Developmental Disabilities
Articles tagged with Developmental Disabilities
New AI tool developed by Stowers Institute and Helmholtz Munich scientists predicts how cells choose their future — helping uncover hidden drivers of development
Researchers developed RegVelo, an AI framework that models cellular dynamics and gene regulation to predict cellular fate decisions. The model traces developmental trajectories and simulates regulatory interactions, providing insights into hidden drivers of development and potential therapeutic targets.
What factors might account for the increased risk of autism in children with epilepsy?
A large population-based study found that children with epilepsy have a significantly higher risk of also having autism spectrum disorder. The study highlighted key differences between children with co-occurring conditions, including intellectual disability and age of diagnosis.
Stereotypes of autism in TV and film may be linked to delayed diagnosis, Stirling study finds
Researchers found that portrayals in media lacked diversity, often focusing on white, socially awkward male characters. Autistic participants felt that such portrayals were exaggerated and simplified, limiting public understanding and self-understanding.
The boy on the balcony who never came outside
Dr. Dilek Colak's journey began with a childhood observation of a boy with mental illness, which inspired her to pursue a career in neuroscience. Her current work focuses on understanding autism and schizophrenia through the study of human brain organoids.
Toxic PCBs, sex-biased genes, and the developing brain
Researchers at the UC Davis MIND Institute found that polychlorinated biphenyls (PCBs) alter genes more in females than males, with a key gene called XIST playing a protective role. Folic acid also shows promise in mitigating harmful effects of PCB exposure, particularly in women.
Can wearable technology detect the earliest signs of autism in infants? New study seeks to find out
Researchers are developing a new wearable technology to monitor babies' movements and detect early signs of autism. The study aims to improve early identification and intervention, which is crucial for optimal developmental outcomes in autistic individuals.
New genetic insights into developmental dysplasia of the hip
A large multiethnic study identifies genetic factors associated with developmental dysplasia of the hip (DDH) and its progression to osteoarthritis of the hip. Variations in COL11A2, CALN1, and TRPM7 genes were found to be common to both DDH and hip OA.
Study suggests link between prenatal exposure to certain medications and increased autism risk
A landmark study found a significant association between prenatal prescription of sterol biosynthesis-inhibiting medications and the risk of autism spectrum disorder (ASD) in children. The research identified commonly prescribed medications as potential contributors to neurodevelopmental vulnerability.
AI models lean on autism stereotypes when giving social advice, new study finds
Artificial intelligence models provide personalized advice, but may perpetuate negative stereotypes about people with autism. Researchers found that up to 70% of the time, AI discourages those with autism from socializing.
Scientists engineer a tool to “edit” brain circuits and enhance memory
Researchers develop molecular tool called SynTrogo, which enables selective dismantling of synaptic connections in brain circuits. By harnessing astrocytes, the system reduces synapse number while strengthening remaining connections, leading to enhanced long-term potentiation and improved memory.
Survey: Americans strongly support autism research — but most don’t know brain donation is needed to advance it
A new survey by Autism BrainNet reveals a significant disconnect between Americans' strong support for autism research and their limited understanding of postmortem brain donation. The survey found that 70% of respondents had never heard of brain donation, despite 92% agreeing its importance in advancing research.
Researchers identify the most common recessive neurodevelopmental disorder ever discovered
The study identified a previously unknown recessive neurodevelopmental disorder caused by changes in the RNU2-2 gene, affecting thousands of individuals in the US. Symptoms vary widely, including developmental delays, limited speech, and seizures, and may be more common than previously thought.
Video training helps young adults with disabilities navigate romance
Researchers developed a video modeling program to enhance romantic relationship skills in young adults with intellectual and developmental disabilities. The study found that participants significantly improved their decision-making skills across four relationship domains, averaging 76% accuracy after the intervention. The findings high...
SynGAP Research Fund (SRF) announces formal transition to CURE SYNGAP1, reinforcing commitment to treatment development
CURE SYNGAP1 accelerates treatment development for SYNGAP1-Related Disorders through rigorous research and family-led leadership. The organization has funded over $8 million in grants and identified over 1,707 patients to date.
TikTok’s mental health ‘minefield’
A systematic review of social media platforms reveals that TikTok contains a substantial proportion of misleading information about mental health and neurodivergence, with higher rates of misinformation than other platforms. The study emphasizes the importance of credible sources and evidence-based content to combat spreading false ide...
