Articles tagged with Vitamin C
A recent study published in JAMA found that high-dose intravenous vitamin C did not reduce mortality and persistent organ dysfunction in patients with severe burn injury. Instead, the treatment may be harmful, suggesting alternative approaches for managing burn-related complications.
A study of 2,044 older Japanese adults found that lower vitamin C levels were associated with lower gray matter volume and reduced connectivity within the default mode network. Optimal vitamin C levels may support cognitive function, but further research is needed to explore the biological mechanisms.
A large meta-analysis of over 48,000 children found that well-planned plant-based diets can support healthy growth and even offer additional health benefits for children. However, the study also highlights risks of deficiencies in key nutrients such as vitamin B12 and zinc if not obtained through fortified foods or supplements.
A landmark study found that consuming vitamin C-rich foods like kiwifruit boosts plasma and skin vitamin C levels, improving skin thickness and stimulating renewal. Increasing daily vitamin C intake is recommended to support optimal skin function.
Researchers at the University of California San Diego have developed an electronic sticker that monitors vitamin C levels using sweat from fingertips, providing a convenient and low-cost alternative to current methods. The system is battery-free and can be manufactured at a low cost, making it potentially disposable and widely accessible.
A recent study by researchers at the University of Arizona Health Sciences found a two-way relationship between micronutrient deficiencies and chronic pain. People with severe deficiencies in vitamins D, B12, folate, and magnesium were more likely to have severe chronic pain.
Researchers discover vitamin C promotes epidermal thickening by reactivating genes essential for skin cell growth, suggesting a promising treatment for thinning skin in older adults. Vitamin C supports active DNA demethylation by sustaining TET enzyme activity.
Researchers from Korea University have developed a groundbreaking technique to transform fibroblasts into mature cardiomyocytes, holding promise for regenerative medicine in treating cardiovascular disease. The method combines fibroblast growth factor 4 (FGF4) with vitamin C to accelerate cell maturation and enhance function.
A randomized phase 2 clinical trial shows that adding high-dose, intravenous vitamin C to chemotherapy doubles the overall survival of patients with late-stage metastatic pancreatic cancer from eight months to 16 months. Patients also experience improved quality of life with reduced side effects.
A clinical trial found that two topical treatments, HPE and vitamin C, produce similar reductions in brown spot fractional area and improved skin luminosity and color evenness. The outcomes are comparable to those of more invasive treatments, suggesting a reliable and skin-friendly alternative to traditional cosmetic procedures.
A middle-aged man with scurvy was treated after neglecting his diet and stopping supplements due to financial constraints. He had multiple risk factors, including obesity, previous bariatric surgery, and low-income status, which led to vitamin C deficiency.
A new study led by UCL researchers found that older adults who are socially isolated are more likely to have an insufficient intake of key micronutrients such as vitamin C and vitamin B6. This is important as inadequate intake of these micronutrients puts people at greater risk of health problems as they get older.
US women between 20-44 years old have experienced declining vitamin A, C, and iron intake over the last two decades. This trend may have significant implications for maternal and fetal health. The study aims to identify these nutrient gaps and inform recommendations to improve intake.
A case study of a 65-year-old woman with scurvy highlights the need to consider vitamin C deficiency in patients with restrictive eating patterns and limited social support. Vitamin C deficiency is more common than expected, especially among those with low socioeconomic status or substance use disorders.
The wearable device monitors vital chemical levels in fingertip sweat, fueling its own energy and powering a suite of sensors. It can track glucose, vitamins, lactate, and levodopa levels without requiring physical activity or stimuli, offering a reliable health monitoring solution.
A new study found significant intake inadequacies for nearly all evaluated micronutrients, with iodine and vitamin E deficiencies being the most prevalent. The researchers estimated inadequate intakes were higher for women than men in some countries, highlighting a need for targeted dietary interventions.
A study published in The British Journal of Nutrition found that kiwifruit supplementation improved vitality and mood within four days, peaking around 14-16 days. Vitamin C intake also showed benefits, but to a lesser extent, improving mood until day 12.
Researchers found no significant improvement in primary composite outcomes, including organ support-free days and hospital survival, among hospitalized patients with COVID-19 who received intravenous vitamin C. The study suggests that vitamin C treatment may not be effective in improving patient outcomes for this population.
A global platform study has released results on the use of simvastatin to treat severely ill patients with COVID-19, showing a high probability of improving outcomes. In contrast, high-dose vitamin C was found to be ineffective and potentially harmful in critically ill patients, suggesting its use should be discontinued.
A subgroup analysis found that patients with an NPM1 mutation had a 48% reduced risk of death compared to those without the mutation. Patients receiving supplementation experienced lower rates of bacterial infections, bleeding, and inflammation during intensive chemotherapy.
