Articles tagged with Skin
Researchers found a 1000-fold increase in skin microbiota and larger lesions after smallpox vaccination, but all groups had equal protection from re-infection. The study suggests that manipulating commensal skin microbiota might enhance the efficacy of intradermal vaccines.
Researchers at the University of Bristol created a 3D-printed artificial fingertip that produces nerve signals similar to those from human tactile nerves. The innovation could improve robot dexterity and prosthetic hand performance by giving them an in-built sense of touch.
A new study led by Yale University shows that one in three patients with a severe skin disease called alopecia areata were able to regrow hair after being treated with a common arthritis drug. The Phase 3 clinical trials used baricitinib, a Janus kinase inhibitor, to treat the condition.
Researchers from the University of Nottingham have created a detailed molecular map of the skin's stratum corneum using 3D mass spectrometry imaging. This discovery provides fundamental understanding in skin biology and enables the development of new skin products and treatments.
Researchers developed a microneedle treatment that increased desensitization rates to peanut allergy in mice, outperforming existing immunotherapy methods. The novel approach achieved significant results using lower doses of allergen, offering new hope for millions suffering from peanut allergy.
A UC Davis Health study found that taking bile acids or treatments regulating their production levels can help control psoriasis inflammation. Bile acids inhibited skin inflammation by stopping immune T cells from producing proinflammatory protein IL-17A and blocking immune cell movement to the site.
Researchers have developed a cream that prevents frostbite injuries in mice when applied to the skin before severe cold exposure. The cream, called SynAFP, reduces frostbite wound size and speeds healing compared to no treatment. Further studies are needed to determine its effects on humans.
A new algorithm, FusionM4Net, has been developed to classify skin lesions with improved diagnostic accuracy. The algorithm uses a multi-stage data fusion process and outperforms previous state-of-the-art algorithms.
A pioneering test called AMBLor has been developed to predict the spread or return of skin cancer. By analyzing primary tumor biopsies, the test identifies patients at low risk of disease progression, providing them with more accurate information and personalized prognosis.
Researchers identify eleven rare genetic variants associated with eczema, accounting for over 20% of the disease's heritability. The variants are found in genes that code for proteins involved in inflammatory reactions, providing promising targets for new therapeutic approaches.
Researchers developed a new fabrication method for wearable pressure sensors that enhance durability, sensitivity and transparency. The sensors can detect various body movements and health indicators, such as pulse, sweat, and temperature.
Researchers discovered that wound macrophages undergo different metabolic programs to coordinate tissue repair, including the use of reactive oxygen radicals for blood vessel growth. Macrophages also utilize a different type of mitochondrial exchange for anti-inflammatory and reparative functions in late-stage wound healing.
Researchers at A*STAR's Institute of Molecular and Cell Biology have discovered a novel protein therapy using Agrin to promote wound healing and repair. The study found that timely induction or exogenous supplementation of Agrin accelerates the healing process, preserving the mechanical architecture of injured skin layers.
A new virtual histology technology may reduce the need for invasive skin biopsies, providing a biopsy-free solution for rapid diagnosis of malignant skin tumors. The technology uses deep-learning frameworks to transform images of intact skin into detailed, virtually stained images.
Researchers have identified specific skin microbiome bacteria and their pathways as contributing to ageing skin. The study, published in PLOS ONE, used a novel approach to chart host-microbe co-metabolism in skin aging.
Researchers found that nearly 75% of pregnant women with stretch marks reported moderate to prominent embarrassment, which impacted their social activities, self-esteem, and clothing choices. The study highlights the need for open discussions about stretch marks to normalize them and identify potential mental health issues.
Researchers identified two distinct clusters of patients with Prurigo nodularis: those with increased inflammation and those with a higher likelihood of spinal disease. This study suggests that personalized treatment approaches can be tailored to specific patient profiles.
Scientists from Japan discover IL-36Ra plays a pivotal role in wound healing, and Cl-amidine normalizes exacerbated I/R injury. The study's findings suggest IL-36Ra as a potential therapeutic target for cutaneous I/R injuries.
A new study revealed that global guidance for preventing Surgical Site Infections (SSI) is not effective and needs revision. The FALCON trial found no superiority of interventions like alcoholic chlorhexidine skin preparation and triclosan coated sutures over lower-cost alternatives.
Scientists have shown that applying an electric field to the skin affects collagen pathways, temporarily reducing production and increasing degradation. This opens new therapeutic perspectives for the topical treatment of skin fibrosis characterized by excessive collagen deposition.
Researchers identified a bacterium on healthy cats that produces antibiotics against severe skin infections in humans and pets. The discovery may lead to new treatments for MRSP infections in dogs and potentially other inflammatory skin diseases.
