Researchers at The Hospital for Sick Children have developed new guidelines for pediatric clinical trial reporting, incorporating child and youth-focused considerations. The SPIRIT-C 2026 and CONSORT-C 2026 guidelines aim to improve the quality, transparency, and usefulness of pediatric RCT protocols and final reports.
A study suggests that obstructive sleep apnea affects around 1 in 5 adults in both countries, resulting in significant annual productivity loss. The estimated total annual productivity loss in the USA could be as high as US$180.2 billion, with an annual productivity loss of $3727 for each worker affected.
Researchers reconstructed diets of prehistoric communities in north-central Poland, shedding light on how people adapted to changing environments and social landscapes. The study found that Corded Ware communities herded animals in forests and that millet consumption varied among groups, reflecting identity and group boundaries.
Researchers at Washington University in St. Louis have created protein fibers that can exhibit high tensile strength, toughness, and mechanical stability, making them suitable for active wear and biomedical implants. The materials are grown using synthetic biology approaches and can be processed into a meat-like structure.
New research reveals that house fires release harmful compounds into the air, with synthetic materials like plastics and insulation contributing to higher levels of VOCs. However, their impact is often muted due to their small composition fraction in a typical home.
Researchers at FABI define a conserved subset of Phytophthora RxLR effectors with short linear motifs embedded within folded WY domain cores. This arrangement preserves domain integrity while enabling potential interactions with host immune components, reframing pathogen strategies and challenging SLiM dogma.
A new peer-reviewed study led by Dr. Hesham El-Askary finds significant vulnerabilities in the Grand Ethiopian Renaissance Dam's saddle dam due to leaks and seismic activity, posing a threat to downstream communities and infrastructure if urgent monitoring and mitigation steps are not taken.
Researchers develop mathematical model to capture microbial cooperation and community stability, predicting the outcome of experiments with E. coli strains. The model's results show that auxotrophs contribute to stable communities by trading essential nutrients and limiting growth.
A UBCO study found that all forms of touch with therapy dogs contribute positively to participants' emotional wellbeing, regardless of which part is interacted with. The research suggests that simple interaction with a therapy dog can make a difference in reducing stress and improving overall well-being.
Researchers used computer vision and machine learning to study Drosophila melanogaster courtship. They found that males rely on specific visual cues, particularly the female's eyes, to determine her anterior-posterior body axis. This recognition shapes when and how different elements of courtship are deployed.
The peer review process is facing a crisis due to an increasing number of manuscript submissions and a decline in willing peer reviewers. Researchers propose potential interventions to address this issue, including selecting high-quality reviewing and using machine learning to support editors. This could help maintain the credibility o...
Researchers will analyze existing clinical trials to identify biomarkers and treatments that promote healthspan, rather than just extending lifespan. Early findings suggest promising results from trials testing drugs that target the core biological drivers of aging.
The project aims to test whether reducing chronic inflammation triggered by DNA can help older adults stay healthier. The research focuses on retrotransposons, which become increasingly active with age, leading to tissue decline.
Utah engineers have created a wearable, portable hip exoskeleton that reduces the energy needed to walk by nearly 20% in individuals with hemiparesis after a stroke. The device helps compensate for reduced ankle propulsion and provides real-time motor assistance, improving mobility and quality of life.
A new study reveals that heat uptake fluctuations in the Aegean Sea during August predict Eastern Mediterranean winter rainfall. The Aegean Sea Heat Uptake Anomaly (AQA) index captures year-to-year rainfall variability and improves seasonal forecasting skill.
Research shows that small coral reef fish in the Arabian Gulf face a growing source of stress when oxygen levels drop at night, forcing them to use extra energy. The study's findings have important implications for the ecology and fisheries associated with coral reefs worldwide.
Researchers have discovered a new reactivity mode for phosphorus that mimics a mode performed by precious metal catalysts. This breakthrough could lead to more efficient and cost-effective methods for creating complex nitrogen-containing compounds in the pharmaceutical industry.
A new SFU study found fibreglass particles in the sediment and biofilm layers of the Cowichan Estuary, which supports shorebirds and shellfish. The researchers recommend immediate management actions to prevent further pollution from abandoned boats and marine infrastructure.
A new study reveals that shorter early-life telomeres are associated with higher survival rates in black-legged kittiwakes. In contrast, larger individuals tend to have shorter telomeres, suggesting a trade-off between growth and telomere maintenance.
A mathematical model suggests paths forward to stabilize peer review, as rising submissions imperil the process. The study identifies key factors contributing to the strain on peer reviewers.
