Articles tagged with Hallucinations
A new Northwestern University study has discovered a novel biomarker of schizophrenia that could also serve as a new drug candidate to treat the cognitive symptoms of the disorder. The study found that levels of the protein Cacna2d1 signal are reduced in patients with schizophrenia, resulting in overactive brain circuits.
A recent study has found that auditory verbal hallucinations in schizophrenia may stem from a disruption in the brain's ability to recognize its own inner voice. Researchers used EEG to measure brainwaves as participants listened to audio and imagined speaking, revealing a stronger reaction in people with schizophrenia who heard voices.
The project will develop prediction algorithms using AI and a novel cognitive assessment tool to identify individuals at high risk for crisis. The digital platform, available at no cost, will provide personalized models to predict clinical health outcomes, including symptom escalation, recovery time, and rehospitalization.
A single dose of MM120 (lysergide) produced a dose-dependent reduction in anxiety in participants with moderate to severe generalized anxiety disorder. The study supports the efficacy of MM120 and informs dose selection for phase 3 pivotal trials.
The study found direct evidence of psychoactive plant use in ancient Chavín de Huántar, Peru, revealing exclusive rituals that reinforced the social hierarchy. The use of hallucinogens created an air of mystique and control, convincing leaders of their mystical power.
Research by Professor Stephen M. Stahl suggests that Jackson Pollock incorporated images into his pre-drip paintings, possibly due to spatial skills linked to bipolar disorder. The same images appear in multiple drip paintings, implying a deliberate encoding of images.
A new AI tool generates realistic satellite images of future flooding, which can help communities visualize and prepare for approaching storms. The method combines a generative artificial intelligence model with a physics-based flood model, producing more accurate and realistic images than an AI-only approach.
Researchers found that people with schizophrenia who experience auditory hallucinations have impaired brain processes, including a 'broken' corollary discharge and 'noisy' efference copy. This impairment may contribute to the loss of ability to distinguish reality from fantasy.
A new study found that flickering light can cause standing waves of brain activity, leading to hallucinatory patterns. Researchers used high-speed cameras to track mouse brain activity while exposed to flashing lights, revealing waves of neural activity that resembled ripples in a pond.
A new study shows that psilocybin initiates a pattern of hyperconnectivity in the brain linked to the ego-modifying effects and feelings of oceanic boundlessness. The findings provide insights into how the brain works on psychedelic drugs and their potential use to treat psychiatric disorders.
Researchers found that people with Parkinson's disease who experience presence hallucinations overestimate the number of people in a room due to a perceptual disorder. The study used virtual reality and robotics to induce presence hallucinations and measure susceptibility, developing an online test for early detection.
Calls to US poison centers involving psilocybin among teens and young adults tripled and doubled, respectively, after decriminalization, leading to alarming concern over potential long-term consequences. Most calls involved intentional consumption, with adverse reactions including hallucinations, agitation, and heart rate issues.
A new blood test developed by Indiana University School of Medicine has identified biomarkers that can objectively measure schizophrenia severity and predict future risk. The test enables personalized treatment matching, reducing uncertainty and improving patient outcomes.
A study comparing dreams from Western and non-Western populations found that non-Western groups produced more cathartic and socially-oriented dreams, while Western groups had more threatening but less emotionally resolving dreams. The results suggest a strong link between societal norms and the function of dreams.
A new study published in PNAS reports surge of gamma activation in dying brains of humans and animals post-cardiac arrest, hinting at conscious-like activity.
A study found that a 21-question pre-visit survey on a tablet significantly increased the detection of psychosis symptoms in young people. However, it did not reduce the time between first psychotic symptoms and treatment. The technology-based screening improved clinical decision-making but highlighted challenges in scaling up programs.
A study of 137 children with early-onset psychosis found that over 70% had copy number variants, a common cause of neurodevelopmental disorders. The research suggests that chromosomal microarray testing can bring closure to families and improve treatment outcomes.
Recent advances in neuroimaging technology show promise in helping tES to effectively treat visual hallucinations (VH) in psychiatric disorders. These advances, combined with individualized modeling techniques and advanced electrical field modeling, may provide a sound foundation for subsequent research on using VH.
Researchers at City University of Hong Kong discovered a new neural mechanism that enables animals to perceive and integrate environmental cues, such as air puffs and sounds, to initiate defensive behavior. This finding has implications for understanding schizophrenia patients' auditory hallucinations.
Researchers at the University of Leicester created novel body-maps of hallucinations, documenting feelings and sensations in the body during psychosis. These maps revealed recurrent concentrations of feelings like pain, heat, or tension in specific body areas.