Augmented reality job coaching boosts performance by 79% for people with disabilities
A new study found that augmented reality job coaching significantly improves job performance for individuals with intellectual and developmental disabilities. The AR-based application delivered real-time guidance, enabling participants to complete complex tasks with minimal external support. This innovative approach has the potential t...
Online spaces can provide bodily comfort, relief and inclusion for some autistic people, study says
Online spaces provide bodily comfort, relief, and inclusion for some autistic adults, allowing them to express themselves and connect genuinely without scrutiny. This challenges the assumption that in-person interaction is always more valuable.
Teachers report limited or no training to support neurodivergent pupils, new study finds
A new study found that nearly 25% of UK teachers received no training on supporting neurodivergent pupils, with most reporting brief and limited sessions. The researchers highlight a mismatch between the complexity of pupils' needs and the training teachers are currently receiving.
Georgia State experts to help lead landmark study of profound autism
Researchers from Georgia State University, Marcus Autism Center and Emory University are collaborating to investigate the causes of profound autism in children. The 7,500 child study will explore patterns in development, behavior, brain activity and genetics to find more effective therapies.
Anxiety, depression, and care barriers in adults with intellectual and developmental disabilities
This cross-sectional study highlights critical gaps in accessible mental health services for adults with intellectual and developmental disabilities. The findings underscore the need for policy reforms to address systemic inequities and provide disability-informed care.
Study: Anxiety, gloom often accompany intellectual deficits
A study analyzing data from 44,000 adults found that those with intellectual and developmental disabilities experience substantially higher rates of anxiety and depression. The study also highlights significant healthcare treatment and access barriers facing this population.
Babies with an increased likelihood of autism may struggle to settle into deep, restorative sleep, according to a new study from the University of East Anglia.
A new study from the University of East Anglia found that babies with an increased likelihood of autism may struggle to settle into deep, restorative sleep. Those with high sensory sensitivity slept more lightly even in quiet environments.
Does the motion of our DNA influence its activity?
Exposure to intense wildfire smoke during pregnancy may be linked to increased likelihood of autism
Researchers found strongest associations on very smoky days and in areas with cleaner air overall. The study of over 8.6 million births in California suggests that intense wildfire smoke exposure may increase the likelihood of autism in children.
As nights warm, study flags possible prenatal link to autism risk
A new study found that warmer nighttime temperatures during pregnancy may be associated with a higher risk of autism diagnosis in children. Exposure to extreme heat during early and late pregnancy increased the risk by 15% and 13%, respectively.
No association between mRNA COVID-19 vaccination during pregnancy and autism in children, new research shows
Researchers studied 434 children for signs of autism or neurodevelopmental problems, finding no link between mRNA vaccine and autism. The study suggests that COVID-19 vaccines are safe to receive during pregnancy to protect maternal and infant health.
New study calls for faster autism diagnosis to prevent suicides
A new study by Bournemouth University calls for faster autism diagnosis and tailored mental health support to reduce autistic people's suicidal thoughts and attempts. The research identified key priorities, including improving autism diagnostic services, tackling societal inequalities, and providing autism-specific support in crisis.
Dr. Paul Donlin-Asp of the University of Edinburgh to dissect the molecular functions and regulation of local SYNGAP1 protein synthesis with support from CURE SYNGAP1 (fka SynGAP Research Fund)
Dr. Paul Donlin-Asp will investigate the molecular functions and regulation of local SYNGAP1 protein synthesis, aiming to advance therapies for SYNGAP1-related Disorders. The project seeks to map mechanisms controlling SYNGAP1 protein production in neurons.
University of Houston study offers potential new targets to identify, remediate dyslexia
A University of Houston study challenges traditional views on dyslexia, suggesting it stems from an overall brain network vulnerability. The research identified two developmental origins: one related to brain architecture and another to synaptic signaling, which may be uniquely human.
Federation of European Neuroscience Societies Forum 2026, 6-10 July, Barcelona, Spain
The FENS Forum 2026 will be Europe's largest neuroscience congress, covering areas of basic to translational research. Journalists can register for free and attend symposia and poster sessions.