A new trial has found that vaginal laser therapy treatments claim to reduce negative vaginal symptoms of menopause – experienced by about half of all women – by up to 100 per cent. However, the study shows they might not work at all, with no difference found between the laser treatment and a placebo.
Researchers found glycerin, a natural ingredient in many skin lotions, reduces psoriasis symptoms by calming scaly patches and promoting healthy skin cell maturation. The study's results support anecdotal reports from patients with psoriasis, providing objective evidence of glycerin's effectiveness in combatting the condition.
A UCI-led study identifies a new molecular pathway that promotes wound healing in the skin by relaxing cell-cell adhesions between migrating keratinocytes. This finding may improve understanding of wound healing biology and lead to new therapies for non-healing wounds like diabetic ulcers.
A team of scientists at McGill University has invented a smart device for personalized skin care inspired by the male diving beetle. The device collects and monitors body fluids while sticking to the skin's surface, paving the way for more accurate diagnostics and treatment for skin diseases like acne.
A Michigan Medicine study found that altering interferon kappa levels in mice with psoriasis-like lesions reduced disease severity. The research suggests using therapies to modulate interferon states may limit inflammation in psoriasis patients.
Researchers at Johns Hopkins Medicine have discovered an enzyme inhibitor, Q-VD-OPH, that boosts the immune system to fight antibiotic-resistant MRSA and other skin infections. The treatment works by reducing apoptosis of neutrophils and monocytes, leaving them in plentiful numbers to remove bacteria.
A study by Massachusetts General Hospital found that COVID-19 vaccine skin reactions are rare, affecting approximately 1.9% of recipients after the first dose. The majority of these reactions did not recur after a second dose, providing critical reassurance to individuals with concerns about vaccination.
A study published in the Journal of Investigative Dermatology found that a Western diet rich in sugar and fat disrupts gut microorganisms, leading to psoriasis flares. Switching to a balanced diet restores gut health and suppresses skin inflammation, offering a potential solution for managing the condition.
A research team from City University of Hong Kong has designed a simple electromechanical device that can detect skin disorders such as psoriasis by measuring tissue stiffness. The device provides real-time evaluations of deep tissue stiffness, allowing for accurate targeting of lesions and monitoring of skin health status.
The researchers developed a biomaterial made from discarded bullfrog skin and fish scales that acts as a scaffold for bone-forming cells to multiply, leading to the formation of new bone. The biomaterial has shown low risk of triggering an inflammatory response and could be used to assist with bone growth around surgical implants.
Studies show distinct neuron populations control itching in hairy and hairless skin, offering hope for targeted therapies. Researchers aim to develop treatments that block itch-inducing neurons, improving quality of life for patients with chronic skin itch conditions.
Scientists at UC San Diego School of Medicine discovered two enzymes, histone deacetylases (HDACs), that inhibit the body's inflammatory response in the skin. These enzymes allow the skin to tolerate certain microbes living on its surface while preventing a constant rash from developing elsewhere.
A ceremonial tsantsa was authenticated and repatriated to Ecuador in 2019, with researchers confirming its origins using CT scans and assessing 33 criteria. The artefact's unique features, such as a distinctive hairstyle and three holes in the lips, matched those of SAAWC culture group members.
A study of 582 participants found that over two-thirds have developed hand dermatitis due to increased hand washing and use of alcohol-based rubs during COVID-19. The study suggests that skin barrier function can help identify suitable modifications to prevent hand eczema.
A modified 5:2 diet has shown promising results in reducing scaling and thickness of skin symptoms in psoriasis patients. The study found a significant reduction in Psoriasis severity after following the MIF diet, with 30% of patients reporting a decrease in itching.
Researchers discovered that strawberry geranium (Saxifraga stolonifera) suppresses excessive immune response mediated by Toll-like receptor 2, reducing skin inflammation. This finding offers a potential alternative to conventional antibiotics and steroid-like compounds used to control dermatitis.
A new study found that short-term exposure to hazardous air quality from wildfire smoke can harm skin health, particularly for those with eczema. The research, conducted during the Camp Fire in 2018, saw a significant increase in patients visiting clinics with concerns of eczema and general itch.
A new care bundle has been shown to reduce the incidence of facial pressure injuries in frontline COVID-19 healthcare workers. The study found that approximately 29% of respondents developed a facial pressure injury prior to using the care bundle, compared to just 8% after its implementation.
Dr. Kelly Haas is studying the structure, stability, and resilience of the hand microbiome in collaboration with GOJO Industries. Her goal is to understand how the hand microbiome responds to hand hygiene events and develop new products that minimize the trade-off between public health and personal hand health.
