The research team led by Michal Hocek successfully pushes the boundaries of DNA structure and function. They demonstrate that heavily modified double helices are stable enough to be used in medicine, mimicking natural molecules with therapeutic potential.
Researchers developed a novel method for extracting DNA from trace evidence samples, outperforming commercial reagent kits. The technique used modified lysis buffer and chitosan coated magnetic beads, achieving a detection limit of 10 cells.
Researchers developed a method to produce highly strong and tough silk by feeding silkworms with rare earth ion-modified diets. The incorporated ions enhance mechanical performance through chemical interactions.
Researchers have discovered that high-quality lignin can be extracted from cocoa pod husks and modified to have flame-retardant properties. The team's modified lignin biopolymer charred when heated but did not burn, suggesting its potential as a fire suppressant.
Researchers find evidence supporting Modified Newtonian Dynamics (MOND) as an alternative to Planet Nine hypothesis. MOND predicts precise orbital clustering in the outer solar system, which could be indicative of a modified law of gravity at play.
A new study reveals that grasses can transfer DNA from other species into their genomes through lateral gene transfer, giving them an advantage in growth and adaptation. This process could inform future work to improve crop productivity and resilience.
Researchers developed a new base modification, Z-mRNA, that demonstrates low immunogenicity and reduced cytotoxicity compared to unmodified mRNAs. The modified mRNA can induce a substantial immune response and has potential therapeutic applications beyond COVID-19 vaccines.
Researchers successfully produce full-length spider silk proteins using genetically modified silkworms, offering a sustainable alternative to synthetic commercial fibers. The production of spider silk fibers is six times tougher than Kevlar used in bulletproof vests.
Researchers have genetically engineered Vibrio natriegens to produce enzymes that can break down polyethylene terephthalate (PET) in salt water. This breakthrough addresses the challenge of removing plastics from oceans and could lead to more sustainable solutions.
Researchers at the University of Alabama at Birmingham have developed a modified messenger RNA that can temporarily induce cardiomyocyte cell division, leading to reduced infarct size and improved heart function. The treatment has shown promise in mouse and pig models without increasing the risk of deadly arrhythmias.
A new review highlights the current state of the art in autism research, using genetically modified mice to analyze the molecular and physiological mechanisms behind autism. The insular cortex is found to be crucial for emotions, empathy, and motivation in both mice and humans.
Researchers found that genetically modified tobacco mutants, impaired in their defenses, outperformed wild-type plants in years with low herbivore pressure. The mutants' prioritization of growth and reproduction over defense allowed them to thrive in environments with limited insect damage.
Researchers at CityU and HKUMed developed genetically modified human neural stem cells that promote neural circuit reconstruction, reduce glial scar accumulation, and enhance axon outgrowth. The therapy demonstrates potential for treating severe spinal cord injuries with functional recovery.
Scientists have developed a new genetic technology called Ifegenia that suppresses populations of Anopheles gambiae mosquitoes, which primarily spread malaria in Africa. The system targets females, which are the primary disease carriers, and kills them, halting parasite transmission.
Researchers analyzed data from the first genetically-modified pig heart transplant into a human patient and found that several overlapping factors contributed to heart failure, including poor pre-transplant health, immunocompromised state, and use of intravenous immunoglobulin. The study provides crucial insight into how these factors ...
A new study reveals a consistent difference in favorability ratings between gene editing and genetically modified organisms (GMOs) in social and traditional media. Gene editing consistently receives higher favorability ratings, with close to 100% achieved in numerous monthly values, indicating a positive shift in public sentiment.
A recent study by researchers at the University of Zurich found that the Notch signaling pathway plays a crucial role in shaping and varying tooth enamel. The team used genetically modified mouse models to analyze the effects of the Notch-ligands on teeth, revealing that their absence affected tooth morphology and enamel formation.
Researchers at Uppsala University developed a modified lactic acid bacteria treatment that accelerated wound healing in humans. The study showed improved outcomes and safety with ILP100-Topical, a potential new treatment for complex and hard-to-heal wounds.
Scientists have developed a new method to genetically modify brain organoids, allowing for quick and effective analysis of gene function in early stages of brain development. This breakthrough enables comparative studies across primate species and simulates neurological diseases without animal experiments.
The study of Balto's genome provides new insights into the genetics of working dogs, revealing they were more genetically diverse and healthier than modern breeds. The analysis also identified beneficial adaptations in genes related to physical traits such as weight and skin thickness.
