Articles tagged with Orthopedics
Researchers developed a multi-functional biomaterial that eradicates residual cancer cells, prevents bacterial colonization, and regenerates missing bone tissue. Gallium oxide selectively targets bone cancer cells overexpressing transferrin receptors, causing cell death, while preventing infection in surgical sites.
Spine surgeons find 3D-printed models helpful for complex cases, enabling better understanding of anatomical variations. The technology facilitates improved patient communication, with tangible models allowing physicians to explain procedures in detail.
Researchers have identified a key muscle hormone, musclin, that helps clear dead cells and treat periprosthetic joint infections. Musclin triggers macrophage metabolism shifts, boosting efferocytosis capacity and breaking the cycle of inflammation.
A study of 4,967 community-dwelling adults aged 60+ found that being female, polypharmacy, and unintentional weight loss are associated with fragility fractures. Physical activity was not significantly linked to either fractures or falls, contradicting previous debate.
Spatial arthroscopy integrates surgical video feeds with advanced hardware and software systems, enabling a heads-up display that keeps surgeons focused on the field. This technology improves ergonomics and opens doors to future capabilities like voice commands and automated documentation.
The Mount Sinai Health System has opened the Carolyn Rowan Center for Women’s Health and Wellness, which brings together multidisciplinary clinical expertise, structured care pathways, and leading-edge research to deliver personalized, comprehensive care for women. The Center offers guided multi-visit experiences and coordinated care o...
Researchers developed a senolytic therapy using dasatinib and quercetin, which preserved disc structure and reduced inflammation, highlighting JUN signaling as a key pathway. This preclinical study provides evidence for a potential therapeutic strategy to slow disease progression in individuals with genetic susceptibility.
The Capture the Fracture program has achieved a major milestone, identifying over one million patients with fragility fractures every year. This growth reflects increasing recognition of coordinated post-fracture care services as an essential component of modern hospital care.
Mount Sinai physicians will offer expert guidance and resources to keep pickleball players safe and healthy at more locations than ever before. The partnership aims to promote physical and mental well-being, as well as boost longevity through pickleball.
A new editorial by IOF members highlights the alarming high post-fracture mortality in Africa and emphasizes the need for a targeted, Africa-driven strategy. The authors propose five strategic priorities to build bone health into national health systems, education, and policy.
A pioneering study by the University of Eastern Finland confirms that total hip arthroplasty leads to better outcomes than conservative treatment for patients with moderate-to-severe hip osteoarthritis. The surgery significantly improved pain, functional capacity, and quality of life compared to conservative treatment alone.
A 10-year follow-up study found that partial meniscectomy did not improve patients' symptoms or function, but rather worsened osteoarthritis progression. The study's findings suggest a potential medical reversal, where widely used therapies prove ineffective or even harmful.
The new robotic system combines artificial intelligence, data-driven alignment planning, patient-specific implants, navigation, and robotic screw delivery to enhance precision and coordination. This technology streamlines operating room workflows, reducing procedure time and supporting recovery for patients undergoing spine fusions.
Twenty-three young investigators from 16 countries received the ESCEO-IOF Young Investigator Awards for their outstanding abstracts submitted to the WCO-IOF-ESCEO 2026 Congress. The awards aim to support and attract young researchers to the field of musculoskeletal research.
The International Osteoporosis Foundation has awarded Professor Roland Chapurlat the prestigious IOF Olof Johnell Science Award for his seminal contributions to understanding and managing osteoporosis, osteoarthritis, and skeletal rare bone diseases. He is recognized as one of the leading clinical academics in the field worldwide.
A new international survey reveals that adults with hypophosphataemic osteomalacia face a substantial disease burden, often under-recognised. The study calls for improved awareness, education, and coordinated care to ensure timely diagnosis and optimal treatment.
Professor Radmila Matijevic received the IOF CNS Medal for her outstanding work in advancing bone health awareness, diagnosis, and management. Her contributions to osteoporosis research and clinical practice have improved patient care in Serbia and the wider Balkan region.
Professor Thierry Chevalley has received the prestigious IOF President's Award for his significant contributions to advancing bone health and osteoporosis prevention. With extensive research expertise in geriatrics and bone health, he serves on various scientific committees and leads efforts to develop fracture liaison services.
Professor Noriko Yoshimura has received the IOF CSA Medal of Achievement for her pioneering work on epidemiology and prevention of locomotive organ disorders and osteoporosis. Her research, including the ROAD Study, has significantly advanced understanding of musculoskeletal health.
