Researchers found that patients with higher epicardial adipose tissue volume had older age, higher body mass index, and greater myocardial injury after a heart attack. Non-invasive quantification of EAT volume using cardiovascular magnetic resonance could play a decisive role in cardiovascular risk assessment.
Researchers discovered subtypes of chondrocytes that transform into bone-building cells, regulating bone growth and vascularization. The study found that these cells secrete Thbs4 to induce blood vessel formation, shedding insights for treating defective angiogenesis.
Researchers at Cold Spring Harbor Laboratory use CRISPR to edit the goldenberry plant, reducing its growth by 35% and making it suitable for denser farming. The team hopes to breed plants with desirable traits such as fruit size and disease resistance.
Mass General Brigham's new AI company, AIwithCare, has developed a software platform that leverages generative AI to screen patients for clinical trial eligibility. The tool, RECTIFIER, was found to accurately identify eligible patients and enroll them in clinical trials at a lower cost than traditional methods.
Chromatin accessibility maps reveal that MDS stem cells gradually lose their normal identity and acquire characteristics typical of myeloid progenitors. A 'progenitor score' developed by the team tracks cell movement toward a progenitor-like state, correlating with disease severity and prognosis.
A new study reveals that global food insecurity analyses systematically underestimate hunger, with significant implications for humanitarian aid allocation. The researchers found that 66.2 million people, or one in five, who suffer from hunger may go uncounted due to underestimation.
A study found that only 6% of FDA-approved drugs reflect the US racial and ethnic makeup, with a decline in Black and Hispanic enrollment between 2021 and 2023. The researchers recommend setting diversity goals at preclinical stages and collecting biological samples to understand how people's bodies react to medications.
Researchers have developed a method to control protein levels inside different tissues of a whole, living animal for the first time. The technique uses a plant hormone called auxin to precisely regulate protein levels, allowing scientists to study the molecular underpinnings of ageing and disease.
Researchers discovered three new species in a previously unknown genus, lacking genes linked to the group's complex lifecycle. These bacteria possess photosynthetic genes, revealing widespread capabilities among this group.
A comprehensive analysis of 383 US cities found common patterns of isolation and segregation, with wealthy suburban areas and poorer downtown zones often having limited interactions between residents. Researchers recommend zoning incentives and strategic development to encourage greater diversity and social mixing.
Researchers found a mosasaur tooth in North Dakota that revealed the giant reptile's ability to thrive in freshwater rivers. The study used isotope analyses to show that mosasaurs inhabited riverine environments in their final million years before extinction.
Researchers at Osaka Metropolitan University have developed a new stem cell medium using only canine-derived genes, enabling the stable cultivation of canine induced pluripotent stem cells. This breakthrough reduces cross-species contamination risks and paves the way for clinical applications in dogs.
A large meta-analysis of over 48,000 children found that well-planned plant-based diets can support healthy growth and even offer additional health benefits for children. However, the study also highlights risks of deficiencies in key nutrients such as vitamin B12 and zinc if not obtained through fortified foods or supplements.
A University of Rhode Island professor studied natural selection in Anolis lizards impacted by hurricanes, finding longer limbs and larger toepads increase survival rates. This study confirms hurricanes as a source of episodic natural selection with lasting evolutionary effects.
Researchers discovered the biosynthetic pathway of glycitein, a key soybean isoflavonoid, and its role in plant immunity. They found that GmIF6H1 enzyme catalyzes the production of glycitein, which acts synergistically with glyceollins to defend soybeans against infection by Phytophthora sojae.
The German Federal Institute for Risk Assessment (BfR) is launching a new study module to investigate the influence of parental nutrition on children's eating habits. The study aims to provide insights into how plant-based diets of parents affect the eating habits and food consumption of children.
Researchers simulated the Josephson effect using ultracold atomic gases and observed characteristic Shapiro steps, confirming its universality. The findings enable the study of quantum effects in atomic systems, paving the way for 'atomtronics' and potential applications in quantum computing and medical diagnostics.
A new study reveals the molecular clues behind cassava's better heat handling than potato. Cassava maintains photosynthesis and hormonal balance to withstand heat, whereas potato relies on energy-costly stress repair mechanisms.
The loss of submerged macrophytes, which trap arsenic, can lead to its release into the water upon plant death. This study highlights a previously underestimated process, revealing an overlooked pathway for arsenic contamination.
A new study estimates that the Amazon rainforest could lose up to 38% of its area by the end of the 21st century due to land use changes and climate change. The research, published in PNAS, suggests that abrupt transitions from dense forest coverage to savannah-like landscapes pose a significant risk to the ecosystem.
