Researchers at Fox Chase Cancer Center found that fragmented care does not negatively impact survival outcomes for retroperitoneal sarcoma patients. Despite longer travel distances and delays between diagnosis and treatment, patients receiving nonfragmented care had equivalent overall survival rates as those with non-fragmented care.
Researchers found that lecanemab treatment resulted in rare and manageable side effects, especially in patients with very mild or mild Alzheimer's symptoms. Only 1% of patients experienced severe side effects requiring hospitalization, highlighting the feasibility and safety of the drug in real-world settings.
New research from Binghamton University reveals that the topography patterns of wrinkled fingers remain constant after multiple immersions. The study found that blood vessels beneath the skin contract and move in relation to other vessels, resulting in consistent wrinkles.
Researchers at SLEGS have made high-precision measurements of the 27Al(γ,n) cross section, resolving existing data discrepancies and providing more accurate nuclear reaction models. The study's innovative detector design and laser Compton scattering beams enabled direct comparisons with global datasets.
A new sunlight-powered system mimics plants to separate carbon dioxide from industrial sources, reducing energy consumption and emissions. The process uses sunlight to make a stable enol molecule reactive enough to 'grab' the carbon, with potential applications in air carbon capture.
Non-variceal extrahepatic portosystemic shunts (NVEPS) are abnormal vascular connections formed via neoangiogenesis due to sustained portal hypertension. They contribute to the development of portosystemic shunt syndrome, marked by progressive hepatic dysfunction and worsening Child-Pugh scores.
A new study found that providing hearing aids and advice on their use can help preserve social connections in older adults, reducing loneliness. The study showed that those treated for hearing loss retained one additional social connection over a three-year period compared to those who received no treatment.
Researchers found distinct monthly dynamics in primary spontaneous pneumothorax incidence by age group, with BMI and monocyte-lymphocyte ratio as key risk factors for recurrence. The study highlights the importance of investigating PSP epidemiology and risk factors.
HER3 plays a major contributor role to the survival and spread of various solid tumors, including breast, lung, colorectal, pancreatic, and gynecologic cancers. HER3 functions through interaction with other ErbB receptors, forming potent signaling pairs that drive cell survival, proliferation, and metastasis.
A study has found that AI tools are contributing to a surge in low-quality research papers using large health datasets. Researchers recommend stronger peer review processes, statistical reviewers, and transparent data usage to protect scientific integrity.
The USTC team identified a novel material design that enables record-breaking device performance in pure-red PeLEDs. They introduced a 3D intragrain heterostructure to enhance carrier confinement capacity, suppressing hole leakage and achieving unprecedented efficiency and brightness.
Sandia National Laboratories has achieved over $439 million in savings for the Department of Energy by streamlining purchasing agreements and securing volume pricing. The Supply Chain Management Center, created in 2006, facilitates collaboration between prime contractors to reduce costs and improve efficiency.
A decade-long study of snowsport instructors reveals that pursuing a career in a field you enjoy can be taxing, requiring financial, mental, and physical sacrifices. However, the research also found that participants reported experiencing significant personal growth and fulfillment.
A new study published at the European Congress on Obesity suggests that GLP-1 agonist drugs can lead to a clinically relevant change in BMI for children with severe obesity. In this study, 30% of children who received GLP-1 drugs experienced a significant reduction in BMI, compared to around 27% of those who did not receive them.
Researchers at Baylor College of Medicine used a sequencing-based approach to detect measles virus in Houston wastewater samples collected in early January 2025, two weeks before any reported cases. The method's high sensitivity and specificity suggest it can inform public health preparedness for potential outbreaks.
A study published in Journal of Clinical Investigation found that the loss of SOX9 gene contributes to greater tumor invasion and poorer outcomes in mice. The team discovered that combined inactivation of SOX9 and APC results in more invasive tumors, highlighting the potential for targeting both genes as a future treatment strategy.
Researchers developed a comprehensive cell line atlas to better understand the biology of advanced biliary tract cancer. The atlas identifies new molecular subtypes and therapeutic targets, offering a path toward more tailored treatment strategies.
A team of Chinese researchers found that chlorinated volatile organic compounds on mineral dust particles can be converted into highly toxic polychlorinated dibenzo-p-dioxins and dibenzofurans by sunlight. The study highlights the need to reassess the toxicity of commercial chemicals and their atmospheric conversions.
Researchers at Umeå University discovered that men have higher levels of inflammatory cytokine IL-18 and neutrophil activation markers compared to women, leading to increased risk of severe COVID-19
Researchers have discovered that flamingos employ a range of active feeding strategies, including stomping, head jerking and beak chattering, to concentrate brine shrimp and small animals into their mouths. These behaviors create whirlpools and eddies that funnel prey towards the birds' mouths.
