The study provides a detailed, cross-species view of how tumor-associated dendritic cells are organized and altered in cancer. It identified over 30 distinct dendritic cell subsets and functional states within tumors, with many populations conserved between mice and humans.
Researchers found that HIV-associated protein gp120 increases nerve receptor activity, leading to increased pain sensitivity. Targeting this mechanism with drugs or genetic approaches may alleviate chronic pain associated with HIV, and could also treat other conditions.
The Society of Interventional Radiology has published new practice guidance for the use of prostatic artery embolization (PAE) to treat enlarged prostate. PAE is a minimally invasive treatment that offers men an effective alternative to conventional surgical treatments.
A new study led by Professor Dr. Anne Burmeister found that individuals seeking advice are more likely to reach out when they learn about the benefits for both parties involved, resulting in a 40% increase in contacts and high-quality advice received.
A University of Reading research team is developing a potential treatment for chronic nerve pain using tiny stem cell particles. The RESOLVE project aims to reduce inflammation and reset the processes that drive long-lasting pain, offering a different approach to current treatments.
Proteins lose their hydration shell when environment becomes more acidic, a process that had remained unanswered for 50 years. Direct observation of individual water molecules reveals clear rules: certain amino acids bind or release water, leading to stable inner core regardless of pH level.
A remotely operated AI algorithm has identified the critical view of safety (CVS) in pediatric patients, detecting when all safety criteria were met and issuing real-time alerts. This approach combines AI with teleconferencing for potential new intraoperative guidance without requiring specialized hardware.
Researchers discovered a novel gene BM-SZ that regulates sorghum's cuticular wax accumulation and drought tolerance. The study highlights the gene's essential role in epicuticular wax formation during sorghum evolution.
Researchers at KAIST have developed a new catalyst design technology that can improve the efficiency of key reactions in batteries and fuel cells. By adjusting the electrical environment around the catalyst, they were able to increase the desired reaction by 52%, leading to improved performance, lifespan, and stability.
A new study found that polyopioid use, depression, and persistent pain are strong predictors of suicidal ideation in SCI patients. Researchers urge healthcare providers to screen for suicidal ideation when prescribing multiple opioids or showing signs of misuse.
Applying a magnetic field during catalyst synthesis triples the ammonia yield, making catalytically active sites more accessible. The study demonstrates a scalable strategy for developing next-generation electrocatalysts for efficient and sustainable chemical production.
Researchers decode signaling pathway of atypical chemokine receptor ACKR4, revealing its role in internalizing and degrading unnecessary chemokines. This mechanism helps guide immune cells and regulate inflammation, with potential implications for cancer treatment.
Dr. Martin G. Pomper has been awarded the 2026 Benedict Cassen Prize for his outstanding contributions to nuclear medicine, particularly in the development of PSMA-targeted agents. His work has led to significant advances in cancer diagnosis and treatment, including the creation of commercial PSMA-targeted PET agents.
A recent study by CISPA Helmholtz Center for Information Security examines how users perceive AI labels and their impact on information credibility. The study found that while AI labels can reduce belief in false content, they also trigger skepticism and shape trust more than the content itself.
Research suggests using Chinese rare minnow embryos as an alternative to conventional acute toxicity tests with juvenile fish, reducing animal use and avoiding redundant testing. The study found that embryo-based tests can provide a more sensitive endpoint than lethality alone, highlighting the importance of endpoint selection.
A University of Reading study found that pressure on women to have a natural birth leads to shame and self-blame when expectations are not met. Women reported feeling they had failed as mothers due to medical intervention or complications, highlighting the need for reform in antenatal education.
A randomized clinical trial found that an app-facilitated palliative care intervention maintained health-related quality of life and reduced acute care use. This digital self-management approach also boosted patient self-efficacy.
A new PET radiotracer, 18F-GP1 PET/CT, accurately detects deep vein thrombosis in the legs and reveals lung clot migration. The approach may support faster diagnosis and improve patient care by detecting disease early.
A cohort study found that introducing immunity in US nursing homes was associated with lower overall staffing and staff-to-resident time. During the COVID-19 pandemic, many states adopted immunity from tort liability for harms to nursing home residents.
LGBTQ+ adults over 50 face disparities in health care, mental health, and social connections compared to non-LGBTQ+ peers. They are more likely to experience discrimination and feel isolated from others.
The new feature combines AI-Assisted Data Entry and AI-Assisted CV Import capabilities, allowing researchers and administrators to quickly generate structured records from CVs and unstructured documents. Human-in-the-loop safeguards ensure explicit user review and confirmation before data is applied to a profile.