Researchers found that antioxidants activate a mechanism forming new blood vessels in tumor cells, which can help them grow and spread. The study suggests that dietary supplements containing antioxidants may accelerate tumour growth and metastasis in cancer patients.
Two new studies published in Nutrients support the health benefits of regular watermelon consumption, finding higher intakes of dietary fiber, magnesium, and vitamins in watermelon consumers. Watermelon juice supplementation also protects vascular function during hyperglycemia, according to researchers.
Researchers found that vitamin C improves dendritic cell activation, promoting immune response and antigen presentation. This discovery may lead to more potent dendritic cell-based therapies against cancer.
A study led by Oregon State University found that cystic fibrosis patients who supplement their diet with vitamin C can derive greater benefits from vitamin E, resulting in reduced inflammation. The study suggests that high doses of vitamin C may be beneficial in inflammatory conditions.
A case report highlights the dangers of excessive vitamin D intake, with symptoms including abdominal pain, leg cramps, and kidney abnormalities. Doctors warn that hypervitaminosis D is on the rise and can lead to serious health problems if not taken safely.
A study in rats suggests that vitamin C supplementation can help preserve skeletal muscle after doxorubicin therapy, reducing oxidative stress and inflammation. The findings suggest vitamin C may represent a promising opportunity to reduce some of the drug's most debilitating side effects.
A new review of COVID-19 hospitalization data found no reduction in mortality for patients treated with vitamin D, vitamin C, or zinc. However, treatment with vitamin D may be associated with lower rates of intubation and shorter hospital stays.
A new study suggests that drinking 100% orange juice significantly reduces interleukin 6, a well-established marker of inflammation, in both healthy and high-risk adults. However, the results did not quite reach statistical significance for two additional inflammatory and oxidative stress markers.
A meta-analysis of randomized controlled trials found lactoferrin to have promising efficacy in reducing the risk of respiratory tract infections, including COVID-19. Lactoferrin may also play a beneficial role in managing symptoms and recovery for patients suffering from RTIs.
A study published in Archives of Physical Medicine and Rehabilitation found that 80% of people with spinal cord injury use complementary and integrative healthcare approaches. The most common reasons for use were general health and wellness, pain management, and to improve mobility and flexibility. However, there is a need for more res...
A new study reanalyzes the Sorby vitamin C experiment, a landmark trial that determined the minimum vitamin C requirements for preventing scurvy. The analysis suggests that the recommended daily intake of 45mg may be too low to prevent weak scar strength.
Scientists at the La Jolla Institute for Immunology have discovered that Vitamin C and TET proteins can work together to generate stable induced Tregs, which could potentially treat autoimmune diseases. The study reveals an intriguing connection between TET enzymatic activity, Vitamin C and IL-2/STAT5 signaling.
A study in rats found that low womb oxygen can impair adult brain function and memory. Vitamin C supplements during pregnancy protected the offspring's brain health. The results suggest a potential preventative medicine approach for long-term brain health.
A new University of Washington study found that bleeding gums on gentle probing and retinal hemorrhaging are associated with low vitamin C levels in the bloodstream. Increasing daily vitamin C intake helped reverse these bleeding issues.
Researchers suggest that vitamin C therapy for COVID-19 may be effective in certain populations, but its success could be hindered by low levels of the natural transporter needed to get the vitamin inside cells. Factors such as age, race, and genetic variations of the transporter also impact effectiveness.
A new study published in the Journal of Nutrition suggests that vitamin C consumption is linked to higher skeletal muscle mass in older adults. The research, which analyzed data from over 13,000 participants, found that those with the highest amounts of vitamin C had the greatest estimated skeletal muscle mass.
A 12-week study by Oregon State University researchers found that taking a daily multivitamin and mineral supplement with zinc and high amounts of vitamin C reduced the severity and duration of illness symptoms in older adults. The supplement improved vitamin C and zinc levels in the blood, which are important for immune function.
Researchers at UC San Diego developed a non-invasive wearable device to track vitamin C levels in sweat, enabling personalized nutrition and dietary adherence. The device has shown high sensitivity and potential for detecting nutritional deficiencies and supporting recovery from COVID-19.
A combination of fasting-mimicking diet and vitamin C has been found to delay tumor progression and even cause disease regression in multiple mouse models of colorectal cancer. The treatment works by regulating iron levels and molecular mechanisms involved in oxidative stress, making it a safer alternative to toxic treatments.
A recent study published in Nutrients suggests that daily multivitamins with high doses of vitamin C and vitamin D can help fight off infections. The researchers recommend taking 200mg or more of vitamin C and 2,000 international units of vitamin D to support immune function.
