Researchers distinguish multiple fluorescent proteins with overlapping emission colors by their lifetime using fluorescence lifetime imaging microscopy (FLIM). FLIM successfully distinguishes several fluorescent proteins with overlapping color emissions within plant cells, enabling simultaneous analysis of multiple proteins.
SourceInstitute of Transformative Bio-Molecules (ITbM), Nagoya University·JournalPLANT PHYSIOLOGY·TypeExperimental study·DateAug 11, 2026
Researchers used PET imaging to find significantly lower muscarinic acetylcholine M1 receptor availability in schizophrenia patients compared to healthy individuals. This study provides the first in vivo evidence of widespread M1 receptor deficits in schizophrenia, supporting the development of muscarinic-based therapies.
SourceElsevier·JournalBiological Psychiatry·TypeImaging analysis·DateJul 16, 2026
Researchers are developing an AI assistant to analyze petabytes of imaging data from high-resolution microscopes, which can track cells and molecular interactions in real-time. The goal is to help biologists understand complex biological systems and make new discoveries.
SourceUniversity of California - Berkeley·JournalNature Methods·DateMay 22, 2026
A new approach enables computers and machines to capture images at higher resolution and faster speed, making it impervious to reflective surfaces. The technology uses a virtual screen created by repurposing the surroundings of specular objects.
SourceUniversity of Arizona·JournalNature Communications·TypeExperimental study·DateMay 20, 2026
Celestron NexStar 8SE Computerized Telescope
Celestron NexStar 8SE Computerized Telescope combines portable Schmidt-Cassegrain optics with GoTo pointing for outreach nights and field campaigns.
Researchers developed multiplexed MRI technology, enabling simultaneous imaging of signals from multiple molecules in the brain. The technology provides a comprehensive view of the brain's structure, physiology, and molecular processes, allowing for more precise diagnosis and individualized treatment planning.
SourceUniversity of Illinois at Urbana-Champaign, News Bureau·JournalNature·TypeExperimental study·DateMay 6, 2026
Using AI-driven analytical methods, researchers have created a custom OCT system that enables the objective measurement of wound progress over time. The platform shows that stiffer mechanical properties improve wound healing outcomes, with faster transition to intact regenerated tissue.
SourceDuke University·JournalCell Biomaterials·TypeExperimental study·DateMar 20, 2026
Researchers at Kyushu University develop a new tissue-clearing reagent, SeeDB-Live, enabling repeated, reversible, and real-time imaging of living brains at greater depth and clarity. This breakthrough allows scientists to visualize neural activity in living mice and brain slices, offering new insights into brain dynamics and function.
SourceKyushu University·JournalNature Methods·TypeExperimental study·DateMar 12, 2026
Researchers developed a novel tool, CytoTape, to record temporal cell activities in situ along a flexible intracellular protein fiber. This technology enables scientists to view interactions on a large scale and over long periods of time, breaking through the tradeoff between resolution and scale.
SourceMichigan Medicine - University of Michigan·JournalNature·DateJan 26, 2026
Researchers at IIT develop optical microscopy technique that combines polarization and dark-field microscopy to observe cells with high contrast, preserving their natural conditions. The next step involves using AI to enrich images with molecular information related to diseases.
SourceIstituto Italiano di Tecnologia - IIT·JournalOptics Letters·TypeExperimental study·DateJan 15, 2026
SAMSUNG T9 Portable SSD 2TB
SAMSUNG T9 Portable SSD 2TB transfers large imagery and model outputs quickly between field laptops, lab workstations, and secure archives.
Researchers at Colorado State University used AI to modify antibodies into stable intrabodies that can visualize histone modifications in real-time. This allows for better understanding of gene expression and its relationship with cancer and other disorders. The team created 19 new antibody-based probes with a 70% success rate, signifi...
SourceColorado State University·JournalScience Advances·DateJan 12, 2026
A recent study published in Nature Communications reveals that the mechanical properties of the developing brain play a significant role in synapse formation and electrical signal emergence. The researchers found that softer regions exhibit higher synapse densities, while stiffer regions show lower densities.
SourceMax Planck Institute for the Science of Light·JournalNature Communications·TypeObservational study·DateNov 14, 2025
Researchers used zebrafish larvae to investigate visual function restoration following optic nerve injury. The study demonstrates that the contralateral eye supplies critical guidance cues for axonal regrowth and behavioral recovery, offering new perspectives on how neural circuits reorganize after injury.
