A low-calorie ketogenic diet has been found to increase total testosterone and sex hormone (SHBG) levels in overweight men. After four weeks on the diet, body weight, fat mass, and BMI decreased significantly, while testosterone and SHBG levels substantially increased.
A 23-year study found strong links between gestational diabetes during pregnancy and the development of type-1 and type-2 diabetes later in life. Women who experienced gestational diabetes were more prone to developing these conditions, highlighting the importance of autoantibody testing for risk assessment.
A new study suggests that night shift work is associated with menstrual irregularity and an increased risk of developing endometriosis. Researchers found altered expressions of core clock genes in ectopic and eutopic endometrial tissues, indicating a disturbance of biological timing.
The European Society of Endocrinology has confirmed the strong links between hormones and COVID-19, with evidence suggesting an 'endocrine phenotype' of the disease. Diabetes and obesity have emerged as comorbidities associated with severity and mortality of COVID-19.
A new study published in The Lancet Diabetes & Endocrinology found that BMI cut-offs used by the World Health Organization and UK's National Institute for Health and Care Excellence are not suitable for adults from Black Asian and Minority Ethnic backgrounds. The research, which included over 1.5 million people, shows that these groups...
A mouse study found that vitamin D deficiency impairs skeletal muscle mitochondrial function, leading to reduced energy production and potentially poor muscle strength. The study suggests that preventing vitamin D deficiency in older adults could help maintain better muscle function and reduce age-related muscle deterioration.
A study published in the Journal of Endocrinology found an association between higher body weight and greater menstrual blood loss, potentially due to delayed womb lining repair. The research used a combined approach of human and mouse studies, suggesting obesity may contribute to heavier periods through increased inflammation.
Endocrinology clinics see many patients needing long-term close follow-up, with most feeling telehealth visits are comparable in quality to in-person visits. Providers prefer video visits due to lack of physical examination component in phone calls.
A recent study published in The Journal of Clinical Endocrinology & Metabolism found that non-Hispanic black patients with Type 1 diabetes and COVID-19 are almost four times as likely to present with diabetic ketoacidosis compared to white patients. The study highlights the importance of addressing social determinants of health, includ...
A study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism found that girls with excess body fat developed fully mature breasts more slowly but started their period sooner. The researchers also found higher levels of reproductive hormones, including testosterone, in girls with obesity.
Researchers found that hospitalized COVID-19 patients with low sodium levels are twice as likely to need intubation or advanced breathing support, while those with high sodium levels are three times more likely to die. Sodium measurements can inform doctors about which patients are at high risk of deterioration and death.
A new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism found that Chinese adults are more likely to face high blood pressure and other health risks as a result of higher body mass index (BMI) and waist circumference. The research analyzed data from over 126,000 participants and discovered that C...
A recent study published in the Journal of Clinical Endocrinology & Metabolism highlights the need to address health disparities in diabetes by examining systemic racism and its impact on social conditions. The authors recommend implementing culturally and linguistically appropriate services, unconscious bias training, and value divers...
A recent study published in Nature Reviews Endocrinology highlights the interconnection between obesity, impaired metabolic health, and COVID-19 severity. The research found that obesity, visceral fatness, and impaired metabolic health are significant risk factors for a more severe course of COVID-19.
A new study found that gut microbes can affect bone mass and structure in mice, with treatments altering the gut microbiome potentially aiding healthy skeletal growth. The findings suggest that microbes can be inherited or transmitted between individuals and impact skeletal development.
A new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism uses machine learning to predict gestational diabetes in Chinese women. The researchers analyzed nearly 17,000 electronic health records and found that low body mass was associated with an increased risk of gestational diabetes.
A new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism found that gastric bypass surgery can lead to long-term diabetes remission in over half of adults with type 2 diabetes. The study suggests that weight loss is not the only factor contributing to improved blood sugar levels.
A new University of Warwick-led study found that obese patients over 60 years old can lose an equivalent amount of weight as younger people through lifestyle changes alone. The research aims to correct misconceptions about the effectiveness of weight loss in older people and promote healthy ageing.
The Hormones: The Inside Story podcast series explores the facts behind hormones and their impact on daily life, sleep, stress, body fat, fertility, and more. It cuts through myths and misinformation with expert-led science, empowering listeners to make informed decisions about their health.
The Endocrine Society's virtual annual meeting, ENDO 2021, offers journalists the opportunity to discuss groundbreaking research with world-renowned experts in diverse fields. The event features over 70 live sessions, 20 oral sessions, and six plenaries, covering topics such as diabetes, obesity, reproductive health, and more.
