Research published by the American Psychological Association found that talking about what you oppose instead of what you support makes others more open to your views. Small changes in wording can impact receptiveness to messages.
Researchers have created an mRNA system that activates therapeutic genes in specific cell populations, potentially leading to safer and more precise cancer treatments. The system uses microRNAs to recognize cancer cells and shuts off the treatment if it's not needed, reducing toxicity and expanding mRNA therapy's reach.
A three-year study by the University of Plymouth is investigating why fewer overseas-trained doctors become GPs and consultants in the NHS. The project seeks solutions at individual, trust, and national levels to support international medical graduates' career progression.
Researchers at Washington State University have found a way to modulate a key interaction that allows herpes viruses to enter cells. By targeting this critical interaction, they were able to significantly block the virus' ability to invade cells, paving the way for potential new antiviral treatments.
Jeonbuk National University researchers examine how different seasonings shape kokumi perception in doenjang soup, influencing consumer acceptance. They found that umami is a major sensory driver of kokumi perception and can be enhanced to improve the flavor quality of fermented foods.
Keck Medicine of USC hospitals, including USC Norris Cancer Hospital and Keck Hospital, have received the Top Teaching Hospital award from The Leapfrog Group for exceptional patient safety and quality. This is the first time two hospitals within the health system have received this honor simultaneously.
Researchers have discovered that certain gut bacteria with similar structures to the protective layer of nerves can misdirect the immune system and cause it to attack its own nervous system. This mechanism accelerates the progression of multiple sclerosis.
Researchers discovered glioblastoma cells use PRDM9 to survive chemotherapy and regrow tumors. By blocking PRDM9 or cutting off cholesterol supply, persister cells can be wiped out, improving survival in mice. This breakthrough offers new strategies for treating the deadliest brain cancer.
A study by University of Zurich researchers has shed light on the mechanisms that maintain homeostasis with mucosal fungi. The team discovered that the fungus Candida albicans uses a toxin called candidalysin to survive in the mouth, and that interleukin 17-mediated immunity prevents it from growing out of control.
A novel AI tool called V2P has been developed to identify not just genetic mutations but also the diseases they may cause. The method accelerates genetic diagnostics and aids in discovering new treatments for complex and rare diseases by predicting disease outcomes.
A team of MIT engineers developed a deep-learning model that predicts how individual cells will fold, divide, and rearrange during a fruit fly's earliest stage of growth. The model achieved 90% accuracy in predicting the movement of 5,000 cells over the first hour of development.
Researchers found that abundant mRNA molecules tend to cluster together in brain neurons, driven by chance overlap rather than coordinated movement. This discovery provides insights into how neurons manage genetic instructions and supports learning and memory, with potential implications for conditions like Fragile X syndrome.
A new American Heart Association scientific statement suggests that combination pills combining two or more medications may help adults with high blood pressure achieve optimal blood pressure goals more quickly, reduce their risk of heart attack and stroke, and improve long-term health. Currently, most people need two or more medicatio...
Researchers at Linköping University have successfully created electrodes from conductive plastics using visible light, eliminating the need for toxic chemicals. The technology allows for the creation of flexible electronics and biocompatible sensors on various surfaces, including skin.
A new study found that Italian bears living in areas with many villages have evolved to become smaller and less aggressive. The researchers attributed this change to the removal of more aggressive bears by humans, which led to a selection for behavior-related genetic variants associated with reduced aggressiveness.
A recent study from the University of Eastern Finland found that buying second-hand gifts involves a deliberate decision-making process, often driven by eco-friendly values. The study suggests that consumers tend to deliberate more when buying second-hand furniture or clothing, but less for items like books.
A national poll reveals that many parents struggle to provide guidance on healthy eating habits for their teens, particularly during the holiday season. The poll found that only half of parents report their teen eats three meals a day, and nearly a third report their teen snacks throughout the day.
Researchers at Osaka Metropolitan University engineered yeast to produce 122 times more 2,3-butanediol in high-concentration environments. Gene expression analysis revealed the crucial role of proteasome and peroxisome activation in tolerance.
A team of researchers has discovered a distinct group of hot Jupiters whose circular orbits contradict the expected timescale for tidal migration. These planets exhibit characteristics consistent with disk migration, such as primordial alignment and planet multiplicity, suggesting they formed smoothly within the protoplanetary disk.
Lab studies found that a combination of THC and CBD kills ovarian cancer cells without harming healthy cells. The compounds may prevent metastasis and have minimal toxic effects, making them a promising alternative to current treatments.
