Researchers found a mussel-derived compound strengthens resin-dentin bond and improves its durability. The compound, N-(3,4-dihydroxyphenethy) methacrylamide (DMA), reduces nanoleakage and increases longevity of dental fillings.
Researchers at the University of Louisville School of Dentistry found that oral bacteria like Porphyromonas gingivalis can suppress the production and effectiveness of proteins that protect humans from viral infection. This suppression increases vulnerability to infection, allowing viruses to enter the body more easily.
Researchers at NYU Dentistry will receive federal funding to implement an evidence-based model assessing and responding to family maltreatment incidents. The model, developed with the Air Force, improves fairness and reduces recidivism by nearly half.
A VCU-led study surveyed 216 dental faculty members, assessing personal and work-related burnout, resiliency, and loneliness. The study found average scores for burnout and loneliness, highlighting the need for dental schools to provide education, training, and incentives to reduce burnout and increase resilience among faculty.
A study found that many Medicaid-enrolled women in Virginia were unaware of dental pregnancy benefits, despite comprehensive coverage enacted in 2015. The survey revealed significant gaps in oral health knowledge among reproductive-age women by insurance status, with Medicaid-enrolled women facing barriers to care at higher rates.
Researchers identified a clear-cut seasonal pattern in respiratory viruses, with peaks in January and lows in June, affecting hospital admissions. The study found that babies born in severe peak years were more likely to be infected and hospitalized, highlighting the importance of planning ahead for high seasons of illnesses.
A UBC-led research team discovered that SARS-CoV-2 attaches to and deactivates galectin-8, a sensor protein that protects cells against infection. By disabling this defense system, the virus can hijack host cells to produce more viruses.
A recent study has called for reduced forceps use in Canada and better education for both clinicians and mothers on how to avoid injury during childbirth. The researchers analyzed nearly two million birth records from Canada, Norway, Sweden, and Austria, finding that five percent of women had third or fourth degree tears to the perineum.
A new spontaneous mouse model, McH-lpr-RA1, has been developed to study Sjögren's syndrome, an autoimmune disease affecting the tear system and salivary glands. The model exhibits autoimmune inflammation in the salivary gland tissue and blood vessels, destruction of the salivary gland structure, and inhibited salivary secretomotor system.
New research found that using electric drills instead of air-driven drills reduces aerosol spray by 99.98%, creating a safer environment for patients and dental teams. This could lead to a significant increase in treatments carried out, addressing the growing backlog of patients waiting for dental care.
A study published in Community Dentistry And Oral Epidemiology found that children with mothers suffering from postpartum depression or bonding disorders brush their teeth less often. In contrast, mothers showing strong affection towards their children increase the frequency of their child's toothbrushing.
Sylvia Frazier-Bowers, an Associate Professor at the University of North Carolina at Chapel Hill Adams School of Dentistry, has been awarded the AADR National Student Research Group Mentor Award. She is recognized for her efforts to bridge the gap between clinical profession and scientific advances in dentofacial variation research.
May Wong, Professor of Dental Public Health at the University of Hong Kong, was awarded the IADR Distinguished Scientist H. Trendly Dean Memorial Award for her significant contributions to dental research. Her work focuses on biostatistics, oral epidemiology, and clinical trials.
Martin Thornhill, a renowned professor at the University of Sheffield, has received the 2021 IADR Distinguished Scientist Award in Pharmacology/Therapeutics/Toxicology Research. He is recognized for his sustained contributions to dental and medical research, covering topics such as oral mucosa conditions.
Edward Chin Man Lo is the recipient of the 2021 IADR E.W. Borrow Memorial Award for his groundbreaking research on oral health prevention and caries prevention, with a focus on innovative approaches to fluoride utilization.
Bruno Loos, Academic Center for Dentistry Amsterdam, has received the IADR Distinguished Scientist Award for his outstanding research in periodontal disease. He is recognized for his contributions to the understanding of oral health and systemic health relationships.
Kiyoshi Koyano, a renowned prosthodontist, has received the IADR Distinguished Scientist Award for his outstanding research contributions to the field of prosthodontics and implants. He is recognized as a prominent scientist in Japan, with numerous international positions and publications on clinical practice and prosthodontics.
Fredrick Allan Clive Wright is the recipient of the 2021 IADR Distinguished Scientist Award in Geriatric Oral Research. He has made significant contributions to the knowledge of oral health in older people, general health relationships and effective geriatric oral care services.
David Williams, Professor of Global Oral Health at Queen Mary University of London, received the 2021 IADR Gold Medal Award for his work on oral health inequalities. He has developed a Standard Set of Adult Oral Health Outcome Measures and is a key figure in promoting sustainable growth and better global health outcomes.
