Articles tagged with Bioluminescence
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Researchers at Brown University have created a bioluminescence tool that enables the measurement of activity in living brain cells without damaging them. The CaBLAM tool uses bioluminescent light production to capture single-cell and subcellular activity at high speeds, allowing for longer recordings and reducing hardware requirements.
A study led by Brazilian researchers has reconstructed the brain environment in the lab, revealing live interactions between cancer and healthy tissue. The 3D model allows real-time observation of brain metastases and has potential to reshape future therapies against metastatic melanoma.
Researchers have created glow-in-the-dark succulents using light-emitting compounds that absorb and release light slowly. The plants can shine in various colors and stay lit for up to two hours after exposure to sunlight or indoor LED light.
A new database of 400 years of sightings compiled by researchers at Colorado State University may help anticipate when and where milky seas will occur. The archive includes eyewitness reports, satellite data, and individual accounts submitted to the Marine Observer Journal.
Researchers developed a biosensor using an Amydetes vivianii firefly enzyme that detects pH changes in mammalian cells, which could be used to study diseases and assess drug toxicity. The technique is non-toxic and stable, providing a stronger glow than previous luciferases.
Researchers studied the organs producing light in Vinciguerria mabahiss, finding they use photophores as counter illumination to break up silhouette and camouflage from predators. The fish produces blue light through a bacterial reaction, using reflective cells and a lens to direct it.
The researchers have developed a groundbreaking method to expand the color palette of bioluminescent protein to 20 distinct colors, enabling advanced simultaneous multi-color imaging. This innovation makes it significantly easier and more cost-effective to monitor multiple targets or track individual cells within a population.
A novel nanobody-based immunosensor has been developed for quantitative point-of-care testing, including therapeutic drug monitoring and environmental applications. The design uses BRET—bioluminescence resonance energy transfer—and exhibits great potential in undiluted biological fluids.
A new study shows targeted delivery of energy-disrupting gene therapy using nanoparticles shrinks glioblastoma brain tumors and aggressive breast cancer tumors in mice. The technology, mLumiOpto, induces light-activated electrical currents inside cells to disrupt mitochondria, leading to programmed cell death and DNA damage.
Researchers at the University of Ottawa have developed a nanoparticle strategy to deliver both mRNA and siRNA, enhancing and interfering with multiple gene and protein expressions. This approach holds significant promise for treating major diseases like cancer and cardiovascular diseases.
Scientists at the Swiss Federal Laboratories for Materials Science and Technology have successfully created luminous wood by combining fungal threads with hardwood. The process involves a two-stage enzymatic reaction that stimulates the production of luciferin, emitting green light from the treated wood.
Researchers at MBARI discovered a remarkable new species of sea slug, Bathydevius caudactylus, that swims through the ocean's midnight zone. The creature has unique adaptations for life in this environment, including bioluminescence and a cavernous hood to trap prey.
Scientists have designed bioluminescent proteins that can produce multiple colors of light for real-time imaging in cellular and animal models. These proteins are small, efficient, highly stable and can be used for non-invasive bioimaging, diagnostics, drug discovery and more.
University of Rochester researchers have refined a noninvasive method called BL-OG that harnesses light to activate neurons in the brain. The technique has the potential to transform invasive procedures used to treat Parkinson's disease and other neurological conditions by providing a safer, less invasive alternative.
Researchers found that an orb-weaving spider manipulates the flashing signals of male fireflies to mimic female signals, luring more males into its web. The study suggests that animals can use indirect signaling to target specific prey in nature.
Researchers at Boston College found male dragonfish have evolved larger eyes to detect females who produce less light, closing a bioluminescent detection gap. This is the second known case of sexually dimorphic eye-size in fishes and highlights the unique adaptations of deep-sea species.
A genomic analysis overturned the leading hypothesis on firefly light origin, revealing that lucibufagins, a toxic compound, evolved after bioluminescence development. Fireflies' ancestors diversified during a period of rising atmospheric oxygen levels, suggesting a similar path to glowing millipedes.
A team of visionaries at the Carney Institute developed 3D-printed brain and spinal cord implants, revolutionizing surgical implantations and optical access. Bioluminescence imaging overcomes limitations of traditional fluorescent microscopy, providing unprecedented observation of neural and vascular activity.
MIT engineers create technique to image bioluminescent molecules in deep tissue with high resolution, enabling detailed studies of brain cell development and communication. The method uses engineered blood vessels that dilate in response to light, allowing researchers to pinpoint the source of light.
