Researchers aim to determine optimal duration and intensity of behavioral interventions for childhood obesity among rural and minority children. The five-year study, funded by the Patient-Centered Outcomes Research Institute, will enroll 900 parent-child pairs and compare different 'dosing' combinations of face-to-face intervention time.
Scientists from SLAC National Accelerator Laboratory have gained valuable insights into producing nitroxide, a molecule with potential applications in the biomedical field. The team employed advanced X-ray spectroscopic techniques to understand the intricacies of the nitroxide production process and its bond-breaking mechanism.
Alem & Narayanan receive $2,495,244 from the National Institutes of Health to enhance safety and quality of BSL-3 laboratory practices and create two new research cores in high containment. The grant will accelerate vaccine and therapeutic drug discovery and improve understanding of infectious disease transmission and pathogenesis.
Researchers from Icahn School of Medicine at Mount Sinai and the University of California San Diego will lead a new data integration hub aiming to accelerate novel therapeutics and cures for diseases. The grant, worth $8.5 million, is part of the NIH Common Fund's efforts to enhance data findability, accessibility, interoperability, an...
An international team of scientists recommends a global shift in food choices due to the potential for addiction. They suggest that certain ultra-processed foods have characteristics similar to addictive substances, which may improve global health.
Insilico Medicine has identified 9 potential dual-purpose targets against aging and 14 major age-related diseases using Microsoft BioGPT. The proposed genes include CCR5 and PTH, which have not been previously correlated to the aging process.
A team of researchers identified a protein called RAC2 that appears to drive the foreign body response, which causes the body to reject biomedical implants. Suppressing production of this protein could reduce the risk of implant rejection and improve the design and safety of implants.
Two renowned biomedical researchers, Professor Emile R. Chimusa and Professor Simon Johnson, have been awarded £1 million to conduct world-leading research into prostate cancer and mitochondrial disease. The grant will support the establishment of new interdisciplinary research teams and advance medical science.
The new facility will enhance the lab's capabilities to study the impact of chemicals and nanomaterials on human health, with applications in areas like toxicology and disease prevention.
The Louisiana Clinical & Translational Science Center has received a $1.3 million NIH grant to support the creation of a network of data warehouses for healthcare providers and researchers in Baton Rouge. The project aims to enhance research capacity, address health care disparities, and improve patient engagement.
The Fralin Biomedical Research Institute at VTC will accelerate health sciences research with a focus on cancer and brain disorders. The institute will recruit 14 researchers and support six major projects.
The research team created a multi-spectral, super-low-dose photoacoustic microscopy system with improved sensitivity, enabling new applications and clinical translation. The system achieved up to capillary-level or sub-cellular resolution at greater depths than traditional optical microscopy methods.
A study by Pennington Biomedical Research Center and Woman's Hospital found that pregnant women in Louisiana were more likely to exceed recommended weight gain levels during the pandemic, with a 3-7% increase. This rise in non-optimal gestational weight gain may have long-term impacts on maternal and infant health.
Researchers at UCLA have found that embedding study recruitment in pre-appointment check-in pages can increase participation rates up to 40 times higher than traditional methods. The new technique, called preCheck-in recruitment, resulted in a socio-demographically representative patient population without financial incentives or staff...
A recent study by Pennington Biomedical Research Center identifies GDF15 as a protein that acts as a cellular signal to enhance insulin secretion. High-intensity exercise training in patients with type 2 diabetes was found to have elevated levels of GDF15, associated with improved glycemic control.
Researchers at Binghamton University have developed genetically engineered nanovesicles that can target cancer cells more effectively than traditional chemotherapy. These nanocarriers can deliver therapeutic agents directly to the interior of cancer cells, reducing harm to healthy cells and increasing treatment efficacy.
Researchers created a database linking utility patents and NIH funding to assess translational efficiency. The Translational Ratio metric provides insights into patenting efficiency and its impact on drug innovation and treatment development. Institutions with strong engineering operations tend to be more successful in producing patents.
A new Northwestern Medicine study measures resilience in biomedical scientists during COVID-19, revealing that resiliency did not guarantee career advancement. The study found that women scientists faced greater household responsibilities and social pressure to advance their careers, leading to significant career setbacks.
The Kennesaw State University's BRITE program aims to diversify the biomedical engineering field by recruiting students from underrepresented groups. Students will participate in clinical settings, receive faculty mentoring, and work on interdisciplinary research teams.
Dr. Prachi Singh of Pennington Biomedical Research Center has received a $3.7 million grant from the National Heart, Lung, and Blood Institute to investigate the cardiovascular risks associated with limited sleep and extended eating duration.
