Middle-aged adults with lower socioeconomic status exhibit less organized functional brain networks and reduced cortical gray matter thickness compared to those with higher SES. The study suggests that SES influences brain anatomy and network organization across adulthood, playing a role in age-related brain decline.
A CAMH study analyzed over 1,000 brain scans to provide new insights into brain networks in people with autism. The personalized brain mapping approach showed that each person's brain has unique differences in network functioning despite sharing the same diagnosis.
Researchers used mathematical models to re-enact brain development in humans, monkeys, and mice, finding that the human brain requires fewer initial cells to grow. The study suggests that humans may have adopted a different developmental program to produce neurons efficiently within a longer gestational period.
Researchers at the University of Calgary have shed new light on the identity of brain stem cells that exhibit neural stem cell function. The study found that ependymal cells do not become neural stem cells when activated by injury, but rather regulate their function.
The £18 million Brain Tumour Awards aim to advance understanding of brain tumours and develop new treatments. The awards focus on six major themes, including unlocking insights into brain tumour biology, developing more accurate diagnostic methods, and improving treatment approaches for patients.
A new computer programme assesses whole brain deterioration and predicts cognitive function after stroke up to ten times more accurately than current methods. The 'brain health index' can quantify visible brain injury from cerebral small vessel disease and brain atrophy, giving early warning of risk of future cognitive decline.
A recent study found that stereotactic radiosurgery (SRS) can improve overall survival and reduce cognitive side-effects in patients with brain metastases from small-cell lung cancer. The study compared outcomes of 5,752 patients who received whole-brain radiation therapy (WBRT) to those of 200 patients who received SRS.
A new study led by University of Arizona cognitive scientist Aneta Kielar found that people with primary progressive aphasia, a rare dementia, can recruit intact areas of the brain to decipher sentences. This brain compensation offers hope for developing targeted treatments for PPA.
Researchers discovered that patients with Primary Progressive Aphasia use different brain regions to process language, compensating for damaged areas. This finding holds hope for targeted treatments and earlier disease assessments.
A study by University of Sheffield researchers found that honeybee colonies follow the same laws as the human brain when making collective decisions, including Pieron's Law, Hick's Law, and Weber's Law. This discovery could lead to a better understanding of the basic mechanisms of human behavior and cognition.
Theresa Currier Thomas has received a $1.65 million grant to study traumatic brain injury and develop more effective treatments. The research aims to understand how communication in the brain changes after an injury, with implications for cognition, sensory processing, and mental health.
New findings from fetal brain scans reveal that mothers' stress during pregnancy changes neural connectivity in their developing child's brain. The cerebellum plays a key role in this effect, which may be linked to future human health and development.
Researchers propose a new concept to uncover connections between brain regions and cognitive functions, using a bottom-up approach. Recent advances in statistical methodology and brain imaging data provide the basis for this new method, which could help reveal the core functions of brain areas.
Research elucidates the neural basis of complex altruistic behavior, discovering two brain circuits that govern moral decisions in war veterans. The study used CT scans and an altruistic decision task to map brain damage and behavior, finding correlations between specific brain areas and punishment or donation behaviors.
Researchers at UCalgary have developed a portable brain imaging system that uses light to detect and monitor damage in the brain from concussion. The device measures communication in the brain by measuring oxygen levels, revealing patterns of blood flow and oxygen levels that change after concussion.
Researchers have identified over 250 genes involved in brain aging, including Dbx2, which can prematurely age stem cells. The study found that increasing the activity of Dbx2 in young brain stem cells slows their growth, causing them to behave more like older cells.
Researchers at the University of Arizona have discovered that brain liquefaction after a stroke can be toxic, slowly leaking into the remaining healthy portion of the brain and potentially causing harm. The study suggests that this toxic fluid may contribute to dementia after stroke.
Researchers created a detailed molecular atlas of brain blood vessels and the life-essential blood-brain barrier, providing new knowledge on cell functions and disease involvement.
Scientists from NUS and international research team create a novel method for deep brain stimulation, utilizing upconversion nanoparticles to deliver visible light deep into the brain. The innovation enables researchers to uncover valuable insights about brain functions with less invasive methods.
Scientists have found that a naturally occurring virus called reovirus can act as an effective immunotherapy in patients with brain cancer or other cancers that have spread to the brain. The virus replicates and kills cancer cells, while also stimulating the body's own immune system.
