Articles tagged with Traumatic Injury
A breakthrough in trauma care has nearly quadrupled the 'golden hour' for treating large animals with internal bleeding during emergency ground and air transport. Researchers used a closed-loop, autonomous intervention system to resuscitate pigs with traumatic injuries, extending their survival time by several hours.
Researchers at Osaka Metropolitan University have discovered that plasma irradiation can accelerate tendon repair, showing faster regeneration and increased strength in lab rats. This breakthrough could lead to shorter treatment times and more reliable tendon healing for athletes and individuals with sports-related injuries.
Scientists have found an effective treatment for spitting cobra snakebites by blocking one of the major dermonecrosis-causing toxins with varespladib. The study suggests that this repurposed drug can prevent tissue damage and may become a valuable treatment against black-necked and red spitting cobra venoms.
A recent study reveals significant racial and ethnic disparities in all-cause and cause-specific mortality among US youth. The findings highlight a disproportionate burden of mortality among American Indian or Alaska Native and Black youth, particularly those involving firearms.
A new study finds that initiating antihypertensive medication in older long-term care residents increases fracture risk, particularly among those with dementia. The study advises caution when prescribing antihypertensives to this vulnerable population.
Researchers developed a new treatment method using plasma irradiation to speed up bone healing. The study found that displaced fractures exhibited stronger unions than nonirradiated ones, with strength increased by 3.5 times.
A study found that trauma-exposed individuals with posttraumatic stress disorder (PTSD) experience swift emotional transitions between neutral and negative states. Therapeutic approaches to moderate these transitions may help alleviate PTSD symptoms. The research suggests a potential new treatment direction for this condition.
A comprehensive atlas of ageing human muscle reveals genetic and cellular processes behind muscle deterioration, including new cell populations that may explain age-related differences. The study also identifies compensatory mechanisms to counteract ageing, offering avenues for future therapies.
Researchers at Case Western Reserve, UNC/NCSU, and Pitt aim to develop an injectable nanotechnology that mimics platelet function to stabilize blood clots in traumatic injuries. The technology has the potential to stop hemorrhage and improve survival rates in emergency situations.
The US Army has cleared a new whole blood rapid test for traumatic brain injury assessment, allowing clinicians to obtain lab-quality results at the bedside in 15 minutes. This improvement enables faster decision-making and reduces unnecessary medical evacuations.
A study of 303 early childhood children found concussion associated with more postconcussive symptoms than typical development up to three months after injury. The study used developmentally appropriate manifestations and behaviors to track postconcussive symptoms and aid in concussion diagnosis in young children.
Researchers review microneedle materials, techniques and effects on wound healing in diabetic patients. They found that microneedles can enhance wound healing through various mechanisms.
Researchers analyzed trauma injury data from over 56,000 car crash victims and found that women have a higher shock index, indicating a greater risk of hemorrhagic shock. This suggests that female bodies may handle blood loss differently than male bodies, warranting further investigation into car safety design and first aid response.
Researchers have found that the PTPσ-expressing growth cone senses extracellular matrix and drives neuronal migration in injured brains, leading to functional recovery. The study also shows that growth cones can be reversed to promote neuronal migration using heparan sulfate.
The themed issue highlights advances in nosology, covert consciousness assessment, neuromedical morbidity, neurorehabilitation evaluation, and medicolegal challenges. Patients with severe brain injuries may have better prognoses than previously believed, but require careful assessment due to high misdiagnosis rates.
A study of 2,180 participants found that early childhood neighborhood poverty is significantly associated with death from unintentional injury, suicide, and homicide in early adulthood. Economic policies are needed to address health equity and premature mortality.
A recent study found that recreational marijuana laws are associated with a 10% rise in workplace injuries among individuals aged 20-34, likely due to impaired cognitive function and care. The study suggests that these laws may have unintended consequences for worker safety.
Prescription opioids linked to increased risk of serious falls among adults, with older individuals most vulnerable. Targeted prevention efforts may be most effective within the first month after opioid initiation.
A randomized clinical trial of 336 patients with extensive ischemic stroke found that endovascular thrombectomy improved clinical outcomes across a range of infarct volumes. However, the treatment's effectiveness was limited by low enrollment rates among patients with minimal penumbra volume.
A study of emergency department visits reveals that most injuries from conducted energy devices, such as TASERs, involve young Black and white males from low-income areas. This finding is consistent with existing research on police violence and racial disparities in the US population.