Researchers from Binghamton University found that collagen fibers in skin become more tightly packed together, leading to increased stiffness and tissue hardness. This study sheds light on the biological mechanisms behind sun-induced skin changes.
A team of researchers has developed a scalable and efficient method to fabricate chitin hydrogels, which show promise for biomedical applications due to their biocompatibility and biodegradability. The fabricated chitin hydrogels possess excellent mechanical properties, high water content, and antifouling performance.
A 12-year study by Pennington Biomedical researchers found that metabolic surgery provides better results, less regression, compared to medical or lifestyle intervention for patients with class 1 obesity. The study showed significant improvements in glycemic control and weight loss, with high rates of diabetes remission.
A recent study published in Behavioral Sciences demonstrates the effectiveness of ACQUIRE Therapy in improving functional outcomes for children with various motor impairments. The framework provides a standardized approach to intensive therapy, emphasizing the importance of therapists' dynamic awareness and adaptability.
The Shape Up! Keiki research study aims to create a better way to measure and describe health from body shape, focusing on identifying obesity risks in young children. Participants aged 5 years or younger will be compensated $200 for their time.
A new partnership between Patrick Reed and Kenneth Eilertsen is putting a focus on translational research and commercialization at Pennington Biomedical. The team aims to evaluate patentability and marketability of potential disclosures, promoting public benefit from scientific discoveries.
McGill researchers are developing a new technique using 3D printing and hydrogels to create biomedical devices that conform to the human body. This emerging technology, called soft ionotronics, has the potential to improve wearable and implantable devices, such as strain sensors for neuromuscular rehabilitation.
The National Institutes of Health is enrolling 10,000 participants in a landmark precision nutrition study. The study aims to develop algorithms predicting how individuals respond to different foods and diets based on genetic, lifestyle, and environmental factors.
A novel protein nanoparticle vaccine candidate using adjuvants has been developed to boost effectiveness against viral infections. The study found that the vaccine provided complete protection against influenza viral challenges.
The 'Low Oxygen and Weight Status' study will investigate the effects of low oxygen levels on weight loss and health outcomes in adults with obesity. Participants will be randomized to sleep in an altitude tent or normal conditions, while following a weight loss diet. The study aims to inform new strategies for improving metabolic health.
The National Institutes of Health has awarded a $1.4 million Postbaccalaureate Research Education Program (PREP) grant to LSU Health New Orleans. The program aims to enhance the diversity of the biomedical sciences research workforce by preparing individuals from underrepresented backgrounds for PhD degree programs.
Impact Journals' Oncotarget participates in the AACR Annual Meeting 2023, highlighting its focus on oncology and biomedical sciences. The meeting theme of Advancing the Frontiers of Cancer Science and Medicine aligns with Oncotarget's research goals.
The new center aims to amplify biomedical research and human health applications, fostering collaboration among innovators. BRIC members will have access to resources and support for applying their nuclear physics expertise in new areas.
The Vilcek Foundation will award three Vilcek Prizes for Creative Promise in Biomedical Science to rising immigrant scientists. The prizes recognize and celebrate their contributions to their field.
Dr. David McDougal's research project aims to find better therapies to prevent hypoglycemic episodes in people with type 1 diabetes, focusing on the role of leptin in regulating blood sugar responses. The grant-funded study seeks to identify novel treatments for preventing low blood glucose in these patients.
Alejandro Sánchez Alvarado is awarded the Vilcek Prize in Biomedical Science for his groundbreaking work on regeneration. His research has significant implications for understanding cellular and organismal regeneration, with potential for further breakthroughs.
Researchers at Duke University have created a new approach to controlling cellular biochemical processes by building synthetic compartments that isolate biomolecules. This technique has the potential to be used to understand and fight disease, including the spread of antibiotic-resistant pathogens.
A global consensus has been reached on 19 open science practices to be implemented and monitored by biomedical institutions. These practices, including open access publishing and data sharing, aim to ensure transparent and accessible research.
A new study published in Cell Host & Microbe found that mice offspring from fiberolean mothers gained striking amounts of weight when fed a Western-style diet. The research suggests that microbial diversity plays a crucial role in obesity development, and that fiber is only beneficial if it's metabolized by beneficial bacteria.
A new undergraduate research program at the University of Arizona aims to address local health issues in Arizona using a community-based approach. The PHIRE program recruits 60 students annually for training in health informatics and places them in research projects relevant to their communities.
Researchers designed a small fluorescent protein that emits and absorbs light in the near-infrared spectrum, allowing for deeper and clearer biomedical images. The protein's ability to penetrate tissue enables the capture of detailed images of complex structures and cells.