A reduced pledge by Canada to the Global Fund could lead to decreased success in controlling tuberculosis and HIV/AIDS in the country. The authors of an editorial urge Canada's government to invest in improving social determinants of health and implement disease-specific suggestions to address these pressing global health issues.
Research shows that 77% of severely injured children are transported or transferred to pediatric trauma centers, highlighting the need for improved access and evidence-based strategies. Variability in access exists across Canadian provinces, with some areas having higher access than others.
Researchers developed novel fluorescent diatomite-based carbon dot composites for dual-mode high-resolution imaging of latent fingerprints. The synthesized Dye-CDs exhibited high photostability and selectivity in daylight and fluorescence visualization.
A research team has discovered a new regulatory mechanism underlying grapevine cold tolerance, involving the ubiquitin switch VaMIEL1 and its impact on stress responses. The findings reveal an integrated system integrating transcriptional control and redox balance during cold adaptation.
A nationwide survey found high prevalence of OCD (2.43%) and severe impact on daily life, with significant comorbidity with other mental disorders. Treatment gaps were also identified, with only 6.74% seeking help after an average delay of over 10 years.
A 20-year study analyzed 39 cases of primary ovarian leiomyoma, a rare type of benign tumor that develops in the ovary. The study highlights the limitations of imaging in diagnosing these tumors and emphasizes the importance of precise diagnostic methods.
A UCL–SCUT–Imperial team uses high-energy synchrotron X-ray radiography to examine AZMBs, finding that densely packed cells have better anode behavior than textbooks suggest. The imaging platform will be used to screen new chemistries and directly visualize where damage occurs.
The study demonstrates the auditory cortex's ability to integrate fine-scale and coarse-scale temporal cues during synchronization, with better performance in macaques compared to the middle glandular body. The nonlinguistic oddball paradigm shows promise for clinical applications in psychiatric disorders and future research should exp...
A new study suggests that AI chatbots like ChatGPT can help reduce mental health stigma by making people feel more comfortable seeking support. The research found that believing the tool is effective plays a key role in reducing concerns about external judgment and increasing its perceived effectiveness.
A new study by Edith Cowan University found that AI technologies boost marketing agility, leading to stronger stakeholder engagement. The research also highlights the importance of adapting to AI adoption to achieve sustained competitive advantage.
Researchers have developed flexible perovskite solar modules with power conversion efficiency (PCE) over 20% using acid-treated carbon nanotubes as window electrodes. These modules exhibit improved stability, bendability, and scalability, making them a promising solution for sustainable energy systems.
Associate Professor Shefaly Shorey has been appointed Editor-in-Chief of Midwifery, a leading international journal in midwifery and maternal health. She aims to champion high-quality, compassionate care through evidence-based practice, honours dignity, strengthens equity.
A new global ocean data assimilation system has been developed to improve the accuracy of sea-surface temperature and sea-level anomaly forecasts. The YHGO platform integrates a fully nonlinear and non-Gaussian data assimilation method with a mass-conserving ocean model, leading to improved performance compared to existing systems.
Researchers have discovered a room-temperature Mott insulator in the kagome compound Nb₃Cl₈, which provides a highly tunable platform for exploring strong electron correlations. The material exhibits a thermally induced melting behavior of its energy gap, a hallmark of a Mott insulator.
A research team proposes a 'three-in-one' modeling strategy to tackle the complex electromagnetic environment of future space-air-ground networks. The framework integrates digital twin technology and agent-based modeling to capture dynamic interactions and understand signal intent.
The study reveals a 81m dinosaur trackway as the longest known in China and the fastest running theropod trackway from the Cretaceous period. The analysis indicates that medium-sized theropods ran at speeds of up to 45 km/h, while large theropods walked at slower speeds.
Research shows that companies with strong environmental, social, and governance track records perform better after adopting rigorous auditing standards. Investors view ESG practices as a signal of corporate quality, amplifying the benefits of transparent auditing.
A team of Chinese scientists has developed a new model, GoMars, to simulate Martian dust cycles and global-scale dust storms. The 50-year simulation predicts consistent seasonal and spatial patterns, including the timing of peak dust devil lifting and intense dust devil activity in Amazonis region.
A new study finds that traffic-related pollution causes immediate changes in the atmospheric electric field, while particulate matter affects it more slowly. The research also identifies a 'weekend signal' where reduced emissions lead to a weakened electric field.
Researchers developed a method that characterizes collective dynamics of neural activity using principles from thermodynamics. They found that neurons dynamically reshape their interactions during behavior and that the brain's internal temporal asymmetry shifts during task engagement, shedding light on efficient computation.
Researchers have proposed a new approach to boost sulfur use in solid-state batteries using tandem catalysis. This method achieves stepwise S8 reduction to Li2S via intermediate Li2S2, significantly reducing conversion energy barriers and exploiting deep sulfur conversion capacity.
