Research reveals that Sulf1 is essential for both reward-dependent and aversion learning, highlighting its critical role in adult brain function. The enzyme acts through distinct dopamine D1 and D2 receptor pathways, underscoring its importance in neural circuits involved in learning.
A cohort study found associations between exposure to multiple fine particulate matter components and increased depression risk among US Medicare population members. The study highlights the importance of targeted regulation to protect vulnerable populations from harmful air pollution.
Researchers found that a pyrite-oxidizing microbe preserves up to 90% of atmospheric oxygen in sulfate, offering insights into microbial activity in ancient environments. This discovery could help analyze oxygen isotope data from Martian sediments for signs of life and provide clues to environmental conditions on early Earth.
Scientists found that anaerobic microbes in wetlands can remove up to 70% of methane in oxygen-deprived soils, but their ability to do so is threatened by rising temperatures. When scientists simulated a hotter future, methane emissions spiked under hotter temperatures alone.
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Researchers discovered that sulfur bacteria from the Desulfobacteraceae family work together like a team to break down diverse organic compounds. By analyzing six strains, they found similar molecular strategies and a highly energy-efficient central metabolism pathway, enabling them to thrive in oxygen-free environments.
A recent study by Cornell University researchers suggests that the 2020 regulatory changes in international shipping emissions led to a significant increase in global temperatures. The study found that removing sulfur dioxide from shipping fuel increased the planet's temperature by 0.08 degrees Celsius.
A study by Chiba University researchers has identified 106 compounds in pregnant women's serum samples, including phthalates, nitrogenous compounds, and parabens, which may impact biological pathways. The study proposes a non-targeted approach for detecting foreign chemicals and evaluating their potential health effects.
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A new study finds that volcanic eruptions triggered a sudden and devastating cooling event, causing mass extinctions in the Triassic period. The research contradicts previous theories that suggested increased carbon dioxide led to warming temperatures.
Researchers found that rising temperatures accelerate weathering of rocks in the Canadian Arctic, leading to increased CO2 release and a positive feedback loop. This process could contribute significantly to climate change, with predicted emissions doubling by 2100 under moderate emission scenarios.
A new study finds that reduced sulfur emissions from shipping industry likely contributed to nearly 20% of record-breaking 2023 warmth, while regulations also accelerated warming. Further research is needed to understand the magnitude of climate response.
A new study reveals that the Sierra Nevadas are a significant source of groundwater for California's Central Valley aquifer, with some areas relying almost entirely on it. The research found that the groundwater is mixed in age, with some water being as young as 4 years old and others dating back over 40,000 years.
A novel genus, Candidatus Alkanivoras nitrosoreducens, is described as potentially performing nitrite-driven anaerobic ethane oxidation. The study reveals a prospective fumarate addition pathway for anaerobic ethane oxidation and a complete denitrification pathway for nitrite reduction.
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A University of Arizona-led study explores sulfur's significance in the emergence of life on Earth, shedding light on its possible role as an RNA precursor. The research suggests that sulfur's reactivity could have hindered its availability for origin-of-life chemistry.
Scientists have developed a cage-like molecule to trap sulfate in water, which could help control its concentration in health, industry, and environmental management. The molecular trap can be prepared inexpensively from off-the-shelf chemicals and has potential applications in medicine, such as treating cystic fibrosis.
A new study by the University of Technology Sydney suggests that office air conditioning can reduce the risk of harm from wildfire smoke. The researchers found that air conditioning filters in UTS Buildings 4 and 7 captured a significant portion of wildfire smoke, reducing exposure to toxic particles for staff and students.
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Apple MacBook Pro 14-inch (M4 Pro) powers local ML workloads, large datasets, and multi-display analysis for field and lab teams.
A new study by the University of Washington challenges previous findings of declining phytoplankton in the North Atlantic. The researchers analyzed an ice core from central Greenland and found that human-generated pollutants changed the atmosphere's chemistry, offsetting a decrease in marine productivity.
The study reveals that the midgut gland of Japanese scallops is a valuable source of fucosylated heparan sulfate, exhibiting anticoagulating and neurite outgrowth-promoting activities. Fuc-HS shows resistance to GAG-degrading enzymes, indicating its unique structure with a fucosyl group attached to GlcA.
A new potential drug target has been identified for Alzheimer's disease by Rensselaer researchers, focusing on the interaction between ApoE and heparan sulfate. The study suggests that modulating this interaction could slow the progression of the disease.
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A study led by University of Houston researchers found that the Texas Gulf Coast is polluted with high concentrations of sulfate, a major component of particulate matter. The pollution originates from anthropogenic shipping emissions and chemical processing, making it particularly hazardous to human health.
Chung-Ang University researchers develop a novel flexible supercapacitor platform with vertically integrated gold electrodes in a single sheet of paper. The design shows low electrical resistance, high foldability, and good mechanical strength, making it suitable for wearable devices.