Researchers found that turbans greatly reduced the risk of skull fractures in areas covered with thick fabric, while different turban styles affected head injury risk. The study recommends covering larger areas with thicker fabric and reducing friction to minimize brain injuries.
A large multicenter clinical trial found that an antiseptic containing iodine resulted in about one-quarter fewer post-surgical infections in patients with limb fractures compared to another frequently used skin antiseptic. The study included nearly 8,500 patients across the US and Canada.
Participation in moderate to vigorous leisure-time physical activity was associated with lower odds of non-injurious and injurious falls among older women. Brisk walking also reduced the risk of non-injurious falls.
A study published in Brain Injury found that processing speed deficits significantly impair delayed verbal recall and overall memory in people with acquired brain injuries. Researchers recommend cognitive rehabilitation techniques to improve processing speed and enhance quality of life.
Researchers found that low-dose X-ray irradiation reduced lesion size and reversed motor deficits in TBI and ischemic stroke mice, demonstrating its potential as a therapeutic strategy. The treatment also accelerated substantial motor function recovery and promoted brain rewiring after stroke.
This study found that sports-related traumatic brain injuries (TBI) result in higher rates of functional limitations six months after injury. In contrast, patients with non-sports related TBI exhibit better mental health and post-concussion symptom recovery. The findings highlight the need for a more nuanced understanding of TBI outcomes.
Diagnostic errors in hospitalized adults who died or were transferred to the intensive care unit were common, with problems in test choice and clinician assessment identified as high-priority areas for improvement. The study analyzed 2,428 patient records at 29 hospitals and found that these errors led to significant patient harm.
Researchers developed mathematical models based on real events data from the Swedish Trauma Registry, showing that AI models outperformed clinical outcomes. The study highlights the potential of AI-powered decision support to improve ambulance staff's ability to assess injury severity and potentially save more lives.
A new study found that trauma survivors who received comprehensive mental health support after discharge had significantly lower hospital readmission rates. Researchers analyzed data from 171 patients and found that those receiving standard care had nearly twice as many readmissions as those with the intervention.
A NSF-funded project, MABLE, is developing a digital app using crowdsensing, AI, and robotics to empower individuals with responsive maps and turn-by-turn instructions. The app aims to improve accessibility and navigation for persons with visual or mobility impairments, such as those with low vision and wheelchair users.
The University of Maryland School of Medicine will collect data on trauma patients for 3.5 years to identify lifesaving advancements in medical triage. The goal is to predict the need for interventions in real-time, enabling more effective triage and improved mass casualty response efforts.
A novel mental health risk screen for hospitalized patients accurately predicts mental health outcomes, with 10 items correctly identifying 75% of those who later developed mental health issues. A tailored recovery program can also be effective in reducing mental health problems after trauma, increasing health equity among historically...
A new NIH grant will investigate how news media reports on community firearm violence affect survivors, communities, and policymakers. The research aims to develop evidence-based guidelines for safer reporting, inspired by successful approaches for other traumatic events.
Researchers at Salk Institute uncover a mechanism for repairing damaged nerves during peripheral neuropathy, with protein Mitf playing a key role. The findings have the potential to inspire novel therapeutics that bolster repair function and heal peripheral neuropathy.
New research found a 16% increase in economic burden of US firearm injuries and deaths in 2020 compared to 2019. Non-fatal costs are largely attributed to hospitalization, while fatal costs are mainly due to value of lives lost.
A unique case of commotio cordis in a Romanian basketball player highlights the condition's rarity and importance of prompt intervention. The case, validated by ECG and video evidence, underscores the need for awareness and education about this reversible cardiac phenomenon.
A randomized clinical trial of 524 trauma patients found that adding sigh breaths to mechanical ventilation did not increase ventilator-free days. However, prespecified secondary data suggest that sighs are well-tolerated and may improve clinical outcomes in this patient population.
The program, which has just one room and one laser, now has about 300 clients undergoing tattoo removal. Removing those tattoos may help individuals reduce their exposure to violence, build a new identity, and gain employment. Nearly nine out of 10 clients desired tattoo removal to transition to a healthier life.
Patients from racial and ethnic minority groups receive inadequate pain treatment in the prehospital setting, according to a study of over 4.7 million encounters across the US. The results suggest a significant disparity in pain management practices based on race and ethnicity.
Researchers found that former football players with medical and mental health conditions like depression and anxiety are at higher risk of receiving an unverified CTE diagnosis. The study highlights the need for accurate diagnoses and access to proven treatments.
