A new study reveals that higher body temperature can alter key proteins in individuals with mevalonate kinase deficiency, a devastating genetic disorder. The research provides insights into the underlying physiology of the condition and suggests potential new treatment approaches.
Researchers at Scripps Research have discovered that chronic circadian disruption can increase lung cancer growth in animal models by activating the heat shock factor 1 (HSF1) pathway. This finding suggests a molecular link between disrupted sleep patterns, temperature changes, and tumor formation.
A scientific review found that cold water swimming can reduce 'bad' body fat and improve insulin sensitivity. However, the health benefits are uncertain due to limited study quality and variability in participant profiles.
Repeated cold-induced shivering improves glucose tolerance, decreases fasting blood sugar, and reduces blood fat levels in overweight adults. It also markedly lowers blood pressure and has a beneficial effect on triglycerides and free-fatty acids.
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Researchers from the European Insomnia Network found that outdoor nighttime temperatures outside thermal comfort can affect human sleep. To combat this, try keeping a bedroom below 25 degrees Celsius, using fans instead of air conditioning, and staying hydrated during heatwaves.
A new study predicts that record-breaking heat waves will become more frequent in places like North America and Europe by 2100. The research suggests that even if countries meet the Paris Agreement goal of limiting warming to 2°C, dangerous heat stress could double by 2100 in the tropics.
Researchers used x-ray crystallography to study the main protease of SARS-CoV-2 at various temperatures, revealing subtle conformational changes and potential targets for drug design. These findings may inspire the development of new antiviral drugs to counteract COVID-19 and prevent future pandemics.
Researchers found that night-shift workers experience disrupted sleep quality and circadian rhythms, even after years of night shift work. Their study, published in eBioMedicine, used wearable tech to monitor 140 workers, revealing a significant impact on health.
The MedSENS instrument measures body temperature, heart rate, and oxygen saturation from the ear canal using innovative sensors. It has been tested in harsh environments and proven to be easy to use, with its data transmitted wirelessly to other devices.
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Scientists at CNIC discovered a complex network between liver tissue connections that allows the liver to regulate body temperature. The secretion of IL-12 by liver-infiltrating macrophages blocks FGF21 production, reducing heat generation by brown fat in mice.
Research reveals that healthy brain temperature varies significantly by brain region, age, sex, and time of day. Daily brain temperature cycles strongly correlate with survival in traumatic brain injury patients, suggesting potential improvements in understanding and treatment of brain injuries.
Researchers found that birds infected with lipopolysaccharide from bacteria reduced their body temperature by 2°C to conserve energy. In contrast, chicks fed and warm did develop fever. The study suggests that regulated hypothermia is an energy-saving response during severe infection, prioritized over maintaining a fever.
Researchers at UNIGE discovered that temperature changes trigger organ-specific effects in all tissues, leading to distinct gene expression profiles. The study's web-based application provides access to thousands of gene expression profiles, enabling further research and potential therapeutic applications.
Research finds that bat box design and landscape placement significantly impact the energetic balance of endangered Indiana bats. A study by University of Illinois researchers tested five bat box designs and four landscape placements to determine their effects on bat metabolism, development, and survival.
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Researchers at Institut Pasteur have found that hypothalamic neurons can directly detect variations in bacterial activity, adapting appetite and body temperature accordingly. This discovery could lead to new treatments for diabetes and obesity.
Researchers found that using indoor fans can increase the indoor temperature threshold before discomfort sets in by 3-4°C, reducing the need for air conditioners. The study also revealed a significant reduction in energy consumption and associated greenhouse gas emissions by up to 70%.
A study finds that extreme heat is associated with a significant increase in cardiovascular mortality, particularly among men and non-Hispanic Black adults. The researchers analyzed data from over 3,100 counties in the US and found that each additional day of extreme heat was linked to an average of 600-700 additional deaths per year.
A study published in Nature Metabolism found that body temperature has a greater impact on lifespan than metabolic rate, contrary to the traditional 'live fast, die young' phrase. The researchers used an unusual experiment where high temperatures increased lifespan by lowering metabolism and reducing body temperature.
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A study by researchers from the University of Tsukuba found that taking a 15-minute walk outside on a hot summer day can impair cognitive performance. This effect was more pronounced in men who slept less than 5 hours, suggesting that heat stress may negatively impact learning and productivity.
A team of scientists developed an AI-based model to predict personal thermal comfort based on spatial parameters, achieving exceptional accuracy. The study highlights the importance of incorporating architectural features in models to reduce energy consumption.
