Researchers found that girls whose mothers took paracetamol during pregnancy had smaller ovaries, fewer ovarian follicles, and lower levels of reproductive hormones at three months old. The study, published in Human Reproduction Open, suggests that foetal exposure to paracetamol may affect reproductive development, but the findings do ...
A study of 165,832 women found that later menarche is associated with an increased risk of tobacco use disorder and various conditions, including digestive issues, heart problems, and brain disorders. The researchers suggest a shift in perspective to recognize childhood influences as the primary cause of adult health problems.
Children who start puberty earlier than usual may not need the same level of testing or treatment, according to a new Endocrine Society Clinical Practice Guideline. The guideline suggests different approaches for various subgroups, including monitoring girls with slow progression and using simpler testing methods.
The ECE 2026 brings together researchers and clinicians to share the latest endocrine research and developments. Key sessions include Plenaries, Symposia, Awards, Meet the Experts, Debates, and Oral Communications.
Researchers have created a new scale to measure whether lactating mothers' psychological needs are being met, providing a tool to improve breastfeeding outcomes. The study found that when all three basic needs (autonomy, competence, and relatedness) are satisfied, exclusive breastfeeding is more likely to persist.
The European Society of Endocrinology organizes World Hormone Day to educate the public about hormone-related health issues. Global endocrine disorders affect millions worldwide, emphasizing the need for proper hormone balance.
A study published in Science reveals that microglia and the protein RANK are involved in regulating the hypothalamic-pituitary-gonadal axis, which controls fertility. The research found that suppressing RANK expression led to distorted reproductive function, including reduced sex hormones and hypogonadism.
A new Danish study compiles ten years of research identifying several factors during pregnancy and childhood that advance the timing of puberty, including genetic predisposition, maternal health, and psychosocial stressors. The study found an average shift of about three months, affecting both physical wellbeing and later health outcomes.
A new study from Aarhus University finds that early puberty is associated with an increased risk of general psychological distress, psychiatric diagnoses, and the use of psychiatric medication. Girls who enter puberty early may have twice the risk of receiving psychiatric medication for mental health conditions compared to their peers.
The European Society of Endocrinology is launching a new campaign to raise awareness about the importance of hormone health. The #BecauseHormonesMatter initiative aims to improve public understanding of hormones and promote practical steps for better hormone health, following the success of last year's campaign.
A study of over 7,600 Brazilian women found that early menarche increases risk for metabolic and heart problems, while late menarche may protect against obesity but increase certain heart issues. Understanding age at first period can help doctors identify high-risk patients and guide personalized screening and prevention efforts.
A study found that consuming aspartame, sucralose, glycyrrhizin and added sugars may increase the risk of early puberty in children, especially those with genetic traits. This association was strongest for central precocious puberty, a condition linked to emotional distress and metabolic disorders.
A new study presents preliminary data suggesting that grandparents' exposure to endocrine-disrupting chemicals may impact the age when girls get their first period. The research found that certain chemicals in both mothers and fathers were linked to earlier puberty, with stronger effects seen in granddaughters.
A new study analyzed 53 popular films and found that most depict idealized and aspirational views of puberty, romance, and relationships. This can lead to a disconnect between on-screen representations and real-life experiences, influencing how teens perceive themselves and their place in the world.
Gonadotroph cells controlling puberty and reproduction originate from two separate populations, with the majority produced after birth. This finding could aid in understanding and treating disorders impacting puberty and fertility.
Girls who enter puberty early have a higher BMI before, during, and after puberty, increasing the risk of overweight later in life. The study found that biological differences between sexes make girls more vulnerable to this impact.
A new study has discovered a link between delayed puberty and an increased risk of developing type 2 diabetes in boys. According to the research, adolescent boys who experience delayed puberty are 37% more likely to develop type 2 diabetes in early adulthood, regardless of their weight or socio-economic status.
Research suggests that antibiotics taken during infancy, especially in the first three months, may lead to earlier onset of puberty in girls. The study, which analyzed data on over 322,000 children in South Korea, found a significant association between early antibiotic exposure and increased risk of central precocious puberty.
Research found that early-life growth plays a significant role in determining final adult height, accounting for about 67% of the variation. Childhood growth also accounted for a substantial proportion of the difference in adult height.
A study published in Human Reproduction found that healthy childhood diets are associated with delayed onset of menstruation, independent of body mass index (BMI) or height. The research suggests that a diet high in fruits, vegetables, and whole grains may help reduce the risk of chronic diseases such as diabetes and breast cancer.