Pericytes, a type of cell on brain blood vessels, grow to cover empty space left by neighboring cells. This brain plasticity may help fight age-related vascular disorders like Alzheimer's disease and stroke.
Research finds brain lesions associated with increased risk of criminal behavior, specifically impacting the moral decision-making network. The study analyzed MRI and CT scans of individuals with brain lesions, revealing a strong correlation between lesions in the same brain network as those with criminal behavior.
Research at Kanazawa University identifies FGF signaling as essential for gyri formation in the cerebral cortex, enabling large-scale neuron development and brain functions. The study uses a ferret model to analyze genome-level interactions, revealing the importance of FGF signaling in gyrus formation.
A new study shows that very low levels of electrical stimulation can instruct an appropriate response or action in the brain, bypassing damaged senses. The findings have significant implications for the development of neuro-prosthetics and brain-computer interfaces.
A new study provides insight into the CLOCK gene's vital role in regulating human-specific genes important to brain evolution. The findings suggest that CLOCK regulates genes linked to cognitive disorders and has an important role in human neuronal migration, a process crucial for brain development.
Researchers at Stellenbosch University found that HIV affects the brain in early stages of infection, leading to decreased blood flow and brain functional impairment. The study used fMRI scans to compare brain activity of people with and without HIV, revealing a link between frontal lobe atrophy and cognitive symptoms.
ALS research reveals over-connected brain regions, reduced activity in specific areas as networks disintegrate. This breakthrough technology links dynamic EEG changes with anatomical changes captured by MRI scans.
Researchers construct whole-brain map of electrical connectivity in the brain, finding that low-frequency rhythms drive communication between frontal, temporal and medial temporal lobes. This work elucidates brain network communication during memory formation and supports efforts to enhance memory using brain stimulation.
The Cure Brain Cancer Foundation has awarded a $345,000 fellowship to Dr Ryan Cross to develop cancer-fighting immune T cells for brain cancer treatment. The research aims to improve patient survival rates and develop personalised treatments for children and adults with brain cancer.
A study published in Stem Cell Reports reveals that DNA-encoded factors influence the vulnerability of brain cells to Alzheimer's disease. Brain regions with higher Aβ protein levels are more susceptible to damage, while protected areas have a less toxic response.
Researchers at Brigham and Women's Hospital have developed a system to temporarily loosen the blood-brain barrier using microbubbles, allowing for real-time monitoring and controlled delivery of drugs to the brain. The approach offers improved safety and efficacy control for human clinical trials underway in Canada.
Researchers at Numenta propose a new theory for how the brain learns models of objects through movement, pairing sensory input with location signals. The theory predicts that even the first levels of processing in the brain are learning and recognizing complete objects.
Researchers suggest brain expansion and renormalization occur during skill acquisition, with brain volume increasing initially before returning to normal.
New brain stimulation techniques offer safer, targeted means to study brain function, improve memory, and treat neurological and psychiatric disorders. These advancements have the potential to reach areas deeper in the brain, deliver customized stimulation, and study diseases in new ways.
Research explores military-related brain disorders and potential treatments, including improved visual responses and neural stem cell therapy. Disruptions in brain networks may underlie symptoms of Gulf War Illness, such as changes in vision, language function, pain perception, and mood regulation.
Frequent alcohol consumption can lead to the death of stem cells responsible for creating new nerve cells in adult brains. Females are particularly susceptible to this damage, which may help develop new approaches to treating alcoholism.
Researchers found that gelatin accelerates the healing of the blood-brain barrier after acute brain injury by reducing microglial cell activation and promoting anti-inflammatory responses. This study has significant implications for the development of surgical treatments and brain implants.
A recent study published in Molecular and Cellular Biochemistry found that brain cells contain less polyunsaturated fatty acids compared to other major organs. This discovery, made by Dr. Junhwan Kim, PhD, has significant implications for understanding brain health and conditions like oxygen deprivation.
A recent study by Maastricht University Medical Center and Maastricht University found that a specific enzyme, NOX4, plays a crucial role in the brain's sensitivity to hypoxia. This discovery has significant implications for treating post-stroke brain damage.
Researchers developed software using machine learning to analyze EEG signals from preterm infants, providing an estimate of brain functional maturity. The method is more precise than current methods and enables automatic monitoring of premature infant brain development.