A new Concordia research study refutes the notion that beaver dam failures can cause river flooding, arguing that failed dams had only a small effect on water levels downstream. The study found that natural conditions such as steep slopes and intense rainfall were more likely to cause damage.
Researchers at the University of Cincinnati found that female caribou gnaw on shed antlers to supplement their diets with calcium and phosphorus, essential for milk production. The study, published in Ecology and Evolution, reveals a previously overlooked benefit of shed antlers in the Arctic ecosystem.
After the pandemic, most museums continued offering online programs, with a focus on school programs for K-12 students. The shift was driven by partnerships between museums and public schools in need of digital content.
Researchers identified genes that are activated when yeast cells are in the gut, suggesting a roadmap for engineering more efficient drug-delivery vehicles. The study found that yeast cells were digesting more lipids than carbohydrates in the gut, highlighting potential modifications to improve efficiency.
Researchers identified over 70 medical conditions associated with Alzheimer's disease development, including endocrine/metabolic conditions like Type 2 diabetes. The study suggests that addressing these conditions in midlife may reduce Alzheimer's disease risk, and could lead to earlier interventions and improved patient outcomes.
A new study from the University of Surrey suggests that powerful companies risk legal responsibility for labor abuse, child labor, and environmental pollution linked to their global operations. Courts in the UK and abroad are treating corporate human rights responsibility as a legal duty rather than a voluntary promise.
Researchers found tirzepatide activates brown adipose tissue, improving metabolic energy burn and glucose/fat levels. This discovery opens new avenues for comprehensive obesity treatments with cardiovascular benefits.
A new study from the University of Surrey and Strathclyde University finds that customers' obsession with cheap travel is linked to low wages and harmful working environments for service staff. The research highlights evidence of widespread harassment of service workers, particularly among airlines and hospitality companies.
Researchers explore how METs convert organic waste into electricity, fuels, fertilizers, and usable water. Pilot deployments demonstrate its potential to reclaim energy from 359 billion cubic meters of wastewater annually.
Researchers have successfully isolated and grown authentic reservoir clones (ARCs) that evade the immune system, providing new insights into how to eliminate them. The study suggests that potent CTLs can catch these cells during brief windows of HIV visibility, slowly shrinking the reservoir.
A team of researchers from Illinois and UChicago has developed a novel way to compute the Hubble constant using gravitational waves, improving accuracy over prior methods. The new method uses background gravitational-wave hum from merging black holes in distant galaxies to learn about the age and composition of the universe.
Researchers have discovered six Bronze Age mining sites in southwestern Spain, revealing extensive metal extraction and trade networks. The findings provide a concrete archaeological context for previous studies on the origin of Scandinavian Bronze.
A new poll found that nearly half of Americans aren't aware that eating processed meat increases the risk of developing colorectal cancer. Two-thirds of adults would support warning labels on processed meat products after being informed about the connection.
A recent study by Heidelberg University suggests that countries with more comprehensive climate policy portfolios are achieving greater emission reductions. The research analyzed data from 43 major economies worldwide, finding that targeted policies, such as carbon taxes and renewable energy subsidies, were most effective in cutting em...
Scientists analyzed peatland samples to reconstruct 4,000-year history of storm activity in the northwestern Atlantic. The study found increased storminess in three periods: 800-550 BCE, 500-750 CE, and 1300-1700 CE, which aligns with eastern Canada records.
Governance scholar Christopher Koliba argues that the politicization of the COVID-19 pandemic and 2020 US elections led to a transgression of democratic accountability standards. The two crises undermined reason and truthfulness, forbearance toward democratic institutions, and professional discretion.
Researchers at Penn State have developed a bio-hybrid system that combines synthetic DNA with perovskite semiconductors to create a memory resistor that stores and processes data with minimal power consumption. This technology has the potential to enable more efficient data centers, speedier data processing and more complex data analysis.
A computer model identifies potential threats to over 10,000 freshwater species worldwide, offering a cost-effective way to safeguard species before they become endangered. The tool analyzes 52 variables, including damming, pollution, and habitat degradation, to recognize ecological patterns that benefit multiple species at once.
A new study finds that influencer culture affects girls' self-perception, with many recognizing the inauthenticity of online content yet still feeling pressured to conform. Researchers suggest that shifting attention away from individual girls and onto the culture that profits from their insecurity is key to change.
