Articles tagged with Disease Control
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
A new rapid test for hepatitis C could identify more patients who can be cured if insurers increase reimbursement to cover the test's high cost. The test's point-of-care feature makes it ideal for early screening and treatment in clinics and emergency rooms.
A new modeling study suggests that regular testing for sexually transmitted infections (STIs) can successfully reduce their spread, even if individuals on PrEP engage in riskier behavior. The paradoxical findings highlight the importance of careful surveillance data interpretation when evaluating public health interventions.
A comprehensive review of 19 multi-day events found that nearly 70% of reported emergencies were infectious disease outbreaks, with influenza, measles, and meningococcal disease being the top causes. Foodborne illnesses accounted for over one in five incidents, often linked to poor food handling practices.
Researchers have created a model that can handle complex mosquito behavior and its impact on human diseases. The study reveals surprising findings, such as it may be better to let a mosquito bite you in terms of overall transmission.
Researchers find a fourteenth-century Arabic poem misinterpreted as factual account of plague's movement, influenced myths of its quick spread across Asia. The study highlights the importance of maqāmas in understanding how communities coped with catastrophic events like the Black Death.
A new study projects that US funding cuts will result in a catastrophic effect on pediatric TB, with children in Sub-Saharan Africa and Southeast Asia experiencing a significant spike in preventable cases and deaths over the next decade. The loss of US bilateral health aid is projected to result in an additional 2.5 million pediatric T...
Scientists analyzed thousands of proteins in blood samples to understand when multiple sclerosis attacks the myelin sheath and nerve fibers. Researchers identified a protein called IL-3, which plays a key role in this early phase of damage.
Climate change is allowing disease-carrying insects to spread into new areas, resulting in a growing number of West Nile virus infection cases in Europe. The virus can attack the nervous system and brain, causing symptoms like fever, headache, and malaise, with severe consequences for vulnerable individuals.
Research links oral bacteria to Parkinson's disease via the gut-brain axis, finding Streptococcus mutans produces metabolite imidazole propionate that contributes to disease progression. Targeting the oral-gut microbiome may offer a new therapeutic approach for Parkinson's treatment.
Researchers have created a statistical model using 20 years' worth of sentinel chicken data to predict elevated West Nile virus activity up to six months in advance. This breakthrough could lead to proactive preventative measures and improve disease outbreak response.
Researchers synthesized hybrid vitamin K analogues with enhanced neuroactive properties, exhibiting threefold greater potency in inducing neural progenitor cell differentiation compared to natural vitamin K. The compounds preserved vitamin K and retinoic acid's biological activity via the SXR and RAR receptors.
Researchers developed standardized guidelines to diagnose and treat cemental tears, reducing misdiagnosis and improving patient outcomes. The consensus identifies key risk factors, diagnostic strategies, and treatment principles, empowering clinicians to recognize and manage this hidden threat more effectively.
Researchers developed wearable microneedle patches that improve drug absorption while reducing pain in long-term delivery. The new technology, inspired by bee stings, enables continuous drug release and anchors securely into the skin.
Researchers at Penn State have identified certain characteristics that can help predict whether a virus will persist in a new population. Infection prevalence and viral shedding were found to be significant predictors of long-term viral persistence. The study used a worm model system to examine disease transmission and emergence at a p...
The new book explores organoid bioengineering, using pluripotent and adult stem cells to create models for various organs. It discusses breakthroughs in personalized cancer care and large-scale production protocols supported by advanced tools like 3D printing and genome editing.
This study uses an analytical model to examine the effects of influenza vaccination on both vaccinated and unvaccinated populations. The results show that vaccination provides significant reductions in disease burden, even when vaccine effectiveness is low, but these benefits are limited in high transmission situations.
Researchers at Heidelberg University developed high-resolution environmental suitability maps to identify areas conducive to breeding, leveraging satellite imagery and climate data. The maps help guide targeted interventions in mosquito-endemic urban areas.
Researchers have discovered that a bacterial probiotic helps slow the spread of stony coral tissue loss disease (SCTLD) in already infected wild corals in Florida. Applying the probiotic treatment across entire coral colonies helped prevent tissue loss, providing a more lasting protection than traditional antibiotics.
Cessation of public water fluoridation would lead to higher rates of tooth decay and increased healthcare costs in the US. The model suggests that current safe levels of fluoride have substantial ongoing benefits.
This novel treatment approach yields better weight loss maintenance and cardiovascular risk outcomes compared to standard-of-care treatment. Patient-delivered lifestyle intervention combined with peer support significantly improves weight loss and reduces cardiovascular risk.