Researchers from Lund University have designed a cocktail of modified antibodies that tag the virus to be eliminated by the immune system. The study found that combining different combinations of these antibodies can improve their function, suggesting a potent clinical effect against SARS-CoV-2 and its variants.
A genetically engineered probiotic has been shown to blunt the ill effects of alcohol in mice by reducing alcohol absorption and prolonging tolerance. The treatment also shortened recovery time after alcohol exposure and reduced liver damage. Further research is needed to confirm its effectiveness in humans.
A recent study found that a modified Mediterranean ketogenic diet can decrease the risk of Alzheimer's disease by modifying biological pathways linked to the disease. The diet showed robust changes in gut microbiome and reduced levels of gamma-aminobutyric acid, a neurotransmitter associated with Alzheimer's.
The funding will support preclinical research using genetically modified pigs, aiming to improve compatibility and reduce immune rejection in xenotransplantation. The goal is to enable human clinical trials and address the organ shortage crisis.
Scientists from CSIC and UPV create modified ABA receptor activated by iSB09 molecule, increasing drought tolerance in plants. The combination efficiently activates the ABA pathway, triggering adaptive mechanisms and reducing water loss.
A new study presents the field's top 100 most pressing questions for research to address challenges facing humanity. These questions cover topics such as genetically modified organisms, plant-based fuels, and growing plants in space to support human life.
Scientists create modified E. coli bacteria that cannot be infected by viruses while minimizing gene escape into the wild. This breakthrough technology has implications for reducing viral contamination in biotechnology production, such as insulin production and biofuel manufacturing.
The Janelia FlyLight Project Team has released over 74,000 images of fruit fly brain neurons, generated from more than 5,000 different genetically modified fly strains. These images are now freely available for scientists to quickly and easily find the neurons they need to test theories about the nervous system.
Scientists have genetically modified potatoes and tomatoes to produce betacyanin, a pigment with anti-inflammatory properties. The transgenic vegetables demonstrated enhanced accumulation of the pigment, which showed improved effects in reducing inflammation in macrophage-like cells and murine models of colitis.
A study by University of Gothenburg researchers identifies two distinct types of cod, 'offshore cod' and 'coastal cod', genetically adapted to different environments. The coastal cod remain in the fjords, but their adult stage is uncertain, with possible spawning locations still unknown.
Researchers have designed a treatment that uses a modified bacterium to target and dissolve biofilms caused by Pseudomonas aeruginosa, a leading cause of hospital mortality. The treatment has shown significant efficacy in mice, reducing lung infections and doubling survival rates.
Using genetically modified Aspergillus fungi, researchers have successfully converted polyethylene plastics into pharmacologically active compounds. The process breaks down the plastics quickly and efficiently, producing commercially viable yields of asperbenzaldehyde, citreoviridin, and mutilin.
New research from the University of Sheffield reveals genetically modifying rice to reduce stomata can make it more salt-resistant and survive in environments with high salt levels. This adaptation could help tackle food insecurity caused by climate change.
A modified Atkins diet high in fat and low in carbohydrates has been shown to reduce seizures by more than half when combined with standard drug therapy. The study involved 160 adults and adolescents with drug-resistant epilepsy, finding significant improvements in quality of life and behavior.
A global registry for gene-drive modified organisms could facilitate transparent communication, monitor ecological impacts, and inform local decision-making. Experts agree that a registry is necessary for the fair development, testing, and use of gene-drive technologies.
Researchers genetically engineered a microbial community that can convert CO2 into sugar and produce useful chemicals, effectively acting as a living carbon sink. The community, consisting of bacteria and cyanobacteria, produces chemicals with a negative carbon balance.
Researchers have developed chemically modified nanosheets that can effectively deliver drugs to diseased cells, reducing side effects. The nanosheets, made from molybdenum disulphide, can exchange natural thiols with attached ligands, allowing for targeted drug delivery.
A team of scientists analyzed ancient DNA from medieval German Jews and found that the Ashkenazi Jewish community was more genetically diverse than modern-day Jews. The study suggests that the founder event occurred before the 14th century, with a small population giving rise to the modern Ashkenazi Jewish population.
The study found that the Erfurt Jewish community was more genetically diverse than modern-day Ashkenazi Jews, with at least two distinct groups. The research team discovered that the founder event, which makes all Ashkenazi Jews today descendants of a small population, happened before the 14th century.
Scientists at the University of Illinois Urbana-Champaign have created alginate hydrogels that can endure the growth of bacteria, allowing them to synthesize essential enzymes. The modified hydrogels provided a stable platform for bacterial colonies to form and grow, producing important compounds like nisin.