SourceWenzhou Medical University·JournalEye and Vision·DateOct 24, 2025
Researchers at the University of Arizona are developing a new optical technology that can image deep into biological tissues without invasive procedures. This approach aims to overcome current challenges in skin cancer imaging, allowing for earlier detection, precise evaluation, and real-time monitoring of treatment response.
A new imaging approach has simplified retina exams by eliminating the need for mechanical focusing, making fundus cameras more accessible. The system uses a diffuser to capture 3D light information and digitally refocus images after they are taken, producing consistent resolution of about 7-10 line pairs per millimeter.
SourceSPIE--International Society for Optics and Photonics·JournalBiophotonics Discovery·DateSep 10, 2025
Davis Instruments Vantage Pro2 Weather Station
Davis Instruments Vantage Pro2 Weather Station offers research-grade local weather data for networked stations, campuses, and community observatories.
A new study using two-photon microscopy shows that brief interruptions in brain capillary flow can cause rapid drops in oxygen levels, potentially leading to tissue damage. The research found that even minor stalls can lead to significant hypoxia, highlighting the importance of uninterrupted blood flow to the brain.
SourceSPIE--International Society for Optics and Photonics·JournalNeurophotonics·DateSep 4, 2025
Scientists have discovered that tiny brain vessels pulse to regulate blood flow through bursts of contraction and relaxation. The research reveals that these bursts originate from the walls of small arteries and spread through the vascular network in short intervals, providing insights into how the brain regulates its blood supply.
SourceSPIE--International Society for Optics and Photonics·JournalNeurophotonics·DateSep 3, 2025
Researchers create breakthrough imaging system that shows sensory activity in real time, enabling them to distinguish between different sensations. The technique uses a genetically encoded voltage sensor to observe electrical signals from neurons and has major implications for treating chronic pain and sensory disorders.
SourceUniversity of Texas Health Science Center at San Antonio·JournalNature Communications·DateAug 6, 2025
A new mouse study uses advanced OCT imaging to reveal the fallopian tube's pumping mechanism in transporting preimplantation embryos towards the uterus. The study sheds light on the biological mechanisms underlying reproductive challenges like infertility and ectopic pregnancy.
SourceOptica·JournalBiomedical Optics Express·DateJul 15, 2025
Researchers have identified the medial prefrontal cortex (mPFC) as the basis of emotional inference in animals and humans. In a study published in Nature, Xiaowei Gu and Joshua Johansen found that rats can learn inferred emotions by associating a neutral stimulus with an unpleasant experience.
Fluke 87V Industrial Digital Multimeter
Fluke 87V Industrial Digital Multimeter is a trusted meter for precise measurements during instrument integration, repairs, and field diagnostics.
Researchers developed a live brainstem imaging method to study the nucleus tractus solitarii's role in emotion regulation and body-brain interactions. The D-PSCAN technique enabled high-resolution visualization of NTS neural activity in response to vagus nerve stimulation and gut hormone cholecystokinin, shedding light on potential the...
SourceNational Institutes of Natural Sciences·JournalCell Reports Methods·TypeExperimental study·DateMay 2, 2025
A new brain atlas developed by researchers at Duke University will increase precision in measuring changes in brain structure, making it easier to share results. The tool, the Duke Mouse Brain Atlas, provides a detailed map of the entire mouse brain, from large structures down to individual cells and circuits.
SourceDuke University·JournalScience Advances·TypeImaging analysis·DateApr 30, 2025
Researchers from OIST and Hebrew University developed a novel method to measure energy usage during movement using video and 3D-tracking via deep learning. This innovative approach expands the study of movement energy in ecology, physiology, and beyond, enabling the accurate measurement of energy consumption in smaller animal species.
SourceOkinawa Institute of Science and Technology (OIST) Graduate University·JournalJournal of Experimental Biology·TypeImaging analysis·DateApr 24, 2025
Researchers at Waseda University developed a new technique using terahertz imaging to visualize the internal structure of the mouse cochlea with high resolution. The study successfully demonstrated the potential of THz imaging as a non-invasive diagnostic tool for auditory disorders and other medical applications.
SourceWaseda University·JournalOptica·TypeImaging analysis·DateMar 27, 2025
DJI Air 3 (RC-N2)
DJI Air 3 (RC-N2) captures 4K mapping passes and environmental surveys with dual cameras, long flight time, and omnidirectional obstacle sensing.
Researchers have developed a non-invasive method to visualize the internal details of the mouse cochlea with micron-level spatial resolution using terahertz imaging. This technique has the potential to lead to a new diagnostic method for ear diseases and enable on-site diagnosis of hearing impairments.