Study maps how varied genetic forms of autism lead to common features
Researchers created a comprehensive map showing how eight different genetic mutations associated with autism spectrum disorder affect early brain development. They found that despite initial differences, these mutations increasingly impact overlapping molecular pathways as development progresses.
Exposure to wildfire smoke late in pregnancy may raise autism risk in children
A new study published in Environmental Science & Technology found that exposure to wildfire smoke during the third trimester may raise the risk of autism diagnoses in children. Mothers who were exposed to more than 10 days of wildfire smoke had a 23% higher risk of their child being diagnosed with autism by age 5.
Autistic and non-autistic faces may “speak a different language” when expressing emotion
Researchers found that autistic and non-autistic individuals produce distinct emotional facial expressions, with autistic adults exhibiting more unique and complex expressions. The study suggests that these differences in facial expressions may contribute to difficulties in recognizing each other's emotions.
Taking paracetamol during pregnancy does not increase risk of autism, ADHD or intellectual disabilities
A systematic review and meta-analysis of 43 studies found no link between paracetamol use during pregnancy and increased risks of autism, ADHD, or intellectual disabilities. Researchers concluded that previously reported links may be due to genetic predisposition or maternal factors rather than the medication itself.
Autism research reframed: Why heterogeneity is the data, not the noise
Dr. Noritaka Ichinohe challenges the long-held assumption that averaging away individual differences is necessary in psychiatric research. Instead, biological heterogeneity is seen as a phenomenon demanding explanation. The author's work on primate brain mapping and molecular subtyping has identified convergence points between species ...
January 2026 issues of APA journals feature new research on autism, pediatric anxiety, psychedelic therapy, suicide prevention and more
The January 2026 issues of four American Psychiatric Association journals feature groundbreaking research on externalizing disorders, pediatric anxiety, autism, and inflammation-related depression. The studies also explore the potential benefits of psychedelic therapy in suicide prevention.
Why neurodiversity might be the hidden engine of entrepreneurial success
Researchers found that ADHD enables high entrepreneurial alertness and risk-taking, while dyslexia fosters advanced delegation strategies. Bipolar traits correlate with creativity and a willingness to pursue bold ventures. The study advocates for business environments that value neurodiverse strengths, rather than seeking normalcy.
Three-hit model describes the causes of autism
A new study describes a three-hit metabolic signaling model that reframes autism as a treatable disorder of cellular communication and energy metabolism. The model suggests that up to half of all autism cases might be prevented or reduced with prenatal and early-life interventions.
Treating adults with autism: Maryland Clinical Center offers national blueprint for care after pediatric transition
A new report from the University of Maryland School of Medicine presents a five-year data model demonstrating how a state-funded, multidisciplinary care approach can improve health outcomes and quality of life for adults with autism spectrum disorder (ASD) and other neurodevelopmental disorders. The study found that this model can serv...
Study explores the link between newspaper preference and attitudes towards autism
A new study from City St George's University of London found that people's newspaper reading habits are a reliable predictor of their attitudes towards autism. The research reveals that around 10% of the differences in automatic, unconscious bias were linked to what newspapers people read.
Rise in ADHD diagnoses can leave parents confused about ‘typical’ behavior for kids
A new book by experts highlights how the prevalence of ADHD and autism spectrum disorder has increased, but suggests it may not be due to a genuine increase in cases. The authors argue that 'typical' behavior can vary greatly among children, and that acceptance and understanding of individuality is key.
What can the US learn from Europe when it comes to the provision of cell and gene therapy?
The US needs a new strategy for insurance coverage and access to cell and gene therapies due to high up-front costs. In contrast, Europe has approved 19 CGTs with most being reimbursed within two years of approval based on demonstrated added therapeutic value.
New EndoCompass Research Roadmap calls for coordinated investment to tackle Europe’s hormone health challenge
The European Society of Endocrinology has released the EndoCompass Research Roadmap, a major new initiative to align research efforts and improve funding strategies for hormone-related health challenges. The roadmap identifies specific research needs across eight endocrine specialties and five cross-cutting areas.
Child neurologists can play a critical role in identifying movement issues in autism, but more training is needed
A new study found that child neurologists often lack knowledge and education on motor difficulties in children with autism. Motor impairments are common in autistic children, affecting their development, language skills, and social interactions. The study recommends more training for medical students and residents to recognize and addr...