A new study found that schizophrenia is associated with a loss of excitation but an increase in inhibition, resulting in hallucinations. The researchers used EEG data from 107 participants to demonstrate decreased synaptic gain, which may guide pharmacological and neurostimulation treatments.
Researchers develop a robotic-medical device and procedure to safely induce presence hallucinations in Parkinson's patients, providing a new diagnostic tool for the disease. The study findings suggest that the test may help predict the severity of the disease's progression.
A new study in mice and people offers a promising entry point to developing new therapies for schizophrenia. Researchers found that hallucination-like events were more common among individuals who experienced spontaneous hallucinations, suggesting a link between brain circuits underlying both human and mouse minds.
A study by Weizmann Institute of Science researchers found that spontaneous brain activity in the visual centers can trigger vivid visual hallucinations in blind individuals with Charles Bonnet syndrome. The findings suggest a shared neural system for vision, imagination, and hallucination.
Researchers at Columbia University Irving Medical Center found a potential neurobiological mechanism for hallucinations and delusions that fits within the hierarchical model of psychosis. The study suggests that these symptoms share a common mechanism but also depend on symptom-specific pathways.
A double-blind clinical trial investigates the effectiveness of ondansetron, a cancer anti-sickness drug, in alleviating hallucinations in people with Parkinson's. The study aims to find new treatments for this challenging symptom, which affects 75% of UK Parkinson's patients.
A pilot study suggests meditation-relaxation therapy can reduce the frequency and severity of sleep paralysis. Participants experienced a significant decrease in sleep paralysis episodes and hallucination disturbances after treatment.
A study published in Epilepsia journal found that 8% of individuals with a history of seizures report hallucinations, which are associated with a higher risk of mental health disorders and suicidal behavior. The study highlights the importance of assessing hallucinations in epilepsy clinics to identify high-risk patients.
Researchers found that patients with schizophrenia who experienced auditory hallucinations had abnormal tonotopic organization of the auditory cortex, established in infancy. This suggests that the vulnerability to develop 'voices' is probably established many years before symptoms begin.
An international team of anthropologists discovered a ancient ritual bundle in southwestern Bolivia containing multiple psychoactive substances, including cocaine, DMT, and ayahuasca. The researchers believe the shaman who owned this pouch consumed multiple plants simultaneously to produce different effects or extend their hallucinations.
A study found that a hallucinogenic drug reduces signaling in the visual cortex, leading to altered timing of neuron firing and triggering visual hallucinations. The research has implications for understanding neurological underpinnings in disorders like schizophrenia.
Research from University of Queensland shows that heightened brain activity in the visual cortex is associated with visual hallucinations in people with macular degeneration. The findings could help reduce misdiagnosis and improve diagnosis of Charles Bonnet Syndrome.
A recent study found that sleep paralysis and dream-like hallucinations are prevalent in student athletes, with 18% and 24% of the sample reporting occasional experiences. These symptoms were independently associated with symptoms of depression, even after controlling for sleep duration and quality.
Researchers have established a link between childhood trauma and severe hallucinations in schizophrenia, offering new treatment hope. The study found that childhood trauma was associated with hallucinations and delusions, and may help empower young patients to make informed decisions about their mental health.
Researchers at Columbia University Irving Medical Center found that people with schizophrenia who experience auditory hallucinations tend to hear what they expect, an exaggerated version of a perceptual distortion. Elevated dopamine can exacerbate distorted perceptions.
A study published in Schizophrenia Research found a positive association between corpus callosum integrity and musical aptitude, while reduced integrity was linked to hallucination proneness. Researchers suggest that musical training could potentially counteract an individual's predisposition to hallucinations.
A randomised controlled trial found that avatar therapy was more effective at reducing hallucinations at 12-week follow-up, and had a large effect size. Patients who received avatar therapy experienced rapid improvements in their symptoms, with some reports of complete disappearance after 12 weeks.
Research found disconnections in brain areas involved in attention and visual processing may contribute to visual hallucinations in individuals with Parkinson's disease. The study used fMRI to examine connectivity between brain areas, showing decreased synchronization in patients with visual hallucinations.
A large randomised trial found that digital cognitive behavioural therapy for insomnia improved not only sleep but also reduced symptoms of depression, anxiety, and hallucinations. The findings suggest that addressing sleep problems may play a causal role in the development of some mental health symptoms.