Studies elucidate key aspects of traditional Chinese compounds and modern cancer therapeutics, highlighting the efficacy of R. serra in treating colitis and identifying active components of Gan Cao in treating pneumonia. A new radiolabeled antibody-based probe for detecting PD-L1 expression in cancers also provides a novel approach to ...
A study by Pusan National University researchers investigates the effects of mild acid hydrolysis on sulfated fucans in sea cucumbers and sea urchins. The results show selective 2-desulfation, leading to an 8-sugar-long oligosaccharide production.
A new study published in Geophysical Research Letters reveals that even dormant volcanoes release a surprisingly high amount of sulfur into the Arctic atmosphere. This finding has significant implications for understanding Earth's atmosphere and its relationship with climate and air quality.
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A UK program using magnesium sulfate to prevent cerebral palsy in premature babies has been shown to be both effective and cost-effective. The PReCePT program increased the use of magnesium sulfate by 9.5 percentage points on average, resulting in a lifetime saving of £3 million.
Researchers from the Max Born Institute found that magnesium ions reduce ultrafast fluctuations in water's hydration shell, slowing solvation dynamics. The study reveals a short-range effect of individual ion pairs on dilute aqueous systems.
A new study by Tokyo University of Science researchers reveals that dendritic cell immunoreceptor (DCIR) plays a crucial role in the development of colorectal tumors. Blocking DCIR may prevent ulcerative colitis and colon cancer, offering a potential therapeutic target for treating these diseases.
Researchers from Tokyo University of Science discovered that bony fish head cartilage contains abundant proteoglycans, including aggrecan, with similar CS structures to salmon nasal cartilage. This finding reveals the potential of sturgeon as an alternative source of CSPGs for health food formulations.
A team of researchers has confirmed that a volcanic eruption in 1628 B.C. was not Thera but Alaskan volcano Aniakchak II, helping to narrow down the potential dates for the Thera eruption's occurrence between 1611 B.C., 1562-1555 B.C. and 1538 B.C.
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A new study reveals that salt marsh grass in Georgia's coast relies on beneficial bacteria in its roots to access nutrients, improving plant productivity. The research provides insights into the importance of soil microorganisms in maintaining ecosystem health and supporting restoration efforts.
Scientists have discovered that the onset of microbial fertilizer factories on the Earth's seafloor roughly 2.6 billion years ago was a crucial step in the rise of oxygen levels during the Great Oxidation Event. This recycling process fueled photosynthetic bacteria, which increased oxygen production and paved the way for complex life t...
A fresh analysis suggests that the global cooling effect of the Hunga Tonga-Hunga Ha'apai volcano eruption will be smaller than expected. However, the researchers warn that a one-time-only event may not be sufficient to overwhelm the longer-term global warming tendency.
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A recent study by ITQB NOVA scientists uncovered the crucial role of a small marker protein, DsrD, in increasing metabolic activity for sulfate respiration. The findings suggest that DsrD acts as an allosteric activator of the DsrAB dissimilatory sulfite reductase, enhancing energy efficiency in microbial metabolism.
A recent study by NTU Singapore has found a strong link between increasing air pollution and the rise of lung adenocarcinoma, a type of cancer. The study also discovered that declining smoking rates are associated with lower incidence of lung squamous cell carcinoma.
Researchers developed a simple and fast method to analyze sulfur isotopes, enabling the detection of seawater intrusion into freshwater systems. This method can help investigate chemical changes in environments affected by sea level rise.
Researchers at Boston University School of Medicine discovered that charged biopolymers like heparan sulfate and heparin accelerate amyloid aggregation in various organs. This understanding will guide targeted drug design for deadly diseases such as Alzheimer's, Parkinson's, and type-2 diabetes.
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Researchers analyzed ice core data from Greenland to understand the relationship between sulfur dioxide emissions and sulfate aerosols. They found that sulfate levels have declined more slowly than sulfur dioxide emissions, especially in wintertime, due to a reaction that partially mitigates reductions.
Researchers from Max Planck Institute for Marine Microbiology and Weizmann Institute of Science explain how methane carbon isotopes behave differently than expected in the deep sea. They found that sulfate availability governs the isotope effects in anaerobic methane oxidation, leading to 13C-depleted methane.
Researchers have discovered a new method for converting toxic copper ions into stable single-atom copper using bacteria found in copper mines. This process is safer and more efficient than current methods, which often require harsh chemicals and labor-intensive processes.
Purdue University engineers develop ultra-white paint that reflects up to 98.1% of sunlight, keeping surfaces cooler than surroundings. The paint, made with barium sulfate particles of different sizes, can reduce the need for air conditioning by 10 kilowatts.
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Apple iPad Pro 11-inch (M4) runs demanding GIS, imaging, and annotation workflows on the go for surveys, briefings, and lab notebooks.