A new system, Coded Aperture Compressive Temporal Imaging (CACTI), uses AI to overcome traditional limitations in high-speed photography. The system achieves exceptional image quality while reducing data requirements, making it useful for studying transient physical processes.
A 150-day microcosm experiment simulated acid rain, weakening native microbial networks and creating space for invasive pathogens. The study found that surviving populations underwent major genomic remodeling, evolving into more persistent and virulent strains.
A novel acid-promoted radical substitution strategy achieves selective synthesis of m-phenylenediamine compounds from aromatic amines, offering a more efficient and regioselective approach than current methods. The reaction exhibits good substrate versatility and functional group compatibility.
The study reveals a relationship between X-ray luminosity and rotation velocity, with the accretion system changing during the faint phase. The height of the accretion column was found to change with the 10-year flux modulation.
Research finds that automatic patient outreach significantly increased the number of patients who completed advance care planning documentation. The study, published in Annals of Internal Medicine, suggests that health systems can implement automated mechanisms to promote advance care planning conversations and improve patient outcomes.
Single-crystal HfB2 nanorods exhibit enhanced mechanical properties, with a 4.1% increase in hardness and 37.6% improvement in fracture toughness. The nanorods also demonstrate excellent ablation resistance, impeding oxygen atom penetration and reducing mass ablation rates.
A study published in The BMJ found a 25% decline in diversity language in NIH grants from January 2024 to June 2025. Researchers analyzed 17,701 grants and found that words related to diversity, equity, and politics were deleted at a 10-fold higher rate in 2025.
Microplastics leak a complex mixture of dissolved organic chemicals that evolve over time, especially under sunlight. The study provides the most detailed molecular-level view to date of how this microplastic-derived dissolved organic matter forms and transforms in natural waters.
Researchers found that wildfires can convert chromium 3, a benign form in rocks and soil, into the carcinogenic chromium 6. Soils from summits contained high levels of chromium 6 when burned at temperatures above 750 F, which could taint groundwater for up to 2.5 years. The study highlights the need for better understanding of fire's i...
A new study found that rising temperatures are driving changes in polar bear DNA, which may help them adapt to increasingly challenging environments. The researchers discovered that genes related to heat-stress, aging, and metabolism are behaving differently in polar bears living in southeastern Greenland.
A new study found that calcium accumulation in breast arteries and its progression on mammograms can predict future cardiovascular disease. Women with more severe calcification and those whose calcification worsened over time had a higher risk of heart-related events, such as heart attack, stroke, and death.
A UBC Okanagan study found that microdosing psychedelics temporarily improves mood, creativity, and wellbeing, but these effects do not persist on non-dosing days. The study, tracking over 1,435 participants from 49 countries, suggests that microdosing may 'reactivate' or build upon prior effects of larger-dose psychedelic experiences.
A new blood biomarker, neurofilament light (NFL), has been shown to accurately predict the extent of brain damage after a cardiac arrest. This breakthrough discovery may transform care for patients in intensive care units, allowing for more informed decisions about their treatment.
A third of teenagers use AI companions for social interaction, with some reporting more satisfying conversations than humans. Experts caution against problematic chatbot use as a new environmental risk factor, particularly among vulnerable populations.
A new single-dose oral medication called zoliflodacin shows promise as a treatment for antibiotic-resistant gonorrhoea, with over 90% of infections cured at genital sites. The medication is well-tolerated and has the potential to improve global efforts to control drug-resistant gonorrhea infections.
A UBCO study found that resilience is shaped by supportive communities, not individual traits. Community-based strategies and place-based interventions are crucial for effective suicide prevention.
A study analyzing 1000 biomedical articles found that almost 1 in 5 'recent' references are at least 10 years old, suggesting the term is used more as a narrative device than a measure of time. Citation patterns varied across medical specialties, with some fields citing older references than others.
Research from University of Vermont reveals exposure to Canadian wildfire smoke worsened asthma symptoms in children in the US Northeast. The study found that smoke from hundreds of miles away affected children's health, highlighting growing health risks for the region as climate change fuels more smoke-filled summers.
The discovery of a 66-million-year-old tooth in North Dakota, USA, reveals that mosasaurs may have hunted in freshwater environments as well as seas. The analysis of isotopes in the tooth's enamel suggests that the mosasaur preyed on freshwater animals and lived in a river-like area formerly connected to an ancient sea.
A new study evaluates four microbial aerosol samplers and finds that membrane filtration produces the highest collection efficiency for particles at or below one micrometer. The study suggests that choosing the right sampler is crucial for accurate airborne pathogen detection.