Researchers have identified a specific brain area involved in 'hearing voices' in schizophrenia and found that targeting it with high-frequency magnetic pulses can improve symptoms. In a controlled trial, 34.6% of patients showed significant response to treatment, while only 9.1% of controls did.
A new Yale-led study reveals that people with schizophrenia and other psychotic illnesses exhibit altered brain activity when induced to hallucinate. The study suggests that the ability to learn these hallucinations are not real may help identify those in need of psychiatric treatment.
A new study suggests that auditory hallucinations may arise from top-down brain processing, driven by strong associations between sensory inputs and mental concepts. Participants who experienced hallucinations showed strong beliefs about the association, which drove their tone hallucinations.
Research found structural differences in brain regions of people with schizophrenia who experience hallucinations compared to those without hallucinations. The paracingulate sulcus, a fold towards the front of the brain, was shorter in individuals prone to hallucinations.
Researchers found that individuals with early signs of psychosis relied more heavily on prior knowledge to interpret ambiguous images, leading to improved task performance. This suggests an altered balance in normal brain functions contributing to the emergence of mental illness symptoms.
A comprehensive international study found that approximately five percent of the general population experiences hallucinations and delusions at some point in their lives. The study, involving over 31,000 participants from 19 countries, revealed that these experiences can be temporary and not always linked to serious mental illness.
A recent study found that adolescents with psychological symptoms often exhibit visual distortions and hallucinations before developing a full-blown mental disorder. The researchers also discovered that these symptoms are strongly linked to self-destructive thought processes, which can increase the risk of suicide.
A Rutgers researcher discovered consistent brain patterns in the human brain, regardless of activity level, which could lead to a better understanding of serious mental health conditions. The study's findings suggest that the prefrontal cortex, involved in high-level thinking, may be altered in people with severe mental illness.
A 60-year-old woman with hearing impairment experiences unusual music hallucinations that are familiar to her husband but not herself. The case raises intriguing questions about the nature of memory and forgetting.
Researchers developed an avatar system to control hallucinations in schizophrenia, showing promise in reducing frequency and severity of episodes. The therapy does not address delusions directly but improves overall effect.
Research on hallucinations of musical notation reveals that seven out of eight case studies were gifted musicians. The hallucinations are generally unreadable and seem to be a result of complex perceptual processes. Dr Sacks' findings provide a rich field of study for understanding neural basis of such hallucinations.
Researchers report a significant spike in bath salt-related poisoning incidents, with over 1,700 cases since 2011. The substances' stimulant content can cause violent behavior, hallucinations, and paranoia, highlighting the need for federal regulation.
Research suggests that Frédéric Chopin's hallucinations were probably caused by temporal lobe epilepsy, a condition that can produce brief, fragmentary, and stereotyped visual hallucinations. The authors draw on the composer's own descriptions of his experiences and accounts from friends and pupils to support their claim.
New data from the RECOVER study showed that Neupro (Rotigotine Transdermal System) effectively improved both motor and non-motor symptoms of Parkinson's disease, including sleep quality, mood, cognition, and pain. The treatment also translated into significant improvements in quality of life for patients.
A study of 3,801 young adults found that those who used cannabis for six or more years were twice as likely to develop non-affective psychosis. The longer duration since first cannabis use was associated with higher risk of psychosis-related outcomes.
A recent study found that Iraq and Afghanistan veterans with TBI vision loss have significantly poorer quality of life than comparable civilians. Low-vision patients may also experience vivid visual hallucinations due to Charles Bonnet syndrome, which can be treated by ignoring the images or medication.
A new research study suggests that high caffeine consumption may be linked to a greater tendency to hallucinate. People who consume more than seven cups of instant coffee per day are three times more likely to report hearing voices when there is no one around.
Hallucinations are associated with changes in brain connections and localized activity, highlighting the need for a broader perspective on the condition. The study reveals increased activity in visual brain regions and alterations in connection strength, shedding light on the neural basis of hallucinations.
A new study finds nearly one-third of children in the Pediatric Intensive Care Unit (PICU) experience hallucinations or delusions, which are associated with higher risk of post-traumatic stress symptoms. The study suggests that sedation and physical environment may play a role in reducing these symptoms.
Researchers found structural and functional abnormalities in specific brain regions associated with chronic auditory hallucinations in schizophrenic patients. The study used MRI to identify biological markers for treatment and monitor patient response.
Researchers identified risk factors for hallucinations, sleepiness and swelling in people with early Parkinson's disease, including being male, having multiple health problems and taking certain medications. The study found nearly half of participants developed swelling within four years of treatment.