Researchers developed a new method to raise germ-free zebrafish using gamma irradiation, enabling long-term studies of host-microbe interactions. This approach revealed significant differences between germ-free and intact zebrafish, suggesting conserved roles for microbiomes in immunity and metabolism across species.
Researchers found that traumatic occlusion combined with periodontitis leads to significant bone loss due to upregulated inflammatory pathways. The study suggests that excessive bite force does not directly cause damage but exacerbates existing dysregulation, making clinical applications of occlusal adjustment in treatment more relevant.
A novel solar-thermal desalination process produces fresh water in an energy-efficient way, eliminating brine and chemical additives. The technology leverages the 'coffee ring' effect to extract salts from seawater, producing nearly 100% of the salts in solid form.
Researchers discovered curcumin's ability to stabilize microscopic ceramic parts by physically screening stray light and neutralizing erratic energy sparks. This approach enables the production of complex, ultra-lightweight components for advanced technologies.
Researchers developed an AI-enabled method, RivDepth, to map river depth in complex environments. The model combines satellite spectral information with suspended sediment concentration proxies, capturing water depth and reflectance patterns with high accuracy.
Researchers developed a nanocomposite coating that improves stainless steel's resistance to highly acidic conditions, offering a potential solution for industries with metal equipment exposed to aggressive chemicals. The coating delivered up to 98.2% corrosion inhibition efficiency and remained stable over seven days of immersion.
Dr. Owen Carmichael received the James W. and Neil Ann Parks Professorship for Dementia Research, Prevention and Treatment at Pennington Biomedical. His work focuses on developing advanced biomedical imaging techniques to better understand Alzheimer's disease and brain aging.
Research on box jellyfish reveals complex reproductive traits and strategies, shedding light on their life cycles and ecological role. Understanding these processes can improve predictions of jellyfish occurrences and inform management efforts.
A recent study published in Depression and Anxiety found that moderate-to-vigorous physical activity and sufficient sleep are crucial for protecting mental health in middle age. Replacing sedentary behavior with light activity produced smaller benefits compared to moderate-to-vigorous physical activity, highlighting the importance of i...
A qualitative study in Norway finds that seashore play is key to fostering emergent ocean literacy in early childhood education for sustainability. The research highlights the importance of collaborative exploration, relationships, and play in supporting environmental awareness.
A UNIGE team studied the evolutionary history of plant mechanisms that protect against UV-B radiation in Marchantia polymorpha. They found that while the core mechanism is conserved, regulatory proteins play different roles in ancestral and modern plants, influencing their tolerance to light stress.
The research team developed a technology that directly forms a junction structure within a 2D semiconductor using a laser to enhance photodetection performance. The resulting energy barrier rapidly separates the positively and negatively charged carriers generated by light, suppressing their recombination.
Researchers developed technology to analyze electroencephalogram (EEG) signals triggered by thermal stimuli, classifying pain intensity objectively. The AI model reduces bias in subjective self-reported labels, improving performance compared to conventional models.
A large study found significant genetic similarities between gestational diabetes and type 2 diabetes, with 37 genetic variants associated with gestational diabetes. The research also suggests that genetic effects may differ across populations, offering new insights into the underlying causes of these conditions.
A clinical trial found that low-dose quetiapine improved sleep quality and reduced obstructive sleep apnea severity, but significantly impaired alertness and driving performance. The study highlights the need for caution when using sedating medications for insomnia in people with known or possible sleep apnea.
A University of Michigan research team is exploring the development of knee exoskeletons to reduce joint contact forces and relieve osteoarthritis pain. Preliminary testing suggests that these orthotic brace-based exos and drone-style motors could provide significant relief.
A research team proposes the Metacognitive Laziness Scale (MLS) to measure students' tendency to delegate metacognitive tasks to AI systems. The study found significant positive associations between metacognitive laziness and disaffection with learning, suggesting that excessive reliance on AI may undermine academic achievement.
Researchers from six Asian countries have launched a coordinated effort to create an artificial single-celled biological system. The 10-year roadmap aims to develop stable phospholipid vesicles with minimal genomes, endogenous synthesis of key metabolites, and true self-replication.
A new study suggests that a strengthened and southward-shifted westerly jet may partly offset drying in Asian drylands. The research found that the Eurasian Subtropical Westerly Jet is projected to strengthen and shift southward during summer, enhancing moisture advection into Central Asia.
