethe University Frankfurt·JournalProceedings of the National Academy of Sciences·DateJun 8, 2018

Sustained use of opioids before spine surgery increases risk of continued use after surgery

A study published in The Journal of Bone & Joint Surgery found that patients who take prescription opioids for a longer period before spinal surgery are more likely to continue using opioids several months after surgery. Duration of opioid use before surgery was the main risk factor for continued use. After adjustment, the likelihood o...

SourceWolters Kluwer Health·JournalJournal of Bone and Joint Surgery·DateJun 7, 2018

First dynamic spine brace -- robotic spine exoskeleton -- characterizes spine deformities

The RoSE is a dynamic spine brace that measures 3-D stiffness of the human torso, enabling new treatments for children with spine deformities. The device applies controlled forces to correct abnormal curves, adapting to changes in the torso over time.

SourceColumbia University School of Engineering and Applied Science·JournalIEEE Transactions on Neural Systems and Rehabilitation Engineering·DateApr 9, 2018

Durotomy: A common complication of spinal surgery -- and an important factor in some malpractice cases

A study published in Spine Journal found that durotomy cases involving late detection and severe injury are more likely to result in a verdict in favor of the patient. The researchers identified 48 malpractice cases where incidental durotomy during spinal surgery led to litigation, with most resulting in a ruling in favor of the surgeon.

SourceWolters Kluwer Health·JournalSpine·DateDec 4, 2017

Nature's blueprint

Scientists at the University of Konstanz have created a more durable cement based on the nanostructure of sea urchin spines, which is significantly more resistant to fractures. The new material's elastic properties are comparable to those of mussel shells and reach values of up to 200 megapascals.

SourceUniversity of Konstanz·JournalScience Advances·DateNov 29, 2017

Study identifies genetic clues to spinal stenosis

A new study linked certain genetic changes to an increased risk of developing lumbar spinal stenosis. The research, involving 469 individuals, provides insights into the potential causes and may help identify patients at risk early.

SourceWiley·JournalJournal of Orthopaedic Research®·DateOct 13, 2017