A national poll suggests parents are evenly split on when to start talking about puberty, with some fearing embarrassment or saying the wrong thing. Parents' own experiences may influence their approach, with many having had limited discussions themselves.
Researchers have found that puberty triggers significant changes in brain connectivity patterns in individuals with a rare genetic disorder tied to autism. The study suggests that synaptic dysfunction during development may contribute to the condition's behavioral challenges.
Researchers at McGill University found that a protein produced in muscles helps manage the release of follicle-stimulating hormone (FSH), which promotes egg maturation. Lowering myostatin levels delayed puberty and reduced fertility, while restoring it boosted FSH levels.
A randomized controlled study among NYC girls found that reading a book on puberty can lead to increased knowledge and positive attitudes towards physical activity during periods. The study, published in BMC Public Health, suggests that targeted puberty education can have significant impacts on young girls' health outcomes.
The European Society of Endocrinology (ESE) and ESE Foundation will host the first-ever World Hormone Day on April 24, 2025. The campaign aims to raise public awareness of good hormone health and improve national political engagement for better prevention, diagnosis, and treatment of endocrine disease.
Researchers discovered a single gene, vgll3, regulating thousands of genes in salmon sexual maturation, influencing traits like reproductive cell development and growth patterns. This study sheds light on how genetic variation can impact complex traits like puberty onset and has significant implications for managing wild populations.
New research reveals that hormone therapy can alter skeletal size and shape in transgender individuals who previously suppressed puberty. Transgender men treated with puberty blockers and hormone therapy have broader shoulders and a smaller pelvic inlet, while women have a larger pelvis after treatment from early puberty.
Research found that prolonged blue light exposure accelerates bone growth and bone age, leading to early puberty in rats. This could have implications for children's height and skeletal development in adulthood.
A nationwide study found that Swedish young men with delayed puberty are more likely to use healthcare services later in life. They were also more likely to be admitted to hospital and prescribed medications, indicating potential long-term health consequences.
Researchers found that female sex hormones may increase susceptibility to kidney injury during puberty, contradicting the protective effects seen in adulthood. The study suggests that developmental changes driven by the hormonal surge in puberty may override the benefits of female sex hormones later in life.
A study of 793 girls found significant variation in height growth after their first period, with most not reaching the expected 6-8 cm. Early onset of menstruation is linked to greater growth, while late onset is associated with shorter final height. Childhood BMI also plays a role in determining menarche age and subsequent growth.
Researchers analyzed ancient human bones to assess puberty stages in 13 Ice Age teens, ages 10-20. Most entered puberty at 13.5 and reached adulthood between 17-22 years old.
Research suggests that exposure to musk ambrette and cholinergic agonists can trigger early female puberty by activating key hormone receptors. This study highlights the importance of regulating personal care products and environmental chemicals to mitigate potential health risks.
A Danish study reveals that only children and those with half- or step-siblings enter puberty significantly earlier than children with biological siblings. The study found a two-month difference in girls' pubertal timing and a smaller but still significant gap for boys.
Research from the University of Bergen found that boys with higher per- and polyfluoroalkyl substances (PFAS) levels have smaller testicular volume and lower testosterone levels compared to their peers. PFAS exposure is a significant concern for pubertal development, highlighting the need for further research into its mechanisms.
The risk of developing type 1 diabetes (T1D) decreases in girls after age 10, while the risk in boys remains stable. Males with a single autoantibody have a significantly higher risk of T1D than their female counterparts.
A new study found that adolescent boys respond aggressively when they believe their masculinity is under threat, particularly in environments with rigid, stereotypical gender norms. The researchers suggest challenging restrictive norms and social pressure to prevent the development of 'fragile' masculinities.
A large-scale genetic study has found a significant link between the age of puberty in girls and weight gain, highlighting potential risks for early puberty and obesity. The study identified over 1,000 genetic variants that influence the age of first menstrual period, with around 600 being observed for the first time.
A new study from the University of South Australia explores female experiences with pelvic pain and identifies key concepts for effective pain management. The study found that women value learning about the biological explanation for persistent pain, which can help change outcomes and reduce stigma.
A study published in PLOS ONE found that earlier puberty onset is associated with higher adult cardiometabolic risk and mediates the effects of childhood risk factors. The research suggests targeting puberty onset may improve health outcomes in at-risk girls.