A new study analyzes 240 health care AI-related policies, finding accelerated oversight efforts but a lack of unified framework for clinical AI deployment. Governance challenges are emerging as AI adoption accelerates, requiring strong oversight and internal governance structures.
Researchers at DGIST developed Laser-Assisted Microlens Array Processing to create precise defects in 2D semiconductors. This technology resulted in a 63-fold increase in on-current and 51-fold improvement in field-effect mobility, making it suitable for next-gen ultra-compact semiconductors.
The DFG is establishing 13 new Collaborative Research Centres to support innovative and long-term research projects. The CRCs will focus on topics such as mechanophores, bone tissue remodelling, planetary habitability, and food system diversification.
Researchers developed a defect-rich catalyst that guides phenol through a direct oxidative transfer process, converting it into polymeric products on the catalyst surface. The study shows controlled polymerization while maintaining high removal efficiency and stability.
Research from Harvard Medical School confirms pediatric flu vaccines effectively reduce childhood flu cases, with fall-born children being more likely vaccinated and less likely to catch the flu. The study's findings provide additional support for flu vaccination, highlighting its public health benefits.
The study found high-risk associations between alcohol use and all ten cancers examined, with risk increasing progressively as intake rose. Low-to-moderate drinking was associated with lower disease risk for type 2 diabetes, Alzheimer's disease, ischemic heart disease, and stroke.
Researchers highlight latest developments in pathology, diagnosis, and treatment of MASLD and IPFD, revealing correlations with chronic diseases like liver cancer and pancreatic cancer. Innovative treatments, such as AI-driven approaches and organ-targeted therapies, show promise for precision prevention and therapy.
A European research team is developing bacteria that can produce important chemical base materials from sustainable methanol, aiming to replace fossil resources in the chemical industry. The goal is to make chemical production more sustainable without jeopardizing food security.
A University of Utah team developed a smartwatch prototype that tracks blood pressure and flow using electrical properties of blood flow for continuous, cuff-free readings. The technology harnesses physics and machine learning to provide accurate and interpretable results.
Kobe University researchers clarify conditions under which the planar Hall effect appears in classical materials, revealing threefold symmetry and mirror symmetry. This breakthrough enhances diagnostic tools for quantum computing and spintronics applications.
A nationally representative survey of US adolescents and young adults found that a fifth used AI chatbots for mental health advice. Proactive discussion with parents and clinicians about chatbot use is necessary to promote safety and linkages to evidence-based care.
Researchers found that condensing into droplets optimizes biochemical conditions for kinases to catalyze reactions and activate cell signaling pathways. This phenomenon helps control growth signals and could lead to new strategies for cancer drug development by interfering with the ability of enzymes to form droplets.
The Pan European One Health Network will harmonise the European response to infectious diseases by integrating human, animal, and environmental health. The network aims to develop a coordinated preventative response through collaborative innovation and knowledge sharing.
Researchers developed a system integrating convolutional neural networks and all-optical passive diffractive decoders for super-resolution image projection. The hybrid platform achieved significant improvements in image synthesis over extended depth, reducing data requirements without additional power constraints.
Researchers identified microRNA-25 as a key player in creating an immune-suppressive tumor environment that resists cancer immunotherapy. Removing miR-25 reshaped the environment and activated anti-tumor immune responses, suggesting a potential target for converting 'cold' tumors into responsive 'hot' tumors.
SwRI has introduced a new 30-inch diameter pressure vessel, enabling faster testing of larger equipment at extreme ocean depths. The vessel can test equipment up to 16,500 psig, simulating the pressures in the deepest parts of the ocean, and features a novel quick-acting closure system.
The journal is seeking articles that explore the transformative power of digital tools to improve safety and health outcomes in occupational settings. Submissions focus on applying mHealth, wearable sensors, and real-time analytics to monitor physical hazards and reduce ergonomic strain.
Researchers found that 66.6% of gene expression changes are linked to e-cigarette flavor and device type, while only 28.8% relate to vaping frequency or amount. The study suggests that each flavor has unique biological effects.
The American Heart Association will bring its Nation of Lifesavers mobile CPR unit to FIFA Fan Festivals in four US host cities, offering Hands-Only CPR instruction to thousands of people. This initiative aims to increase community preparedness and survival rates by empowering more people to act in cardiac emergencies.
A new digital platform has lowered the cost of GLP-1 medications, making them more accessible to patients without insurance. However, sustaining treatment remains a challenge due to the cash-pay model's lack of financial protection for indefinite treatment.