Delayed injection-site reactions can occur in some patients who received the Moderna mRNA-1273 vaccine, researchers say. Most symptoms clear up after a week, and completion of the second dose should not be discouraged.
A new study has identified a universal strain of bacteria derived from healthy human skin that can treat the most common type of eczema. In a Phase I clinical trial, two-thirds of participants showed significant improvements in symptoms, including reduced itchiness and inflammation.
A new CAD system uses convolutional deep neural networks to identify skin cancer earlier, analyzing multiple lesions and comparing them to a 'ugly duckling' metric. The technology improved upon previous systems with 90.3% sensitivity and 89.9% specificity.
A neural network system analyzes photographs to rank and distinguish suspicious skin lesions, suggesting it can aid clinicians in spotting precancerous marks during clinical visits. The platform's performance was demonstrated with a sensitivity and specificity of 90.3% and 89.9%, respectively, in identifying 'ugly duckling' lesions.
A recent human study found that consuming grapes protected against ultraviolet (UV) skin damage by increasing resistance to sunburn and reducing markers of UV damage. The study attributed these beneficial effects to the natural components polyphenols in grapes, which may act as an edible sunscreen offering additional protection.
The NTU Singapore team has developed a portable device that can create high-resolution 3D images of human skin within 10 minutes. This technology uses electrochemistry and can be used to assess the severity of skin conditions, such as eczema and psoriasis.
A new topical treatment, benvitimod cream, has been proven safe and effective for mild-to-moderate plaque psoriasis. In a phase III clinical trial, the cream achieved a 75% decrease in psoriasis size and severity compared to pre-treatment levels.
A new study reveals that people with a genetically weakened skin barrier are more susceptible to faster uptake of common chemicals, increasing the risk of skin diseases and cancer. Researchers screened 500 participants in Sweden, finding twice as high doses of pesticides in those with the mutation.
Increased diagnostic scrutiny is linked to rapid rise in melanoma diagnoses, according to a study published in The New England Journal of Medicine. Melanoma incidence has doubled among adults 65 and older over the past two decades, despite stable mortality rates.
Researchers investigate the body's own pain control system using Conditioned Pain Modulation (CPM) and find that two different stimuli can reduce pain to a similar degree. The study used electrical stimulation of the skin as a new test stimulus, allowing for objective measurement of brain activity.
A study published in Scientific Reports reveals that mutations in a gene underlying a rare skin disorder can also lead to arrhythmogenic right ventricular cardiomyopathy, a serious heart disease. The findings indicate that the genetic underpinnings of skin disorders at birth may help predict future heart problems.
A recent study published by North Carolina State University researchers has identified a significant association between Bartonella infection and the development of neuropsychiatric symptoms, including depression, anxiety, and sleep disorders. The study also found that many patients with Bartonella infections exhibited skin lesions, wh...
Researchers found individuals with atopic dermatitis are more likely to have autoimmune skin and gastrointestinal diseases. The study, published in the British Journal of Dermatology, analyzed over 104,000 cases of atopic dermatitis and identified its association with various autoimmune conditions.
Researchers developed a microneedle-based technique to extract dermal interstitial fluid, which could provide valuable information for routine clinical monitoring and diagnostic testing. The study found that ISF contains unique compounds not found in blood samples, offering potential insights into skin exposure to products and pesticides.
A new microneedle skin patch has been developed by UConn researchers to provide immunization against infectious diseases through a single administration. The patch triggers a high immune response and offers a long-term protection similar to multiple injections.
A pilot study found that consuming Ataulfo mangoes four times a week reduced deep wrinkles by 23% in postmenopausal women after two months. However, eating more than half a cup per serving may increase wrinkles due to high sugar content.
Researchers at the University of Córdoba have developed new molecules derived from cannabidiol, which induce the expression of heme oxygenase 1 and activate NRF2 to exhibit dual antioxidant activity. This mechanism has great potential for treating skin diseases like atopic dermatitis and epidermolysis bullosa.
Researchers found that dietary intervention increased skin gene expression manifold, with raw food activating the immune defense system and increasing antioxidant production. This study suggests that a raw diet may help activate the immune defense of dogs, potentially reducing the risk of atopic dermatitis.
A challenging case study found that wearing a face mask with elastic bands worsened a man's existing skin allergies. Common allergens in masks and their components can trigger symptoms in people with pre-existing skin conditions.
Black and Hispanic children in the US experience more severe eczema than their white counterparts. Additionally, they are less likely to report overall excellent health. The disparities exist due to differences in how the condition appears on diverse skin tones, requiring individualized treatment approaches.