Articles tagged with Jet Lag
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A new study from Texas A&M University reveals that circadian disruptions change the structure of mammary glands, weaken immune defenses, and fuel aggressive breast cancer. Disabling an immune checkpoint molecule called LILRB4 helps restore the immune system's ability to fight back.
A team of researchers at Washington University in St. Louis developed a computational tool to reveal connections in the mouse suprachiasmatic nucleus (SCN), the body's central circadian pacemaker. The study identified five functional cell types and found that a small subset of 'hub' cells are critical to SCN timekeeping.
Research reveals that chemotherapy impairs molecular and behavioral measures of the primary biological clock found in the brain. In a study on female mice, paclitaxel treatment disrupted circadian rhythm-related gene expression and behavioral adaptations to light challenges.
Researchers found that sleep duration returns to baseline within two days, but changes in sleep timing and structure can take more than a week, with eastward travel causing the most disruption. The study analyzed 1.5 million nights of data from wearables like Oura Ring.
Daily electronic screen use is associated with approximately 50 minutes less sleep per week and later bedtimes in adults. The findings suggest that these disruptions are not limited to children and adolescents, particularly among those with evening chronotypes.
A study of 25,000 NBA matches found that home teams from the Western Time Zone Area have a near 10% better win ratio when playing against Eastern Teams. The researchers suggest that elite basketball coaches and teams should consider the physical and mental effects of time zone travel on game planning.
A study by Johns Hopkins Medicine has identified teneurin-3 as a key protein for stabilizing the body's circadian rhythms. The protein helps wire the brain during neural development to allow for stable responses to light changes, reducing the impact of disruptions on sleep and other cycles.
Repeated, chronic jet lag negatively impacts student-athlete health and performance in academics and sports. Strategies to reduce consequences include preadaptation before travel and sufficient time for circadian adjustment after arrival.
A team of researchers from Kyoto University found that the pituitary vasopressin system is crucial for building a robust circadian clock in the suprachiasmatic nucleus. This discovery has led to the development of potential treatments for jet lag, which currently target only the suprachiasmatic nucleus.
A University of Bristol-led study found that circadian misalignment associated with 'jet-lag' disrupts hormones regulating appetite, leading to increased food consumption. The study suggests promising targets for drug treatments adapted to treat eating disorders and obesity.
A new study suggests that synchronizing internal clocks can help alleviate jet lag and age-related problems. Researchers found that eating a larger meal in the morning can help overcome jet lag, while constant nighttime eating can lead to misalignment between internal clocks.
Researchers developed a new mathematical model to study circadian rhythm resilience and develop ways to improve it in individuals with weak internal clocks. Sustained disruptions can lead to disorders like diabetes and memory loss.
Researchers at King's College London found irregular sleep patterns are associated with lower overall diet quality, higher intakes of sugar-sweetened beverages, and lower intakes of fruits and nuts. This is linked to differences in gut microbiome composition, with certain species having 'unfavourable' associations with health.
Researchers have identified the structure of the circadian rhythm photosensor and its target in fruit flies, revealing key components of the circadian clocks. The study also shed light on how DNA damage is repaired in a cell and found genetic variations that help flies adapt to changing latitudes.
Research at the University of Massachusetts Amherst shows that circadian disruption from jet lag can harm adult neurogenesis, which supports learning and memory. The study found that the Cryptochrome 1 gene regulates this process and that misalignment can lead to adverse health effects such as dementia and mental illness.
Researchers at UC San Diego and UC Merced developed a high-throughput method to study the circadian clock in real time, shedding light on its internal functions. The study found that kinases play a crucial role in relaying the circadian rhythm from the core oscillator to gene expression.
Researchers found that people living with HIV have a significantly delayed internal body clock, consistent with the symptoms of jet lag. This disruption may contribute to increased health problems experienced by those with HIV. The study suggests a strong need for further research on younger people living with HIV in other countries.
Researchers discovered a molecular link between disrupted circadian rhythms and lung tumor growth, implicating a cancer-signature gene known as HSF1. Disrupted clocks may trigger lung tumors in individuals with irregular sleep patterns or night shifts.