The Hebrew University-Hadassah School of Dental Medicine has established a new center dedicated to providing quality dental care for people with physical, cognitive, and complex medical conditions. The center will offer holistic, multidisciplinary care under one roof, serving approximately 30-40 patients daily.
Researchers from Duke and Duke-NUS are investigating genetic features controlling infection susceptibility across populations to develop new treatments. They will compare cohorts in Singapore and the US, analysing how genetic variants shape disease vulnerability.
Dr Aldona Mzyk's project uses quantum sensors to track how immune cells interact with tumours, enabling the development of improved patient-tailored cancer therapies and earlier diagnosis tools. The research aims to overcome current cancer immunotherapies' failure in solid tumours by controlling metabolic changes.
A new study found that highly educated, Western European millennials have the most digital concerns, with individuals having higher levels of digital literacy being the most affected. The research also found that people's perceptions of digital harm are heightened by their level of digital exposure and knowledge.
Researchers analyzed two water spinach cultivars to understand how specific root cells contribute to cadmium fixation and transport. The study identified key gene expression profiles and structural differences in root cells, highlighting the complexity of plant response to heavy metals.
A new Fe/C composite catalyst rapidly degrades sulfamethoxazole with up to 94.6% removal efficiency, effective across a wide pH range and in complex soil environments. The catalyst's high stability and strong radical production make it a scalable solution for environmental remediation.
Scientists from Tokyo Metropolitan University have re-engineered the Lattice-Boltzmann Method to store certain data, reducing memory usage and overcoming a key bottleneck. The new algorithm achieves significant accuracy and stability in simulations of fluids and heat.
A new study shows that achieving remission of prediabetes significantly reduces the risk of heart attack, heart failure, and premature death. Long-term data from over 2,400 people with prediabetes reveal a 50% lower risk of cardiovascular death and hospitalization for heart failure.
Research from King's College London reveals that reversing prediabetes through lowering blood sugar levels significantly reduces the risk of heart problems and death. People who achieved remission had a 58% lower risk of cardiovascular death, while those with normalised glucose levels saw a 42% reduction in major adverse events.
Researchers trained AI systems on data from two cultural groups playing a video game, finding that the agents learned and applied the group's degree of altruism. This approach, called inverse reinforcement learning, more closely aligns with human development and learning, where values are 'caught' rather than 'taught'.
China's Ecological Protection Redline system has identified 32% of the nation's land as crucial ecological space, safeguarding major ecosystems and wildlife species. Recognizing these areas as 'other effective area-based conservation measures' (OECMs) could close the remaining gap to achieving 30x30 without creating new parks.
Researchers have created a three-dimensional human heart organoid that can replicate atrial fibrillation, a condition affecting millions worldwide. The organoids' ability to study heart development, diseases, and drug responses has the potential to revolutionize arrhythmia treatment.
A survey of urban forests in western Oregon found no connection between mistletoe infestation and negative health outcomes for parasitized trees. Western oak mistletoe was observed in 227 non-native trees, with most being oaks, suggesting it may be a benefit to wildlife.
A new perspective highlights emerging household contaminants that may increase the risk of heart disease, cancer, and developmental problems. The authors emphasize the need for systematic monitoring and research to inform next-generation indoor air standards.
A new study from the University of Oklahoma suggests that small genetic differences in two proteins may influence how their eyes develop, affecting the risk of retinopathy of prematurity (ROP). Researchers found four genetic variants specific to eye disease, with two protective and two increasing the risk. Early genetic testing could h...
A novel approach to chronic pain management uses induced pluripotent stem cell-derived peripheral pain-sensing neurons to treat osteoarthritis joint pain. The therapy, SN101, sequesters inflammatory pain factors without transmitting pain signals, preserving joint tissues and relieving chronic pain.
Maher El-Kady's work on sustainable energy storage technologies aims to create a cleaner, more accessible future. Dr. Dennis Slamon's breakthroughs in breast cancer treatment have benefited millions worldwide, highlighting the impact of UCLA researchers on global health and innovation.
Researchers at UCI will conduct a first-in-humans safety and tolerability study of an embryonic stem cell-derived neural stem cell product for Huntington’s disease. The clinical trial aims to protect brain cells, repair damaged brain circuits, and slow or prevent disease progression.
Researchers at the University of Plymouth investigate why drugs used to treat other tumours are ineffective against NF2-related schwannoma and meningioma tumours. They explore repurposing clinically tested cancer drugs to target MDR mechanisms, which may lead to effective therapies for patients with these tumours.