A new study finds that girls with autism often struggle more than boys with performing routine tasks and making small talk, even when standardized tests are normalized for sex. This suggests that girls with autism may be 'camouflaging' their symptoms, leading to delayed or missed diagnoses.
SourceChildren's National Hospital·JournalJournal of Autism and Developmental Disorders·DateJan 4, 2018
The new journal will publish evidence-based original articles, review articles, and analysis on various aspects of adult autism, including physical and mental health, research methodology, and policy change. The journal aims to provide authoritative insights and promote practice, systems, and policy changes for adults with ASD.
SourceMary Ann Liebert, Inc./Genetic Engineering News·JournalAutism in Adulthood·DateDec 15, 2017
Research led by Professor Stephen Wood at Orygen found that individuals with autism traits and psychosis are at a greater risk of depression and suicidal thoughts. The study suggests that identifying autism traits can help identify those most at risk of suicide, highlighting the need for better training and assessments.
A new virtual child software is being developed to train professionals in behavioral intervention techniques for children with autism spectrum disorder. The software will feature a virtual child programmed with learning difficulties associated with autism, allowing users to practice and master treatment methods.
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Researchers at Weizmann Institute of Science found that individuals on the autism spectrum exhibit distinct reactions to 'smells of fear' and 'calm sweat', including changes in anxiety levels. This suggests a possible underlying connection between smell, social cues, and early brain development in autism.
SourceWeizmann Institute of Science·JournalNature Neuroscience·DateNov 27, 2017
A study published in Autism Research found a correlation between shorter time intervals between pregnancies and increased risk of Autism Spectrum Disorder in second-born children. The researchers suggested that couples planning pregnancy should discuss their options with a trusted doctor or healthcare provider.
Researchers found that social and emotional exclusion in mainstream schools can lead to increased isolation and low self-esteem in pupils with autism. Creating a culture of acceptance is crucial for long-term wellbeing.
Researchers have tested a potential new drug, NitroSynapsin, in a mouse model of an autism disorder and found it largely corrected electrical, behavioral and brain abnormalities. The candidate drug is intended to restore the signaling imbalance found in virtually all forms of autism spectrum disorder.
SourceScripps Research Institute·JournalNature Communications·DateNov 14, 2017
The Azrieli Centre for Autism Research will foster innovations in therapy and a better understanding of autism spectrum disorder. Researchers will use advanced brain imaging techniques to map differences in children and adults living with ASD, leading to earlier diagnosis and effective intervention.
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Researchers discovered a genetic cause of autism that affects male mice more severely than females, leading to abnormal reward-learning behavior. This study sheds light on the sex differences in autism and may lead to new treatments for the disorder.
SourceUniversity of Iowa Health Care·JournalMolecular Psychiatry·DateOct 17, 2017
Researchers have discovered a new genetic signature for autism by analyzing the genomes of 516 autistic children and their families. The study found that individuals with autism are more likely to have multiple genetic variations, suggesting a complex interplay between genes in the development of the disorder.
SourceHoward Hughes Medical Institute·JournalCell·DateOct 12, 2017
A Drexel University-led study found that multivitamin use during pregnancy may reduce the risk of autism with intellectual disabilities by 30%. The study, published in BMJ, looked at data from over a decade and controlled for other factors. However, more research is needed to clarify the relationship between diet and autism development.
The largest study to date finds a significant difference in autism recurrence risk based on sibling gender. Boys are more susceptible to autism, especially when an older female sibling has the condition. Meanwhile, female siblings with older brothers have lower risks.
SourceHarvard Medical School·JournalJAMA Pediatrics·DateSep 25, 2017
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Researchers have identified networks of genes related to autism spectrum disorder (ASD) that may also be involved in cancer, potentially leading to new treatment options. The study used a computational technique to account for gene interactions, revealing genes that could affect similar pathways.
SourceFrontiers·JournalFrontiers in Genetics·DateSep 25, 2017
Researchers found eight mutations associated with autism in the TRIO gene, which can lead to weaker or stronger connections between brain cells. Weaker connections may hinder information storage and processing, while stronger connections cause trouble communicating between brain cells.
SourceUniversity of Southern California·JournalNature Communications·DateSep 19, 2017
Researchers at the A.J. Drexel Autism Institute are studying the benefits of early detection of autism through a $11.4 million grant from the National Institutes of Health. Early detection is critical for improving outcomes in social and cognitive functioning, as well as mitigating disabilities over a child's lifetime.
