Articles tagged with Medical Treatments
Researchers at Karolinska Institutet study how the immune system protects against malaria, finding that people who have contracted the disease before develop a tolerance that prevents severe disease. This knowledge can aid in the development of more effective vaccines.
A new Michigan Medicine study found that for children with a pelvic tilt and lower lumbar spine tilt of fewer than 10 degrees, the pelvis did not need to be included when inserting growing rods. This could help avoid painful complications such as skin breakdown and infection.
Researchers studied two strains of Mycobacterium tuberculosis with different lung attack mechanisms, finding that high-transmission strains trigger granulomas that may aid bacterial escape into the airways. In contrast, low-transmission strains cause inflammation that traps bacteria, reducing transmissibility.
Researchers at Tokyo University of Science discovered that disulfiram inhibits FROUNT protein and chemokine signaling pathways, reducing anxiety levels in mice. The study suggests a potential breakthrough anti-anxiety medication with safe and effective treatment for elderly patients suffering from anxiety and insomnia.
A survey found that individuals experiencing food insecurity were twice as likely to delay or forego medical care due to cost concerns. Food insecurity disproportionately affected racial and ethnic minority groups, low-income individuals, and those who lost their jobs or income.
A new study by researchers at the University of Birmingham has identified two distinct brain structure patterns associated with poor outcomes in patients with recent onset psychosis and depression. The study used MRI scans to analyze grey matter volume and found that lower volumes were linked to poorer outcomes, while higher volumes we...
Current guidelines for treating women's obesity, hypertension and diabetes are based on men's studies. Researchers call for sex-specific guidelines to accurately treat these conditions in women, as they have different risk factors and manifestations.
A new study shows that the telestroke program prevents unnecessary hospital transfers for stroke patients, decreasing rural healthcare disparities. The program increases care efficiency and cost-effectiveness, while optimizing care for patients.
Researchers from Goethe University and University of Kent found aprotinin effective against SARS-CoV-2 variants, including Delta and Omicron, by preventing virus entry into host cells. A recent phase III clinical study demonstrated the treatment reduced hospital stays by five days.
A new study reveals funding for fertility preservation policies varies across the UK, with Scotland offering the most inclusive approach. The study highlights the need for standardization of policies to ensure equal access to care for patients.
A study published in the Journal of Alzheimer's Disease Reports suggests that damage to the blood-brain barrier is the determining cause of Alzheimer's disease. The Lipid Invasion Model proposes that lipids entering the brain due to barrier damage lead to brain shrinkage, amyloid plaques, and tau tangles, characteristic of the disease.
A recent UCLA study found that the injury rate for e-scooter riders in Los Angeles is higher than the national rates for motorcycle, bicycle, car, and pedestrian injuries. The study estimates 115 injuries per 1 million e-scooter rides, highlighting a growing risk as e-scooters proliferate globally.
The study found significant improvements in blood flow through the heart and quality of life at one year, with all 36 patients achieving a reduction in tricuspid regurgitation severity. Longer follow-up is needed to determine how well the device continues to perform.
A randomized clinical trial comparing FFR-guided and IVUS-guided PCI found similar outcomes for patients with intermediate coronary artery stenosis. Patients evaluated by FFR underwent fewer stents but had similar rates of adverse events and improved quality of life.
A study found that implantable heart monitors do not reduce cardiovascular events overall, but patients with non-ST segment elevation myocardial infarction (NSTEMI) heart attacks saw strong benefits. Monitoring for abnormal heart rhythms may help guide care for NSTEMI patients.
Researchers found a significant decline in in-hospital mortality and secondary endpoints for STEMI patients with COVID-19 in 2021 compared to 2020. Vaccination status showed zero hospital deaths among vaccinated patients, while unvaccinated patients experienced high death rates.
A study in rats suggests that vitamin C supplementation can help preserve skeletal muscle after doxorubicin therapy, reducing oxidative stress and inflammation. The findings suggest vitamin C may represent a promising opportunity to reduce some of the drug's most debilitating side effects.
A study presented at the American College of Cardiology's Annual Scientific Session found that personalized nutrition education in grocery stores significantly improved DASH diet adherence. Participants who received six one-on-one sessions with a dietitian showed an average increase of 4.7 points on their DASH scores.
A new study suggests that cardamonin, a compound from the cardamom spice, can kill triple-negative breast cancer cells and reduce PD-L1 expression. The findings hold promise for improving cancer therapy without severe side effects.
Researchers developed an algorithm to classify 16 distinct adult sleep patterns based on arm acceleration data from 100,000 UK Biobank participants. These patterns can be used to diagnose insomnia and develop personalized treatment methods, offering new insights into human sleep behavior.