Alvaro Della Bona, University of Passo Fundo Professor, received the 2021 Wilmer Souder Award for his contributions to dental biomaterials research. He is recognized internationally for his publications and invited presentations on the topic.
Rosa, an Associate Professor at NUS Faculty of Dentistry, received the award for his work on atom-thin materials for biomedical applications and dental pulp regeneration. He will serve a two-year term on the IADR Board of Directors.
A University of Alberta research team found that firefighters dealing with the massive 2016 Fort McMurray wildfire suffered from long-term lung damage, including increased bronchial reactivity and thickening. The risk of developing asthma was more than doubled compared to the general population.
Researchers identified three oral inflammation phenotypes: high, low, and slow responses. The 'slow' response was found in subjects with low clinical responses and demonstrated a delayed strong inflammatory response. A novel protective mechanism, utilizing neutrophils, was also discovered to save tissue and bone during inflammation.
A double-blind, randomized trial found that patients with severe obesity and metabolic syndrome had improved insulin sensitivity after receiving a fecal microbial transplant followed by daily fibre supplements. The study, led by Professor Karen Madsen, suggests that the microbiome can be targeted to improve human health.
The Journal of Dental Research has achieved the highest 2-year Journal Impact Factor over 6 for the first time at 6.116, ranking #5 in the Dentistry, Oral Surgery & Medicine category. The journal also ranks #1 in total citations and Eigenfactor.
A new study found that many younger adult dental patients are taking medications, highlighting the importance of reviewing medication histories. Medications such as antidepressants and opioids can increase the risk of dry mouth, tooth decay, and tooth loss.
New CONSORT-AI extension addresses limitations in AI study reporting, promoting standardization and improving the validity of AI studies in dentistry. With the growth of AI in clinical trials, standardized reporting is crucial to gauge methodology, bias, and replication.
Researchers found that SARS-CoV-2 infects immature red blood cells, leading to reduced oxygen levels and impaired immune response. The study also shows why dexamethasone has been an effective treatment for COVID-19 patients.
A machine learning algorithm, FARDEEP, has been developed to assess an individual patient's risk of regenerative outcomes after surgical treatments of peri-implantitis. The study found that immune cell types central to microbial control are strongly correlated with superior clinical outcomes.
Researchers discovered molnupiravir works by causing polymerase to make sloppy copies of viral genome, rendering them useless. The drug has shown promising results in eliminating SARS-CoV-2 infectivity in newly diagnosed patients after five days of treatment.
A team of University of Alberta researchers has discovered a way to use 3-D bioprinting technology to create functional cartilage in just four weeks, which can be used to restore nasal features in skin cancer patients. This method reduces the risk of complications and provides a more precise solution for reconstructive surgery.
Researchers have found a causal link between caesarean section birth and peanut sensitivity in infants, with effects more pronounced in children of Asian descent. Infants born by C-section were eight times more likely to develop peanut allergy by age three compared to those born vaginally.
A study by NYU College of Dentistry and Weill Cornell Medicine found that older adults with more harmful than healthy bacteria in their gums are more likely to have evidence for amyloid beta, a key biomarker for Alzheimer's disease. The researchers suggest that high levels of 'good' bacteria may be protective against Alzheimer's.
Experts recommend a more nuanced approach to COVID-19 vaccine prioritization, taking into account job site and neighborhood risks. At least 75% of Canadian adults have at least one risk factor for severe illness, highlighting the need for targeted vaccination strategies.
A team of University of Alberta researchers has identified a protein that blocks the body's ability to clear low-density lipoprotein (LDL) cholesterol from the blood. This discovery paves the way for developing a new drug to boost existing statin drugs and prevent heart disease.
A targeted opioid called NFEPP selectively activates opioid receptors in acidic tissues, relieving pain from colitis without causing severe side effects. Researchers are now collecting tissue samples to test NFEPP's ability to inhibit pain in the human gut and plan clinical trials.
A longitudinal study found that the ForsythKids preventive dentistry program reduced untreated cavities from 39% to 19% over six years, highlighting the effectiveness of school-based prevention programs. The study also highlights the critical need for accessible dental care in low-income communities.
A new pediatric heart transplant procedure has been shown to be at least as effective as the traditional approach, with similar survival rates and fewer infections. The method, pioneered by Canadian doctors, has enabled twice as many organs to be available for type O infants born with heart defects.
Researchers at UCLA discovered that deactivating a specific gene in cancer cells can significantly slow tumor growth and enhance the effectiveness of immunotherapy. The findings hold promise for developing more effective treatments for highly invasive head and neck squamous cell cancers.