Researchers suggest that reversing excitation-inhibition imbalance could alleviate autism symptoms, particularly hyperactivity and social deficits. A mouse model study shows reducing excitatory to inhibitory signaling counters these issues.
SourceStanford Medicine·JournalScience Translational Medicine·DateAug 2, 2017
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Adults with autism tend to overestimate environmental changeability, reducing prior expectations' influence on behavior. This may contribute to sensory overload and social difficulties.
SourceUniversity College London·JournalNature Neuroscience·DateJul 31, 2017
Researchers at UCLA have discovered a link between brain wave frequency and nonverbal IQ in children with autism. The study found that lower peak alpha frequency corresponds to lower non-verbal IQ, suggesting a potential biomarker for detecting autism severity.
SourceUniversity of California - Los Angeles·JournalEuropean Journal of Neuroscience·DateJul 25, 2017
A new study has identified a tool to detect signs of autism in high-risk infants with TSC, a genetic disorder. The Autism Observation Scale for Infants (AOSI) was found to be a useful clinical tool in determining which infants are at increased risk of developing ASD.
SourceCincinnati Children's Hospital Medical Center·JournalPediatric Neurology·DateJul 17, 2017
A recent study using three genetic sequencing technologies found that late-breaking mutations occurring after conception are linked to autism spectrum disorder (ASD). These mutations, known as post-zygotic mutations, were discovered in a subset of cells and disproportionately affect the amygdala.
SourceBoston Children's Hospital·JournalNature Neuroscience·DateJul 17, 2017
A large study of executive function and adaptive behavior in females with autism spectrum disorders reveals unique challenges in diagnosis and intervention. The study found that girls with ASD struggle more with independence skills despite having better social and communication skills.
SourceChildren's National Hospital·JournalAutism Research·DateJul 14, 2017
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Researchers propose a potential connection between carnitine deficiency and mild forms of autism, which disproportionately affect males. They suggest that supplementing infants with carnitine could prevent up to 10-20% of cases of autism.
SourceBaylor College of Medicine·JournalBioEssays·DateJul 13, 2017
Researchers at the University of Missouri-Columbia found that diet is not a contributing factor to gastrointestinal issues in children with autism spectrum disorder. Stress, rather than nutrition, appears to be a major contributor to these symptoms.
A NIH-funded study suggests that children's visual engagement is heritable and altered in autism, with identical twins showing synchronized eye movements and reduced attention to face regions. Researchers found that genetic factors influence social behaviors, which can help identify new treatments for autism.
SourceNIH/Eunice Kennedy Shriver National Institute of Child Health and Human Development·JournalNature·DateJul 12, 2017
A new Stanford study found that oxytocin improves social behavior in children with autism who have low oxytocin levels, but not those with high levels. The study suggests that baseline oxytocin levels can predict which children will benefit from oxytocin treatment.
SourceStanford Medicine·JournalProceedings of the National Academy of Sciences·DateJul 10, 2017
Children with autism spectrum disorder may benefit from assessments for developmental coordination disorder (DCD) due to overlapping symptoms and co-occurrence. The UTA study highlights the importance of evaluating individuals with autism thoroughly for DCD, which affects up to 7% of school-age children.
SourceUniversity of Texas at Arlington·JournalResearch in Autism Spectrum Disorders·DateJun 29, 2017
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A new analysis shows that genetic variation and elevated ozone exposure increase the risk of developing autism, with an added effect when combined. The study found that copy-number variation and particulate matter in the environment had significant individual impacts on autism risk.
A recent study by UCSF researchers found that around 22.8% of children with Tourette's met the criteria for autism, compared to 8.7% of adults. The study suggests that the high rate may be due to shared symptoms rather than an overlapping etiology.
SourceUniversity of California - San Francisco·JournalJournal of the American Academy of Child & Adolescent Psychiatry·DateJun 22, 2017
A new mathematical method identifies ancient genetic variations contributing to autism spectrum disorder, suggesting a small effect of each variant. The approach uses discordant siblings to find a clear signal of these shared variants, which are common among individuals with autism in both affected and unaffected populations.
SourceCold Spring Harbor Laboratory·JournalProceedings of the National Academy of Sciences·DateJun 21, 2017
Researchers used functional connectivity magnetic resonance imaging (fcMRI) to scan 59 high-risk, 6-month-old infants, finding that brain patterns preceded behavioral symptoms of autism. The technique accurately predicted diagnoses in 82% of cases, with 93% accuracy in smaller groups.
