Researchers at UT MD Anderson Cancer Center have made significant advances in understanding cancer biology, developing AI-powered atlas of tertiary lymphoid structures as prognostic biomarkers, and uncovering drivers of resistance to KRAS inhibitors. Additionally, they have discovered a molecular pathway that drives stressed cells to b...
Fraud is a widespread and complex phenomenon that affects millions worldwide. The authors of a recent study emphasize the need for coordinated efforts to mitigate its impact. They argue that psychologists can play a vital role in understanding scams and developing effective countermeasures, particularly in the age of AI.
A new study by Karolinska Institutet shows that daily smartphone-based heart rhythm monitoring can reduce same-day cardioversion cancellations by 94.7% and save significant healthcare resources. The method, called CORAI, uses photoplethysmography to measure small changes in blood flow, allowing for accurate heart rhythm assessment.
A new study by plant biologists at the University of California, Santa Cruz, found that hummingbirds deliver more pollen per visit than bees. This challenges a longstanding idea that stems from the large number of flowers in the mountains of Central and South America that have evolved to be pollinated by hummingbirds instead of bees.
A new study suggests that adding low-dose glucocorticoids to maintenance treatment for ANCA-associated vasculitis (AAV) does not reduce the risk of major flares, but is associated with an increased risk of chronic damage and hospitalization. In contrast, rituximab use was linked to a lower risk of major flares.
A new study found that vitamin D insufficiency is widespread among older adults and minoritized ethnic participants in northern Britain. The research challenged the belief that summer sunlight can restore healthy levels of vitamin D.
Researchers found that obexelimab significantly reduces the risk of relapse in patients with IgG4-related disease, a rare chronic immune condition. The study showed that patients treated with obexelimab were nearly twice as likely to be in complete remission after one year and needed less emergency steroid treatment.
Senescent cells that stop dividing but don't die can become abnormally active, causing inflammation and instability in blood vessel plaques. The study found that losing key regulatory proteins activates the CD38 enzyme, leading to a higher risk of blood clots and cardiovascular events.
Researchers have developed operational definitions of srSLE based on disease activity and treatment exposure, showing strong predictive performance. A novel autoantibody signature has also been identified to predict atherosclerosis progression in juvenile-onset systemic lupus erythematosus
The AGA GI Opportunity Fund invests in Amplified Sciences to advance PanCystPro, a next-generation diagnostic assay for improving pancreatic cyst risk assessment. The funding supports completion of a pivotal real-world observational study and expansion of commercial partnerships.
Researchers developed CardioNVT, an AI platform for high-throughput cardiomyocyte ploidy assessment. The platform accurately recognizes and segments cardiomyocyte nuclei from DAPI-stained images, enabling the analysis of nuclear volume distribution and inferred ploidy.
A cross-sectional study found early age–onset colorectal cancer patients with improved overall survival but delayed treatment experienced worse outcomes. Language barriers may be a modifiable risk factor contributing to these delays.
Sebaceous adenoma is a rare, slow-growing benign tumor arising from sebaceous glands. A new case report describes the clinical, histopathological, and immunohistochemical features of this tumor, highlighting its diagnostic challenges and importance of distinguishing it from more aggressive conditions.
Researchers have developed soft, brain-inspired electronics that can sense, store, and process information while conforming to biological tissues. These devices mimic the chemical processing of the human brain, executing complex tasks like heart rhythm classification at ultra-low voltages.
The study evaluated digital platforms and AI chatbots for improving health literacy in patients with RMDs. The results showed high usability, perceived usefulness, and trust among participants, suggesting a promising approach to patient education.
Scientists discovered a new way cells fight infection, using a method called antibody-directed xenophagy (ADX), which can digest bacteria and viruses inside infected cells. ADX is triggered by a protein called TRIM21, which flags invading pathogens for destruction.
A new study using the EUSTAR database found that patients with active disease at baseline had higher cumulative incidence rates of organ and multi-system involvement. Early disease activity monitoring is crucial for identifying patients at risk, guiding treatment decisions, and improving patient outcomes.
Researchers at KAIST discovered that a DNA repair enzyme uses a one-dimensional diffusion strategy to search for damaged sites. The team found that an intrinsically disordered region plays a key role in the DNA search process and stabilizes binding between APE1 and DNA with magnesium ions.
A breakthrough single-cell method, D&D-seq, enables researchers to map DNA-protein interactions, overcoming technical limitations of current methods. This technology is expected to revolutionize the study of gene regulation and its role in diseases.
Researchers developed a deep-learning framework that uses real-world measurements to design optical surfaces with precise control over light behavior. The AI model achieves high consistency with experimental results while reducing simulation costs and time.
