Researchers at Johns Hopkins Medicine have discovered that manipulating certain nerve cells may trigger the formation of new heart muscle cells, restoring heart function after heart attacks. The study found that removing specific genes associated with circadian rhythms increased neonatal heart size and cardiomyocyte numbers by up to 10%.
SourceJohns Hopkins Medicine·JournalScience Advances·DateDec 2, 2021
Researchers at the Max Delbrück Center have developed a therapeutic agent to improve treatment of heart failure with preserved ejection fraction. The new approach targets alternative splicing in cardiac disease, using antisense oligonucleotides to stabilize sensitive molecules and trigger desired response.
SourceMax Delbrück Center for Molecular Medicine in the Helmholtz Association·JournalScience Translational Medicine·TypeExperimental study·DateDec 1, 2021
Apple iPhone 17 Pro
Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.
Research found that individuals with chronic obstructive pulmonary disease (COPD) experience cardiac autonomic dysfunction, which is improved by regular vigorous physical activity. The study assessed participants' ability to increase heart rate during exercise and recover afterwards, finding a relationship between vigorous physical act...
SourceBarcelona Institute for Global Health (ISGlobal)·JournalAnnals of Physical and Rehabilitation Medicine·TypeExperimental study·DateNov 29, 2021
Researchers at the University of Notre Dame have identified a new type of cell in the heart that may play a crucial role in regulating heart rate. The cells, termed nexus glia, resemble astrocytes found in the brain and are located in the outflow tract of the heart, where many congenital heart defects occur.
SourceUniversity of Notre Dame·JournalPLOS Biology·DateNov 18, 2021
A new study reveals that glial cells in the heart play a critical role in regulating heart rate and rhythm, as well as driving its development in the embryo. The discovery suggests that glia may also be important in other organs.
SourcePLOS·JournalPLOS Biology·TypeExperimental study·DateNov 18, 2021
Researchers found that slow release of TT-10 from nanoparticles improved heart function after a heart attack, accompanied by increased cardiomyocyte proliferation and smaller infarct size. The study suggests that PLGA nanoparticles could be used to improve treatment administration efficiency for cardiovascular drugs.
SourceUniversity of Alabama at Birmingham·JournalJCI Insight·TypeExperimental study·DateOct 22, 2021
Scientists at Lewis Katz School of Medicine discovered that reintroducing the protein LIN28 into adult heart stem cells improves their chances of survival. This breakthrough could lead to new treatments for heart disease using stem cell therapy.
SourceTemple University Health System·JournalRedox Biology·DateOct 21, 2021
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Fluke 87V Industrial Digital Multimeter is a trusted meter for precise measurements during instrument integration, repairs, and field diagnostics.
Researchers have found that heart cells regulate their circadian rhythms through changes in sodium and potassium ion levels, which can impact heart rate. This new understanding may lead to better treatments and preventative measures for combating heart conditions.
SourceUK Research and Innovation·JournalNature Communications·TypeExperimental study·DateOct 15, 2021
Left atrium emptying fraction derived from cardiac CTA improves predictive performance of established clinical risk scores. A reduced LAEF independently predicts all-cause mortality within 24 months post-procedure.
SourceAmerican Roentgen Ray Society·JournalAmerican Journal of Roentgenology·TypeObservational study·DateOct 13, 2021
Researchers developed a new system to measure and stimulate the entire ventricular surface of mouse hearts, allowing for simultaneous optical and electrical tracking of heart activity. The POEMS system provides accurate measurements of action potential propagation with minimal differences between modalities.
SourceUniversity of Bern·JournalNature Communications·TypeExperimental study·DateOct 5, 2021
Researchers developed a low-cost sensor that can diagnose heart attacks in minutes by targeting miRNA, distinguishing between acute heart attacks and reperfusion injuries. The technology addresses an unmet clinical need, offering improved diagnosis efficiency and cost-effectiveness.
SourceUniversity of Notre Dame·JournalLab on a Chip·DateOct 1, 2021
A study published in Blood Advances found that hydroxyurea therapy can improve or even reverse cardiac complications in individuals living with sickle cell anemia. The longer duration of treatment was associated with better cardiac outcomes, suggesting the need for early screening and treatment initiation for this patient population.