Three Chinese, Indian, and South Korean researchers were awarded for their high-quality research on heart disease prevention and management. The American College of Cardiology recognized the contributions to advancing global heart health and patient outcomes.
Researchers create CARL-Bot to ride vortex rings and navigate turbulent ocean currents without fighting them, inspired by nature's ability to conserve energy. The system uses a single accelerometer and simple control laws to achieve energy-efficient propulsion, opening doors for future applications in ocean exploration and monitoring.
The Mount Sinai team's NYC-Vita trial combines lifestyle and pharmaceutical interventions to rebalance the immune system and restore health in older adults. The ambitious effort aims to develop practical, science-driven interventions that extend life and restore energy, focus, and strength.
A new study assesses the tradeoffs between clean air and clean water, finding that boiling contaminated water generally outweighs health risks from air pollution. The research supports prioritizing household access to clean water, especially for young children.
The new Epigraph vaccine developed by University of Nebraska-Lincoln virologist Eric Weaver protects against H1N1 swine flu and can also protect against influenza in humans and birds. The vaccine significantly outperformed commercial vaccines, providing protection for up to a decade.
The new system uses radar and reflective surfaces to monitor driver movements and determine their state of alertness. It has the advantage of being simple and cost-effective compared to conventional camera-based systems.
This observational study found that bronchoscopic lung volume reduction with endobronchial valves under moderate sedation has a lower rate of complications, particularly pneumothorax, compared to general anesthesia. The procedure can be safely performed with similar efficacy as demonstrated in previous studies.
Researchers investigated the effectiveness of CCS-MVR in treating functional mitral regurgitation and degenerative mitral valve disease. The study found that this procedure can reduce left ventricle volumes while sparing the apparatus, suggesting its potential as a long-term treatment option.
A collaborative research project led by Johannes Gutenberg University Mainz aims to understand the impact of thermally induced fracture formation on mineral rock properties. The study will help reduce associated risks and improve geothermal energy's efficiency.
A narrative review found disruptions in the cortico-striatal-thalamo-cortical pathway and dysregulation of dopamine and GABA primary neurotransmitters in patients with obsessive-compulsive spectrum disorders, chronic tic disorders, and attention-deficit/hyperactivity disorder. This may lead to more effective treatments for sleep-relate...
Researchers identified platelets, C-reactive protein, and chromogranin A as markers that can predict the failure of hormone-sensitive prostate cancer treatment. The study also found that miR-375 expression and lymphocyte-to-monocyte ratio are negative predictors for therapy failure in castration-resistant prostate cancer patients.
Research by MIT neuroscientists reveals that the brain separates its processing of spatial information to maintain cognitive advantage, yet seamlessly blends it with other features. The study also explores how the brain 'hands off' visual information between hemispheres.
Patients in an online obesity clinic achieved average weight loss of 16.7% after 64 weeks, similar to clinical trials of semaglutide, but using less than half the medication. The study found that personalized doses of semaglutide combined with behavioral therapy and support led to successful weight loss.
The Exeter Climate Forum will bring together world-leading researchers and policymakers to address the urgent need for climate action. The event aims to share the latest climate science and inspire bold ideas for solutions.
A new Stanford Medicine-led study reveals that CAR-T cell therapy causes mild cognitive impairments in cancer patients, independent of other treatments. Researchers identified the cellular mechanism behind this effect and found strategies to reverse it.
Researchers have discovered a selfish X chromosome in fruit flies that manipulates inheritance in both males' sperm and females' eggs. The supergene's unique structure allows it to expand and accumulate repetitive DNA sequences contributing to its ability to cheat during female reproduction.
Researchers from The University of Osaka developed a new technique using mass photometry to detect and quantify components of rAAV particles. This method can distinguish between full and empty particles, streamlining gene therapy manufacturing and improving clinical effectiveness.
Rice University's Matteo Pasquali has been elected a fellow of The Society of Rheology for his pioneering research contributions and exceptional leadership in the field. He is recognized for developing new carbon materials and scalable manufacturing methods.
The single-celled parasite Entamoeba histolytica infects 50 million people each year and can kill nearly 70,000. Researchers have discovered that it damages tissue through a process called trogocytosis, where it takes bites out of human cells and ingests their fragments to evade the immune system.
Researchers have developed a new compound, SHP1705, that selectively attacks glioblastoma stem cells by hijacked circadian clock proteins. The compound was found to be safe and well-tolerated in humans during a phase 1 clinical trial.