Researchers at Brigham and Women's Hospital identified eutectic gallium indium (EGaIn) as a biocompatible liquid metal for biomedical applications. The team found that EGaIn can be formulated to break down in the body, providing a controllable end-of-life for devices like drug delivery systems and stents.
Researchers at CÚRAM developed an interdisciplinary framework to characterize ECM-based hydrogels, providing a concise guide for chemists, material scientists, and biologists. The review aims to bridge the gap between material science and biomedicine, facilitating further interdisciplinary work to create solutions for chronic illnesses.
Research found COVID-19 activates inflammatory response in the brain similar to Parkinson's disease, potentially leading to neurodegenerative conditions and new treatment approach with UQ-developed inhibitory drugs
The Beckman Institute has established a new national collaborative Biomedical Technology Research Resource to develop label-free optical imaging technologies. The center aims to create optical and computational imaging technologies that can serve as a resource for clinicians and researchers.
Virginia Tech researchers found that a common oral bacterium, Fusobacterium nucleatum, drives pancreatic cancer cell proliferation and migration. The bacterium can infect normal pancreatic tissue cells, stimulating nearby cancer cells to grow and spread rapidly.
The Vilcek Foundation has awarded $250,000 in prizes to four leading immigrant scientists: Alejandro Sánchez Alvarado, Edward Chouchani, Biyu J. He, and Shixin Liu. They received the 2023 Vilcek Foundation Prizes in Biomedical Science for their groundbreaking work in regeneration, metabolic disease, cognitive neuroscience, and nanoscal...
A new study found that scientists tend to be most innovative and creative early in their careers, with a significant decline in impact over the course of their careers. The study analyzed 5.6 million biomedical science articles and found that the work of less-innovative researchers tends to drop out as they get older.
The Bioteque computational tool integrates vast amounts of biological data, providing insights into gene functions, protein interactions, and disease connections. By analyzing over 30 million functional interactions, the tool can predict drug sensitivity and accelerate biomedical research.
A new project aims to develop resources and AI models to assess biomedical publications for citation accuracy and integrity, benefiting researchers, journals, and policymakers. The project, led by Associate Professors Halil Kilicoglu and Jodi Schneider, received a $300,000 grant from the US Department of Health and Human Services.
The ‘YES Oklahoma’ project seeks to address the underrepresentation of American Indian students in biomedical and cancer research. The program aims to provide research training opportunities for high school students, teachers, and graduate students from underrepresented communities, with a focus on improving community health outcomes.
The program, one of only 18 nationwide, will support eight Ph.D. students and five postdoctoral fellows each year for five years, focusing on biomedical informatics and data science. The grant is the seventh renewal of support for a multidisciplinary training program that began over 30 years ago.
The NCI-backed Molecular Targets Platform streamlines and catalyzes drug development by integrating pediatric cancer targets and pathways. This platform empowers researchers, pharmaceutical companies, and advocacy groups to accelerate the pace of drug development for pediatric cancer.
Binghamton University researchers have developed a way to turn CDs into flexible biosensors that can monitor electrical activity in human hearts and muscles, as well as lactate, glucose, pH, and oxygen levels. The sensors are fabricated in 20-30 minutes without toxic chemicals or expensive equipment, costing around $1.50 per device.
A new study published in Redox Biology reveals that white adipose tissue is the most vulnerable organ to obesity-related metabolic changes. The study shows that when physiological stress exceeds the capacity of white adipose tissue to respond, it loses its metabolic plasticity, leading to a snowball effect on metabolic dysfunctions.
Biomedical engineers have created a novel 3D synthetic structure that mimics the extracellular matrix, guiding neural progenitor cells and promoting their differentiation. The results show promise for developing brain-healing treatments, including biogels that can repair and regrow brain tissue after a stroke or other trauma.
The Heart and Lung Research Institute (HLRI) at the University of Cambridge will bring together over 380 researchers and clinicians to tackle cardiovascular and respiratory diseases. The institute aims to deliver high-impact research to drive breakthroughs in prevention, early diagnosis, and treatment of these diseases, which represent...
A global team led by Rutgers Cancer Institute of New Jersey has secured $25 million to study cachexia, a debilitating wasting condition responsible for up to 30% of cancer deaths. The team plans to build a deep understanding of what causes cachexia and develop novel treatments.
The new technique, 3D optical coherence refraction tomography (3D OCRT), produces highly detailed images revealing features difficult to observe with traditional OCT. It has the potential for biomedical research and eventually more accurate medical diagnostic imaging.
Researchers at Georgia State University have been awarded over $6 million to develop antiviral drugs targeting COVID-19 and other viral threats. The funding will support the establishment of a new Midwest Antiviral Drug Discovery Center, which aims to build a pipeline of antiviral drugs.