A team of researchers at the University of Missouri has identified 286 genes associated with autism, including 193 new genes not found in previous studies. This breakthrough could lead to the development of screening tools and interventions for young children and improve diagnosis accuracy.
Researchers at the University of Warwick have developed a new test that can detect damage to proteins in blood plasma, which may indicate autism spectrum disorders. The test has shown promise in distinguishing between children with ASD and healthy controls.
Researchers at Rutgers New Jersey Medical School developed a two-minute questionnaire to detect autism in toddlers. The Psychological Development Questionnaire (PDQ-1) correctly identified children with autism spectrum disorder (ASD) from all socioeconomic communities.
Researchers at Oregon State University discovered that exposure to valproic acid, a migraine treatment, causes characteristics similar to autism spectrum disorder (ASD) in zebrafish. The study validated zebrafish as a model for studying ASD and its causes, providing a faster and more efficient alternative to traditional rodent models.
Researchers at Indiana University and Rutgers University found a correlation between subtle changes in movement and autism diagnoses, suggesting a potential biomarker for early detection. The study assessed volunteers' arm movements using high-speed sensors, revealing hidden fluctuations that corresponded to previous autism diagnoses.
A recent study has identified over 2,000 regulatory regions involved in learning that are strongly associated with autism. The research team found a genetic mutation linked to increased risk of developing autism in one of these regions, offering a promising new approach to diagnosis and treatment.
A new study finds that girls with autism often struggle more than boys with performing routine tasks and making small talk, even when standardized tests are normalized for sex. This suggests that girls with autism may be 'camouflaging' their symptoms, leading to delayed or missed diagnoses.
The new journal will publish evidence-based original articles, review articles, and analysis on various aspects of adult autism, including physical and mental health, research methodology, and policy change. The journal aims to provide authoritative insights and promote practice, systems, and policy changes for adults with ASD.
Research led by Professor Stephen Wood at Orygen found that individuals with autism traits and psychosis are at a greater risk of depression and suicidal thoughts. The study suggests that identifying autism traits can help identify those most at risk of suicide, highlighting the need for better training and assessments.
A new virtual child software is being developed to train professionals in behavioral intervention techniques for children with autism spectrum disorder. The software will feature a virtual child programmed with learning difficulties associated with autism, allowing users to practice and master treatment methods.
Researchers at Weizmann Institute of Science found that individuals on the autism spectrum exhibit distinct reactions to 'smells of fear' and 'calm sweat', including changes in anxiety levels. This suggests a possible underlying connection between smell, social cues, and early brain development in autism.
A study published in Autism Research found a correlation between shorter time intervals between pregnancies and increased risk of Autism Spectrum Disorder in second-born children. The researchers suggested that couples planning pregnancy should discuss their options with a trusted doctor or healthcare provider.
Researchers found that social and emotional exclusion in mainstream schools can lead to increased isolation and low self-esteem in pupils with autism. Creating a culture of acceptance is crucial for long-term wellbeing.
Researchers have tested a potential new drug, NitroSynapsin, in a mouse model of an autism disorder and found it largely corrected electrical, behavioral and brain abnormalities. The candidate drug is intended to restore the signaling imbalance found in virtually all forms of autism spectrum disorder.
The Azrieli Centre for Autism Research will foster innovations in therapy and a better understanding of autism spectrum disorder. Researchers will use advanced brain imaging techniques to map differences in children and adults living with ASD, leading to earlier diagnosis and effective intervention.
Researchers discovered a genetic cause of autism that affects male mice more severely than females, leading to abnormal reward-learning behavior. This study sheds light on the sex differences in autism and may lead to new treatments for the disorder.
Researchers have discovered a new genetic signature for autism by analyzing the genomes of 516 autistic children and their families. The study found that individuals with autism are more likely to have multiple genetic variations, suggesting a complex interplay between genes in the development of the disorder.
A Drexel University-led study found that multivitamin use during pregnancy may reduce the risk of autism with intellectual disabilities by 30%. The study, published in BMJ, looked at data from over a decade and controlled for other factors. However, more research is needed to clarify the relationship between diet and autism development.
Researchers have identified networks of genes related to autism spectrum disorder (ASD) that may also be involved in cancer, potentially leading to new treatment options. The study used a computational technique to account for gene interactions, revealing genes that could affect similar pathways.
