A new study by Wake Forest University researchers suggests that weight training with a low-calorie diet preserves lean muscle mass in older adults. Combining resistance training and calorie restriction resulted in less muscle loss and significant fat loss compared to cardio workouts or diet alone.
Researchers at NYITCOM found that short-term exposure to the Western diet can increase risk for developing diabetes and cardiovascular disease in females. The study revealed vascular damage and increased blood pressure, with females developing abdominal fat despite not being overtly obese.
A study from the University of Illinois shows that a post-weaning low-fat diet can reverse epigenetic changes caused by a maternal high-fat diet, reducing the risk of diseases such as type 2 diabetes. This suggests that dietary changes later in life can affect gene expression and metabolic pathways.
A BYU study with mice reveals stress can alter gut microbiota to resemble a high-fat diet, potentially contributing to gender-specific health disparities. Researchers found distinct changes in female mice's digestive microorganisms upon exposure to stress.
A new method targets the appetite-stimulating hormone ghrelin to prevent post-diet weight gain in mice. Mice treated with a virus expressing butyrylcholinesterase (BChE) gene therapy showed reduced weight regain and improved glucose tolerance after switching back to an unrestricted diet.
A study found that rats whose mothers ate a junk food diet during pregnancy had offspring that preferred fatty foods and showed altered brain reward circuitry into adulthood. A balanced diet in childhood seemed to reduce this preference, but did not eliminate it entirely.
A new study suggests that diet may be a crucial factor in the development of liver injuries in mice bred to consume high amounts of alcohol. The research found that mice on a diet of alcohol and water consumed less alcohol than those on an artificial sugar diet, resulting in greater liver injury.
The study found that modifying diet or adding moderate exercise can improve chemotherapy efficacy independent of weight loss. Obesity is on the rise in pediatric cancer patients, with lower survival rates and higher relapse rates compared to non-obese patients.
University of Tasmania researchers found that taking a 2-week break during dieting can lead to greater weight loss and less weight regain. The study showed participants who alternated between dieting and regular eating for 30 weeks lost an average of 8 kg more than those who continued with continuous dieting.
Researchers found that metabolic fingerprints from blood samples linked diet and nutrient biomarkers to type 2 diabetes risk in older women. Diet was shown to be a strong predictor of the disease, with fish, whole grains, and vegetable oils found to be protective.
Non-obese individuals with asthma may benefit from a healthy diet and regular exercise to control symptoms and improve quality of life. Studies have shown that exercise combined with a low-GI diet can lead to significant improvements in symptom control, with patients reporting a 50% reduction in asthma symptom scores on average.
A new study from North Carolina State University and the Union of Concerned Scientists found that SNAP benefits only cover 43-60% of the cost of a healthy diet. Lower-income households face significant challenges in affording a balanced diet. The study highlights the need for more affordable food options to support vulnerable populations.
A plant-based Mediterranean-style diet has been shown to provide the same medical benefits as popular reflux medications for treating laryngopharyngeal reflux. The diet led to a 62.6% reduction in Reflux Symptom Index, compared to 54.1% in patients taking proton pump inhibitors.
A ketogenic diet improved memory in aging mice and increased their chances of surviving to old age. The study suggests that the health benefits of BHB may go beyond memory and could affect tissues and organ systems.
A recent mouse study at UC Davis School of Veterinary Medicine reveals that a high fat, ketogenic diet increases median life span by 13% and improves quality of health in later life. The study also shows improvements in memory and motor function, as well as prevention of age-related markers of inflammation.
A new study by University of Missouri researchers found that physical activity changes diet preferences in male rats, but not female rats. The study suggests that environmental factors like exercise may influence how males and females eat.
A new meta-analysis finds that plant-based vegetarian diets are linked to lower total cholesterol and reduced risk of heart disease. The study highlights the benefits of a well-planned vegan diet, which can lead to weight loss, lower blood pressure, and improved cardiovascular health.
A recent Italian study confirmed that the Mediterranean diet reduces cardiovascular risk, but only in those with higher educational levels and/or greater household income. The study found no benefits for less advantaged groups, highlighting socioeconomic disparities in health.
Researchers find that a high-fat diet during pregnancy alters brain and endocrine system development in offspring, leading to anxiety and depression. A control group showed no such effects.
Researchers found that mice fed a high-fat diet exhibit withdrawal-like stress responses when switched to a low-fat diet, with dopamine levels impacted by stress signals. Blocking these signals normalizes the dopamine system, preventing binge-eating when the high-fat diet is reintroduced.
A new study published in the Journal of the American College of Cardiology found that not all plant-based diets are created equal. While a diet rich in whole grains, fruits, and vegetables reduces heart disease risk, one that emphasizes less healthy plant foods like sweetened beverages and refined grains increases the risk.