A new study found that aging and disease alter body temperature rhythms in mice, mirroring the disruption seen in humans. In young, healthy mice, daytime temperatures were lower than nighttime temperatures, but this difference disappeared in older, diseased animals.
Researchers have developed a custom finger clip device that measures blood pressure and other vital signs like heart rate, oxygen saturation, body temperature, and respiratory rate. The device uses photoplethysmography sensors and achieves an accuracy rate of about 90% for systolic blood pressure.
Researchers at the University of Illinois developed a new bat box design that provides more thermally appropriate roosting spaces for bats. The 'rocket box' style, with modifications to length and insulation, helps reduce the risk of overheating and provides space for bats to move and avoid extreme temperatures.
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Scientists have developed a new method using CRISPR-Cas9 to target specific fat cells, reducing the time and cost of genetic discovery in obesity research. The technique allows researchers to study genes in brown adipose tissue, which plays a crucial role in regulating body temperature.
A team of researchers proposes that endothermy in mammals and birds has a common ancestry and is much older than previously accepted. They found evidence of endothermy in early ancestors of modern birds and mammals, including Pelycosaurs and Pareiasaurs.
A lung model mimicking complex anatomy has enabled the assessment of respiratory volumes using a gas-in-scattering-media absorption spectroscopy (GASMAS) technique. The study demonstrates the feasibility of GASMAS to sense changes in gas volume in a controlled environment, paving the way for potential clinical applications.
A Harvard University study estimates Americans perform about 30 minutes less moderate-to-vigorous physical activity daily compared to 200 years ago. The decline is attributed to technology, with researchers using historical body temperature records as a 'thermometer' of population-level physical activity.
A study by TUM demonstrated the effectiveness of an ear sensor in monitoring COVID-19 risk patients remotely, providing timely hospitalization when necessary. The sensor enabled high-quality monitoring comparable to hospital care, with great patient satisfaction and improved safety outcomes.
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A new study asked over 470 firefighters about their recovery methods in extreme heat, finding that simple strategies like finding shade and drinking water are often used. The research suggests potential for better cooling and recovery protocols to improve firefighter safety and performance.
The Lancet reports that extreme heat is becoming a major health issue, with over 356,000 deaths in 2019 related to heat. Effective cooling strategies are needed to protect vulnerable populations and mitigate climate change.
A new study finds that urbanization is causing many mammal species to grow bigger, contrary to Bergmann's Rule. The study analyzed over 140,000 measurements of body length and mass from North American mammals collected over 80 years.
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The University of Maryland associate professor will use genetics, cell biology, and pharmacology to examine the mechanisms of copper transport and its connection to thermogenesis and fat burning. The research aims to improve human health by understanding how copper relates to hypothermia, obesity, and diabetes.
Researchers at Saint Petersburg Electrotechnical University LETI developed a high-precision instrumental method to measure rapid temperature fluctuations of human skin. This allows for non-invasive monitoring of blood flow and assessment of microcirculation disorders.
A retrospective study of over 3,900 patients found that warming iohexol 350 contrast media did not significantly reduce adverse reactions or extravasations. The results suggest that maintaining the agent at room temperature is non-inferior to warming it to body temperature before injection.
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Research suggests that climate, particularly temperature, drove changes in human body size, while brain size evolved independently. Larger-bodied people tend to live in colder climates today.
Male dragonflies have evolved larger melanin wing patches in cooler climates to cope with warmer temperatures. Climate change may lead to even smaller patches in the future, according to research published in PNAS.
Researchers found that the side of a chocolate bar facing the mold has a more orderly crystalline structure than the air-side face. This difference in crystal form could lead to improved taste and texture, as well as better appearance.
Scientists have developed a small, flexible thermoelectric generator that converts heat from human skin into electrical power. The device can power an LED light in real-time when worn on a wristband, suggesting potential for powering wearable devices like fitness trackers.
Scientists found a strong correlation between insect body size and temperature in fossil midges, revealing a promising new proxy for palaeotemperatures. The study suggests that insects can be used to reconstruct ancient climates dating back to the Cretaceous period.
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A new study finds that traditional surface temperature scanners are ineffective in detecting fever-related illnesses, like Covid-19. Instead, taking temperature readings from a person's fingertip and eye may provide more accurate results.
