Scientists found that blocking microglia prevents infant forgetting and improves memory in mice, suggesting a role for microglia in memory formation. Microglia inhibition also enhances engram cell activation, providing a functional explanation for enhanced memory recall.
A new study published in Communications Psychology found that verbal justifications supporting memories remain rich, detailed, and consistent even after a delay of 24 hours. The study suggests that memory justifications provide a temporally stable window into episodic memory, making them a reliable basis for evaluating memory credibility.
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Researchers discovered that calcium alpha-ketoglutarate restores key memory-related brain functions disrupted in Alzheimer's disease. The molecule enhances synaptic plasticity, protects neurons from degenerative changes, and supports healthier cognitive ageing.
A study from the University of East Anglia explores how our brains remember past events and how those memories can change over time. Memories are made up of different parts and can become less accurate or include new information as they are retrieved.
The team aims to build an anonymized database representative of the whole population by collecting two vivid memories from participants. The findings will inform new ways to help people remember in more detail and understand human memories across the lifespan.
Researchers found that brain mechanisms for spatial attention differ when processing mental images from memory versus visuals on a screen. When recalling imagery, frontal areas are more active, suggesting distinct mechanisms for spatial attention in mental imaging.
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A global study by the University of Jyväskylä found that our most emotionally resonant music comes from our teenage years, peaking around age 17. This 'reminiscence bump' helps explain why songs from adolescence remain meaningful even decades later.
A new study reveals that astrocytes, a type of glial cell, are responsible for stabilizing memories through repeated engagement. The researchers found that Fos activity in astrocytes only occurs during recall, and that these cells can be activated to produce stable memories.
Researchers discovered that adults can better access their early memories after embodying a childlike version of their own face. Participants who viewed their childlike faces recalled significantly more episodic childhood memories than those who saw their adult faces.
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Eventgoers use social media to capture special moments and construct narratives of their own lives, intersecting with communal narratives. This mediated memory work influences how they experience and remember live events, blurring the lines between the present and future.
Researchers at Scripps Research uncovered structural hallmarks of long-term memory called an engram, which expands connectivity through specialized axonal terminals and alters synaptic architecture. This discovery could lead to new treatments for memory disorders.
Researchers suggest that learning different facets of information in each session and retrieving information from memory in various ways can lead to better memory retention. This method involves creating multiple paths to memorized information, which can be used to retrieve the information more effectively.
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The study found that slow electrical waves during deep sleep strengthen synaptic connections and make the neocortex more receptive to information. This enhances memory formation by creating a state of elevated readiness in the cortex.
Researchers Fernanda Morales-Calva and Stephanie Leal explored the three Ws of memory - what, where, and when - to understand why people remember certain things. They found that emotional content, personal significance, repetition, and attention can influence memory retention. The study highlights the importance of considering individu...
Researchers found a parallel pathway to long-term memory formation that bypasses short-term memory. Blocking short-term memory did not disrupt long-term memory retention.
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A study found that maternal immune activity during pregnancy affects offspring's long-term memory circuitry and function in childhood and midlife. Elevated levels of IL-6 and TNF-a in mothers were linked to adverse brain activity in memory circuitry, particularly in postmenopausal women.
A study from Tohoku University reveals that astrocytic manipulation affects the fate of long-term memory, with acidifying astrocytes preventing memories from being remembered and alkalinizing astrocytes preserving them. The findings suggest a parallel process of short-term and long-term memory formation.
Mount Sinai researchers discovered a neural mechanism for memory integration that involves replaying experiences, integrating new information with existing memories, and linking memories across time. This finding has implications for understanding adaptive and maladaptive memory processes, such as PTSD.
A study by Northwestern University found that cross-talk between the hippocampus and cortex can predict chronic pain, with higher anxiety levels increasing precision. The researchers suggest targeting anxiety after injury to prevent chronic pain, paving the way for novel treatments.
A new study from UT Arlington found that setting reminders can significantly reduce age-related declines in memory, particularly in prospective memory. The study suggests that reminders help counteract cognitive strain by making memory retrieval less reliant on internal processes.
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Studies show that the cerebellum is critical for forming stable memories for sensorimotor skills, largely independent of short-term memory systems. Researchers found that longer time intervals between trials increased reliance on impaired long-term memory.