A recent study by the Smithsonian has pushed back the earliest dated origin of bioluminescence in animals by nearly 300 million years, dating it to around 540 million years ago in marine invertebrates called octocorals. The ability to produce light is involved in various behaviors such as camouflage, courtship, and hunting.
A team of researchers has identified coral as the oldest bioluminescent organism, with a history spanning over 540 million years. This discovery sheds new light on the evolution of organisms and their interactions with other species during the Cambrian era.
A Mediterranean marine worm has evolved massive eyes, rivaling those of mammals, to see in the dark. The worms use their exceptional vision to detect bioluminescent signals and may have a secret language through light communication.
A new bioluminescence imaging technique allows for real-time monitoring of oxygen concentration in the brain, revealing previously undetected areas of temporary hypoxia. The method enables researchers to study diseases associated with hypoxia, such as Alzheimer's and vascular dementia.
Researchers have discovered plant enzymes capable of performing complex bioluminescence reactions, enabling the creation of self-sustained light displays. This breakthrough technology has the potential to monitor disease progression and assist in drug screening, offering a non-invasive tool for understanding plant molecular physiology.
Recent discoveries enable researchers to efficiently harness the glow of bioluminescent plants using a native plant gene. The compact gene acts as a bridge between plant metabolism and light production, allowing for a constantly changing spectacle of natural light.
A Brazilian researcher led a team that described a rare medusa, Santjordia pagesi, discovered at a depth of 812 meters in the Sumisu Caldera. The species has a unique bright red stomach and may possess an arsenal of venoms unlike those discovered to date.
Scientists have created genetically modified bioluminescent petunias that emit an ethereal glow, making them up to 100 times brighter than previous plants. The new research builds on earlier discoveries and shows the genetic modifications also elevate luminescence in yeast and mammalian cells.
Researchers have developed a rapid COVID-19 test inspired by bioluminescence, detecting SARS-CoV-2 protein with the same accuracy as current techniques but in just one minute. The test uses a molecule from crustaceans to produce light when interacting with the virus's spike protein.
A recent study found a significant decline in bioluminescent beetle diversity in the Brazilian savanna over the past three decades. The researchers recorded 51 species, mostly fireflies, click beetles, and glow worms, which have declined sharply due to agricultural expansion and artificial lighting.
Researchers discovered that male ostracods create distinct patterns of bioluminescence to attract females, which are then mirrored by other males, creating a spectacular underwater display. The synchronized swim occurs after sunset at nautical twilight and is used to entice groups of females.
A team of researchers developed soft yet durable materials that glow in response to mechanical stress, using single-celled algae and a seaweed-based polymer. The materials demonstrate inherent simplicity, no electronics needed, and can be used as mechanical sensors or soft robotics, while also being resilient and self-sustaining.
Researchers at Penn State discovered that bioluminescent bacteria use a small RNA molecule called Qrr1 to coordinate their behavior and colonize the squid's light organ. This mechanism is likely widespread among bacteria, enabling them to exploit quorum sensing pathways.
Researchers at Nagoya University discovered three new species of bioluminescent polycirrus worms emitting blue-violet light, with names inspired by yokai from Japanese folklore. The findings aim to deepen understanding of bioluminescence mechanisms and potentially lead to new life sciences technologies.
The devices, made from a combination of stretchy material and dinoflagellate-infused culture solution, trigger light emission through mechanical stress. They can be recharged with sunlight and are maintenance-free, making them suitable for soft robots exploring dark environments.
A CSU researcher has obtained photographic evidence of milky seas observed from both the Earth's surface and space at the same time. The observations were made possible by a private yacht's encounter with the rare phenomenon off the coast of Java, providing new insights into its formation.
Researchers at the Beckman Institute found a direct link between high-fat diets and heightened nitric oxide levels, which can lead to increased risk of inflammation and cancer development. The study used a molecular probe to visualize changes in the tumor microenvironment.
Researchers at the University of Houston have developed a novel technology to monitor membrane protein trafficking in real-time using bioluminescence. This allows for the study of cellular processes and drug development for heart disease, metabolic disorders, cancer, infectious diseases, COVID-19, and others.
Researchers found that Arctic krill respond to visual changes during the Arctic polar night by swimming up or down in search of food and avoiding predators. The study revealed that even small changes in light intensity can entrain the biological rhythms of krill, helping them navigate their environment.
A portable, non-invasive bioluminescence imaging device has been developed to monitor biological processes in animals and humans. The technology uses a biochemical reaction between an enzyme and oxygen to produce light, allowing for minimally invasive diagnostics and potentially reducing the need for expensive tests.