AIC100 demonstrated encouraging responses and an acceptable safety profile in patients with two types of advanced thyroid cancer, including anaplastic thyroid cancer (ATC) and relapsed/refractory poorly differentiated thyroid cancer (PTDC). The therapy showed significant tumor shrinkage and disease control in 56% of patients.
Researchers developed promising α-synuclein PET tracers that can visualize protein aggregates in living patients, enabling earlier diagnosis and treatment monitoring. Tracers like [18F]C05-05 and [18F]ACI-12589 showed significant results in distinguishing synucleinopathies from healthy controls.
The European Centre for Disease Prevention and Control (ECDC) emphasizes the need for high immunization coverage to protect European populations from diseases like measles and polio. Vaccination remains a crucial tool in public health, with recent data showing a tenfold surge in reported measles cases in the EU/EEA.
Researchers at MIT developed a control circuit that can precisely regulate gene expression levels, improving the efficacy and safety of gene therapy treatments. The 'COMMAND' circuit uses microRNA to suppress gene expression, allowing for tighter control over treatment outcomes.
A hospital-based outbreak detection system has been shown to prevent infections, save lives and cut costs. The Enhanced Detection System for Healthcare-Associated Transmission (EDS-HAT) uses genomic sequencing to analyze infectious disease samples from patients, identifying near-identical strains that flag potential outbreaks.
Researchers discovered that CsrA gathers in droplet-like structures inside cells to control bacterial gene activation. These compartments help bacteria adapt to environments and switch between harmless and virulent states.
Researchers at UMass Amherst's New England Center of Excellence in Vector-borne Diseases have identified a new strain of Rickettsia bacteria that causes spotted fever infections in humans. The discovery in Maine suggests rabbit ticks could be a zoonotic vector for serious infections, contradicting the usual dog tick vector.
Researchers identified a potential new treatment, lorundrostat, which reduced systolic blood pressure in individuals with uncontrolled or treatment-resistant hypertension. The study found a significant 15-point reduction in systolic blood pressure compared to placebo.
A new strategy for tuberculosis (TB) screening could significantly improve detection, allowing for simultaneous screening of both active and dormant infections. This approach has the potential to save lives, curb infection rates, and rewrite the story of TB's continued spread.
A mysterious parasite is devastating fish farms globally, causing £50 million in losses annually. Researchers have discovered a new gene regulation process that could lead to the development of gene-based vaccines.
A multi-state study found that only half of high-risk adults with flu received antiviral treatment, highlighting a critical need for timely care. The gap in treatment increases the risk of severe flu complications, particularly among older adults and those with underlying conditions.
A mathematical modeling study suggests that sustained HIV remission or eradication could consistently reduce new HIV infections among men who have sex with men (MSM) in the Netherlands. However, transient remission with a risk of rebound may increase new infections if not closely monitored.
New research found that COVID vaccines significantly reduced the risk of long COVID in children and adolescents. Vaccination was about 95% effective in preventing long COVID in some cohorts, primarily due to its ability to prevent initial infection.
A new study models cholera transmission after interventions in the Democratic Republic of the Congo, highlighting the importance of environmental reservoirs in maintaining endemic diseases. The research suggests that vaccination may have a smaller impact on preventing transmission compared to water, sanitation, and hygiene improvements.
A subset of patients with non-small cell lung cancer who discontinued immune checkpoint inhibitor therapy due to immune-related adverse events continued to experience long-term disease control. The median post-discontinuation progression-free survival was 12.7 months, and the median post-discontinuation overall survival was 43.7 months.
A study of over 300,000 adults found that those with diabetes are 25% more likely to lose their health insurance. Insurance instability is particularly concerning for those with complex needs, as many struggle to regain coverage after losing Medicaid or private insurance.
Cervical cancer cases worldwide reached 622,301 in 2022, with significant variations in age-standardized incidence rates across regions. Targeted prevention programs, especially HPV vaccination in low-income countries, are essential to reduce the global health burden.
Researchers highlight the potential of AI in diagnosing and treating myopia, detecting risk factors and predicting outcomes. However, challenges such as data quality and patient privacy must be addressed to improve widespread clinical application.
Recent cases of multi-drug resistant cholera in the UK and Germany are linked to exposure to contaminated holy water from Ethiopia. The study found a connection between pilgrims consuming or bathing in the holy well and the spread of the disease.
A new study reveals that the US national vaccine strategy saved more money than it spent on testing, buying and delivering COVID-19 vaccines after just one year. The analysis found that the vaccines reduced serious illness and deaths, resulting in significant cost savings.