A 15-year longitudinal study by UCLA researchers identifies an association between prenatal stress and early signs of adrenal puberty in first-born daughters. This finding adds to the understanding of fetal programming and its impact on child development.
A new study from the University of Illinois finds that high-striving minority youth in early adolescence may experience accelerated puberty development, a potential indicator of 'skin-deep resilience,' which can lead to physiological changes such as inflammation and metabolic disorders.
New research from University of Illinois Chicago identifies a potential 'stop growing' switch triggered by steroid hormone ecdysone in fruit flies, which may relate to human puberty. The study's findings have implications for understanding the growth-stopping process in humans, particularly given recent changes in puberty onset.
Weight gain in females with a family history of mood disorders begins before the onset of mood disorders, highlighting the need for childhood interventions. Early interventions can prevent adverse mental and physical outcomes in this vulnerable group.
A University of Cincinnati study found that exposure to PFAS may delay the onset of puberty in girls by an average of five or six months. The researchers also discovered decreased hormone levels consistent with the delay, raising concerns about negative long-term health outcomes such as breast cancer and renal disease.
A USC Stem Cell-led mouse study reveals that lowering testosterone can improve the resilience of male kidneys by reducing their vulnerability to disease. The researchers also found that three months of calorie restriction has a similar effect, suggesting new potential treatments for kidney diseases.
A new study reveals that boys who smoke in their early teens may damage the genes of their future children, leading to increased risks of developing asthma, obesity, and low lung function. Researchers investigated epigenetic profiles of 875 people aged 7-50 and found changes associated with fathers' teenage smoking.
A new study found an increase in precocious puberty diagnoses among girls during the COVID-19 pandemic due to poor lifestyle changes. Girls with higher body mass index scores were more likely to be diagnosed with early puberty, suggesting a link between rapid weight gain and advanced pubertal development.
The age of individuals with gender dysphoria has decreased, especially among those assigned female at birth, according to research published in General Psychiatry. The estimated prevalence of gender dysphoria rose significantly between 2017 and 2021, while the average age of diagnosis fell from 31 to 26.
A mouse study suggests that a specific brain receptor, the leptin receptor, may be involved in the development of PCOS symptoms. Researchers found that mice exposed to excess androgens prenatally had improved estrous cycles and regulation of their menstrual cycles, offering potential therapeutic targets for people with PCOS.
A University of Gothenburg study of over 37,000 men found that being overweight in childhood and young adulthood significantly increases the risk of venous blood clots later in life. The study also suggests that overweight in puberty has a marked impact on future risks of venous thrombi.
A new study from Imperial College London finds that earlier first birth, higher number of live births, and starting periods at a younger age increase the risk of cardiovascular problems in women. The researchers hope their findings will help doctors better understand and monitor women's risk factors.
The number of US minors receiving hormone treatment and surgeries has risen significantly, despite concerns over the lack of strong evidence. Experts are questioning the evidence underpinning guidelines from organizations such as WPATH and the Endocrine Society.
Research from the University of Ottawa finds that oral contraceptives' effects on brain and mood in women may be linked to age of onset and gut microbiome. The study suggests adolescence as a critical period for understanding OCs' impact, as it influences brain development and hormonal changes.
A randomized clinical trial of 8,800 school-age children with high vitamin D deficiency showed no impact on growth or pubertal development after 3 years of weekly oral vitamin D administration. Vitamin D deficiency is associated with stunting and obesity in children.
A new study from Aarhus University found that children expressing a desire to be the opposite gender at age 11 enter puberty around two months earlier than peers. This correlation highlights the importance of awareness among healthcare professionals about previous puberty development.
Research reveals TBX3 as a fate determinant controlling hypothalamic KNDy neuron development and puberty onset. Multiple TBX3 mutants fail to form phase-separated condensates, leading to delayed puberty in UMS patients.
Research reveals early life adversity shapes brain circuits and behavior, increasing risk of depression and anxiety. Studies using rodent models uncover specific neural pathways impacted by early stress, shedding light on sex-specific responses.
Researchers at UVA Children's will use a sophisticated computer model to better understand and treat Crohn's disease, which can have lifelong consequences for young patients. The team hopes to identify biological markers or metabolic signatures that can be used for early diagnosis and personalized medicine.
A study of over 700 adolescents who underwent puberty suppression and then started gender-affirming hormone treatment found that 98% continued use. The findings contradict recent concerns about regret and support the long-term benefits of hormone therapy for young people with gender dysphoria.