SourceAmerican Society of Hematology·JournalBlood Advances·DateSep 16, 2021
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Researchers discover that sudden cardiac episodes are caused by a combination of genetic mutations and chemical modifications in heart cells. The study uses new technology to manipulate the protein, demonstrating that phosphorylation can affect its function, particularly when paired with mutations.
SourceUniversity of Copenhagen - The Faculty of Health and Medical Sciences·JournalProceedings of the National Academy of Sciences·TypeExperimental study·DateSep 2, 2021
A new study found that 44% of micro-arteries from patients had abnormal myogenic tone, associated with excessive caldesmon presence and poor cell alignment. This abnormality affects blood supply within the heart and other organs, impacting quality of life and life expectancy.
SourceUniversity of Bristol·JournalCardiovascular Research·TypeObservational study·DateAug 9, 2021
The new device measures cardiac micropotential energies in real-time, allowing early detection of abnormal heart function. It has shown sensitivity and potential to prevent sudden cardiac death, with successful tracking of a volunteer's heart function over four years.
SourceTomsk Polytechnic University·JournalMeasurement·DateMay 20, 2021
A new hyperinvasive care approach improved six-month survival rates for patients with refractory out-of-hospital cardiac arrest, especially those resuscitated for over 45 minutes. The study showed better neurological function recovery in the hyperinvasive group at 30 days.
SourceAmerican College of Cardiology·DateMay 17, 2021
A new clinical trial found that a tailored, earlier heart failure rehabilitation program improved frailty, depression, and overall quality of life in hospitalized patients. The study showed significant gains in physical functioning and self-perception of health status.
SourceNIH/National Institute on Aging·JournalNew England Journal of Medicine·DateMay 16, 2021
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Celestron NexStar 8SE Computerized Telescope combines portable Schmidt-Cassegrain optics with GoTo pointing for outreach nights and field campaigns.
Researchers created synthetic hearts using statistical shape analysis to identify how heart shape relates to function. The study included 1000 new synthetic hearts made open access for testing and analysis.
SourceKing's College London·JournalPLOS Computational Biology·DateApr 15, 2021
A plant-based diet, such as the Mediterranean Diet (MIND), was found to slow down heart failure and lower the risk of cognitive decline and dementia. The study of 2,512 participants showed that a diet rich in berries and green leafy vegetables can positively impact cardiac function.
SourceBoston University School of Medicine·JournalBritish Journal Of Nutrition·DateFeb 25, 2021
A new clinical trial shows that a more sensitive test can detect heart function issues early, reducing the risk of heart failure in cancer patients. The test, which measures Global Longitudinal Strain (GLS), detected heart damage earlier and reduced cardiotoxicity in patients.
SourceUniversity Health Network·JournalJournal of the American College of Cardiology·DateFeb 2, 2021
Researchers have developed a safe and efficient stem cell therapy to regenerate cardiac function in pediatric patients with dilated cardiomyopathy. The therapy, using cardio sphere-derived cells, has shown promising results in small human trials, reversing damage and improving heart function.
SourceOkayama University·JournalScience Translational Medicine·DateJan 12, 2021
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Apple iPad Pro 11-inch (M4) runs demanding GIS, imaging, and annotation workflows on the go for surveys, briefings, and lab notebooks.
A genetic mutation in the cystic fibrosis gene may accelerate heart function decline in DMD patients, suggesting a potential benefit from more aggressive and earlier cardiac interventions. Researchers identified this specific mutation as exacerbating cardiomyopathy in DMD patients.
SourceUT Southwestern Medical Center·JournalJournal of the American Heart Association·DateNov 4, 2020
The study data show that Procizumab promptly restored cardiac dysfunction in a preclinical sepsis model by inhibiting the cardiac depressant factor DPP3. The administration of Procizumab improved heart function by increasing cardiac output, stroke volume, and left ventricular shortening fraction.
Source4TEEN4 Pharmaceuticals GmbH·JournalPLOS ONE·DateSep 16, 2020
Research found occupational exposures to pollutants, including burning wood and vehicle exhaust, were associated with abnormal heart function and structure. Long-term exposure to these pollutants may increase the risk of cardiovascular disease, especially among low-income occupations.
SourceAmerican Heart Association·DateAug 26, 2020
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Kestrel 3000 Pocket Weather Meter measures wind, temperature, and humidity in real time for site assessments, aviation checks, and safety briefings.
