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The clinical practice guideline update on adult sinusitis emphasizes patient education, shared decision-making, and evidence-based treatment options

The updated guideline emphasizes watchful waiting as the preferred approach for most bacterial sinus infections, while also providing clearer guidance on antibiotic use. The new recommendations aim to reduce unnecessary antibiotic prescriptions and promote effective symptomatic treatments.

Cannabis use and benign salivary gland neoplasms

A recent study published in JAMA Otolaryngology–Head & Neck Surgery found an association between cannabis use disorder and benign salivary gland tumors. The researchers call for further prospective research to confirm this association and understand the relationship between cannabis use and these tumors.

SourceJAMA Network·JournalJAMA Otolaryngology–Head & Neck Surgery·DateJul 17, 2025

Hearing devices significantly improve social lives of those with hearing loss

A study from the University of Southern California found that adults with hearing loss who used hearing aids or cochlear implants were more socially engaged and felt less isolated compared to those who didn't use them. The researchers also found that these devices can help reduce loneliness and improve social quality of life.

SourceUniversity of Southern California - Health Sciences·JournalJAMA Otolaryngology–Head & Neck Surgery·DateJul 3, 2025

Social outcomes among adults with hearing aids and cochlear implants

A systematic review and meta-analysis reveals that adults with hearing loss can enhance social engagement and functional outcomes by using hearing aids or cochlear implants. The study suggests that these devices should be encouraged for individuals with hearing loss to potentially improve their quality of life.

SourceJAMA Network·JournalJAMA Otolaryngology–Head & Neck Surgery·DateJul 3, 2025

New clinical practice guideline for the surgical management of chronic rhinosinusitis in adults

The new Clinical Practice Guideline offers proven, research-based treatment options for patients with chronic sinus problems. The guideline provides key action statements covering surgery and additional treatments to ensure patients receive excellent care before, during, and after surgery.

SourceAmerican Academy of Otolaryngology - Head and Neck Surgery·JournalOtolaryngology Head & Neck Surgery·DateMay 27, 2025

Vitamin D nasal spray treats loss of smell in mice

Researchers at the University of Florida have discovered a vitamin D nasal spray that significantly reduces nasal inflammation and improves sense of smell in mice. This study suggests a new potential treatment for humans suffering from loss of smell due to inflammation, which is often caused by cigarette smoke or COVID-19.

SourceUniversity of Florida·JournalInternational Forum of Allergy & Rhinology·TypeExperimental study·DateApr 8, 2025

Study finds tonsil removal not linked to undesirable weight gain, contrary to popular belief

Researchers found no correlation between adenotonsillectomies and undesirable weight gain in children with mild sleep-disordered breathing. The study used data from a clinical trial involving 458 children and showed that adenotonsillectomy improved symptoms, blood pressure, and quality of life but not primary neurodevelopmental outcomes.

SourceMichigan Medicine - University of Michigan·JournalJAMA Otolaryngology–Head & Neck Surgery·TypeRandomized controlled/clinical trial·DateDec 11, 2024

New study links air pollution with higher rates of head and neck cancer

A recent study published in Scientific Reports correlates higher levels of pollutant particulate matter with increased occurrences of head and neck aerodigestive cancer. The research found a significant association between exposure to PM2.5 and the incidence of head and neck cancer, shedding light on the environmental factor contributi...

SourceWayne State University - Office of the Vice President for Research·JournalScientific Reports·TypeData/statistical analysis·DateNov 12, 2024

New imaging technique to improve head and neck cancer surgery

Researchers developed a new imaging technique using fluorescence-guided surgery to enhance visibility of tumors and nerves during head and neck cancer surgery. The technique uses two near-infrared fluorophores, one for tumors and another for facial nerves, allowing for clear differentiation between cancerous tissues and nerves.

SourceSPIE--International Society for Optics and Photonics·JournalJournal of Biomedical Optics·DateNov 7, 2024

Throat problems could impair autonomic nervous system's ability to regulate blood pressure

Researchers found that patients with throat symptoms had reduced baroreflex sensitivity and higher resting heart rates compared to those without symptoms. The study suggests that throat problems can have a significant impact on autonomic nervous system function, potentially leading to long-term survival risks.

SourceUniversity of Southampton·JournalJAMA Otolaryngology–Head & Neck Surgery·DateSep 11, 2024

Cannabis use and head and neck cancer

A cohort study found an association between cannabis-related disorder and the development of head and neck cancer. The study highlights the need for further research on the mechanism of this association and dose response to support evidence of cannabis use as a risk factor.

SourceJAMA Network·JournalJAMA Otolaryngology–Head & Neck Surgery·DateAug 8, 2024

Lancet Oncology publication establishes imaging guidelines for head and neck cancers, a step toward practice change

The study establishes criteria for identifying extranodal extension on imaging, allowing radiologists to make accurate calls and provide patients with less invasive treatments. This shift towards practice change has the potential to reduce side effects and improve outcomes for patients with HPV-associated head and neck cancers.