The grant aims to increase individual screenings and change how health systems embed evidence-based screening practices into everyday operations. PA-CARES will work with trusted organizations in 28 counties with the lowest screening rates to implement effective screening options and facilitate timely linkage to care.
Muthu Wijesundara, a UT Arlington researcher, has been honored as a National Academy of Inventors fellow. He is recognized for his innovations in robotic exoskeletons and advanced medical devices, which aim to improve healthcare outcomes.
A Phase III trial has demonstrated the survival benefit of proton therapy compared to traditional radiation therapy for oropharyngeal cancer patients, with improved overall survival at five years. Proton therapy also resulted in reduced toxicities and feeding tube dependence, highlighting its potential as a standard treatment option.
A study published in the journal Children found that improving access to safe drinking water can reduce the odds of stunting by about 20%. The researchers analyzed data from over 3,500 children and found that clean water access had a stronger impact on child growth than sanitation.
A new species of roundworms, Diplolaimelloides woaabi, has been discovered in the Great Salt Lake, characterized by its unique features and potential role in the lake's ecosystem. The discovery raises questions about how the worms arrived in the lake and their adaptation to highly saline environments.
The study found that the investigational vaccine produced an immune response in 74% of participants and was safe and well-tolerated. A Phase 2 study is planned to evaluate the vaccine's efficacy, offering new hope for triple-negative breast cancer treatment.
Researchers have developed a nearly 100 times smaller device that can efficiently control lasers required for thousands of qubits, unlocking potential for larger quantum computers. The device uses microwave-frequency vibrations to manipulate laser light with extraordinary precision.
A new review evaluates biological strategies to improve the efficiency of photosynthesis, highlighting promising solutions such as engineering Rubisco enzyme and developing cooperative crops. The research aims to address global challenges in agriculture and ensure food security for the world's population.
A patient with refractory synovial sarcoma was the first in Arizona to receive TECELRA, a genetically modified autologous T cell immunotherapy. The treatment showed early signs of tumor shrinkage and has been shown to benefit over 40% of patients with similar cancer types.
Dr. Mintz brings exceptional clinical care, research, and education expertise to the role. He will lead transformative initiatives in perioperative operations, improving financial performance, employee satisfaction, quality, safety, and patient experience.
A prospective multicenter trial validated an improved method for predicting treatment benefits in hormone receptor-positive metastatic breast cancer with bone metastases. Metabolic change assessed by FDG-PET/CT accurately predicted progression-free survival as early as 12 weeks after treatment initiation.
CEMIP is associated with the breakdown of myelin, a protective sheath around nerve cells. Elevated levels of the enzyme inhibit myelin regeneration in people with multiple sclerosis. Researchers hope targeting CEMIP may promote central nervous system repair and slow disease progression.
James Schwob, a professor at Tufts University School of Medicine, has been named a fellow of the National Academy of Inventors. His research focuses on the mechanisms that regulate neural development using the peripheral olfactory system as an ideal model for neuroregeneration and therapeutic approach for age-related olfactory loss.
Researchers have discovered that jarosite selectively captures bromine under Mars-like conditions, offering insights into the Red Planet's aqueous past and halogen cycling. The study reveals a clear trend: bromine is strongly favored over chlorine for incorporation into jarosite, with specific temperature-dependent effects.
L. Jay Guo, University of Michigan professor, recognized for scalable nanopatterning technology enabling next-gen flexible electronics and structural color applications. His work has attracted interest from major companies like Samsung and Toyota.
A new study suggests that indoor lighting can strongly influence listeners' experiences while listening to music. The research found that warm white lights were most effective in evoking positive emotions, while blue lights had the least positive response. These findings have implications for improving well-being and mood regulation in...
Florida Atlantic University's College of Engineering has received a $600,379 grant to advance technology targeting harmful algal blooms in Florida's waterways. The project aims to develop novel 3D-printed adsorbent materials for efficient phosphate removal.
Researchers investigated how AI can aid clinicians in analyzing medical images and found that while AI improves diagnostic accuracy, it also requires careful consideration of explanations and trust levels. The study's findings highlight the importance of balancing ease of use with utility in designing AI systems for clinical applications.
Researchers at MIT have discovered a simple way to make carbon capture more efficient and affordable by adding a common chemical compound called tris to capture solutions. This innovation can stabilize the pH of the solution, allowing the system to absorb triple the amount of CO2 at relatively low temperatures.
Scientists have discovered a shape-shifting molecular valve in PANX1, a cellular gate that controls the flow of chemical messages. Researchers found that a common antimalarial drug can enhance or inhibit this gate's activity, paving the way for precision therapies.