A clinical trial by Newcastle University found that levothyroxine does not improve cardiac function in patients who have had a heart attack and are suffering from mild or subclinical hypothyroidism. The treatment, which is commonly recommended for these patients, may actually be of no benefit.
SourceNewcastle University·JournalJAMA·DateJul 21, 2020
A recent study from Iowa State University has uncovered a link between liver and heart disease, with researchers finding that liver dysfunction can contribute to the deterioration of the heart. The study, published in Nature Communications, focuses on the role of peroxisomes in regulating lipid metabolic processes and detoxification.
SourceIowa State University·JournalNature Communications·DateJun 10, 2020
A study at Bar-Ilan University found that group drumming fosters both behavioral and physiological synchronization among participants. This synchronization enhances cohesion, predicts a heightened sense of group bonding, and even improves performance in subsequent group tasks.
SourceBar-Ilan University·JournalScientific Reports·DateMay 21, 2020
AmScope B120C-5M Compound Microscope
AmScope B120C-5M Compound Microscope supports teaching labs and QA checks with LED illumination, mechanical stage, and included 5MP camera.
Researchers found a significant association between coronary artery calcium and changes in the left ventricular mass index and aortic root diameter. This suggests that higher calcium scores may be linked to potential adverse effects on heart function, emphasizing the need for a healthy lifestyle to prevent calcification of arteries.
SourceBoston University School of Medicine·JournalPLOS ONE·DateMay 15, 2020
A world-first study led by Monash University demonstrates significant benefits to premature babies' heart and brain function when held by parents in skin-to-skin contact. One hour a day of kangaroo care significantly improved blood flow to the brain and cardiac function, compared to measurements done while in the incubator.
SourceMonash University·JournalThe Journal of Pediatrics·DateMay 7, 2020
Patients with type 2 diabetes who underwent supervised exercise training showed significantly improved heart function and increased cardiovascular fitness compared to those on a low-energy diet. A low-energy diet, however, led to favourable effects on the structure of the heart and reversal of diabetes in 83% of participants.
SourceNational Institute for Health Research·JournalDiabetes Care·DateMar 30, 2020
Researchers from Harvard Medical School and Columbia University discovered that a protein called Rad dampens the activity of voltage-gated calcium channels, which are responsible for heart contraction. When adrenaline stimulates these channels, Rad releases, increasing channel activity and heart beating.
SourceHarvard Medical School·JournalNature·DateJan 23, 2020
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DJI Air 3 (RC-N2) captures 4K mapping passes and environmental surveys with dual cameras, long flight time, and omnidirectional obstacle sensing.
A new University of Guelph study finds that BPS can hinder heart function, especially in females, with effects occurring within minutes of exposure. The study's findings raise concerns about the safety of BPS as a replacement for BPA and suggest banning it from consumer products.
SourceUniversity of Guelph·JournalScientific Reports·DateJan 9, 2020
A study by Queen Mary University of London suggests regular cannabis use may be associated with an enlarged left ventricle and early signs of impaired heart function. However, further research is needed to confirm these findings and understand the cardiac impact of recreational cannabis use.
SourceQueen Mary University of London·DateDec 18, 2019
A study presented at EuroEcho 2019 found that bariatric surgery significantly improved subclinical heart function, reversing abnormal heart structure and function in obese individuals. The surgery also led to improvements in type 2 diabetes, hypertension, and dyslipidaemia, resulting in a lower risk of cardiovascular disease.
SourceEuropean Society of Cardiology·DateDec 5, 2019
A new study from Penn Medicine found that early diagnosis of peripartum cardiomyopathy (PPCM) is associated with improved outcomes in women diagnosed during late pregnancy or shortly after delivery. Black women are disproportionately diagnosed later, which may explain disparities in outcomes.
SourceUniversity of Pennsylvania School of Medicine·JournalHYPERTENSION·DateNov 16, 2019
Creality K1 Max 3D Printer
Creality K1 Max 3D Printer rapidly prototypes brackets, adapters, and fixtures for instruments and classroom demonstrations at large build volume.
Researchers at UC San Diego School of Medicine discovered that genetic variations in NKX2-5 protein affect heart function, revealing a common mechanism across multiple heart-related traits. The study uses skin-derived induced pluripotent stem cells to analyze the role of NKX2-5 variants.