A new study finds that racial and ethnic disparities in chronic pain after acute traumatic injury are driven by differences in the nature of and health care response to acute injuries. Factors associated with disparities include mechanism of injury, severity of injury, pain in the hospital, and length of hospital stay.
The Massive Transfusion in Children-II (MATIC-II) clinical trial will test multiple interventions for life-threatening bleeding in children. The trial aims to determine the most effective and safe bundle of care for pediatric trauma patients, with a focus on precision transfusion medicine.
The economic burden of youth violence in the US has reached $122 billion, driven primarily by medical care, lost productivity, and avoidable mortality from male firearm homicides. Prevention strategies can help mitigate this substantial economic burden.
A study of 805,000 patients found that receiving physical therapy after dizziness was associated with a significant reduction in fall risk over the next 12 months. The findings suggest that timely physical therapy referral for dizziness may be beneficial for these patients.
A study found large increases in cannabis-involved traffic injury emergency department visits in Ontario, Canada. The research suggests that commercialization of non-medical cannabis may have accelerated these incidents, highlighting the need for greater prevention efforts.
A large-scale study of 633,000 children found that increased pediatric readiness in emergency departments decreased overall mortality, but had little effect on racial disparities. Black children were more likely to die from acute medical emergencies compared to white children.
Researchers at Purdue University have developed a 'mini-brain' that tracks the effects of concussive force on brain cells, revealing a link between head trauma and Alzheimer's disease. The study found that even hours after a hit, acrolein production leads to misfolded amyloid beta protein aggregation.
Burn injury survivors face unique challenges, including infection, disfigurement, and disability, which can hinder their reentry into society. Researchers are using geospatial mapping techniques to identify barriers and hotspots for targeted support.
A new open-source software, NMSM Pipeline, enables clinicians and engineers to create personalized computer models of patient movement to optimize treatment designs. The software uses physics-based models to predict and optimize functional outcomes for patients with various mobility impairments.
UCSB researchers develop platform to interpret cellular 'stress memory landscape', predicting future reaction to stressors. The study opens window into various cellular stress-related conditions, including aging, cancer and neurodegenerative diseases.
Researchers from Osaka University identified ten blood proteins associated with mortality in severe burns, including HBA1, TTR, and SERPINF2. These proteins may serve as targets for developing new treatment methods for burns, offering a promising direction for future research.
Death rates due to unintentional poisonings and firearm homicides rose substantially in the US from 1999 to 2020, highlighting a pressing public health concern. The study's findings underscore the urgent need for targeted interventions to address this alarming trend.
A new device combines rapid hemorrhage management, infection control, and sensing capabilities for long-term monitoring. The device features a tunable biodegradation rate and can detect bleeding in real-time using a nanowire-based capacitive sensor.
Researchers found that obese patients with mild traumatic brain injuries had higher levels of inflammatory biomarkers and prolonged symptoms compared to those with healthy body mass indexes. The study suggests that obesity may mediate the inflammatory response and symptoms in mTBI patients.
Researchers at DTU Health Tech created a multi-levelled scaffold that enables near-perfect bone healing in just eight weeks, without using growth factors or endocrine factors and cells. The scaffold combines essential bone minerals with mechanical properties matching human bone compressive strength.
A new study examining brain tissue from 631 former football players found that the cumulative force of hits, not just the number of concussions, was the strongest predictor of chronic traumatic encephalopathy (CTE). The study suggests that reducing the force and frequency of head impacts could help prevent CTE in athletes.
Medical evacuation by train in a war zone is possible and can transport more severely ill or injured individuals due to intensive care capacity on board. The target population should not be limited to trauma patients only.
A new study found that football players' cumulative repetitive head impact exposure was associated with chronic traumatic encephalopathy (CTE) status and severity. The study suggests that reducing both the number of head impacts and their force could lower CTE risk.
Researchers at Tulane University have identified a synthetic compound called dimethyl malonate that can prevent coagulopathy during massive hemorrhages. The study found that this compound inhibits excessive cellular metabolism, preventing the glycocalyx from shedding and causing bleeding to stop.
A Eurac Research-led team tested drones' effectiveness in locating and providing first aid to injured people in difficult-to-access terrain. The study found that drone-assisted rescue operations reduced treatment time by 30% and saved critical minutes in cases of traumatic injuries and cardiac arrest.