Researchers will count and catalog cell types in mouse brain using single-cell transcriptomics, aiming to build a comprehensive atlas of cell types that can be applied to the human brain.
Researchers will systematically identify and catalog cell types across the mammalian brain using molecular signatures and genetic targeting. The project aims to better understand brain function and dysfunction, with potential applications for therapeutic uses in humans.
The NIH BRAIN Initiative is expanding its efforts to develop new tools and technologies to understand neural circuit function and capture a dynamic view of the brain in action. Researchers are making rapid progress in visualizing the brain in action, identifying thousands of brain cells at a time, and developing innovative brain scanners.
Researchers developed improved mini brain organoids from stem cells, closely mimicking human brain structure. They found critical similarities between the organoids and real brain tissue and identified effective drugs to block Zika's entry into the brain, offering new avenues for studying neurological disorders
The NEMONIC project aims to develop and widely share new optical brain-imaging techniques, enabling the recording of brain cells in action. The team, led by UCSB scientists, uses light to measure brain activity, overcoming technological bottlenecks to understanding the mind and brain.
Scientists have developed a 3D all-human reproducible and reliable model of the blood brain barrier, which could pave the way for better, more efficient and reliable tests of drugs to treat brain diseases. The model was created using human cells to simulate the human blood-brain barrier.
Research suggests that traumatic brain injuries in childhood and adolescence can increase the risk of alcohol abuse problems in adulthood. The study found a clearer link between brain injury and alcohol abuse in people who suffered an injury before age 5, with children under 5 being over 3.6 times more likely to exhibit substance abuse...
Researchers at McMaster University have discovered two new genes, SPOCK1 and TWIST2, that regulate brain metastases in lung cancer patients. These genes are present in the primary lung cancer of all patients with brain metastases but not in those without them.
The UCSB Brain Initiative, a cross-disciplinary program tackling the mind and brain, has received a significant boost from the Hearst Foundation. The award will support the initiative's efforts to transform our understanding of the human brain and provide new tools for neuroengineering.
Researchers developed FAST - a fast whole-brain imaging system that can visualize individual cells and subcellular structures in the entire brain. This technique allows for faster comparison of multiple brains to gain new insights into brain diseases.
Researchers found significant dose-dependent changes in cortical neural networks after radiotherapy for brain tumors, affecting global network effects and cognitive processing.
Researchers use tiny bubbles and ultrasound to safely open the blood-brain barrier, a heavily guarded system that prevents drug delivery. This breakthrough approach aims to advance next-generation brain therapies without surgery.
A study by neuroscientists at Duke and Stanford University found that multiple brain regions collaborate to produce empathetic decision-making in rats. The results clarify conflicting findings on the role of specific brain regions in guiding antisocial behavior, suggesting a more complex neural context.
A new brain network model suggests that understanding brain connections and structure can help predict how brain function changes after injury. The study identified key white matter pathways and lesions responsible for network disruptions, which could lead to more accurate treatment plans and therapeutic targets.
Researchers led by SDSU neuroscientist Stephanie Ries discovered that wide swaths of the brain work in parallel to retrieve correct words from memory, challenging previous assumptions about localized language processing. The study's findings could help speech-language pathologists develop strategies for treating disorders like anomia.
A new study from Newcastle University shows that the exact time of neuron development and its position in the brain are key to forming neural connections. This understanding can lead to better diagnosis and treatment of developmental diseases like schizophrenia, autism, and ADHD.
Researchers found that radiation therapy can alter neural networks and lead to cognitive decline in patients with brain tumors. The study suggests that the treatment may cause broader adverse effects, including thinning of the brain cortex and increased segregation between brain regions.
Researchers at Brigham and Women's Hospital have developed a new model to mimic the blood-brain barrier, using miniature spheroids that replicate key properties and functions. This innovative approach may advance neuroscience research and expedite the discovery of brain-penetrant drugs for treating diseases.
MIT researchers create temporally interfering (TI) stimulation, a new technique that stimulates neurons in the brain without implants. This method uses low-frequency electrical signals to target specific areas of the brain, offering new possibilities for brain research and potential treatments for conditions like Parkinson's disease.
Researchers have developed a noninvasive method for deep brain stimulation using electrodes placed on the scalp, which could make the treatment less risky, less expensive, and more accessible. The approach has shown promising results in treating Parkinson's disease and other conditions, with no harmful effects detected.