Aging brains struggle to clear out outdated information, leading to slower processing and more frequent forgetfulness. Beta-band neural oscillations play a crucial role in regulating working memory, with older adults showing a stronger link between these oscillations and their ability to delete irrelevant information.
Researchers have uncovered new insights into how weak memories are strengthened through subsequent, non-related experiences, evoking strong responses. This process, known as heterosynaptic plasticity, challenges the traditional Hebbian model of learning and memory formation.
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The brain stores multiple copies of a single memory in parallel among different groups of neurons emerging at different stages during embryonic development. These memory copies change with time, with early-born neurons storing long-term persistence and late-born neurons fading over time.
A team of researchers from Penn State has identified HDAC3 as a key contributor to age-related impairments in memory updating. When blocked, older mice performed similarly to their younger counterparts, suggesting potential therapeutic targets for improving cognitive flexibility in old age.
A recent study published in BMC Psychology found that mild COVID-19 patients experienced significant cognitive impairment, with 11.7% showing memory loss and attention deficits. The study suggests that neuroinflammation due to SARS-CoV-2 infection may be a contributing factor to these long-term effects.
Researchers have uncovered the role of KIBRA in stabilizing memory formation through persistent synaptic tagging. This mechanism explains how memories can be stable for years despite constant cellular and molecular changes.
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A recent study revealed that the brain uses a similar neural mechanism to store faces of familiar individuals as it does to remember the value of objects. The striatum tail plays a critical role in this process, responding strongly to familiar faces and weakly to unfamiliar ones.
A University of Massachusetts Amherst study is tracking over 300 infants and preschoolers to assess the importance of napping on brain development. The research aims to identify the bioregulatory mechanisms involved in napping and its impact on memory, with findings expected to inform nap policies for young children.
A recent study published in Attention, Perception & Psychophysics found a correlation between pupil dilation and working memory. Researchers at the University of Texas at Arlington discovered that individuals with better working memory had larger pupil dilations during tasks, indicating improved focus and attention.
A UCLA Health study suggests Kundalini yoga can improve cognitive function, memory and brain health for postmenopausal women. The study found that yoga prevented brain matter decline, reversed aging and inflammation-associated biomarkers – improvements not seen in a group who received standard memory training exercises.
A new study found that unconscious reminders can strengthen memory, particularly when recalling associations between words and images. Unlike conscious reminders, which can lead to retrieval-induced forgetting, unconscious prompts facilitate a more nuanced process of memory consolidation.
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A recent study published in Nature found that smoking has a lasting effect on the immune system, with certain defense mechanisms persisting for up to 10-15 years after quitting. The research used a large cohort of healthy volunteers and identified three key factors: smoking, latent cytomegalovirus infection, and body mass index.
Researchers discovered a striking similarity between AI models and the human brain's hippocampus, which enables powerful AI systems. By mimicking the NMDA receptor's gating process, they improved long-term memory in Transformer models.
Researchers found that great apes and chimpanzees can recognize groupmates they haven't seen in over two decades, suggesting a shared common ancestor and potentially the longest-lasting nonhuman memory. The study uses infrared eye-tracking cameras to record participants' gazes at images of familiar and stranger bonobos or chimps.
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A study by the University of Ottawa found that various long-term memory types, such as semantic and episodic memory, rely on the same brain network to varying degrees. The research used neuroimaging techniques to compare brain activity across different memory conditions.
Researchers have identified a shared network of brain regions involved in various types of long-term memory, including general semantic, personal semantic, and episodic memory. The study found that these memory types rely on activating the same areas of the brain at differing magnitudes.
A recent study published in Nutrients found that daily strawberry consumption can improve cognitive performance and reduce depressive symptoms in middle-aged adults. The research, led by Professor Robert Krikorian, suggests that strawberries contain antioxidants and micronutrients that may help mitigate the risk of dementia.
A new study published in Neuron reveals that pericytes, a type of vascular cell, play a vital role in teaming up with neurons to form and store long-term memories. The research found that insulin-like growth factor 2 (IGF2) produced by pericytes enhances memory formation and storage.
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Researchers discovered protein p53's role in regulating sociability, repetitive behavior, and hippocampus-related learning and memory in mice. Lowering p53 levels led to changes in gene expressions related to behavior, while elevated p53 levels were linked to positive learning outcomes.