A research team has identified a specific cell group in the brain that regulates shifts in the sleep-wake rhythm caused by psychostimulants. The hypothalamic dopamine locus is responsible for modulating circadian rhythms and gates the effect of psychostimulants, leading to increased alertness and activity.
A landmark study published in Frontiers in Physiology suggests that eastward travel can significantly impact home teams' performance in the NBA Finals. The research found that teams playing with 1 hour of eastward jet lag experienced a 0.72-point drop in point differential compared to teams without jet lag.
A new study suggests that prebiotics can help realign sleep-wake cycles and core body temperature after chronic disruption of rhythms, hosting health-promoting microbes and a different metabolome. Researchers hope to develop customized prebiotic mixtures for individuals with frequent circadian disruptions.
Research published in Occupational & Environmental Medicine found that night owls are more likely to experience poor health, insomnia, and social jet lag, leading to underperformance at work. The study also linked evening chronotype to a higher risk of early retirement due to disability.
Researchers at UC San Francisco, UNC and UB have discovered novel melatonin receptor molecules that can modulate circadian rhythms. These molecules attach to the MT1 melatonin receptor with high selectivity, generating cellular responses opposite to those of melatonin.
A University of Barcelona study found that irregular eating schedules during weekends, known as eating jet lag, may contribute to increased body mass index (BMI) and obesity. Researchers suggest that maintaining regular eating and sleeping schedules can help prevent weight gain.
An expert review concludes that melatonin for jet lag may not be effective in relieving symptoms due to scant evidence. The review suggests that non-drug treatments like timing exposure to bright light and altering bed and mealtimes may be more complicated.
A study of 804 adolescents found that adolescent girls with an evening chronotype who prefers going to bed and waking up later tend to have bigger waistlines and greater fat mass. This association holds true even after adjusting for other lifestyle factors. The study suggests that addressing irregular sleep patterns may be important in...
A new study funded by the National Institutes of Health found that teenage girls who go to bed later are more likely to gain weight compared to those who sleep earlier. The research also showed a significant association between late bedtime and increased waist size and body fat in young females.
Researchers found that inducing jet lag in fruit fly models of Huntington disease protected the flies' neurons. The team identified a circadian clock-controlled gene that also protected the brain when knocked down. This study suggests that targeting this gene could potentially slow the progression of neurodegenerative diseases.
A new study published in The Journal of Physiology found that exercising at 7 am or between 1 and 4 pm advances the body clock to an earlier time, while exercising between 7 and 10 pm delays it. This research has implications for counteracting jet lag and shift work.
Researchers found that sustained periods of low Twitter activity were correlated with sleep patterns, while the nightly lull shifted to later times on weekends. The magnitude of 'Twitter social jet lag' varied seasonally and geographically, with the West Coast experiencing less lag.
A study analyzing Twitter data from over 246,000 users found that social media usage largely reflects daily work schedules and school calendars. The data show a daily slowdown in tweets at night, with weekend usage shifting later than weekdays.
Scientists at Washington University discovered that activating only 10% of VIP neurons can rapidly shift a mouse's daily schedule. The study suggests that VIP neurons produce vasoactive intestinal polypeptide, an essential compound for synchronizing daily rhythms.
A team of researchers has discovered compounds that can regulate the circadian rhythm in human cells, including a well-known anti-aging supplement. The supplement was found to reduce jet lag symptoms in mice, providing hope for the treatment of circadian clock disorders arising from jet lag and shift work.
A new study found that students whose circadian rhythms were out of sync with their class schedules received lower grades due to social jet lag. The research analyzed online activity data from nearly 15,000 college students and suggested individualizing education to match students' natural rhythms for better academic success.
A new study finds social jet lag, delaying sleep on weekends, associated with increased risk of heart disease and worsening mental health. The research suggests that maintaining a regular sleep schedule may be an effective preventative treatment for these health problems.
Researchers at the University of Surrey discovered that delaying meal times by five hours can delay blood sugar rhythms, suggesting a potential solution for alleviating symptoms of shift work and jet lag. This finding indicates that separate circadian clocks govern glucose metabolism and fat levels in the blood.