Researchers have discovered a novel imaging tool that captures functional activity in mouse models of TMJ injury and inflammation, revealing the simultaneous activity of over 3,000 trigeminal ganglion neurons. This finding suggests that CGRP antagonists could offer a promising solution for TMJ pain relief.
SourceUniversity of Texas Health Science Center at San Antonio·DateMar 13, 2025
Researchers at Waseda University develop a new imaging technique that uses neutron activation to transform gold nanoparticles into radioisotopes, enabling long-term tracking of their movement in the body. This breakthrough could lead to more effective cancer treatments and precision monitoring of drug distribution.
SourceWaseda University·JournalApplied Physics Letters·TypeExperimental study·DateMar 12, 2025
Elizabeth Hillman, a pioneer in imaging method development, is leading the new Department of Imaging Sciences at St. Jude Children's Research Hospital. The department aims to develop innovative new imaging and measurement approaches that will enable groundbreaking scientific studies and improve patient care.
SourceSt. Jude Children's Research Hospital·DateJan 22, 2025
Researchers developed a supramolecular probe with enhanced phosphorescence properties for biological imaging and sensing. The probe demonstrated outstanding stability, biocompatibility, and specificity in viscosity response, enabling real-time visualization of critical physiological processes in cells and in vivo biosensing.
SourceScience China Press·JournalNational Science Review·DateJan 14, 2025
Sky-Watcher EQ6-R Pro Equatorial Mount
Sky-Watcher EQ6-R Pro Equatorial Mount provides precise tracking capacity for deep-sky imaging rigs during long astrophotography sessions.
A new experimental technique has developed a molecular flashlight to monitor molecular changes in the brain caused by cancer and other neurological pathologies. The technique uses vibrational spectroscopy to illuminate nerve tissue, allowing for the analysis of molecular changes caused by tumours or injuries.
SourceCentro Nacional de Investigaciones Oncológicas (CNIO)·JournalNature Methods·TypeExperimental study·DateDec 31, 2024
Scientists have designed bioluminescent proteins that can produce multiple colors of light for real-time imaging in cellular and animal models. These proteins are small, efficient, highly stable and can be used for non-invasive bioimaging, diagnostics, drug discovery and more.
SourceUniversity of California - Santa Cruz·JournalChem·DateNov 12, 2024
A $3.7 million NIH grant supports a study to improve PE diagnosis and treatment by using advanced imaging techniques, which may measure the effectiveness of clot-dissolving therapies. The goal is to help clinicians better diagnose and treat patients with PE, a devastating cardiovascular ailment.
A Korean research team has successfully observed living organoids in real time at a high resolution using holotomography. The technology allows for long-term observation of dynamic changes and precise analysis of organoid responses to drug treatments.
SourceThe Korea Advanced Institute of Science and Technology (KAIST)·JournalExperimental & Molecular Medicine·TypeMeta-analysis·DateOct 15, 2024
Apple iPhone 17 Pro
Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.
Researchers developed a new imaging technique using shortwave-infrared (SWIR) imaging to visualize the lymphatic system, improving resolution and sensitivity compared to traditional near-infrared (NIR) imaging. SWIR imaging with silver sulfide quantum dots offers superior image resolution and outperforms NIR-I imaging techniques.
SourceSPIE--International Society for Optics and Photonics·JournalJournal of Biomedical Optics·TypeObservational study·DateSep 30, 2024
Biomedical engineers at the University of Rochester have developed a novel technique using ultrasound waves to organize endothelial cells into patterns that promote the growth of new vessel networks. The team aims to treat ischemic injuries caused by damaged tissue in reconstructive and plastic surgeries.
Researchers developed a new two-photon fluorescence microscope that captures high-speed images of neural activity at cellular resolution, providing insights into brain function and neurological diseases. The microscope uses an adaptive sampling scheme to image neurons in real time, reducing damage to brain tissue.
A Rice University-led team is developing an affordable system to improve tumor removal accuracy for breast and head and neck cancer. The AccessPath system enables rapid, automatic tumor margin classification, revolutionizing real-time surgical guidance.
Creality K1 Max 3D Printer
Creality K1 Max 3D Printer rapidly prototypes brackets, adapters, and fixtures for instruments and classroom demonstrations at large build volume.
A new hybrid contrast agent has been developed to combine the benefits of MRI and PET imaging techniques, offering improved accuracy and opening new diagnostic applications. The agent has shown potential in detecting kidney problems and other conditions, paving the way for personalized diagnostics and precise imaging.