A recent study found that science misinformation about genetically modified crops reached a quarter of a billion people globally. The majority of articles containing GMO-related keywords contained false information, especially on human health concerns, which had the highest readership.
Researchers evaluated modified CEUS using perfluorobutane for diagnosing hepatocellular carcinoma in high-risk patients. The study found no significant difference in sensitivity, specificity, or accuracy between modified CEUS and CT/MRI LI-RADS v2018.
Researchers report new findings from a landmark transplant, showing unexpected heart conduction measures that did not contribute to failure. The study suggests genetic modifications made to the pig's heart were not responsible for causing these changes.
Scientists at NTU Singapore have successfully modified a plant protein to increase vegetable oil yield. By improving the binding affinity of WRI1, the team was able to enhance oil accumulation in seeds by 15-18% under laboratory conditions.
Researchers describe how oxygen levels in the blood are detected using specialized mitochondria in glomus cells. A study on genetically modified mice reveals that a functional electron transport chain is crucial for this process, which has implications for respiratory depression and diseases.
Research reveals that common gut bacteria enhance cocaine effects in mice by consuming glycine, leading to behavior abnormalities. Supplementing glycine or using a genetically modified bacteria reduces response to cocaine, demonstrating its role as an addiction mediator.
Researchers genetically modified mice to develop a similar disease to humans, identifying previously unknown mechanisms and potential therapeutic targets. The study found that reduced adhesion between cardiac muscle cells leads to scarring and arrhythmia, providing new insights into the disease.
Researchers found a longer PR interval and prolonged QT duration in genetically modified pig hearts after transplantation into humans, indicating signs of electrical disease. The study provides a foundation for future research to better understand xenotransplantation's effects on the heart's electrical system.
The University of Missouri has earned an $8 million grant from the National Institutes of Health to expand its National Swine Resource and Research Center. The center will support research using genetically modified pigs to study human diseases, with a focus on therapies that can be translated from pig models to humans.
Researchers develop two-stage approach converting mixed plastic waste into polyhydroxyalkanoates, a family of bioplastics suitable for medical materials. The hybrid process combines metal ion-promoted oxidation and bioconversion via genetically modified soil bacterium, enabling efficient recycling of commonly used plastics.
Researchers suggest that collisional erosion played a key role in shaping Earth's composition, contradicting initial building block theories. The findings have implications for the creation of other terrestrial planets outside the Solar System.
Researchers at Tufts University have created silk-based materials with exceptional water-repelling properties, surpassing those of current nonstick coatings. The modified silk can be molded into various shapes and forms, making it suitable for a wide range of consumer products and medical applications.
Researchers have genetically engineered human muscle cells to take up more sugar from the blood, reducing blood glucose levels by 20% in diabetic mice. The new tissue also shows promise for a single injection of tissue providing long-lasting glucose control.
Researchers have made a breakthrough in treating autoimmune diseases by using genetically modified CAR T cells to target and destroy harmful B cells. This innovative therapy has shown promising results in six young patients with severe forms of systemic lupus erythematosus, curing them completely without returning.
A genetically modified yeast strain can alter fermentation to create beers with intense tropical flavors and aromas. The strains increase the amounts of free thiols, which provide aromatic compounds found in hops.
A study by HKU Dentistry found that 'positive stress' can induce good changes in tooth stem cells, making them more resistant to injury and disease. The research team developed a preconditioning protocol that modified the cells genetically to mimic low oxygen conditions, which activated protective mechanisms.
A study published in PLOS ONE demonstrates that adding two 8-inch rubber bands to a surgical mask can improve its protective seal against particle exposure to N-95 levels. Thirty-one of 40 test subjects achieved modified masks that passed an N95 fit test, with improved results over time.
Researchers at RIKEN Center for Sustainable Resource Science found that adding ethanol to soil helps plants thrive during drought. The study showed that 75% of treated wheat and rice plants survived after rewatering compared to less than 5% of untreated plants.
A study found that mandatory labeling of genetically engineered foods in Vermont led to a 5.9% decrease in sales of GE-labeled products and a 2.5% increase in sales of non-GE products. However, after the law was repealed, sales of GE-labeled products increased by 6%, suggesting improved attitudes toward these products.
A large genomic study of snapper has identified three distinct oceanic snapper populations between Shark Bay and Ceduna in South Australia. The populations are genetically distinct and have unique geographical ranges, suggesting that snapper can make long-distance movements.