A new study finds that a drug called MVT-602 can improve fertility in women with reproductive health problems by targeting the kisspeptin hormone system. The drug's longer duration of action allows for less frequent dosing, offering improved treatment options for conditions such as polycystic ovary syndrome and hypothalamic amenorrhea.
A recent study published in the Journal of Clinical Endocrinology & Metabolism reveals that COVID-19 patients with vertebral fractures are twice as likely to die from the disease. The researchers found a significant association between vertebral fractures and severe disease outcomes, including increased need for ventilators.
Researchers found that cold temperatures increase vitamin A levels, stimulating the conversion of white into brown adipose tissue and enhancing fat burning. This 'fat transformation' is a potential approach for novel obesity therapeutics.
Researchers have identified phosphorus-containing compounds as markers for thyroid hormone action in tissue using non-invasive magnetic resonance spectroscopy. This allows for the measurement of hormone action in different areas of the body, potentially improving care for patients with thyroid dysfunction.
The COVID-19 pandemic has accelerated adoption of innovative diabetes care models, including telehealth, to improve medical outcomes and patient experience. Despite challenges such as lack of insurance coverage and workforce shortages, these models have the potential to transform diabetes care for millions worldwide.
Researchers found that supplementing people with HIV with GlyNAC, a combination of glycine and N-acetylcysteine, improves multiple deficits associated with premature aging. The supplement boosts glutathione levels, a natural antioxidant that neutralizes free radicals and helps maintain cellular function.
People with underlying endocrine diseases are at higher risk of developing severe COVID-19 and experiencing worse outcomes. COVID-19 is also associated with long-term effects on the hormone system, including weight loss and muscle mass loss.
The joint Clinical Practice Guidelines program aims to provide evidence-based recommendations for clinical care, addressing global differences in access to diagnostic tools and therapies. The guidelines will support better patient care, improved health outcomes, increased patient safety, and controlled healthcare costs.
The European Society of Endocrinology reviews evidence on hormone involvement in COVID-19 infection, disease severity, and treatment. Obesity, cardiovascular disease, and sex hormones are identified as risk factors.
A new artificial pancreas system has been shown to prevent hypoglycemia during and after heavy exercise in people with type 1 diabetes. The study, published in the Journal of Clinical Endocrinology & Metabolism, found that the system performed well and was safe compared to standard therapy.
The International Osteoporosis Foundation's Skeletal Rare Diseases Academy Awards recognized five young researchers for their high-quality research on rare disorders of the skeleton. The winners received a certificate and grant, valued at $1000, in recognition of their outstanding contributions.
Three experts, Professor Maria-Luisa Brandi, Dr. Lee Joon-Kiong, and Professor Ego Seeman, have been awarded the IOF President's Award for their contributions to osteoporosis research, education, and public awareness. The award recognizes their efforts to expand the Foundation's programs and outreach in the scientific and policy spheres.
A new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism highlights the impact of anorexia nervosa on young women's growth. The research found that girls with anorexia nervosa tend to have stunted growth, which may affect their overall health and well-being.
A high fructose diet in pregnant women can alter the metabolism of their offspring, researchers found. The study, published in Frontiers in Endocrinology, showed that fructose intake before and during pregnancy led to significant changes in maternal metabolic function and milk composition.
Researchers developed an algorithm to monitor high blood sugar in COVID-19 patients, reducing secondary infections and kidney issues. The tool identifies risk categories based on hyperglycemia severity, insulin resistance and inflammatory markers.
A new study from the University of Colorado Anschutz Medical Campus finds that peer mentorship groups are better suited for fostering success among underrepresented groups. These groups provide flexible support and can be established online, making them an ideal option during the COVID-19 pandemic.
An international team identified an error in the cytochrome P450 oxidoreductase (POR) gene as the cause of aromatase deficiency, a rare metabolic disorder. This discovery enables precise therapy and prevents side effects associated with steroid supplementation.
A new study published in The Lancet Diabetes & Endocrinology found that COVID-19 patients with extremely high cortisol levels are more likely to deteriorate quickly and die. Cortisol levels can be used as a marker of illness severity, helping identify patients who need intensive care.
A new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism found that up to one in five women with a history of miscarriage or subfertility have mild thyroid dysfunction. Detecting thyroid abnormalities prior to conception may improve pregnancy outcomes for these women.
The study shows that the FreeStyle Libre 14 day system is estimated to save roughly 50% in average costs associated with severe hypoglycemia for people with type 1 and type 2 diabetes. Annual cost savings are 61% and 63% lower compared to traditional fingerstick testing.