SourceUniversity of Oklahoma·JournalThe Lancet Oncology·TypeSurvey·DateJul 16, 2024

Mayo Clinic marks medical milestone with world’s first known successful total larynx transplant performed in a patient with an active cancer as part of a clinical trial

Mayo Clinic's surgical team successfully performed the rare procedure, which included multiple organs, on a Massachusetts man with a rare form of laryngeal cancer. The landmark surgery, conducted as part of a clinical trial, marks a significant step towards making larynx transplantation available to a wider population.

SourceMayo Clinic·JournalMayo Clinic Proceedings·DateJul 9, 2024

Enhancing nasal endoscopy with AI

A new study uses convolutional neural networks to improve nasal endoscopy accuracy and efficiency. The model achieved impressive results, identifying the inferior turbinate and middle turbinate with an average accuracy of 91.5%, precision of 92.5%, and recall of 93.8%.

SourceOchsner Health System·JournalInternational Forum of Allergy & Rhinology·DateJun 28, 2024

ASTRO issues clinical guideline on radiation therapy for patients with HPV-related throat cancer

The American Society for Radiation Oncology (ASTRO) has published an updated clinical guideline for treating patients with HPV-related oropharyngeal squamous cell carcinoma. The guideline emphasizes the importance of tailored radiation strategies to maximize patient survival while minimizing side effects. It provides recommendations fo...

SourceAmerican Society for Radiation Oncology·JournalPractical Radiation Oncology·TypeSystematic review·DateJun 18, 2024

University of Cincinnati research examines chronic sinusitis

Researchers from the University of Cincinnati found that nearly half of patients with nasal allergies also have chronic rhinosinusitis (CRS), a condition often misdiagnosed as allergies. The study suggests that specific counseling and education are needed to raise awareness of CRS, especially in regions with high prevalence of environm...

SourceUniversity of Cincinnati·JournalOtolaryngology Head & Neck Surgery·TypeObservational study·DateFeb 26, 2024

Gene therapy restores hearing in children with hereditary deafness

A novel gene therapy has been shown to restore hearing function in six children with DFNB9, a form of autosomal recessive deafness. The treatment, which uses an adeno-associated virus carrying a version of the human OTOF gene, demonstrated significant improvements in speech perception and ability to conduct normal conversation.

SourceMass Eye and Ear·JournalThe Lancet·TypeExperimental study·DateJan 24, 2024

Certain per- and polyfluoroalkyl “forever chemicals” identified as potential risk factor for thyroid cancer

A recent study published in eBioMedicine found an association between certain per- and polyfluoroalkyl substances (PFAS) and an increased risk of thyroid cancer. The researchers investigated plasma PFAS levels in thyroid cancer patients and non-cancer controls, finding a significant positive association with exposure to n-PFOS.

The latest in science and medical advancement in otolaryngology-head and neck surgery to be presented at AAO-HNSF Annual Meeting

The AAO-HNSF 2023 Annual Meeting & OTO Experience will feature groundbreaking clinical research and professional development emerging within otolaryngology. The meeting will showcase the latest scientific oral presentations on various topics, including Otology, Laryngology, Endocrine Surgery, and more.

New Journal of Pharmaceutical Analysis articles showcase promising therapeutic candidates for treating cancer and hearing loss

Researchers developed innovative techniques to treat challenging cancers and manage therapy side effects. Inhibitors targeting PRMT5, a histone-modifying enzyme, alleviated cisplatin-induced hearing loss, while nano-pills delivered combination drugs to liver cancer cells.

SourceCactus Communications·JournalJournal of Pharmaceutical Analysis·TypeExperimental study·DateAug 8, 2023

Millions of patients do not have full recovery of smell or taste senses after COVID infection, study finds

A retrospective analysis of national data found that over 20 million Americans experienced loss of smell or taste after COVID infection, with a large portion never fully recovering these senses. The study estimated that almost 28 million Americans may be left with decreased sense of smell after COVID infection.

SourceMass Eye and Ear·JournalThe Laryngoscope·TypeMeta-analysis·DateJun 12, 2023

Genomic screening can help detect thyroid cancer, Geisinger study finds

A Geisinger study found that genomic screening can help detect medullary thyroid cancer (MTC) in patients with RET gene variants. The research evaluated 75 patients who had the genetic results, and 12 were found to have cancer after undergoing surgery. Genomic screening provides opportunities for early detection and treatment of MTC.

SourceGeisinger Health System·JournalJAMA Otolaryngology–Head & Neck Surgery·DateJan 25, 2023

Genetic diagnosis helps guide care of childhood hearing loss

A recent study found that genomic testing can identify genetic causes of childhood hearing loss and provide critical information on its clinical characteristics. The researchers detected variants responsible for hearing loss in 43 different genes, and the severity of hearing loss varied by gene.

SourceUniversity of Washington School of Medicine/UW Medicine·JournalJAMA Otolaryngology–Head & Neck Surgery·TypeObservational study·DateJan 18, 2023

BRIGHT outlook: A brief cognitive behavioral therapy appears promising for head and neck cancer survivors suffering from body-image distress

A new brief tele-cognitive behavioral therapy, BRIGHT, shows promise in reducing body-image distress among head and neck cancer survivors. The trial found that levels of body-image distress fell significantly for those who received the therapy compared to standard survivorship education.

SourceMedical University of South Carolina·JournalJAMA Otolaryngology–Head & Neck Surgery·DateJan 5, 2023