Researchers at UFSCar in Brazil have developed a novel luciferin-luciferase system that produces far red light at 650 nanometers, three times brighter than natural luciferin and luciferase. This system has better thermal stability, cell membrane penetrability, and more lasting continuous bioluminescence.
New research reveals that artificial light at night significantly suppresses courtship activity in fireflies, with bright amber light having the greatest impact on female receptivity. This study highlights the need to minimize outdoor lighting to protect firefly populations.
Researchers have identified a small molecule produced by bioluminescent bacteria that plays a key role in establishing the symbiosis between the squid and its light organ. The molecule, cHP-3, is produced during colonization and influences bacterial luminescence, suggesting an important chemical signal specific to this symbiosis.
A team of NYUAD researchers has conducted a comprehensive review of bioluminescence in beetles, including fireflies, identifying structural factors that govern light emission colors. This study may lead to the development of new bioanalytical tools for early disease diagnosis and cancer treatment.
A newly discovered gene in pyrosomes, an underwater colony of tiny animals, is believed to produce the organism's bioluminescence. The gene matches one used in biotechnology and has been found in other organisms that also glow.
Florida Atlantic University has secured a four-year contract to develop a compact, high-intake bathyphotometer sensor for natural oceanic bioluminescence assessments. The project aims to better understand bioluminescence dynamics in the ocean and protect coastal regions.
Research reveals that deep-diving southern elephant seals exploit the bioluminescent flashes of squid and fish to locate prey. The flashes serve as a warning signal for the prey, allowing them to distract potential predators and escape.
Researchers have successfully created plants that produce their own visible luminescence through the insertion of DNA from mushrooms. The plants glow brightly and continuously throughout their lifecycle, offering a sustainable alternative to traditional lighting sources.
Firefly beetles are threatened by habitat loss and artificial light, with pesticides posing additional problems. The authors propose four primary goals to improve firefly prospects: preserving suitable habitats, controlling light pollution, reducing insecticide use, and developing sustainable tourism guidelines.
Brazilian researchers have discovered a new species of fungus gnat that emits blue light, which is the first record of such a species in the Neotropics. The larvae produce three lanterns and emit blue light, while adult insects do not.
A team of researchers has discovered the molecular basis of fireworms' bioluminescence, revealing a novel chemical structure for luciferin. The findings provide insight into a completely new mechanism of light emission and hold potential for developing new bioluminescence-based applications.
Researchers observe thousands of flashlight fish synchronizing their movement and facilitating schooling behavior in complete darkness. This study reveals a novel function for bioluminescence in the ocean, showing that fishes can school using only their natural light, without relying on ambient light.
The study found that less than 5% of schooling fish needed to be flashing to maintain the group in dark conditions. Flashing may serve as a predator-avoidance strategy, with some fish flashing then rapidly changing direction before flashing again.
Scientists discover new subfamily of bioluminescent click beetles in Asia, with unique characteristics and multiple origins of bioluminescence. The discovery sheds new light on the evolution and geographic distribution of these insects.
Researchers found that bioluminescence helps dinoflagellates ward off copepod grazers, allowing them to survive longer and compete better. This defense mechanism may be crucial for the species' success as a poor competitor.
Researchers have developed a new technique called BiGluc, which enables the visualization of glucose metabolism in real-time in cancerous tumors. This non-invasive imaging method could lead to more effective cancer treatments by identifying the metabolic requirements of different tumors.
Researchers found that deep-sea fish have expanded rhodopsin genes to detect bioluminescent signals, giving them an evolutionary advantage. The silver spinyfin has the most photopigment genes of any vertebrate, allowing it to detect specific wavelengths of light produced by bioluminescent organisms.
Researchers discovered a previously undescribed visual system in deep-sea fish, which uses multiple rod opsin photopigments to detect bioluminescence and potentially recognize predators or prey. This finding expands our understanding of how these organisms adapt to the dark environment of the deep sea.
Researchers developed a biosensor enhanced with gold nanoparticles for express diagnostics of stress and toxicological pollution. The sensor can detect heavy metals and monitor biomarkers like heat shock proteins 90 to indicate stress and cancer. This breakthrough improves bioluminescent analysis sensitivity.
Scientists have identified the biochemical pathway that allows bioluminescent fungi to light up and created an artificially luminescent eukaryote by inserting the necessary genes into a non-glowing yeast. The discovery could lead to widespread applications, including glowing plants and animals.
Researchers fully described the mechanism of fungal luminescence, utilizing four key enzymes to produce light. They also created an entirely new molecular instrument for biotechnology by engineering a yeast strain that glows in the dark.