A new collaboration between UW Oshkosh and Fauna Bio aims to translate animal disease resistance into human treatments. The partnership will enable researchers to study emerging animal models, such as the 13-lined ground squirrel, to develop novel therapeutic programs.
H. Alex Choi receives NIH grant to develop protein biomarkers for delayed cerebral ischemia, a complication after subarachnoid hemorrhage that affects approximately 50,000 Americans annually. The goal is to predict which patients will worsen and identify biological processes causing worsening patients.
Researchers at Okayama University have created a new method to kill cancer cells using light-activated protein AR3, reducing the risk of adverse reactions. The approach uses green light to trigger apoptosis in targeted cells, offering a promising alternative to conventional treatments.
A new treatment approach has been proposed for children with congenital muscle disorders, using inhibitors to improve muscle function and movement in mice with mutations in the RYR1 gene. The therapy targets genetic material overload caused by excessive enzyme production, leading to reduced access of genes to cellular machinery.
Researchers at UVA Health System discovered a cluster of cells in the brainstem that controls the body's response to severe blood loss. The study found that re-activating these neurons can restore blood pressure and heart rate in lab rats, offering new hope for treating traumatic injuries.
Researchers at Boston University have developed optoacoustic neurostimulation with single neuron and subcellular level precision. Optoacoustic neuromodulation may offer advantages over ultrasonic neuromodulation, including higher spatial temporal resolution.
A report by the British Pharmacological Society and Royal College of Physicians recommends integrating pharmacogenomic testing to ensure medicines work safely and effectively for individual patients. The UK is a world leader in genomic medicine, and expanded testing would further demonstrate this leadership.
The Experimental Biology (EB) 2022 meeting features live presentations and a moderated Q&A session on groundbreaking studies. The virtual press conference reveals potential treatments for Parkinson's disease, COVID-19 vaccine-associated side effects, and alleviating food allergies.
In an animal study, researchers created an implantable biotechnology called MASTER that produces and releases CAR-T cells for attacking cancerous tumors. This technology reduces the manufacturing time from weeks to hours, increasing efficiency and effectiveness.
Research found that IVF clinics offering money-back guarantees have a higher live-birth success rate and lower multiple birth risks compared to those without MBGs. The study suggests that these programs serve as signals of high-quality care in the field of IVF and other healthcare services.
A study found that 42% of TikTok videos on high blood pressure focused on alternative medicine, while only 5% mentioned exercise. Most creators were not healthcare professionals, highlighting the need for more emphasis on credible sources.
Researchers have identified a new family of proteins in blood vessels that prevent fluid from entering the lungs, offering a potential new avenue for treating acute respiratory distress syndrome. Stimulating these bitter taste receptors has been shown to provide protection against fluid leak into the lung.
A study found that 25.3% of children with mild head injuries continue to suffer from persistent post-concussion syndrome for years, often misdiagnosed as ADHD or sleep disorders. The syndrome causes chronic symptoms like forgetfulness, memory problems, and sensitivity to light and noise.
A recent study found that approximately 1 in 3 heart attack survivors experience significant mental decline in the days and months following their heart attack. Cognitive deficits can impact quality of life and treatment adherence, emphasizing the need for cardiologists to monitor patients regularly.
The American College of Chest Physicians journal features cutting-edge original research on various chest medicine topics, including asthma, COPD, critical care, and sleep. The March issue includes a special series on nontuberculous mycobacterial pulmonary disease, offering insights into clinical epidemiology, risk factors, and diagnosis.
Researchers found that obstructive sleep apnea (OSA) accelerates the biological aging process and causes epigenetic age acceleration, leading to increased mortality risk. However, one year of CPAP treatment significantly slows down biological age acceleration in OSA patients, suggesting a potential reversal of age-related trends.
Researchers found that four-month treatment is as effective as six months in non-severe TB cases, allowing for savings on screening and training healthcare workers. The study's results led to a change in the World Health Organisation's global guidelines, recommending a shorter treatment course for children with non-severe TB.
A study of 1,164 patients with COVID-19 found that continuing dexamethasone treatment at hospital discharge was associated with lower readmission rates and mortality within 14 days. The treatment also showed significant benefits in reducing the risk of severe disease progression.
The World Congress on Osteoporosis, Osteoarthritis & Musculoskeletal Diseases (WCO-IOF-ESCEO) 2022 will discuss secondary fracture prevention. Global experts will provide clinical guidance and information on post-fracture care through various sessions.
A team of UTSA researchers has developed an innovative inhibitor that blocks the effects of cytochrome P450 8B1, a key enzyme linked to cholesterol absorption and obesity. The treatment shows promise in reducing glucose levels without affecting body weight, offering potential relief from obesity-associated metabolic disorders.