A study from Harvard T.H. Chan School of Public Health found that improving diet quality over time is associated with lower total and cardiovascular mortality. The study analyzed data from nearly 74,000 adults over a 12-year period and found that even modest changes in diet quality can significantly reduce the risk of death.
A Western diet high in fat and sugar has been shown to cause hepatic inflammation in mice, especially in males, with FXR-deficient mice being more susceptible. The study found that probiotics and bile acid receptor agonists may hold promise for preventing and treating hepatic inflammation and progression into advanced liver diseases.
Researchers identify JAK2-STAT3 cellular signaling pathway as key link between high-fat diet and tumor growth in the colon. The study provides insight into how diet influences cancer stem cell populations, potentially leading to new therapeutics.
A high-fat diet during pregnancy significantly increases breast cancer susceptibility in offspring for three generations, according to a Georgetown University Medical Center study. Genetic changes were observed in mammary tissue of high-fat diet progeny compared to control group's offspring.
A new study suggests that adhering to a Mediterranean diet with high levels of fish and fruit consumption can significantly reduce the risk of advanced colorectal polyps. The researchers found that even minimal consumption of two to three components of the diet was associated with half the odds of advanced polyps.
A new study published in the Journal of the American College of Nutrition found that vegetarian diets are more effective than conventional low-calorie diets in reducing body weight. Vegetarian diets also improve glucose and lipid metabolism, which is particularly important for people with metabolic syndrome and type 2 diabetes.
In a controlled study published in the Journal of the American College of Nutrition, participants who adopted a vegetarian diet lost nearly twice as much weight compared to those following a traditional diabetes diet. The study found that the plant-based diet led to greater reductions in subfascial and intramuscular fat.
Researchers found that participants with higher fasting plasma glucose levels lost more weight on a high-fiber, low-glycemic diet compared to those with lower blood sugar levels. Participants with high fasting blood glucose had lost an average of 9.4% body weight, while those with low fasting blood glucose had lost 4.1%.
A study of over 16,000 healthy adults found that those who followed a pro-vegetarian diet had a significantly lower risk of developing obesity. The researchers found that participants with the most vegetarian diet had a 43% reduced risk of obesity compared to those with the least vegetarian diet.
A study found that the DASH diet reduced gout incidence in men with similar dietary patterns, while a Western diet increased risk. The diet's emphasis on fruits, vegetables, and low-fat dairy products may help lower uric acid levels and reduce cardiovascular problems.
Researchers found that cinnamon supplements reduced belly fat, improved sugar and insulin levels, and increased antioxidant molecules in rats fed a high-fat diet. This suggests that cinnamon may mitigate the negative effects of a high-fat diet on cardiovascular health.
Researchers found that rats fed high-sugar diets experienced increased body fat mass, liver damage, and brain inflammation. A balanced diet was shown to mitigate these effects, highlighting the potential risks of sugar-laden diet products.
A new mouse study found that exposure to a high-fat diet in the womb and immediately after birth may increase offspring risk for nonalcoholic fatty liver disease later in life. The offspring of pregnant mice that consumed a high-fat diet developed liver fibrosis, a type of tissue scarring that is a sign of more serious disease.
Researchers found that removing serine and glycine from the diet of mice slowed lymphoma and intestinal cancer development. The special diet also made some cancer cells more susceptible to reactive oxygen species, which could boost conventional treatments' effectiveness. Next steps include clinical trials with cancer patients.
A study published in Scientific Reports found that a high-fat, high-carbohydrate diet rich in saturated fatty acids can weaken cartilage in joints, leading to osteoarthritis. The research suggests that diet may play a significant role in the onset of osteoarthritis, rather than wear and tear.
A mouse experiment revealed that hydroxytyrosol, a compound found in extra-virgin olive oil, can reverse markers of insulin resistance and non-alcoholic fatty liver disease. The study showed that hydroxytyrosol exerts a protective effect in the liver by improving enzyme activity and fatty acid composition.
A laboratory study found that a diet rich in folic acid and vitamins can impair the cognitive skills of offspring mice. The findings suggest that epigenetic changes in the paternal genome can be transferred to the next generation, potentially affecting human health.
A recent study found that high-calorie diets cause similar levels of bone loss in mice regardless of fat content. Glucocorticoid signaling in the skeleton plays a crucial role in diet-induced metabolic disturbances. Disrupting this signaling pathway may protect against obesity and related health issues.
Researchers found that a 65% decrease in liver volume and 46% reduction in hepatocyte size occurred in mice on a low protein diet. The liver's ability to regenerate itself was demonstrated after reintroducing a normal protein diet, with an 85% increase in liver volume.