SourceNIH/Eunice Kennedy Shriver National Institute of Child Health and Human Development·JournalScience Translational Medicine·DateJun 7, 2017
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A new study led by Giulia Righi identified key factors that put young people with autism at high risk of seeking inpatient psychiatric care. Disrupted sleep and mood disorders were found to be significant predictors, while adaptive functioning had a slightly protective effect.
SourceBrown University·JournalJournal of Autism and Developmental Disorders·DateJun 2, 2017
Researchers found higher levels of lead and lower levels of zinc and manganese in children with autism compared to those without. The study used lasers to map growth rings in baby teeth to track metal uptake during development.
SourceNIH/National Institute of Environmental Health Sciences·JournalNature Communications·DateJun 1, 2017
A large Swedish study found no link between autism and violent offending, but conditions like ADHD that co-occur with autism do. Individuals with co-occurring conditions had a higher risk of convictions for violent crimes.
SourceElsevier·JournalJournal of the American Academy of Child & Adolescent Psychiatry·DateJun 1, 2017
ECHO Autism program trains primary care providers to diagnose and manage autism spectrum disorders, improving confidence and access to care for children with autism in rural areas. The program's expansion aims to bridge gaps in healthcare for underserved communities worldwide.
SourceUniversity of Missouri-Columbia·JournalClinical Pediatrics·DateJun 1, 2017
A large study published in the Journal of the American Academy of Child and Adolescent Psychiatry found that a diagnosis of autism alone is not associated with an increased risk of violent offending. Instead, conditions like ADHD that co-occur with autism may increase this risk.
SourceUniversity of Bristol·JournalJournal of the American Academy of Child & Adolescent Psychiatry·DateMay 31, 2017
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A double-blind, placebo-controlled trial tested the 100-year-old drug suramin in boys with autism, showing significant improvements in language, social interactions, and restricted behaviors. The study's findings challenge the conventional view of autism as a fixed, genetically-driven condition and suggest a treatable metabolic syndrome.
SourceN of One: Autism Research Foundation·JournalAnnals of Clinical and Translational Neurology·DateMay 26, 2017
Suicide rates among people with autism in England have reached high levels, according to researchers from Coventry and Newcastle universities. The issue remains poorly understood, and action is urgently needed to help those most at risk.
SourceCoventry University·JournalThe Lancet Psychiatry·DateMay 24, 2017
Researchers developed an ethnically sensitive screening methodology to identify Latino infants at risk for autism spectrum disorder. The unique approach resulted in a 90% screening rate and a 4% referral rate for further testing, mirroring US English-language toddler study findings.
Stephanie Solso received the award for her paper on diffusion tensor imaging and axonal overconnectivity in autism spectrum disorder toddlers. The study revealed abnormal brain development and age-related changes in brain regions involved in social, language, and behavioral control functions.
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New studies published in JAMA Network report no increased risk of autism spectrum disorder and attention-deficit/hyperactivity disorder among children exposed to antidepressants during pregnancy. The research suggests alternative explanations for previous findings may be responsible.
Researchers found that young adults with autism struggle with financial management, leading to anxiety and frustration in adulthood. Implementing early financial management programs can empower them with essential skills.
SourceUniversity of Missouri-Columbia·JournalJournal of Child and Family Studies·DateApr 17, 2017
A new online genetic study called SPARK is enrolling thousands of people with autism and their families to identify the hundreds of autism genes at play. The study seeks to connect these individuals and families to research opportunities that advance the understanding of autism.
A new study finds that deaths in autistic individuals increased 700 percent in the past 16 years, mostly due to injuries. Swimming classes are recommended immediately after diagnosis to prevent drowning-related fatalities.
SourceColumbia University's Mailman School of Public Health·JournalAmerican Journal of Public Health·DateMar 21, 2017
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A new analysis method accurately predicts whether a child has autism by analyzing metabolic biomarkers, offering hope for earlier diagnosis. The method, developed by Rensselaer Polytechnic Institute researchers, correctly classified 97.6% of children with autism and 96.1% of neurotypical children.
SourcePLOS·JournalPLOS Computational Biology·DateMar 16, 2017
Researchers at Rensselaer Polytechnic Institute developed an algorithm that accurately predicts whether a child is on the Autism spectrum of disorder based on levels of metabolites found in a blood sample. The algorithm, which uses big data techniques, correctly identified 96.1% of neurotypical participants and 97.6% of children with ASD.