Researchers analyzed mortality rates and complications among 5,500 COVID-19 patients treated at dedicated vs non-dedicated hospitals in Minnesota. The study found no significant difference in outcomes between the two types of hospitals.
Researchers at University of Texas at Austin create first-ever biologically authentic computer model of HIV-1 virus liposome, shedding light on replication and infectivity. The study reveals key characteristics of the liposome's asymmetry and its role in shaping macroscopic properties.
Researchers found that it took nearly three years for these drugs and biologics to be incorporated into clinical guidelines, highlighting a significant delay in patient access. The study suggests that expedited approval processes are only the first step, and planning ahead is crucial to bring needed treatments to patients.
Researchers at MIT have performed a systematic study on how different-sized polymer nanoparticles circulate in the body and interact with platelets to stop bleeding. They found that intermediate-sized particles (150 nanometers) were the most effective, with less likelihood of accumulating in off-target sites.
Researchers have made a significant breakthrough in predicting heart attacks and strokes by developing a non-invasive method using super-resolution ultrasound imaging. The technology aims to detect high-risk atherosclerotic plaques that are prone to rupture, allowing doctors to prescribe life-saving interventions.
Researchers have solved atomic-level structures of the muscle-type nicotinic acetylcholine receptor, a crucial step in understanding its function. The new findings could lead to breakthroughs in treating neurological disorders such as congenital myasthenic syndrome and myasthenia gravis.
A new study by Carnegie Mellon University found that veterans who received emergency treatment at VA hospitals had a 20% lower mortality rate compared to those treated at non-VA hospitals. The survival advantage was consistent across different patient groups, including men, women, age, and pre-existing conditions.
A new poll of people aged 50 and older found that nearly 1 in 3 had a COVID-related delay for healthcare appointments in 2021. Many unvaccinated individuals still haven't rescheduled their appointments, posing concerns about preventive care, chronic condition management, and operations.
A combined analysis of 149 studies reveals that treatment rates for major depressive disorder remain low worldwide, particularly in low and lower-middle income countries. Treatment rates are estimated to be 33% in high-income countries and just 8% in low and lower-middle income countries.
Researchers found that infusing bone-marrow stem cells into mice with sepsis increased their survival by 50-60% and decreased inflammation. This treatment could offer an alternative to current granulocyte transfusions, which have limited benefits.
A recent study by researchers from Ritsumeikan University found that athletes with a history of sprained ankle showed reduced gut bacteria diversity compared to those without such a history. This suggests that musculoskeletal injury may have a negative impact on the gut microbiota, potentially leading to long-term health consequences.
Researchers at Tokyo University of Science have developed bionanoparticles derived from corn that selectively target and inhibit the growth of cancer cells, inducing tumor necrosis factor-α release. These findings suggest a novel, economical, and safe anti-cancer therapy approach.
A new machine learning process has been developed to identify and classify hip fractures from X-rays, achieving 92% accuracy and confidence. This approach aims to improve patient outcomes, reduce care costs, and alleviate the bottleneck of unreported radiographs in the UK.
The American Heart Association has outlined five core elements to optimize the treatment of in-hospital strokes. These include education, quality review, and oversight for in-patient stroke response teams. Developing targeted quality improvement plans is crucial to reducing delays and improving outcomes for hospitalized patients.
Researchers found no clinical improvements in very elderly patients with CPAP therapy for moderate-to-severe sleep apnea. The study suggests that CPAP treatment is less effective in patients older than 80 due to a more sedentary lifestyle and other underlying disorders, limiting its long-term adherence.
Scientists have engineered baker's yeast to produce D-lysergic acid, a medication used to treat neuro-cognitive diseases. This sustainable method could potentially produce up to five tons of DLA annually, reducing the environmental impact of industrial drug production.
Researchers have discovered a streamlined two-step synthesis strategy to produce neoechinulin B and its derivatives, exhibiting strong anti-HCV and anti-SARS-CoV-2 activities. The novel process utilizes a piperazine-2,5-dione derivative and tetra-n-butylammonium fluoride (TBAF) as key reagents.
Many pragmatic trials fail to collect patient-reported data on experience, burden of disease, and quality of life. Despite this, the authors suggest that including patient-reported outcomes can provide valuable insights into patient well-being. The study urges researchers to prioritize patient-centered approaches in clinical trials.
A new genomics study has helped guide the development of vaccines against Shigella, a leading cause of severe diarrhoea in children. The research revealed the extent of genomic diversity among Shigella species, highlighting challenges to current vaccine approaches.
A plant-based diet has been shown to lower the risk of COVID-19 infection and severe illness, with some studies suggesting a 9% lower risk and 73% lower risk among healthcare workers. The 'blue zone' diet, prevalent in Okinawa, Japan, may also provide benefits.