Comorbidities such as cardiovascular disease, cognitive impairment, and osteoporotic fractures are common in RMD patients. Systemic autoimmune diseases increase the risk of cardiac arrhythmias and mortality. PPI use is linked to a higher risk of major osteoporotic fractures, while JAKi therapy may pose a risk of venous thromboembolism.
Dr. John Findley, a physician executive with extensive experience in lifestyle medicine, has been named the new CEO of the American College of Lifestyle Medicine (ACLM). He will lead the organization in advancing its mission to establish lifestyle medicine as a standard of care for every patient, every time.
A 20-year study in the UK, Australia, and US reveals a significant increase in menopause-related search patterns focused on commercial products and services. This shift indicates a growing need for non-clinical guidance and support beyond traditional clinical encounters.
Transplant survival rates are improving thanks to medical and technical advances, including better organ preservation strategies and expanded donation criteria. However, the number of people needing transplants continues to exceed the available organs, particularly for kidneys.
A new study reveals that specific neural circuits can be activated to reverse structural abnormalities associated with autism spectrum disorder. Researchers successfully restored the axon initial segment's length and improved behavioral abnormalities in an ASD mouse model.
A study by researchers at Science Tokyo found that non-structural disaster measures in Macau significantly improved coastal resilience and reduced storm-surge impacts. The city's emphasis on evacuation guidance, communication, monitoring systems, and public awareness helped build trust and reduce disaster impacts.
Researchers will measure particulate matter, ozone, wind, humidity, and temperature to understand environmental response to large-scale human activity. The study aims to find a balance between development and clean air, supporting sustainable growth in the Dallas-Fort Worth area.
Researchers developed ADASPEC to speed up multilingual AI systems by dynamically adapting to different languages during inference. The framework generates instruction data in any desired language using the target LLM itself, reducing unnecessary vocabulary computations and achieving faster and more stable multilingual inference.
Researchers found that glandular and squamous cancer cells share a common origin but diverge early in tumor development. This discovery challenges the long-standing debate over whether each cancer subtype originates from distinct cells or a single multipotent cell.
Researchers have found a new species of dinosaur, Jian changmaensis, which is believed to be the missing predator that hunted early birds. The dinosaur had long feathers on its front and back limbs, giving it four 'wings' that may have been used for gliding.
By 2050, the North Sea is projected to have around 58,500 square kilometers of offshore wind farms, with the Netherlands occupying 19% of its waters. The UK, Germany, and Denmark are expected to dominate in scale, with the Netherlands being the most intensively used national zone.
Astrophysicists at Northwestern University have discovered evidence of a powerful wind blowing from the Milky Way's central supermassive black hole, Sagittarius A*. The study resolves one of the longest-standing mysteries in astronomy and opens a new window into the physics at play in the center of the Milky Way. The team used five yea...
Alex Zhavoronkov, founder of Insilico Medicine, has been named to the inaugural SCW75 list for his work in AI-driven drug discovery and longevity research. The company's Pharma.AI platform has drastically compressed traditional drug discovery timelines, advancing 30 developmental candidates to clinical trials.
Researchers developed a topical gel formulation with 4-aminopyridine to treat burn wounds, achieving near-complete closure in 21 days. The gel delivers the drug directly to the wound site, avoiding systemic risks associated with prolonged use.
Stevie Nicks has made a major gift to establish the Stevie Nicks and Joseph Sugerman, MD, Endowed Chair in Otolaryngology, honoring Dr. Sugerman's impact on patients and the field of ENT. The chair will be held by Michael M. Johns, MD, director of the USC Voice Center.
A study by Norwegian University of Science and Technology found that eight different skills in football are unrelated and require separate practice. The research involved 23 semi-professional players who underwent technical exercises to measure their skills in areas such as dribbling, passing, and shooting.
A simple, seven-second X-ray scan can accurately detect the severity of pulmonary valve regurgitation in patients with repaired Tetralogy of Fallot. The test uses dynamic chest radiography and requires minimal radiation, offering a more accessible diagnostic option for those who cannot undergo traditional methods.
Research highlights parents' beliefs and active participation in kindergarten as key factors supporting preschoolers' academic skills. Children's cognitive processes and learning skills significantly predict their academic abilities.
SwRI's Intelligent Systems Division has achieved CMMI, ISO 9001, and CMMC certifications to demonstrate its commitment to delivering secure and reliable transportation solutions. The certifications validate SwRI's robust cybersecurity protections and quality management framework.