A Simon Fraser University study found that organizations can encourage disclosure of mental health concerns by creating a supportive work environment. Employees are more likely to disclose when they feel their organization is supportive and they will benefit from accessing resources.
The book analyzes the co-creation process of doctors, patients, and platforms to create value within digital health platforms. It provides practical solutions to improve platform operation and offers a framework for understanding internet health platform function and value creation.
The University of Texas at Arlington's nursing and physics team has developed a system to study alpha radiation, improving the effectiveness of radiation therapy. The team's research was recognized with the Best in Physics award at the American Association of Physicists in Medicine's annual meeting.
Researchers developed a large-scale indoor typhoon simulation tank to measure momentum, heat, and CO2 transfer at the air-sea interface. Their findings revealed key correlations between wind speed, wave morphology, and transport phenomena under extreme conditions.
Mitochondrial DNA editing has emerged as a revolutionary approach in the fight against neurodegenerative diseases. The dysfunction of mitochondria, triggered by mutations in mtDNA, is recognized as a pivotal factor contributing to conditions like Parkinson's disease, Alzheimer's disease, and Huntington's disease.
The study found that 18F-FAPI-04 PET/CT had higher maximum standardized uptake value and tumor-to-background ratio compared to 18F-FDG PET/CT for stage IA lung adenocarcinoma. This suggests that 18F-FAPI-04 PET/CT may be more effective in detecting stage IA lung adenocarcinoma lesions.
Researchers found that current drinkers who consumed 14 or more drinks per week had a 25% higher risk of colorectal cancer compared to those who drank less than one drink per week. The study also presented data on a novel immunotherapy treatment for acute myeloid leukemia, showing greater success and fewer side effects.
A new study has identified three social risk clusters associated with a higher risk of suicide in the US, highlighting the importance of broader community-level social conditions. The findings suggest that region-specific interventions addressing poverty, housing, and environmental stressors can help lower suicide rates.
A retrospective analysis from the National Center for Respiratory Medicine found that off-pump coronary artery bypass grafting combined with pulmonary resection is safe during the perioperative period, reducing postoperative complications and hospitalization costs. This treatment method provides a new option for lung cancer patients wi...
The Buck Institute's hybrid intervention combines a daily ketone ester with ICOPE-INTENSE, a personalized approach improving Intrinsic Capacity and age-related functions. The team aims to restore muscle, cognition, and immune function by 10 years in one year or less.
Scientists are constructing novel three-dimensional (3D) carbon crystals with superhard, conducting, and porous properties through 'Lego'-style assembly of carbon units. Experimental breakthroughs have enabled the synthesis of various 3D carbon structures using different techniques.
Engineers at RMIT University have invented a neuromorphic device that detects hand movement, stores memories, and processes information like a human brain without an external computer. The device uses molybdenum disulfide to capture light and process visual information instantly, enabling real-time decisions.
Children with autism who engage in whole-body movement show improved executive functioning and cognitive performance compared to those who participate in sedentary play. The study, led by University of Delaware professor Anjana Bhat, found that exercise increases blood supply to the prefrontal cortex and enhances attention span and lea...
A large-scale study published in eClinicalMedicine found that transmasculine and gender-diverse individuals who use testosterone for an average of five years do not have an increased risk of gynecological cancer. The research, which followed 1955 participants, suggests that hormone therapy may be safe for this group.
Researchers analyzed personal names from archaeological findings to detect patterns of identity, openness, and change in ancient Hebrew societies. They found that the Kingdom of Israel had a more diverse naming landscape than Judah, indicating a more open and cosmopolitan society.
Researchers at POSTECH have developed an interlocked electrode-electrolyte system that forms covalent chemical bonds between the electrode and electrolyte, maintaining long-term stability. The IEE-based pouch cell demonstrated significantly higher energy density compared to traditional lithium-ion batteries.
Research from the University of Adelaide reveals significant changes in echidna pseudo-pouch microbial communities during lactation, suggesting a unique environment that accommodates young with an immature immune system. The study's findings may inform breeding programs and conservation efforts for these egg-laying mammals.
Researchers have discovered that urban areas experience a greater difference in wet bulb globe temperature between 0.5 m and 1.5 m above ground due to surface heat radiation, posing health risks to children and pets during extreme heat events. Total solar eclipses also alter atmospheric conditions and insect behavior, with some species...
Researchers propose in-situ thermoelectric conversion on Mars, utilizing the abundant atmospheric gases for electricity generation and oxygen production. The technology shows promising environmental suitability and potential for significant weight reduction, enabling more efficient microreactors.
City of Hope's largest outpatient facility, Hope Plaza, brings together cancer experts for highly individualized care. The center offers cutting-edge technologies, over 735 clinical trials, and integrated supportive services.