A new clinical trial at the University of Cincinnati is testing a peptide solution to treat prosthetic joint infections after total knee replacement. The trial aims to reduce the need for repeat surgeries and expand the treatment window beyond two weeks.
A team of researchers has achieved a major milestone in developing a new treatment aimed at helping the body repair damaged joints at the source. The experimental treatments have shown promising results in animal models, restoring joint tissue to near-normal levels and significantly reducing pain markers for long periods.
Researchers identify a three-way link between mechanical stress, integrin signaling, and endocytosis in osteoarthritis. Integrin trafficking may help explain why the same pathways have different effects across disease stages and tissue contexts.
A new platform, Build Better Bones, offers evidence-based guidance and practical resources for osteoporosis management. The platform, developed by the International Osteoporosis Foundation, provides a trusted place for people with osteoporosis to start their journey, with a focus on exercise, nutrition, and home safety.
Researchers discovered that tendon stem cells and progenitor cells fail to differentiate into mature, functional cells, instead promoting scar buildup. Immune cells, including macrophages, also play a central role in sustaining fibrosis, creating a self-sustaining environment that is difficult to reverse.
Researchers have discovered the protective role of LOXL2 protein in preventing cartilage damage and inflammation in temporomandibular joint osteoarthritis. The enzyme helps suppress inflammatory pathways, reducing cell death and preserving cartilage viability even under inflammatory conditions.
Researchers identify three types of post-amputation pain: phantom limb pain, residual limb pain, and musculoskeletal pain, which behave differently and require personalized care. The study's findings suggest that prosthetic design can directly influence comfort during real-world movement, improving mobility and quality of life for indi...
Researchers at NYU Langone Orthopedics present new study on ACL reconstruction in athletes over 50, finding physiological age determines treatment. They also develop an AI chatbot to answer pre- and postoperative questions, improving patient engagement and education.
Researchers at Osaka Metropolitan University found that targeting the glutamine transporter ASCT2 can suppress cell growth and induce apoptosis in synovial sarcoma cells. This study suggests a new approach for treating this aggressive malignant tumor by cutting off its nutrient supply.
A study of 77,947 patients found that those over 80 and with low initial ADL scores benefited from holiday rehabilitation. This suggests prioritizing interventions for elderly and independent individuals can lead to better outcomes.
Researchers identified ApoE as a systemic inhibitor of bone repair during aging, and showed that blocking its activity can restore bone regeneration and improve fracture healing. The study provides hope for therapies that actively restore regenerative capacity in older patients, reducing nonunion risk and improving recovery.
A new clinical study identifies localized reactivation of human cytomegalovirus inside the femoral head as a potential cause of osteonecrosis. The findings suggest that antiviral prevention strategies may be effective in blocking disease progression.
The new program combines limb preservation, amputation care, and reconstructive solutions like osseointegration to improve identity, functional outcome, and quality of life for patients. Patients will receive coordinated, personalized, and expert care that supports their recovery and promotes sustained overall health.
A study highlights the opportunity for orthopedic surgeons to identify patients who have experienced intimate partner violence (IPV), with only 0.3% of referrals compared to 29% from emergency departments. Orthopedic teams can educate and empower patients, providing timely life-saving referrals.
Researchers at Rice University and MD Anderson Cancer Center developed patient-specific models to predict stress and deformation in reconstructed pelvises. The study found that larger bone grafts experience lower stresses and smaller deformations than thinner bones.
The Asia Pacific Regional Audit highlights key trends, gaps, and opportunities in 22 countries and regions. The audit reveals a steep rise in fracture rates due to poor bone health and an ageing population, with China, Malaysia, and Australia experiencing significant increases.
A new study reveals thousands of NHS knee replacement operations are cancelled annually for avoidable reasons, costing millions and prolonging waiting times. Lack of available beds and medical ineligibility were the most common causes, with many cancellations avoidable with advance planning.
Researchers found that patients who can walk at least 1 meter per second before hip replacement have significantly better mid-term postoperative outcomes. This simple and reliable predictor could help physicians determine when to refer patients for surgery, and preoperative rehabilitation programs could be developed.
The 9th IOF Asia-Pacific Bone Health Conference will bring together healthcare professionals, researchers, and policymakers to exchange knowledge and shape the future of bone health across the region. The conference will feature keynote lectures, sponsored sessions, and a launch of the IOF Asia-Pacific Regional Audit 2025.
An international team led by Lehigh University researcher Hannah Dailey is building predictive models to understand and eventually prevent bone healing complications. The team aims to incorporate biological differences into the model, using a library of imaging data from Switzerland's AO Research Institute Davos.