A new study published in the Journal of Clinical Endocrinology & Metabolism found that PFAS exposure may cause menopause to occur two years earlier in women. High levels of PFAS were associated with an increased risk of early menopause, which could have significant impacts on cardiovascular and bone health.
A new study by Mount Sinai researchers found that insulin resistance is a key factor mediating racial disparities in breast cancer prognosis. Black women with invasive breast cancer had higher rates of insulin resistance and more aggressive tumors than white women.
A study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism found that short-term cold exposure increased energy expenditure and improved fatty acid profiles in individuals with active brown fat. People with brown fat burned 15% more calories than those without, highlighting the organ's potential as a ta...
A recent study found that technology use by adults with type 1 diabetes is lower among African-American and Hispanic patients. The use of continuous glucose monitors (CGM) and continuous subcutaneous insulin infusion (CSII) devices was significantly lower in these groups, highlighting racial disparities in access to healthcare.
Dr. Stephanie Roberts receives the SPR Bridging to Success Award for supporting transitioning pediatric physician-scientists. Her research focuses on understanding genetic variants affecting pubertal onset and reproductive disorders.
A high sugar diet during pregnancy can lead to increased progesterone levels and changes in dopamine function, which may affect mother-pup interaction and long-term mental health. The study suggests that limiting added sugars to 5-10% of daily calories may have benefits for metabolic and hormone health.
A new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism found that eating a large breakfast instead of a large dinner creates twice as high diet-induced thermogenesis. This process measures how well metabolism is working, and can differ depending on mealtime.
Research published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism found that teens with obesity and PCOS have an altered gut microbiome compared to those without the condition. This altered microbiome is associated with higher testosterone levels, metabolic complications, and other health risks.
A 15-year study found that dysfunctional pancreatic beta-cells, independent of body weight, are the earliest event leading to pre-diabetes in children. The study also linked this condition to genetic factors associated with type 2 diabetes in adults.
Research published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism found that older adults with hypothyroidism are 26% more likely to die from all causes than their peers without the condition. However, this increased risk was not observed in individuals with milder forms of thyroid disease.
Recent study suggests a modest association between radioiodine treatment for hyperthyroidism and increased risk of solid cancer, including breast cancer. The Society for Endocrinology and British Thyroid Association advise caution in interpreting the findings and highlight the need for further research.
Dr. Mone Zaidi has been recognized as an AAAS Fellow for his groundbreaking research on pituitary-metabolic circuits and their impact on body fat, bone mass, and energy metabolism. His work holds strong clinical potential for treating osteoporosis.
A study published in Scientific Reports reveals the dopamine D2 receptor plays a crucial role in modulating Wnt expression and controlling cell proliferation, which may lead to new therapeutics for nephrology, endocrinology, and psychiatry. The findings also have implications for the development of precision medicine.
A study by Mount Sinai researchers found that more than half of patients taking ruxolitinib gained over 5% in body weight, associated with increased systolic blood pressure and liver enzymes. The study highlights the need for physicians to counsel patients about potential metabolic effects.
A study published by Professor Henrik Oster suggests that daily stress coupled with a disrupted internal clock increases the risk of developing metabolic disorders such as obesity and type 2 diabetes. This is because environmental stress can affect food intake, promote weight gain, and have long-lasting effects on stress responses.
Researchers identify potential environmental risk factors and new treatment strategies for triple negative breast cancer (TNBC), an aggressive form of breast cancer. The study suggests that exposure to common chemicals may increase the risk of developing TNBC, and highlights the potential for combination therapy as a treatment option.
Researchers found that healthy men taking commonly prescribed doses of glucocorticoids for a short period experienced changes in blood sugar metabolism, associated with an increased risk of developing diabetes. The study highlights the need for medical professionals to consider and monitor potential side effects.
Pregnant women with low vitamin B12 levels experience increased fat production and reduced breakdown, predisposing them to obesity. A recent study found that vitamin B12 deficiency impairs fat cell metabolism, leading to increased inflammation and impaired metabolic function.
A new study reveals that bariatric surgery can lead to successful weight loss and better diabetes control in older adults. After two years, the patients had lost an average of 24% of their body weight and seen a significant reduction in HbA1c levels. The study suggests that age alone should not be considered a contraindication to baria...
Research suggests that impaired liver function during pregnancy can lead to altered gut bacteria composition in children, increasing the risk of obesity. Maintaining a healthy diet and targeting gut microbiome composition with pre-biotics or pro-biotics may help prevent childhood obesity.