SourceInstitute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences (IOCB Prague)·JournalAngewandte Chemie·TypeExperimental study·DateAug 5, 2024
Researchers at Rice University have developed ultrasmall gas-filled protein nanostructures that can penetrate tissue and reach immune cells, opening up new possibilities for ultrasound imaging and drug delivery. The breakthrough could revolutionize treatment for cancers and infectious diseases.
SourceRice University·JournalAdvanced Materials·DateJul 15, 2024
A new microscopy system called mosTF enables fast and clear imaging of the living brain, improving tracking of rapid changes in neural circuit structure. The system outperforms traditional two-photon microscopy methods by eight times speed and four-fold signal clarity.
SourcePicower Institute at MIT·JournalScientific Reports·TypeExperimental study·DateJun 4, 2024
Aranet4 Home CO2 Monitor
Aranet4 Home CO2 Monitor tracks ventilation quality in labs, classrooms, and conference rooms with long battery life and clear e-ink readouts.
Researchers have identified collagen features as valuable biomarkers for evaluating melanoma immunotherapy response. Single-fiber characteristics were found to be more sensitive to treatment-induced changes than bulk collagen features, offering insights into collagen remodeling over time.
SourceSPIE--International Society for Optics and Photonics·JournalBiophotonics Discovery·DateMay 23, 2024
A new study shows that psilocybin initiates a pattern of hyperconnectivity in the brain linked to the ego-modifying effects and feelings of oceanic boundlessness. The findings provide insights into how the brain works on psychedelic drugs and their potential use to treat psychiatric disorders.
SourceElsevier·JournalBiological Psychiatry Cognitive Neuroscience and Neuroimaging·TypeImaging analysis·DateMay 23, 2024
Researchers developed a novel technique to visualize meningeal lymphatic vessels in vivo using photoacoustic microscopy. The study revealed that these vessels play a crucial role in regulating cerebrospinal fluid circulation and clearing metabolic waste from the brain, which is impaired in early stages of Alzheimer's disease.
SourceLight Publishing Center, Changchun Institute of Optics, Fine Mechanics And Physics, CAS·JournalLight Science & Applications·DateMay 6, 2024
Meta Quest 3 512GB
Meta Quest 3 512GB enables immersive mission planning, terrain rehearsal, and interactive STEM demos with high-resolution mixed-reality experiences.
Researchers developed a new method to accelerate high-resolution ultrasound localization microscopy using deep learning, enabling faster and more accurate imaging of microvascular structures. The technique, called LOCA-ULM, improves spatial resolution and processing speed while maintaining sensitivity for functional imaging.
SourceBeckman Institute for Advanced Science and Technology·JournalNature Communications·DateApr 22, 2024
Researchers from Osaka University have developed a new approach for super-resolution microscopy that can observe dense microstructures inside cells with excellent sharpness. By selecting only a desired plane to image using thin 'light sheet' illumination, they were able to achieve background-free super-resolution imaging.
SourceOsaka University·JournalNature Methods·TypeImaging analysis·DateApr 22, 2024
A new publication reviews optical scanning endoscopes based on a single multimode fiber, offering insights into their fundamental mechanisms, key performance metrics, and applications. The article discusses techniques to overcome modal scrambling properties and improves imaging resolution and contrast.
SourceCompuscript Ltd·JournalOpto-Electronic Science·DateApr 4, 2024
Researchers developed a new catheter-based device combining FLIM with polarization-sensitive OCT to image atherosclerotic plaques. The hybrid approach provides unprecedented information on plaque morphology, microstructure, and biochemical composition.
SourceOptica·JournalBiomedical Optics Express·DateMar 5, 2024
A team of scientists from the Beckman Institute has received a $3 million grant to develop diagnostic tools and imaging agents for the early detection of Alzheimer's disease. They will use a combination of PET and MRI scans to target smaller beta-amyloid peptides and other signs of neuroinflammation and oxidative stress.
SourceBeckman Institute for Advanced Science and Technology·DateFeb 5, 2024
AmScope B120C-5M Compound Microscope
AmScope B120C-5M Compound Microscope supports teaching labs and QA checks with LED illumination, mechanical stage, and included 5MP camera.
Researchers successfully reduced bladder tumor size by 90% in mice using nanorobots propelled by urea. The nanomachines deliver a radioisotope to the tumour, attacking it with precision and efficiency. This breakthrough could lead to more effective bladder cancer treatments and reduced hospitalization costs.