The largest study to date finds a significant difference in autism recurrence risk based on sibling gender. Boys are more susceptible to autism, especially when an older female sibling has the condition. Meanwhile, female siblings with older brothers have lower risks.
Researchers found eight mutations associated with autism in the TRIO gene, which can lead to weaker or stronger connections between brain cells. Weaker connections may hinder information storage and processing, while stronger connections cause trouble communicating between brain cells.
Researchers at the A.J. Drexel Autism Institute are studying the benefits of early detection of autism through a $11.4 million grant from the National Institutes of Health. Early detection is critical for improving outcomes in social and cognitive functioning, as well as mitigating disabilities over a child's lifetime.
Researchers suggest that reversing excitation-inhibition imbalance could alleviate autism symptoms, particularly hyperactivity and social deficits. A mouse model study shows reducing excitatory to inhibitory signaling counters these issues.
Adults with autism tend to overestimate environmental changeability, reducing prior expectations' influence on behavior. This may contribute to sensory overload and social difficulties.
Researchers at UCLA have discovered a link between brain wave frequency and nonverbal IQ in children with autism. The study found that lower peak alpha frequency corresponds to lower non-verbal IQ, suggesting a potential biomarker for detecting autism severity.
A recent study using three genetic sequencing technologies found that late-breaking mutations occurring after conception are linked to autism spectrum disorder (ASD). These mutations, known as post-zygotic mutations, were discovered in a subset of cells and disproportionately affect the amygdala.
A new study has identified a tool to detect signs of autism in high-risk infants with TSC, a genetic disorder. The Autism Observation Scale for Infants (AOSI) was found to be a useful clinical tool in determining which infants are at increased risk of developing ASD.
A large study of executive function and adaptive behavior in females with autism spectrum disorders reveals unique challenges in diagnosis and intervention. The study found that girls with ASD struggle more with independence skills despite having better social and communication skills.
Researchers propose a potential connection between carnitine deficiency and mild forms of autism, which disproportionately affect males. They suggest that supplementing infants with carnitine could prevent up to 10-20% of cases of autism.
Researchers at the University of Missouri-Columbia found that diet is not a contributing factor to gastrointestinal issues in children with autism spectrum disorder. Stress, rather than nutrition, appears to be a major contributor to these symptoms.
A NIH-funded study suggests that children's visual engagement is heritable and altered in autism, with identical twins showing synchronized eye movements and reduced attention to face regions. Researchers found that genetic factors influence social behaviors, which can help identify new treatments for autism.
A new Stanford study found that oxytocin improves social behavior in children with autism who have low oxytocin levels, but not those with high levels. The study suggests that baseline oxytocin levels can predict which children will benefit from oxytocin treatment.
Children with autism spectrum disorder may benefit from assessments for developmental coordination disorder (DCD) due to overlapping symptoms and co-occurrence. The UTA study highlights the importance of evaluating individuals with autism thoroughly for DCD, which affects up to 7% of school-age children.
A new analysis shows that genetic variation and elevated ozone exposure increase the risk of developing autism, with an added effect when combined. The study found that copy-number variation and particulate matter in the environment had significant individual impacts on autism risk.
A recent study by UCSF researchers found that around 22.8% of children with Tourette's met the criteria for autism, compared to 8.7% of adults. The study suggests that the high rate may be due to shared symptoms rather than an overlapping etiology.
A new mathematical method identifies ancient genetic variations contributing to autism spectrum disorder, suggesting a small effect of each variant. The approach uses discordant siblings to find a clear signal of these shared variants, which are common among individuals with autism in both affected and unaffected populations.
Researchers used functional connectivity magnetic resonance imaging (fcMRI) to scan 59 high-risk, 6-month-old infants, finding that brain patterns preceded behavioral symptoms of autism. The technique accurately predicted diagnoses in 82% of cases, with 93% accuracy in smaller groups.
A new study led by Giulia Righi identified key factors that put young people with autism at high risk of seeking inpatient psychiatric care. Disrupted sleep and mood disorders were found to be significant predictors, while adaptive functioning had a slightly protective effect.
Researchers found higher levels of lead and lower levels of zinc and manganese in children with autism compared to those without. The study used lasers to map growth rings in baby teeth to track metal uptake during development.
ECHO Autism program trains primary care providers to diagnose and manage autism spectrum disorders, improving confidence and access to care for children with autism in rural areas. The program's expansion aims to bridge gaps in healthcare for underserved communities worldwide.