SourceUniversity of California - San Diego·JournalNature Genetics·DateSep 30, 2019
Researchers at Vanderbilt University have developed an antibody to target cadherin-11, a major contributor to inflammation in cardiac fibrosis. The study shows that the antibody can fine-tune inflammation and reduce scarring, leading to improved cardiac function.
SourceVanderbilt University·JournalJCI Insight·DateSep 19, 2019
A study found that human hearts have evolved to handle sustained endurance activity, while sedentary lifestyles lead to more 'ape-like' hearts and increased hypertension. Researchers compared heart function in apes and four groups of humans with varying activity levels.
SourceMassachusetts General Hospital·JournalProceedings of the National Academy of Sciences·DateSep 16, 2019
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GQ GMC-500Plus Geiger Counter logs beta, gamma, and X-ray levels for environmental monitoring, training labs, and safety demonstrations.
Treatment with sacubitril/valsartan significantly improves cardiac structure and function in patients with reduced ejection fraction heart failure. The drug's neprilysin inhibition also reduces blood levels of biomarker NT-proBNP, associated with lower risk of death and hospitalization.
SourceMassachusetts General Hospital·JournalJAMA·DateSep 2, 2019
Anabolic-androgenic steroid use is associated with decreased heart function, as revealed by a study of male weightlifters. The study found that AAS users have thicker hearts and reduced ability to contract ventricular chambers, increasing mortality risk.
SourceEuropean Society of Cardiology·DateSep 1, 2019
A new study suggests that increased levels of the protein sarcospan improve cardiac function by reinforcing cardiac cell membranes, which become feeble in patients with DMD. Sarcospan could also act as a scaffold that supports other essential proteins at the cell membrane.
SourceFlorida State University·JournalJCI Insight·DateJun 14, 2019
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Garmin GPSMAP 67i with inReach provides rugged GNSS navigation, satellite messaging, and SOS for backcountry geology and climate field teams.
Research found that three months of high-intensity interval training improved heart function in adults with type 2 diabetes without medication changes. High-intensity exercise reversed some changes in heart function that precede diabetic heart disease.
SourceUniversity of Otago·JournalMedicine & Science in Sports & Exercise·DateMay 23, 2019
A novel minimally invasive method using catheter-based ultrasound measures cardiac output with similar precision as a traditional device. This technology is less invasive and can be used while patients are awake, making it more clinically practical for young children.
SourceAmerican Society of Anesthesiologists·JournalAnesthesiology·DateMar 18, 2019
A new noninvasive technique has been developed to simulate repairs to the heart's mitral valve with high levels of accuracy. This will enable surgeons to provide patient-specific treatments, potentially reducing recurrence rates after surgery.
SourceUniversity of Texas at Austin·JournalAnnals of Biomedical Engineering·DateJan 30, 2019
A study funded by the American Heart Association aims to investigate whether pyruvate can enhance cardiac output in pediatric patients with low cardiac output syndrome following heart surgery. The researchers hope that this could lead to better recovery times, reduced hospital stays and improved quality of life for these children.
SourceChildren's National Hospital·DateDec 19, 2018
A systematic review of literature found that cardiac rehabilitation attendance is associated with improved sexual function and sexual frequency in patients with cardiovascular disease. The study highlights the need for further investigation into the effectiveness of sexual counseling interventions to improve sexual health outcomes.
SourceElsevier·JournalCanadian Journal of Cardiology·DateDec 6, 2018
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A study published in the Journal of the American Heart Association reveals that reproducing Scn5a missplicing in mice with myotonic dystrophy type 1 (DM1) recapitulates cardiac function defects present in patients. The findings highlight a non-mutational mechanism contributing to arrhythmias and open possibilities for novel interventions.
SourceBaylor College of Medicine·JournalJournal of the American Heart Association·DateSep 28, 2018
Researchers found that maintaining high levels of the protein vinculin in fruit flies' hearts reduced the effects of aging and improved their life span, quality of life, and metabolism. Flies bred with higher vinculin levels lived up to nine weeks, compared to six weeks for typical fruit flies.
SourceAmerican Institute of Physics·JournalAPL Bioengineering·DateJul 17, 2018
A $1.54 million NIH grant will support research on modifying troponin T to improve cardiac function in heart failure. The study aims to develop a new approach for treating this condition by targeting the physiological modification of cardiac troponin T.