Implicit bias impacts how autistic and non-autistic people exert ‘charitable’ effort
A new study found that implicit biases impact how much effort individuals, both autistic and non-autistic, put into charitable behaviors. While explicit biases were not a factor, participants showed self-bias in decisions, prioritizing their own efforts over others.
Background genetic variants influence clinical features in complex disorders
A recent study found that a person's genetic background, rather than a single gene, plays a key role in the development of complex disorders. The research revealed patterns of secondary variants that can modify the impact of primary genetic variants on clinical outcomes.
University of Cincinnati researcher receives first NIH K grant in College of Allied Health Sciences
Andrea Ford's research aims to support preschoolers with autism by adapting the Extensions of Community Health Outcomes (ECHO) model. She plans to engage educators and caregivers in mixed-methods research and build a community of practice to shape the model and provide professional development opportunities.
Study reveals genetic and developmental differences in people with earlier versus later autism diagnosis
Researchers found distinct genetic profiles for early- and late-diagnosed autism, with earlier diagnosed groups showing more social interaction difficulties in infancy and behavioral problems in adolescence. Later diagnosed individuals experienced increased social and behavioral difficulties during adolescence and higher rates of menta...
Gesticulating while speaking is key in improving comprehension in children with developmental language disorders
A study by Universitat Oberta de Catalunya researchers found that gestures and speech rhythms are key to helping children with DLD comprehend oral language. Intonation and head inclination can facilitate understanding of complex meanings, particularly in children with language difficulties.
AI model offers accurate and explainable insights to support autism assessment
A deep learning model achieved up to 98% accuracy in distinguishing autistic from neurotypical participants, providing clear insights into brain regions most influential to its decisions. The model could benefit autistic people and clinicians by offering accurate and explainable results to inform assessment and support.
Landmark genetic study sheds new light on how the eye develops its sharpest vision
Researchers have identified over 120 genetic signals shaping foveal development, including pathways involved in vitamin A metabolism and retinal cell fate. The study provides the first comprehensive genetic dissection of human foveal pit architecture, revealing new insights into childhood visual disorders.
Researchers reveal how autism-linked mutation triggers PTSD-like fear
A study published in Science Advances reveals that an autism-linked mutation disrupts brain circuits responsible for erasing fear memories, leading to PTSD-like symptoms. By reactivating specific neurons, researchers were able to reverse the behavioral and physiological abnormalities.
Autistic children more likely to experience persistent stomach problems
A new study published in Autism found that autistic children are more likely to experience ongoing gastrointestinal problems than their typically developing peers. These symptoms can affect sleep, communication, sensory processing and behavior, and often don't have an identified medical cause.
Placental research may transform our understanding of autism and human brain evolution
Dr. Alex Tsompanidis proposes placental hormone production shaped human cognitive capabilities, redefining autism origins and neurodiversity. His research could lead to screening protocols and support for children with developmental differences.
First discovery of how an autism-linked mutation reduces vasopressin and alters social behavior
Scientists have identified the mechanism linking a mutation in the Shank3 gene with alterations in social behavior, revealing that vasopressin plays a crucial role in regulating sociability and aggression. The study shows that targeting specific vasopressin receptors can restore social abilities without affecting aggression.
Diana Schendel named Editor-in-Chief of Autism Research
Diana Schendel assumes leadership of Autism Research journal with expertise in epidemiology and global autism research leadership. She aims to publish high-quality, impactful research from around the world.
Industrial pollution’s imprint lasts generations
Researchers found a strong correlation between industrial pollution exposure during pregnancy and the risk of intellectual disabilities in grandchildren. A study using Utah Population Database data revealed that grandmothers' prenatal exposures can increase the risk of intellectual disabilities in their grandchildren's children.
Gut–immune–brain axis modulation of autism spectrum disorder using precision-selected probiotics
Researchers discovered a multi-faceted mechanism behind ASD, revealing the gut microbiota and host immune system's influence on disease progression. Precision-selected probiotics restored metabolic balance, reduced neuroinflammation, and ameliorated behavioral abnormalities in ASD mouse models.
UH expands behavioral health programs to meet workforce demand
The University of Houston is expanding its behavioral health offerings with new ABA training programs, addressing growing need for behavior analysts. Salaries range from $63,000-$77,000 annually, with autism diagnoses on the rise due to improved screenings and assessments.