A new study suggests that temperature scanners are unreliable for detecting Covid-19 due to false negatives and varying factors affecting skin temperature readings. Taking temperature readings from a person's fingertip and eye can provide a more reliable indicator of fever-induced changes in deep body temperature.
Researchers found that rising lizard temperatures and predation by snakes are changing the thermal biology of lizards, making them more active at warmer body temperatures. The study suggests that lizard body temperatures and running speeds have increased accordingly, helping them escape snakes.
Achieving target body temperature quickly is vital for patients with witnessed out-of-hospital cardiac arrest, leading to more favorable neurological outcomes. Extracorporeal cardiopulmonary resuscitation (ECPR) shows promise as a treatment option when combined with ECMO.
A new study published in Obstetrics and Gynecology analyzed data from over 310,000 Japanese women to investigate age-related and seasonal variations in menstrual cycles and body temperatures. The researchers found that the average menstrual cycle length increased until age 23, decreased until age 45, and then increased again.
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Researchers have found a significant decline in average body temperature among healthy adults worldwide, with a drop of 0.09°F per year over the past two decades. The study, conducted in Bolivia and the US, suggests that improved hygiene, clean water, vaccinations, and medical treatment may be contributing factors.
Researchers used roundworms to uncover a DNA damage mechanism in sperm, which can lead to male infertility caused by high temperatures. The study provides insight into how temperature affects sperm development and suggests a potential molecular basis for heat stress-induced fertility issues.
Researchers at SUTD developed a method to preheat gelatin ink, increasing its printing time and producing high-quality prints. The study found that preheated gelatin exhibited greater change in volume, allowing for size changes post-printing.
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A new study reveals that reducing calorie intake triggers significant health benefits by lowering body temperature. The research, led by Scripps Research Professors Bruno Conti and Gary Siuzdak, provides a comprehensive understanding of the role of temperature in metabolism during calorie restriction.
A new study found that cold temperatures are responsible for 94% of temperature-related deaths, even though hypothermia affects only 27% of hospital visits. This highlights the need for improved awareness and education around cold injury risks, particularly among vulnerable populations.
Higher temperatures can improve cleansing, but beyond a point, decrease efficiency; optimal cleansing found at 45C with fixed power consumption
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Apple Watch Series 11 (GPS, 46mm) tracks health metrics and safety alerts during long observing sessions, fieldwork, and remote expeditions.
Researchers from The University of Manchester created a prototype garment that can lower the body temperature in hot climates using graphene's remarkable thermal properties. The technology also opens up new possibilities for interactive infrared displays and covert communication on textile.
A study found that female great tits can reduce their body temperature at night when fed supplemental food during winter, increasing survival chances. In contrast, male great tits do not exhibit a similar response, suggesting males prioritize access to food.
Researchers at the University of Tsukuba and RIKEN in Japan have identified specific cells in the mouse brain that can trigger a hibernation-like state when activated. This discovery has significant implications for potential human hibernation applications, including medical uses such as emergency transport or critical care situations.
Researchers have identified a small mitochondrial uncoupler called BAM15 that decreases body fat mass in mice without affecting food intake or muscle mass. The molecule also shows promise in reducing insulin resistance and oxidative stress associated with obesity and related diseases.
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Researchers have identified specific proteins in bones that can help estimate the post-mortem submerged interval, which is challenging due to various environmental factors. The study found that certain proteins decrease or modify over time, providing potential biomarkers for estimating the length of time a body has been underwater.
Common shrews have a high metabolic rate and quickly deplete their fat reserves in winter. However, they do not need to increase their metabolism in response to colder temperatures, thanks to their unique adaptation of shrinking in autumn and growing in spring.
Scientists at Tohoku University have created a white powder that luminesces when heated, allowing for the potential monitoring of internal body temperature. The powder, made of zirconia, can be injected into the body and then illuminated with a near-infrared laser to induce luminescence.
A Scripps Research study found that blocking the kappa opioid receptor while on a restricted-calorie diet resulted in significant weight reductions. Blocking this receptor may be a potential treatment approach for obesity.
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Researchers at the University of Malaga created a low-cost T-shirt that generates electricity from temperature differences between the human body and surroundings. The 'e-textile' prototype uses biodegradable materials such as tomato skin and carbon nanoparticles to produce electrical power.
Researchers have developed a computer vision system that can distinguish between survivors and deceased bodies from 4-8 meters away. Using cardiopulmonary motion, the technology detects tiny chest cavity movements indicating heartbeat and breathing rate, providing a more accurate means of detecting signs of life in disaster zones.