Researchers found that robots trained on consistent demonstrations achieved higher success rates than those trained on complex data. Consistent approaches emphasized steady progress toward a goal and reused predefined motions to reduce variability.
Researchers created a way to spot and correct distortions in light using artificial intelligence and a tiny optical element. The approach can improve the quality of images in fields like biology, astronomy, and precision manufacturing by making advanced optical systems faster, smaller, and easier to use.
Scientists have developed a method to measure the electronic structures of liquid water and organic molecules using soft X-ray absorption spectroscopy. By controlling the thickness of the liquid layer, they obtained XAS spectra of both the bulk liquid and the solid-liquid interface.
A study published in Nature Medicine reveals that distinct cellular programs and immune-cell states are associated with Alzheimer's disease progression and resilience. Microglial responses were found to be critical in determining whether Alzheimer's pathology leads to dementia, suggesting new avenues for therapies to prevent neurodegen...
The How to Do Research and Get Published webinar series, offered by Sage, has been recognized for its excellence in publishing education and training. The award highlights Sage's commitment to providing accessible and actionable insights to support researchers worldwide.
Researchers identified molecular differences in saliva after a full night's rest and 24 hours without sleep, creating a potential non-invasive test for sleep deprivation. The 'sleepiness fingerprint' holds promise for roadside checks and other situations where accurate detection is needed.
A new study found that irregular sleep patterns, including variability in timing and duration, are associated with lower receptive vocabulary and visuospatial memory scores in preschool-age children. Despite accounting for total sleep time, greater variability in sleep midpoint was linked to lower verbal performance.
Adolescents with irregular sleep and insomnia symptoms have higher odds of overnight hospital stays and poorer general health in their 20s. Poorer sleep health during adolescence is associated with a range of negative outcomes, including lower life satisfaction and reduced overall well-being.
The American Heart Association has named eight companies to its Heart and Brain Health Accelerator, a program designed to advance innovative technologies in cardiovascular health. The selected companies will receive mentorship, coaching, and capacity building from the American Heart Association Ventures.
Adults with lower measured glomerular filtration rates had a higher risk of all-cause mortality, kidney failure, and major adverse cardiovascular events. Lower GFR values were also associated with increased hospitalization for heart failure and acute kidney injury.
Researchers developed a system to link polyphenol chemical structures with bitterness, acidity, and astringency. Polyphenols found in tea, cocoa, and other foods influence taste sensations, affecting food preferences and digestive responses.
Researchers discover that breast cancer cells exploit protective systems in bone marrow to remain dormant, using Notch2 signaling and genes like CXCR4 and TIE2. This dormancy allows cells to reactivate years later, leading to secondary tumors.
In patients with advanced chronic kidney disease at high cardiovascular risk, low-dose rivaroxaban did not reduce the composite risk of a cardiovascular outcome. Major bleeding rates were significantly higher in the low-dose rivaroxaban group compared to the placebo group.
A pioneering pilot clinical trial showed that spinal cord stimulation improved arm strength by 32% in stroke survivors, with significant reductions in muscle spasticity. The intervention required minimal training time and was safe with no serious adverse events.
A digital 'super-brain' with physics-based knowledge significantly speeds up the design and development of optical components, such as those for quantum computers and camera lenses. By integrating physical principles into machine learning algorithms, researchers reduce simulation time from months to days.
Researchers at Lehigh University developed a new gold-palladium catalysis mechanism that increases reaction rates and stabilizes catalysts. This breakthrough advances the development of more efficient bio-based chemical manufacturing processes.
Researchers have described two new Hydropsyche species from the Middle East and Caucasus, highlighting the importance of traditional morphological examination and advanced DNA analysis. The discoveries, made in Azerbaijan, Iran, and Türkiye, underscore the region's vast potential for new aquatic species yet to be found.
A new study reveals that ancient Britons likely transported the Altar Stone of Stonehenge 700km across challenging terrain, requiring careful planning and coordination. The research uses mineral grain dating and ice-sheet modeling to confirm human transport over natural Ice Age processes.
Researchers found that pregnant Pacific pocket mice trained to fear snakes produce more vigilant offspring, which survive better in the wild. This method of antipredator training may improve conservation breeding and reintroduction programs.
Researchers at Georgetown University Medical Center found that the brain can remodel its architecture to automate learned tasks, enabling true multitasking. This challenge previous theories on human multitasking and has implications for artificial intelligence capable of building on prior learning.
A Korean research team developed a new technology to prevent electrolyte layer cracking in solid oxide electrolysis cells. The new design improved Faradaic efficiency and current density, achieving highly efficient conversion of CO2 into carbon monoxide.