Researchers successfully transformed oral epithelial cell rests of Malassez into progenitor stem-like cells, which were then directly differentiated into endothelial, mesenchymal stem, and osteogenic cells. This breakthrough could lead to the development of new periodontal regenerative therapies.
Researchers have confirmed histoplasmosis, a fungal infection transmitted through bat and bird droppings, is now found in Alberta, extending its known range northwest from the central United States and southern Ontario. Locally-acquired cases were primarily found in rural areas in central Alberta.
A new study will investigate a new way of reducing dental anxiety in children using Cognitive Behavioural Therapy (CBT). The study aims to improve oral health and save NHS costs by providing specially developed CBT resources for children, parents, and dental professionals.
A school-based cavity prevention program reduced untreated cavities by more than 50% among 6,927 elementary school students. The program, which provided twice-yearly dental exams and treatments, showed promise in reducing health disparities and saving federal dollars.
Researchers found that limiting fat release from fat cells during heart failure can reduce inflammation and improve cardiac function. In a study, mice treated with a drug blocking fat release showed better outcomes than control groups.
A new study from the University of Michigan School of Dentistry confirms that low-dose naltrexone is a good option for patients with orofacial and chronic pain, reducing pain intensity and improving quality of life. Low-dose naltrexone works by targeting sensitized nervous cells to reduce pain threshold and sensitivity.
Scientists identify critical enzyme KDM4B as key factor in skeletal aging and bone loss, leading to brittle bones and fractures. The study provides promising insights into the development of strategies to reverse bone-fat imbalance and prevent osteoporosis.
NYU College of Dentistry has been awarded a $1.9 million NIH grant to study the molecular mechanisms underlying mitochondrial permeability transition, a phenomenon that causes tissue damage during strokes and heart attacks. The research aims to develop new drugs that can protect against cell death and tissue damage.
Researchers Seiichi Yamano and Brian Schmidt aim to develop a new class of medicines using gene therapy to effectively treat oral cancer pain. They will test whether co-delivery of DNA and RNA can safely alleviate oral cancer pain, offering an alternative to opioids.
Researchers developed a machine learning tool to analyze brain scans and identify risk for earlier diagnosis and treatment. The tool accurately identified individuals with schizotypal personality traits at high risk of developing schizophrenia.
A new drug targeting enzymes involved in myristoylation has shown promise in treating both breast and blood cancers. Researchers found that patients with specific enzyme NMT2 were more likely to die, and the drug slowed tumour growth by 90% in mice with human breast cancer.
Research reveals that aerosol-generating procedures like fillings and root canal treatment can spray aerosol particles large distances, contaminating areas up to 5 meters away. The study found that dental suction decreases contamination, making it a suitable time to clean surgeries after procedures.
A study by Virginia Commonwealth University found that over 10% of dental hygiene students felt anxious about the future of dentistry, with 40% in their final year changing their career plans. Students who planned to change careers had higher stress and anxiety scores than those who didn't.
A recent study found that female COVID-19 patients experience less severe complications due to stronger immune responses triggered by their X chromosome-linked genes. Women's immune systems are enhanced by the presence of Toll-like receptor seven, allowing them to better tolerate virus infections.
The COVID-19 pandemic has underscored the importance of defining essential oral healthcare. A layered approach to essential oral healthcare allows for categorization and prioritization with available resources in mind, recognizing basic oral healthcare as an integral component of a healthcare system's essential services. The Internatio...
A University of Alberta study found that 35.9% of children diagnosed with COVID-19 showed no symptoms, raising concerns about school safety programs. The researchers also found that common symptoms like cough and runny nose were not reliable indicators of infection in children, emphasizing the need for vigilance and precautions.
Researchers found that nearly all insulation materials, except aerogels, were associated with chest infections. Insulators are also at risk of developing chronic obstructive pulmonary disease (COPD) from exposure to asbestos.
A review of academic studies found that nearly 20% of COVID-19 patients exhibit only gastrointestinal symptoms. Radiologists should be aware of signs such as bowel inflammation and air within the bowel wall, which could indicate advanced disease or COVID-19 infection.
A new study by NYU College of Dentistry found that half of US dentists experienced verbal or reputational aggression in the past year, while nearly a quarter endured physical aggression. The rates of patient aggression toward dentists are high and comparable with those reported in other health care settings.
Researchers at the University of Alberta have identified a new precision cancer drug for blood cancers that targets enzymes modifying proteins for cell signalling. The treatment, PCLX-001, has shown promising results in killing various types of cancer cells while leaving non-cancerous cells unharmed.
A team of scientists at the University of Toronto has discovered the mechanism linking periodontal disease to other inflammatory conditions. The study found that neutrophil immune cell activity is the key factor connecting gum disease to heart disease, cancer, and other inflammatory conditions.