SourceRensselaer Polytechnic Institute·JournalPLOS Computational Biology·DateMar 16, 2017
Researchers identified a gene link to impaired sociability in autism and found its neural circuit mechanism. The study suggests a 'toggle switch' that can be turned on or off to regulate sociability, potentially leading to new treatments for patients with autism. Seizures were also found to impair sociability by repressing specific genes.
SourceBeth Israel Deaconess Medical Center·JournalNature·DateMar 15, 2017
The study identified 61 genetic variations that affect autism risk, including copy number variations and chromosomal abnormalities. Many of these variations were found in areas of the genome once considered 'junk DNA,' suggesting a crucial role in controlling gene activity during brain development.
SourceAutism Speaks·JournalNature Neuroscience·DateMar 6, 2017
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Researchers found that adults with autism process unrelated words similarly to those without the disorder, using distinct learning strategies. The study suggests that adults with autism use an alternative mechanism to process language, resulting in a different pattern in the brain.
SourceJohns Hopkins Medicine·JournalJournal of Autism and Developmental Disorders·DateMar 1, 2017
Researchers are studying novice drivers with autism to determine if specialized training can improve their driving skills and reduce collisions. They will use a high-tech driving simulator and on-road driving to compare the performance of drivers with and without autism.
SourceUniversity of Virginia Health System·DateMar 1, 2017
A study published in the Journal of Autism and Developmental Disorders found that adolescents with autism are four times more likely to visit the emergency department than their non-autistic peers. The research suggests that youth with autism may need better access to primary care and specialist services.
SourcePenn State·JournalJournal of Autism and Developmental Disorders·DateFeb 28, 2017
Recent immune research advances the understanding of autism spectrum disorder (ASD), highlighting the role of immune dysregulation in its development. Therapies targeting the immune system may also have benefits beyond ASD, such as preventing attention-deficit/hyperactivity disorder.
SourceElsevier·JournalBiological Psychiatry·DateFeb 21, 2017
A study published in Nature found that brain imaging biomarkers at 6 and 12 months can accurately predict which infants will develop autism spectrum disorder by 24 months. The predictive power of the findings may inform the development of a diagnostic tool for ASD, potentially intervening earlier to improve outcomes.
SourceUniversity of Washington·JournalNature·DateFeb 15, 2017
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Researchers used MRI to identify differences in brain development among high-risk infants, finding that those with autism showed faster brain growth rates between 6-12 months. These early brain changes can help predict autism diagnosis at age 2 years.
SourceNIH/Eunice Kennedy Shriver National Institute of Child Health and Human Development·JournalNature·DateFeb 15, 2017
A new study uses magnetic resonance imaging to identify infants at high risk for developing autism by age two, with over 90% accuracy. The research found that rapid growth of the brain's surface area is a key indicator of autism risk.
SourceChildren's Hospital of Philadelphia·JournalNature·DateFeb 15, 2017
A new study found significant improvements in social cognition and autistic mannerisms of young subjects after outdoor adventure activities. The research suggests a promising treatment for autism spectrum disorder, with potential benefits for children's social communication skills.
SourceAmerican Friends of Tel Aviv University·JournalDevelopmental Medicine & Child Neurology·DateFeb 15, 2017
A new study published in Research in Autism Spectrum Disorders found an inverse correlation between brain stem volume and aggression in children with autism. The researchers discovered that a smaller brain stem is associated with greater aggression, suggesting a potential target for treatment.
SourceBrigham Young University·JournalResearch in Autism Spectrum Disorders·DateFeb 9, 2017
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A study by Rosalind Franklin University of Medicine and Science identifies a specific brain circuit in the amygdala as crucial for empathy, providing hope for new treatments of social difficulties in autism. The findings suggest that targeting this region may help individuals with autism spectrum disorder develop social abilities.
SourceRosalind Franklin University of Medicine and Science·JournalNature Neuroscience·DateFeb 7, 2017
Research from Penn State College of Medicine found that Medicaid waivers improving access to home and community-based services for children with autism also support parental employment. Waiver programs with increased cost limits and enrollment limits helped lower-income households, while those with higher limits benefited higher-income...
A study by NYU's Steinhardt School found that adults with autism view their interests positively, believing they should be encouraged. These interests also alleviate anxiety in 92% of respondents and are used as strengths in career paths and educational settings.
SourceTaylor & Francis Group·JournalOccupational Therapy in Mental Health·DateFeb 2, 2017