A large-scale study of over 20,000 elective shoulder replacement surgeries in the UK and Denmark found that higher BMI is not linked to increased risk of death or complications. Underweight patients, however, were found to have a slightly higher risk of death.
Researchers have developed a new surgical instrument called the CAP-LIFT cannula that completely transforms arthroscopic procedures in the hip region. The device solves existing problems with limited space and allows for easier maneuverability of tools, reducing complications and recovery time.
Researchers have identified iron-manganese alloys as promising candidates for temporary bone fixation. These alloys combine strength, biocompatibility, and degradation properties, allowing them to support bone healing while degrading naturally. However, challenges remain, including controlling the release of manganese, which can pose t...
A team of researchers at Osaka Metropolitan University has successfully treated spinal compression fractures in rats using stem cells derived from adipose tissue. The study found that these cells can promote bone healing and regeneration, making them a potential solution for osteoporotic vertebral fractures.
A new project led by University of Delaware engineer Michael Hast aims to develop radiation-free imaging techniques that identify problems with bone healing sooner. The team uses 3D computational models and recent advances in magnetic resonance imaging (MRI) to estimate the strength of a healing bone and simulate real-world stresses.
Researchers have developed a novel vaccine strategy using biomaterial scaffold vaccines to protect against Staphylococcus aureus infections in orthopedic device implants. The vaccines, made with immune cell-attaching molecules and S. aureus-specific antigens, create a beneficial immune response that significantly lowers bacterial burden.
A new noninvasive method uses multi-echo ultrashort echo time MRI and shear wave elastography ultrasound to assess the structure and function of the Achilles tendon in professional ballet dancers. The study found that dancers tend to have more tendon stiffness, which corresponds with prior observations of a training effect.
Researchers introduced refinements to a rarely used surgical method, the reverse homodigital dorsoradial flap, for radial thumb defects. The key refinements preserved subcutaneous tissue for venous drainage and left a buffer zone at the arterial pivot point to reduce stress on blood vessels.
A cohort study found that early extracranial surgery was associated with adverse outcomes in function, cognition, and disability after moderate-severe traumatic brain injury. The study suggests that further research is needed to determine if surgical timing or other interventions can improve long-term deficits.
The study found that males have a narrower pelvis, resulting in a more medial starting point for S2AI screws and poorer rod alignment. Researchers aim to tailor treatment to patients' specific anatomy to improve surgical efficiency and outcomes.
Research presented at the European Emergency Medicine Congress finds that doctors and nurses are more accurate than AI in triaging patients in emergency departments. While AI showed some promise in flagging critical cases, its overall accuracy was lower than clinicians' across most metrics.
Researchers have quantified the costs of e-scooter injuries for the first time in Ireland, revealing an average cost of €1,726 per patient. The study found that e-scooter injuries mainly resulted in musculoskeletal injuries requiring major surgery, resulting in significant financial burdens on healthcare services.
Researchers developed an integrated approach to solve the elective surgery assignment, sequencing, and scheduling problem (ESASSP), reducing delays and costs. The study suggests that hospitals can benefit from computationally efficient solutions to minimize operational costs and maximize resource utilization.
Researchers found that nerves with a response to stimulation had a greater likelihood of recovering on their own, while those without a response had a low chance of functional recovery. The study uses intraoperative electrical nerve stimulation as a tool to distinguish between recoverable and non-recoverable nerve injuries.
The International Osteoporosis Foundation identifies critical global barriers to osteoporosis care, including limited DXA scanning and outdated treatment criteria. The IOF advocates for a paradigm shift in bone health management worldwide, recognizing high fracture risk as a valid criterion for treatment and reimbursement.
A new review emphasizes the importance of both physical activity and reduced sedentary time for optimal skeletal health. Emerging evidence reveals that prolonged sitting and inactivity can harm bone health, even among regular exercisers.
Keith Cole has received a five-year grant from the National Institute on Aging to conduct integrated research on dual decline, mobility, cognition and aging. This research aims to identify predictors and treatment targets for older adults at risk of physical and cognitive decline.
The procedure uses a combination of advanced imaging, artificial intelligence, and 3D printing to create a customized implant tailored to each patient's unique anatomy. This technology allows for more precise spinal alignment, reduced surgical complications, and faster recovery times.
A new survey by Ohio State University Wexner Medical Center reveals that many people are unaware of the connection between knee, groin, and hip pain. The study found that 72% of respondents were not aware that knee pain could be a sign of a hip problem.