Ochsner Health System has expanded its specialty physicians and advanced practice providers to improve access to care for the Baton Rouge community. New physicians include Dr. Madeleine Dehner in family medicine, Dr. Victoria Page in ear, nose and throat medicine, and Dr. Maci Petite in women's health medicine.
Research reveals queer men in relationships are shifting from secretive to open approaches to sex and intimacy while traveling. Participants described 'monogamish' and 'open' relationship arrangements, with clear boundaries and communication crucial for avoiding problems.
A pilot initiative led by University College London is using highly detailed 3D scans to estimate tree structure, volume, and stored carbon in tropical rainforests. This data helps scientists better understand how much biomass forests contain, essential for tracking climate change.
A new material composed of rice grains can bend, buckle, or stiffen differently under slow movements versus sudden impacts without electronics or sensors. This innovative material has potential applications in soft robotics, creating machines lighter, safer, and more adaptable.
A new Surrey study found that rediscovered music often leads to radically different interpretations by performers, reshaping the work itself. The researchers compared professional recordings and used audio analysis software to track tempo and rhythmic fluctuation across the piece.
Researchers at UCLA have found a way to supercharge immune cells with a fuel source that tumors can't steal, dramatically improving their ability to survive and attack solid tumors. The approach enables T cells to import cellobiose and convert it into usable glucose inside the cell.
Researchers warn that AI's friction removal could eliminate desirable difficulties, weakening learning and motivation. Effortful engagement strengthens learning and memory, while loneliness serves as a signal to form human connections.
Alpha-gal syndrome is a growing concern in Missouri and beyond, causing delayed symptoms such as hives, stomach pain, and severe throat swelling. Mizzou researchers and MU Extension are working together to educate the public about alpha-gal syndrome and provide resources for those affected.
A team from Universitat Jaume I creates a biostimulant composition using proline particles encapsulated in silica, enhancing plant tolerance to drought, high temperatures and salinity. The new compound's production process is scalable, cost-effective and reproducible, with potential for industrial-level application.
The Endocrine Society's annual meeting ENDO 2026 offers journalists the opportunity to discuss groundbreaking research on various hormone-related topics with world-renowned experts. Over 7,200 attendees, 100 exhibitors, and nearly 2,500 abstracts are expected.
Research reveals that hunting pressure is shrinking safe space for mandrills in Equatorial Guinea's Monte Alén National Park. Mandrills are adapting to changing conditions by focusing on high-quality sites with limited human impact.
The Cacao of Excellence programme has announced its 2025 Edition, recognising 50 highest-ranking cacao producers from across four regions. The programme evaluates high-performing cacao through blind technical and sensory assessment, establishing an internationally comparable reference framework for cacao flavour.
Researchers develop a new approach to grow high-quality III-V active material on silicon in the form of ordered nano-ridge arrays, supporting symmetry-protected bound states in the continuum mode. This enables strong in-plane confinement and vertical surface emission from a compact device footprint.
A study found distinct inflammatory biomarkers and brain signatures for early-stage depression and psychosis, differing even in the earliest stages. These findings support customized therapies and may reduce risk of severe progression.
A new AI-driven system, LUMI-lab, has discovered a new class of mRNA-boosting lipids that enhance transfection efficiency. Brominated lipid tails were found to deliver mRNA into human lung cells more efficiently than approved benchmarks.
Researchers found that a bacterial metabolite regulates heart function through specific brain cells, revealing a new gut-brain-heart axis. This discovery points to potential therapies for hypertension and heart failure, and may serve as a biomarker for identifying patients at high risk.
This study found that US thyroid cancer overdiagnosis persists even after accounting for possible true incidence rises, highlighting opportunities to reduce unnecessary referrals and diagnoses
This systematic review found that both chemical and non-chemical denture cleansers effectively reduce Candida species, with chemical agents demonstrating more consistent antifungal action. Non-chemical agents preserve material integrity and are preferred by patients for their taste and ease of use.
A new study shows that valved holding chambers used to deliver medication to children with acute respiratory diseases differ markedly in their performance. The choice of device can affect treatment outcomes, with higher delivery devices resulting in lower hospital admissions and better physiological recovery.
The BfR Federal Institute for Risk Assessment is signing the Diversity Charter, a nationwide initiative promoting diversity in the workplace. The 'Year of Diversity' aims to anchor diversity and inclusion in everyday working life through participatory activities and regular dialogue.
A nationwide review of 373 reported drugging cases in Denmark found that alcohol was the most frequent substance detected in complainants' blood and urine samples. Blackout was also a common symptom, suggesting high levels of alcohol consumption.