A recent study found that ischemic stroke mortality rates have increased in the US over the past two decades, particularly among racial minorities and rural residents. The majority of these deaths now occur at home, rather than in hospitals or medical facilities.
A project aims to understand how temperature, light pollution, and bird abundance affect West Nile virus transmission in mosquitoes. The goal is to advise health departments on the best time to kill bugs and limit transmission.
The American Heart Association invites communities nationwide to walk together on National Walking Day to break the cycle of sedentary behavior. Regular walking can improve both physical and mental well-being, even in small steps.
A new study found that reported tuberculosis diagnoses among incarcerated people in Europe and the Americas plummeted by up to 100% during the pandemic, despite consistent incarceration rates. This reduction was distinct from general population trends, highlighting the need for improved healthcare systems within prisons.
A UK study found that children of obese mothers are more likely to become obese adults, suggesting that societal and early-life factors play a significant role in obesity. The study analyzed data from over 17,000 people born in the same week in 1958 and found that these early life factors persisted through adulthood.
The rate of maternal mortality related to cardiovascular causes has more than doubled between 1999 and 2022 in the US. Researchers attribute the increase to factors such as socioeconomic disadvantages, limited access to healthcare, and higher prevalence of risk factors.
A study published in the International Journal of Manpower found that offering paid time off (PTO) significantly reduces the likelihood of employees quitting their jobs, with a greater reduction for men. PTO does not affect job satisfaction, which independently reduces turnover by 30-40%. Flexible scheduling also reduces turnover, but ...
Researchers discovered that exposure to similar behaviors within a person's social network is the most significant factor predicting individual prevention behaviors. Household-level interventions targeting entire families could result in more effective prevention strategies.
Genalive wins largest outsourced testing service contract in Saudi Arabia's history, covering 83 public hospitals and multiple genomics methodologies. The deal will enhance local precision medicine services with comprehensive solutions for whole genome sequencing, exome sequencing, and more.
A new Mass General Brigham study explores the connection between the Doomsday Clock and mortality and mental health in the United States, finding higher rates of Alzheimer's disease, suicide, and substance-related disorders at closer clock settings. The study suggests a potential bridge between global events and individual well-being.
The European Centre for Disease Prevention and Control reports a significant increase in measles cases across EU/EEA countries, with eight out of ten unvaccinated individuals contracting the disease. Vaccination levels fall short of the 95% target, leaving vulnerable populations susceptible to measles.
A new study by researchers at UCSF has found that long-acting injectable treatments can be transformative for patients who struggle to take daily HIV pills, resulting in undetectable viral loads and improved health outcomes. The treatment approach could help stop the spread of HIV by keeping more patients from being infectious.
Researchers have identified novel mosquito repellents with high success rates from natural sources, including food and flavoring materials. The team's machine learning-based cheminformatics approach also pinpointed pyrethroid analogs up to 100 times more effective than existing industry standards.
A survey reveals that most people are unaware of HPV's impact on cancer risk and its spread. The human papillomavirus (HPV) is more common among men than women, and the virus is associated with rising rates of oropharyngeal cancers, which can take years to develop after initial infection.
The study found that the prevalence of adults with diabetes did not significantly change between 2013 and 2023. However, glycemic control among those with diagnosed disease worsened, particularly among young adults. This trend is concerning due to its potential impact on lifetime risk of cardiovascular events.
A recent study from the University of Missouri and Yale University found that restricting flavored e-cigarettes leads to a decrease in vaping among young adults. However, this restriction also increases traditional cigarette smoking among young adults compared to states without such restrictions.
A long-term study in the Spiti valley of the Himalayas found that livestock grazing leads to reduced spider populations and increased grasshoppers and disease carriers like ticks and mites. The researchers suggest rewilding native herbivores and improved surveillance to mitigate these changes.
Researchers found that squat toilets release higher concentrations of bacteria than bidet toilets, but ventilation fans significantly lower these levels. Installing efficient exhaust fans can effectively reduce bioaerosol concentrations and exposure risks for the public.
A new study from the University of Texas at Arlington found that Americans aged 65 and older who experienced parental divorce as children were more likely to suffer a stroke compared to their peers. The study analyzed data from over 13,000 older Americans and found that about 14% had experienced parental divorce during childhood.
A team from Tokyo Metropolitan University has successfully implanted myoblasts onto healthy muscle in mice using an extracellular matrix scaffold. This breakthrough treatment could treat ageing-related muscular atrophy without scarring, offering a promising avenue for regenerative medicine.