A meta-analysis of five controlled trials including 471 patients found that vitamin C administration shortened ventilation time by 25% on average, with the effect dependent on the severity of illness. Vitamin C has been shown to have various biochemical effects, including influencing cardiovascular and energy metabolism.
A new pediatric study found that treating septic shock with a combination of vitamin C, vitamin B1, and hydrocortisone reduces mortality in children. The treatment resulted in mortality rates of 9% at 30 days compared to 28% in control groups.
Researchers at McMaster University discovered that scurvy, a disease caused by vitamin C deficiency, still exists in Canada. The study found 52 patients with low Vitamin C levels, including 13 with diagnosed scurvy and 39 who tested positive but lacked symptoms.
A recent global trial has found that high-dose intravenous vitamin C, thiamine, and hydrocortisone therapy does not improve survival rates or treatment outcomes for patients with sepsis. The study refutes previous claims of the effectiveness of this 'Vitamin C cocktail' in treating sepsis.
A randomized clinical trial of 200 patients with septic shock found that combining vitamin C, hydrocortisone, and thiamine did not significantly improve survival rates over seven days compared to hydrocortisone alone. The study's findings were released in conjunction with the Critical Care Reviews Meeting 2020.
A randomized clinical trial found that high-dose intravenous vitamin C did not reduce organ failure, inflammation, or vascular injury in patients with sepsis and acute respiratory distress syndrome (ARDS). The study's limitations include underpowered detection of differences and insufficient dosage.
A new study published in JAMA found that treating septic patients with intravenous vitamin C infusions significantly reduced mortality and improved recovery times. The trial showed a 30% reduction in mortality at day 28 compared to the placebo group, and patients spent three fewer days in the ICU.
Researchers found that antioxidants like vitamin C can block toxicity caused by hexavalent chromium in human cells, which could lead to a new treatment method for water contamination. The study suggests an oxidative mechanism is responsible for the contaminant's toxicity, and treating water with antioxidants may prevent it.
A systematic review suggests that vitamin C administration can decrease ICU length of stay by an average of 7.8%, with higher doses reducing duration by up to 8.6%. Vitamin C's role in energy metabolism and cardiovascular system makes it a promising intervention for critically ill patients.
Research suggests that metabolic syndrome patients require higher amounts of vitamin C to counteract the effects of antioxidant depletion. A diet high in saturated fat leads to chronic inflammation, which can trigger metabolic syndrome and impair gut function. Eating fruits and vegetables daily can help restore balance.
A randomized controlled trial found that vitamin C supplementation reduced harm to infants' lungs caused by smoking during pregnancy. Infants whose mothers took 500mg of vitamin C in addition to their prenatal vitamin had significantly better lung function at three months of age, according to the study.
The kiwifruit's ancestors duplicated their DNA in two events to produce extra copies of genes, including those for creating and recycling vitamin C. This allowed the fruit to thrive with increased vitamin C production.
A recent study has found that pregnant smokers who take daily vitamin C supplements may have babies with improved lung function and reduced risk of wheeze. The researchers measured forced expiratory flows in infants born to mothers who smoked, and found significant differences in lung function at three months and one year.
Researchers at The University of Tokyo's Institute of Industrial Science have developed a new probe to track vitamin C levels in the body using fluorescence. This breakthrough allows for precise monitoring of ascorbic acid concentrations, which has potential applications in cancer treatment.
Research in mice and tissue cultures suggests that vitamin C enhances the killing power of first-line TB drugs, isoniazid and rifampicin. The combination reduces organ burdens faster than the drugs alone, with a potential to shorten TB chemotherapy duration.
A study found that vitamin C activated the enzyme TET2 in mice with genetic mutations that reduce its function, leading to the death of leukemia stem cells. High-dose vitamin C treatment was also shown to suppress the growth of cancer stem cells from human patients implanted in mice.
A clinical trial found that brain and lung cancer patients can safely receive high doses of vitamin C, which increases sensitivity to radiation and chemotherapy. The study also showed that altered iron metabolism in cancer cells leads to increased death caused by vitamin C.
A study found that higher doses of vitamin C, particularly 8g per day, significantly reduced the duration of common cold symptoms. The findings suggest a dose-dependent effect and could lead to improved treatment options for individuals with common colds.
A diet rich in carotenoids and vitamin C may protect against lung cancer, according to a study. High intakes of these antioxidants were associated with a lower risk of squamous cell carcinoma, adenocarcinoma, and small cell carcinoma in both smokers and nonsmokers.
A systematic review of 14 randomized trials found that vitamin C significantly reduced the incidence of post-operative atrial fibrillation in high-risk patients. The review also showed that vitamin C decreased hospital stay length and intensive care unit stay, with intravenous administration having greater effects.