Researchers have developed a novel method for rapid and accurate glycan sequencing, reducing the time required from years to minutes. The technique utilizes a nanopore device and machine-learning software to identify sugar chains based on electrical signals generated as they pass through a tiny hole.
Researchers propose that underground salts and melting ice are responsible for Martian landslides, including the seasonal Recurring Slope Lineae features. Lab experiments suggest that thin layers of liquid-like water form near -50 °C, followed by gradual melting, which could lead to surface changes and dust storms.
Researchers discovered that triplatinNC changes the geometry of heparan sulfate, blocking its splitting and preventing tumor cell migration. This finding opens possibilities for designing anti-metastatic platinum complexes.
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Researchers identified a protein, factor D, that enables the virus to turn the immune system against healthy cells. Inhibiting this protein can curtail inflammatory reactions and prevent cell destruction.
Researchers at University of California San Diego discovered SARS-CoV-2 uses heparan sulfate to bind to cells. The team found two approaches to reduce virus infection by 80-90%: removing heparan sulfate with enzymes or using heparin as bait, repurposing a widely used medication.
Researchers developed a model that suggests large volcanic intrusions were responsible for major changes in oceanic sulfate over the past 120 million years. The study found that these events were coupled with changes in sulfur burial efficiency and led to significant increases in seawater sulfate concentrations.
Research found that combining magnesium sulfate and corticosteroids before birth reduces severe neurodevelopmental impairment and death in extremely preterm children. The study analyzed medical records of over 3,000 infants born between 2011 and 2014.
A new method called Shotgun ion mobility mass spectrometry sequencing (SIMMS2) has been invented to map the structures of heparan sulfates, which play key roles in regulating biological functions. This breakthrough could lead to the development of new therapeutics for diseases such as cancer and neurodegenerative disorders.
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Researchers discovered that black carbon catalyzes sulfate production during regional haze events in the North China Plain, leading to significant air quality issues. The study suggests reducing SO2, NOx, NH3, and black carbon emissions is crucial to improve air quality.
Soil researchers found significant movement of sulfate into subsoils and improved water quality after implementing the Clean Air Act Amendment in 1990. However, soils still exhibit chemical imbalances, indicating a long-term recovery process.
Researchers have identified three mechanisms by which nitrogen oxides affect sulfate production, revealing that both low and high NOx levels can promote sulfate formation. The study highlights the need for policymakers to control NOx emissions in a way that balances reductions in both SO2 and NOx.
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Researchers demonstrate the production of a wide range of sulfated aromatic compounds, including antifouling agents and pharmaceuticals, using microbial hosts. The process enables the large-scale production of sulfated phenolic compounds, offering potential applications in medicine, nutraceuticals, and other industries.
The Pulpí geode is an 11-meter hollow ovoid with crystal-paneled walls, formed from gypsum crystals up to 2 meters in size. The team studied the geology and geochemistry of the abandoned mine where the geode was found, revealing that the crystals formed at around 20 °C.
Penn State researchers developed a testing protocol using existing water chemistry tests to detect new methane gas leaks from oil and gas drilling. The study found 17 out of 20,751 samples showing possible signs of methane contamination, highlighting the potential for widespread methane migration.
Researchers spot sodium chloride on the icy moon Europa, potentially indicating a hydrothermally active ocean floor and making it a geologically interesting planetary body. The discovery was made using visible light spectral analysis, which revealed distinct absorption patterns in the visible spectrum.
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Researchers have discovered a new mechanism for the formation of strontium-rich barite in seawater, which could lead to more efficient methods for removing toxins from water. The study found that organic matter can create conditions that promote the nucleation and incorporation of strontium into barite precipitates.
Research reveals that sugar released into bloodstream enters brain during septic shock, causing premature mental aging and memory loss. The study provides a clear target for drug therapy: binding to the sugar or converting it to non-impairing compounds.
Researchers at Purdue University discovered a molecule called heparan sulfate that can prevent viruses from escaping cells, raising questions about the safety of gene therapy delivery. The study highlights the need to consider how engineered viruses will exit cells to avoid unintended consequences.
Researchers have revised the history of big, climate-altering volcanic eruptions using a new method that accurately identifies airborne particles in Antarctic ice cores. The study confirms many events and corrects misidentifications, revealing new information on large stratospheric eruptions over the past 2,600 years.
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A team of scientists has uncovered a new compound produced by the bacterium Chlorobaculum tepidum, which is found in volcanic hot springs. The discovery reveals that the microbe modifies a previously unknown thiol to produce a compound called N-methyl-bacillithiol, which plays a crucial role in the sulfur cycle. This finding has signif...
Researchers from China and the US analyzed five sulfur isotopes in aerosol, SO2, and coal samples to determine their sources. The study reveals that photochemical reactions in the stratosphere produce sulfate aerosols enriched with 33S, while biomass and fossil fuel combustion yield sulfates depleted in 36S.