A large Swedish study found no link between autism and violent offending, but conditions like ADHD that co-occur with autism do. Individuals with co-occurring conditions had a higher risk of convictions for violent crimes.
A large study published in the Journal of the American Academy of Child and Adolescent Psychiatry found that a diagnosis of autism alone is not associated with an increased risk of violent offending. Instead, conditions like ADHD that co-occur with autism may increase this risk.
A double-blind, placebo-controlled trial tested the 100-year-old drug suramin in boys with autism, showing significant improvements in language, social interactions, and restricted behaviors. The study's findings challenge the conventional view of autism as a fixed, genetically-driven condition and suggest a treatable metabolic syndrome.
Suicide rates among people with autism in England have reached high levels, according to researchers from Coventry and Newcastle universities. The issue remains poorly understood, and action is urgently needed to help those most at risk.
Researchers developed an ethnically sensitive screening methodology to identify Latino infants at risk for autism spectrum disorder. The unique approach resulted in a 90% screening rate and a 4% referral rate for further testing, mirroring US English-language toddler study findings.
Stephanie Solso received the award for her paper on diffusion tensor imaging and axonal overconnectivity in autism spectrum disorder toddlers. The study revealed abnormal brain development and age-related changes in brain regions involved in social, language, and behavioral control functions.
New studies published in JAMA Network report no increased risk of autism spectrum disorder and attention-deficit/hyperactivity disorder among children exposed to antidepressants during pregnancy. The research suggests alternative explanations for previous findings may be responsible.
Researchers found that young adults with autism struggle with financial management, leading to anxiety and frustration in adulthood. Implementing early financial management programs can empower them with essential skills.
A new online genetic study called SPARK is enrolling thousands of people with autism and their families to identify the hundreds of autism genes at play. The study seeks to connect these individuals and families to research opportunities that advance the understanding of autism.
A new study finds that deaths in autistic individuals increased 700 percent in the past 16 years, mostly due to injuries. Swimming classes are recommended immediately after diagnosis to prevent drowning-related fatalities.
A new analysis method accurately predicts whether a child has autism by analyzing metabolic biomarkers, offering hope for earlier diagnosis. The method, developed by Rensselaer Polytechnic Institute researchers, correctly classified 97.6% of children with autism and 96.1% of neurotypical children.
Researchers at Rensselaer Polytechnic Institute developed an algorithm that accurately predicts whether a child is on the Autism spectrum of disorder based on levels of metabolites found in a blood sample. The algorithm, which uses big data techniques, correctly identified 96.1% of neurotypical participants and 97.6% of children with ASD.
Researchers identified a gene link to impaired sociability in autism and found its neural circuit mechanism. The study suggests a 'toggle switch' that can be turned on or off to regulate sociability, potentially leading to new treatments for patients with autism. Seizures were also found to impair sociability by repressing specific genes.
The study identified 61 genetic variations that affect autism risk, including copy number variations and chromosomal abnormalities. Many of these variations were found in areas of the genome once considered 'junk DNA,' suggesting a crucial role in controlling gene activity during brain development.
Researchers found that adults with autism process unrelated words similarly to those without the disorder, using distinct learning strategies. The study suggests that adults with autism use an alternative mechanism to process language, resulting in a different pattern in the brain.
Researchers are studying novice drivers with autism to determine if specialized training can improve their driving skills and reduce collisions. They will use a high-tech driving simulator and on-road driving to compare the performance of drivers with and without autism.
A study published in the Journal of Autism and Developmental Disorders found that adolescents with autism are four times more likely to visit the emergency department than their non-autistic peers. The research suggests that youth with autism may need better access to primary care and specialist services.
Recent immune research advances the understanding of autism spectrum disorder (ASD), highlighting the role of immune dysregulation in its development. Therapies targeting the immune system may also have benefits beyond ASD, such as preventing attention-deficit/hyperactivity disorder.
Researchers used MRI to identify differences in brain development among high-risk infants, finding that those with autism showed faster brain growth rates between 6-12 months. These early brain changes can help predict autism diagnosis at age 2 years.
A study published in Nature found that brain imaging biomarkers at 6 and 12 months can accurately predict which infants will develop autism spectrum disorder by 24 months. The predictive power of the findings may inform the development of a diagnostic tool for ASD, potentially intervening earlier to improve outcomes.