Researchers found that cooking at home more often is associated with a greater dietary compliance and a lower risk of unhealthy eating. The study showed no increase in costs for eating a healthier diet, challenging common assumptions about income and education. Home-cooked meals were linked to diets lower in calories, sugar, and fat.
Researchers found that probiotics had little impact on microbial diversity and even impaired recognition memory in rats on a balanced diet. However, for rats fed a junk diet, probiotics positively changed the bacterial make-up in their digestive tract and benefitted brain function, preventing spatial memory loss.
A study published in Cancer Epidemiology, Biomarkers & Prevention found that women who consumed a diet high in sugar-sweetened drinks and processed meats during adolescence or young adulthood had a higher risk of premenopausal breast cancer. The researchers recommend consuming a diet rich in vegetables, fruit, whole grains, nuts, seeds...
Research published in The FASEB Journal found that mice fed nutrient-enriched diet during early life learned faster and were more motivated to obtain rewards. This study suggests that adolescence is a critical period for reversing negative effects of poor maternal diet during pregnancy.
A fasting-mimicking diet has been shown to reverse diabetes in mice by promoting the growth of new insulin-producing pancreatic cells. In humans, the diet also increased expression of a protein that accelerates insulin production in type 1 diabetes patients, suggesting potential for alleviating symptoms.
A new study suggests that a fasting-mimicking diet can reprogram pancreas cells in diabetic mice, enabling them to produce insulin and repair themselves. The researchers found that the diet triggered developmental reprogramming in the pancreas, rebuilding damaged areas and restoring function.
A phase III trial of a fasting-like diet shows significant benefits for 'at-risk' patients, reducing cardiovascular risk factors, inflammation, and fasting glucose levels. The regimen also shrunk waistlines and resulted in weight loss, with sustained effects even after returning to normal daily eating habits.
A study published in Epidemiology found that people on a gluten-free diet had higher concentrations of arsenic and mercury in their urine and blood compared to those who did not eat gluten-free. The study's findings suggest that a gluten-free diet may pose health risks due to increased exposure to toxic metals.
Eating whole grains improved gut microbiota diversity and short-chain fatty acid production, leading to reduced inflammation and increased memory T cells. The study also found modest effects on TNF-alpha production and immune cell function.
Researchers found that a high-sugar diet programmed flies' genes for longevity, causing long-term effects even after a healthy diet. The study suggests that dietary history has a lasting impact on health and may have implications for human lifespan.
A recent study published in Neurology found that adhering to a Mediterranean diet can help maintain brain volume in older adults. The study, which followed 967 Scottish people aged 70 for three years, revealed that those who followed the diet more closely retained more brain volume than those who did not.
A randomized, Phase III study will enroll 600 people with suboptimal diets to evaluate the effects of a specific diet on cognitive abilities and brain health. The MIND diet, which includes foods like fish, berries, nuts, and leafy greens, aims to improve brain health by developing new dietary guidelines.
A new study published in Applied Physiology, Nutrition, and Metabolism found that commercial weight loss programs including both diet and exercise resulted in greater improvements in metabolic syndrome. The research suggests that a synergistic approach to diet and exercise is essential for both weight loss and improved health outcomes.
Researchers found that certain human gut bacteria must be lost for a diet to be successful. A new approach identifies the organisms that help promote beneficial effects of a particular diet in humans.
Researchers found that a typical American diet increased the likelihood of obesity in offspring, even if mothers maintained a healthy weight. The study identified key biomarkers for detecting obesity risk, emphasizing the need for healthcare providers to discuss nutrition with pregnant women.
Research in mice shows that microbes communicate with hosts by sending metabolites that act on histones, influencing gene transcription. Diet composition impacts microbiome and epigenetic changes, with healthy diets promoting beneficial metabolite production.
Researchers at UAB found that a Mediterranean-style diet can reduce heart inflammation and failure in aged mice, as opposed to a Western-style diet high in omega-6 fatty acids. The study identifies key lipid signaling pathways involved in the disease process.
A Cleveland Clinic study found that a whole grain diet significantly lowers the risk of cardiovascular disease in overweight and obese adults under 50. Participants saw a three-fold improvement in diastolic blood pressure, reducing heart disease risk by nearly one-third.
A new study has found that faecal bacterial profiles can be used to predict which IBS patients are most likely to benefit from a low-FODMAP diet. The research identified differences in gut bacteria composition between those who responded and did not respond to the diet.
Researchers found that people who closely follow the Mediterranean diet, especially consuming fruit and caffeine, have a lower risk of age-related macular degeneration. A significant reduction in risk was observed among those with higher diet adherence scores, with only 39% developing AMD compared to 50% of non-adherents.