SourceWayne State University - Office of the Vice President for Research·DateJul 17, 2018
A wireless device called Vivio accurately detected heart dysfunction in childhood cancer survivors treated with anthracycline chemotherapy. The device displayed high sensitivity and a low false-negative rate compared to cardiac magnetic resonance (CMR) imaging.
SourceAmerican Association for Cancer Research·JournalClinical Cancer Research·DateJun 21, 2018
Aranet4 Home CO2 Monitor
Aranet4 Home CO2 Monitor tracks ventilation quality in labs, classrooms, and conference rooms with long battery life and clear e-ink readouts.
A new preclinical study finds that early BPA exposure may slow heart rates, cause irregular rhythms and calcium instabilities in developing hearts. The research highlights the need for alternative biomaterials to improve patient safety outcomes.
SourceChildren's National Hospital·JournalScientific Reports·DateMay 14, 2018
Researchers found that a defective protein in Huntington's disease disrupts the mTORC1 pathway, leading to cardiac problems. Adjusting this pathway improved heart function in experimental animals, offering new insights into the biology of the disease.
SourceChildren's Hospital of Philadelphia·JournalCell Reports·DateApr 24, 2018
New mouse studies show that tamoxifen and raloxifene improve cardiac, respiratory, and skeletal muscle functions while increasing bone density in muscular dystrophy models. The treatments delay or halt disease progression, reducing muscle pathology and inflammation.
SourceElsevier·JournalAmerican Journal Of Pathology·DateMar 20, 2018
A study of 5,065 participants found that stronger hand grips are associated with a lower heart mass and reduced remodeling of the heart muscle, indicating a reduced risk of cardiovascular events. This suggests that hand grip strength may be an important indicator of cardiovascular health.
SourcePLOS·JournalPLOS ONE·DateMar 14, 2018
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Apple AirPods Pro (2nd Generation, USB-C) provide clear calls and strong noise reduction for interviews, conferences, and noisy field environments.
A study published in PLOS ONE found that menopausal hormone therapy is not associated with adverse changes in cardiac structure and function, but may be linked to some healthier heart characteristics. The research examined 1,604 post-menopausal women and found significantly smaller left ventricular and left atrial chamber volumes.
SourceQueen Mary University of London·JournalPLOS ONE·DateMar 8, 2018
Researchers developed a method to obtain critical information about cardiac function using machines that help failing hearts circulate blood. The new approach may pave the way to self-contained mechanical circulatory support systems for patients suffering from cardiogenic shock after a heart attack.
SourceAmerican Association for the Advancement of Science (AAAS)·JournalScience Translational Medicine·DateFeb 28, 2018
The NRG Oncology trial found that trastuzumab did not negatively affect cardiac function in patients with node-positive, HER2-positive breast cancer who survived without cancer recurrence. Both groups maintained good cardiac function at a median of 8.8 years after treatment.
SourceNRG Oncology·JournalJournal of Clinical Oncology·DateJan 3, 2018
Research published in Experimental Physiology found that spinal cord injury affects the heart, with changes dependent on injury severity. The study suggests preserving more nerve fibers can improve heart function in individuals with spinal cord injury, who are at higher risk of heart disease.
SourceThe Physiological Society·JournalExperimental Physiology·DateDec 12, 2017
Researchers at Cincinnati Children's Hospital Medical Center found that blocking a molecular pathway can stop or slow cardiac fibrosis, organ enlargement, and preserve heart function. The study provides new insights into what causes cardiac fibrosis and opens the potential for finding new therapeutic approaches.
SourceCincinnati Children's Hospital Medical Center·JournalNature Communications·DateSep 28, 2017
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CalDigit TS4 Thunderbolt 4 Dock simplifies serious desks with 18 ports for high-speed storage, monitors, and instruments across Mac and PC setups.
Researchers found that a fatty acid-derived bioactive molecule called lipoxin improved heart function after a heart attack by inducing the resolving immune response. Lipoxin treatment also reduced left ventricle and lung mass-to-body-weight ratios, improving ejection fraction, and decreased kidney inflammation.
SourceUniversity of Alabama at Birmingham·JournalScientific Reports·DateSep 6, 2017