SourceInstitute for Bioengineering of Catalonia (IBEC)·JournalNature Nanotechnology·TypeExperimental study·DateJan 15, 2024
Ashok Veeraraghavan, a Rice University professor, has won the Edith and Peter O'Donnell Award in Engineering from the Texas Academy of Medicine, Engineering, Science and Technology. His research focuses on making invisible objects visible through imaging technology that tackles challenges beyond current technologies.
Researchers developed a method to measure microvascular changes in the skin using AI and optoacoustic imaging technology, enabling non-invasive assessment of diabetes severity. The study identified 32 significant changes in blood vessels, which can be used to monitor disease progression.
SourceTechnical University of Munich (TUM)·JournalNature Biomedical Engineering·TypeImaging analysis·DateDec 11, 2023
Apple MacBook Pro 14-inch (M4 Pro)
Apple MacBook Pro 14-inch (M4 Pro) powers local ML workloads, large datasets, and multi-display analysis for field and lab teams.
Researchers at UC Santa Barbara have created a novel method to measure osmotic pressure in living cells and tissues, allowing for the study of cellular behavior and its impact on organ function. This technique has promising industrial and medical applications, including monitoring skin hydration and diagnosis of diseases.
SourceUniversity of California - Santa Barbara·JournalNature Communications·DateNov 3, 2023
Researchers developed a new OCT approach to directly image coordination of tiny hair-like structures in live organisms, giving a powerful tool to investigate cilia's role in the female reproductive system. The technique revealed unexpected behaviors that contradict current views and suggested new roles for cilia.
Researchers developed an innovative imaging technique to study cells in bones of mice, revealing distinct pockets of bone resorption activity. This knowledge could lead to new treatments for osteoporosis and dormant cancer cells.
SourceGarvan Institute of Medical Research·JournalNature Protocols·TypeObservational study·DateOct 26, 2023
CalDigit TS4 Thunderbolt 4 Dock
CalDigit TS4 Thunderbolt 4 Dock simplifies serious desks with 18 ports for high-speed storage, monitors, and instruments across Mac and PC setups.
Researchers developed three new two-photon probes that can visualize organelles in cells, enabling better understanding of cellular functions and tissue imaging. The probes are designed to detect pH levels, viscosity, and ionic species, providing more specific insights into cell viability and treatment responses.
SourceUniversity of Cincinnati·JournalChemical Science·TypeExperimental study·DateOct 3, 2023
A new study explores how alpha-synuclein disrupts metabolic processes in neurons. Researchers used NanoSIMS imaging techniques to visualize isotopic variations and found changes in carbon turnover, suggesting increased metabolic demands on affected cells.
SourceEcole Polytechnique Fédérale de Lausanne·JournalActa Neuropathologica Communications·DateSep 28, 2023
Micro4PAP, a fast-scan Brillouin Microscope, allows for non-destructive, label- and contact-free imaging of biological samples. The device enables sub-millisecond acquisition time, suitable for in-vivo measurements in living cells, promoting early disease detection and diagnosis.
SourceIstituto Italiano di Tecnologia - IIT·DateSep 14, 2023
Researchers developed a noninvasive technique to visualize and differentiate nerve tissue using multispectral photoacoustic imaging. The study revealed the optimal wavelengths for identifying nerve tissue, which could improve nerve detection and segmentation techniques.
SourceSPIE--International Society for Optics and Photonics·JournalJournal of Biomedical Optics·DateSep 5, 2023
The research team created a multi-spectral, super-low-dose photoacoustic microscopy system with improved sensitivity, enabling new applications and clinical translation. The system achieved up to capillary-level or sub-cellular resolution at greater depths than traditional optical microscopy methods.
SourceCity University of Hong Kong·JournalAdvanced Science·TypeExperimental study·DateAug 31, 2023
Apple Watch Series 11 (GPS, 46mm)
Apple Watch Series 11 (GPS, 46mm) tracks health metrics and safety alerts during long observing sessions, fieldwork, and remote expeditions.
A research team at USTC realized single-pixel imaging of single living cells using 3D light-field illumination, achieving a resolution of up to 2.7 μm laterally and 37 μm axially. This breakthrough enables volumetric imaging of microscopic objects with high-performance 3D SPI.
SourceUniversity of Science and Technology of China·JournalProceedings of the National Academy of Sciences·DateAug 24, 2023
Researchers from Rice University and Princeton University have developed a new technology that allows for the live monitoring of signaling protein networks in living cells. The 'live reporter' system uses unobtrusive proteins to tag specific proteins, which can activate fluorescent markers when they become phosphorylated.
SourceRice University·JournaleLife·TypeExperimental study·DateJul 10, 2023