Researchers found that Period 1 gene becomes more active in memory-forming region of brain in daylight hours after learning, playing crucial role in consolidating memories. Mice exhibit improved daytime memory performance compared to nighttime.
Researchers propose a new mathematical neural network theory that consolidates memories to the neocortex if they improve generalization. This view contradicts the classical understanding of systems consolidation, which assumes all memories move from the hippocampus to the neocortex over time.
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A new study published in Aging (Albany NY) suggests that prior training can rescue cognitive decline in aging by improving task performance and strengthening memory processes. The research, conducted on rats, found that prior training enhanced short-term and intermediate memory, while also enabling encoding-boosted long-term memory.
A study published in JAMA Network Open found a significant association between food insecurity and accelerated memory decline in middle to older-age individuals. The researchers suggest that exposure to food insecurity in older age may have long-term negative effects on cognitive function.
Researchers found that neural networks grown in a dish can predict future stimulus events, with higher prediction efficiencies in focally stimulated networks. Focal electrical stimulation induced long-term memory traces and reduced dependence on short-term memory.
Researchers at KAUST developed smart digital image sensors that can recognize images with high accuracy, using a charge-trapping 'in-memory' sensor sensitive to visible light. The devices have an extremely long-lived retention time of up to 10 years and can perform optical sensing, storage, and computation.
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Researchers found that women with higher-quality cardiovascular fat during midlife had stronger long-term memory and lower inflammation, while those with lower-quality fat had worsening working memory. The study suggests that taking care of heart health during menopause may protect brain health and reduce dementia risk.
Researchers at the Institute for Basic Science have identified specific neurons in the hippocampus that allow us to recognize individual social counterparts and update their value through interactions. The dorsal CA1 region plays a crucial role in this process, enabling long-term memories of individuals to be formed.
A recent study of 30,465 adults without a history of heart attack or dementia found that those who experienced an MI had a faster rate of decline in global cognition, memory, and executive function compared to those without an MI. The study suggests that preventing heart attacks may be crucial for maintaining long-term brain health.
A study by Florida Atlantic University and CINVESTAV found that long-term running maintains the connectivity of adult-born hippocampal neurons, which contribute to memory function during aging. Exercise may prevent or delay age-related memory decline by increasing the survival and modifying the network of these neurons.
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A nine-year study led by Kyoto University found that critical thinking and logical decision-making promoted intelligent attitudes and risk literacy, reducing anxiety and food avoidance among citizens in Tokyo and Kansai regions.
The gene LRRC4 regulates synapse formation, stability and excitatory transmission, playing a crucial role in learning, memory formation and storage. It also has key implications in neuronal disorders and aggressive brain and spinal cord cancer.
Researchers at Albert Einstein College of Medicine have found that long-term memories are formed through cycles of transcription and local translation of a short-lived protein. The study provides insights into the causes of neurological disorders such as autism spectrum disorder and Alzheimer's disease.
Researchers discovered a mechanism that helps explain the link between reduced levels of protein PKMzeta and neurological disorders. The study used epigenetics to show that hypermethylation of the gene regulates its expression.
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Researchers used virtual reality to study how memories are selected for long-term storage, revealing the anterior thalamus as a crucial stopover site. Stimulating this region enhanced memory consolidation, while inhibiting it hindered long-term retention.
A new study identifies the anterior thalamus as a key brain region linking short-term to long-term memory. The thalamus plays a crucial role in memory consolidation, stabilizing memories from the hippocampus into long-term storage in the cortex.
Researchers found that suppressing AMPKα1 but not AMPKα2 isoforms improved aging-related impairments in mice. The study revealed novel insights into the roles of AMPK signaling pathway in cognitive aging.
Researchers have discovered a way to construct and control oxygen-deprived walls in nanoscopically thin materials, which can store data in multiple electronic dialects. These walls can retain their data states even when devices turn off, paving the way for next-gen electronics with enhanced memory capabilities.
Scientists at the University of Florida have discovered that long-term memories are formed through experience-dependent changes in protein sets, which undergo reorganization to encode the brain's circuitry. This finding provides insight into the brain's plasticity and has potential implications for understanding neurological disorders.
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Research found that experiencing three or more concussions is linked with worsened brain function in later life. Participants who reported multiple concussions showed significant cognitive decline, particularly in attention and complex task completion.