New cells in retina found to directly affect biological clock by sending signals to brain region regulating daily rhythms. Disruption of circadian rhythms linked to health issues like gastrointestinal and cardiovascular disorders, depression, and cancer.
Researchers found that eastward travel had significant negative effects on MLB players' performance, particularly in base running and home runs allowed. The study's findings suggest that jet lag can have a substantial impact on team performance, even erasing the traditional home field advantage.
A recent study from Texas A&M University reveals that consuming saturated fats at certain times can disrupt the body's internal clock and trigger metabolic disorders. The research suggests that timing of fat consumption plays a crucial role in inflammation and disease prevention.
Researchers have discovered how light disrupts biological clocks and propose a two-day recovery time for jet lag. They found that weakening synchronization among neurons governed by circadian patterns enables rapid adaptation to new time zones.
A new iPhone app called Entrain offers custom schedules of light and darkness to help travelers adjust to new time zones. By following these schedules, users can reduce their jet lag recovery time by up to three days.
A study at Washington University in St. Louis found that a small molecule called VIP can temporarily desynchronize brain cells, but also enables them to re-synchronize more quickly to abrupt shifts in daily light-dark schedules. This effect may be useful for travelers and shift workers who struggle with jet lag.
Scientists at the University of Notre Dame have identified a protein called SIK1 that can help regulate the body's internal clock. By blocking its activity, researchers found that mice adjusted faster to changes in their environment, suggesting that SIK1 could be a target for treating jet lag and shift work disorders.
Differences in jet lag severity may be rooted in how the circadian clock sets itself, with advanced and delayed mechanisms differing at a molecular level. This finding could provide clues for understanding jet lag and offer potential remedies.
Research by University of California, Berkeley psychologists found that chronic jet lag causes persistent changes in the brain's hippocampus, leading to memory and learning problems. The study, which used female Syrian hamsters as subjects, showed that even after recovery from jet lag, the brain continued to experience deficits.
Researchers found that individual organs' internal clocks synchronize with the external time at varying speeds, leading to discoordination of physiological processes. The adrenal gland plays a key role in this adaptation, and manipulating corticosterone production can help rodents recover from jet lag faster.
A new study has identified a key role for adrenal glucocorticoids in resetting the internal body clock, a finding that could lead to new treatments for jet lag. The research also highlights the importance of timing and location in regulating circadian rhythms.
A new software program uses mathematical modeling to prescribe optimal light exposure for avoiding jet lag, resulting in quicker re-synchronization and improved performance. The method considers background light levels and time zones traveled, providing personalized recommendations for bright light intervention.
Scientists have identified the two neural centers responsible for regulating sleep patterns, revealing that disruptions to these centers can cause jet lag. The study found that deep sleep is more closely tied to light-dark cycles, while REM sleep follows a separate internal clock, leading to a delay in adaptation to new schedules.
A study by University of Notre Dame biologist Giles Duffield and his team sheds new light on the circadian clock's response to light signals, focusing on the Inhibitor of DNA-binding 2 (Id2) gene. The research has important implications for understanding the development and functioning of the circadian clock in the brain and peripheral...
Researchers at Monash University found a new drug, tasimelteon, that can effectively shift melatonin levels to alleviate jet lag and sleep disorders. The drug has the potential to improve sleep quality for patients with transient insomnia caused by time zone changes.
Air crew who work repeated long haul routes are at risk of menstrual cycle problems, transient psychotic disorders, and major affective disorders due to the effects of jet lag. The symptoms can last for several days and include disrupted sleep patterns, mood changes, and gastrointestinal difficulties.
A new study found that combining bright light and melatonin can help advance the circadian clock and reduce jet lag. The combination produces a larger phase advance than bright light alone, making it a practical solution for travelers.
Researchers investigated the effects of caffeine (SRC) and melatonin (Mlt) on jet lag symptoms. The study found that Mlt decreased subjective sleepiness but not objective sleep quality, while SRC reduced sleepiness for a few days with negative effects on recovery sleep. Additional studies are needed to evaluate their full effects.
Scientists found that the biological clock in mice and rats responds to temperature changes rather than light signals. This discovery has significant implications for understanding jet lag and could lead to new treatments for related conditions.