Articles tagged with Heart
A new device inspired by fish's lateral line senses the pulse of lab-grown heart tissue, enabling real-time monitoring of hundreds of tests. This breakthrough could revolutionize drug screening and personalized medicine with more accurate human tissue simulations.
Researchers have discovered a new way to detect sudden cardiac death risk using AI, which outperforms existing methods and can identify high-risk patients more accurately. The tool uses EKGs to analyze waveform patterns and has shown promise in predicting patient outcomes with a 7% annual rate of sudden cardiac death.
A new AI algorithm has been developed to screen for underlying heart failure in GP clinics or at home, aiming to reduce waiting times and save NHS costs. The test uses a routine Electrocardiogram recording to detect changes in the heart's structure and pumping functions.
Research synthesis reveals consistent biomarker increases and minor ventricular function changes after marathon running, varying by age, sex, and training level. However, the clinical relevance of these changes remains unclear, warranting further study to determine physiological responses versus long-term adaptations.
The American Heart Association warns that extreme heat events are increasing, posing significant cardiovascular risks. The statement outlines contributing factors and recommendations to mitigate these risks, particularly for vulnerable populations such as older adults and those with low incomes.
A new target for treating sleep apnea has been identified through a study in mice, showing that the farnesoid X receptor plays a central role in driving fatty plaque buildup during sleep apnea-like conditions. The study found that removing this receptor resulted in reduced fatty plaques and minimization of gut microbiome disruptions.
Researchers found biomarkers for Alzheimer's disease that correlated with minor cognitive differences in midlife adults. These biomarkers, measuring tau and amyloid plaque, were associated with a greater chance of cognitive decline, particularly in processing speed and executive function.
A new study found that a simple angiogram scoring system can identify patients whose heart muscle is still alive even when a major artery has been completely blocked. This breakthrough could change how cardiac patients are treated and help doctors make faster, more informed decisions.
A new study by the University of Ottawa suggests that a tiny molecule, methylglyoxal, plays a major role in triggering neurological disorders after a heart attack. The molecule accumulates in the brain following a heart attack and is linked to depression, anxiety, and cognitive decline.
Researchers identified a key protein called PERM1 that is restored in patients whose hearts recover after left ventricular assist device (LVAD) support. PERM1 regulates energy production and contractile function in heart cells, and its normalization is associated with improved cardiac function.
A new science advisory calls for coordinated international efforts to reduce disparities in care for children with Kawasaki disease, a rare but serious illness primarily affecting young children. The advisory highlights the importance of sharing data, expertise, and best practices to improve heart health outcomes for children with Kawa...
A Concordia-designed simulator models hemodynamics in reduced gravity environments, revealing key differences in blood flow and pressure patterns. The system successfully reproduced effective CPR on Earth and generated consistent blood flow under both normal and hypogravity conditions.
Researchers treated seven patients with advanced heart disease and difficult-to-treat ventricular tachycardia. The therapy resulted in a 79% reduction in VT episodes, with no serious treatment-related side effects during follow-up of up to two years. Proton beam therapy offers a new approach for patients with limited treatment options.
A University of Texas at Arlington researcher is leading a study investigating cardio-sarcopenia, the combined loss of heart and muscle health in aging adults. The grant aims to uncover how heart dysfunction and muscle loss interact and detect biomarkers for earlier intervention.
The Adams Valve Institute aims to expand the treatment of valvular heart disease, focusing on complex surgeries and underserved populations. The Institute will promote innovation in advanced imaging, reconstructive surgical techniques, and breakthrough research.
A simple ECG test can identify racehorses at risk of cardiac arrhythmias during high-intensity exercise. The test uses short ECG recordings taken at rest or light exercise to distinguish horses likely to develop premature beats.
A new trial found that using a microaxial flow pump before and during cardiac stenting procedures for high-risk heart attack patients with severe heart attacks did not reduce heart damage. The study, published in the Journal of the American College of Cardiology, also showed increased bleeding complications.
A new 4D digital heart model has been shown to improve patient outcomes in cardiac resynchronization therapy (CRT) for heart failure. The model, developed at the University of Calgary, enables personalized pacemaker placement, leading to a 10.8% increase in heart function compared to standard care.
A Korea University study reveals that liver metabolic disease is a key risk factor for heart failure in older adults with atrial fibrillation, with MASLD having the lowest risk and ALD carrying the highest risk. The study highlights the importance of liver health in cardiovascular disease management.
A new biotech company, Ibnova Therapeutics, will accelerate treatments for heart disease through cellular therapies, backed by Australian and Danish partnerships. The company aims to conduct human clinical trials within three to five years.
GLP-1 weight-loss drugs may prevent further tissue damage following a heart attack, significantly reducing the risk of further life-threatening complications. Researchers found that these drugs improve blood flow to the heart by activating potassium channels, relaxing constricted blood vessels and reducing heart damage risk.
Washington State University researchers identified a critical region in the leiomodin protein that regulates filament length, essential for maintaining a healthy heartbeat. The discovery may hold clues to future treatments of cardiomyopathies and other heart conditions.
A new study reveals that C-reactive protein is associated with ventricular arrhythmias in stable coronary disease, while its relationship with heart rhythms is different in patients with cirrhosis. In cirrhosis, only high white blood cell count shows a trend for linking to unstable rhythms.
A new study suggests that AI can help doctors detect serious heart valve disease years earlier, potentially saving thousands of lives. The AI algorithm correctly identified 98% of patients with severe aortic stenosis and 94% of those with severe mitral regurgitation.
Post-stroke spasticity affects an estimated 30-80% of stroke survivors, causing abnormal muscle tightness and involuntary spasms. Earlier diagnosis and timely intervention may improve functional outcomes and reduce long-term disability, according to the new scientific statement.
A recent study published in JAMA Internal Medicine found that oral semaglutide has a potential benefit in reducing heart failure events among people with type 2 diabetes and existing heart failure. The data support the use of oral semaglutide as a treatment option for these patients.
The FIU-Florida Heart Research Foundation Center for Innovation in Cardiovascular Health brings together experts in various fields to uncover the fundamental drivers of cardiovascular disease. The center will focus on AI-powered diagnostics, regenerative tissue technologies, and workforce development.
A recent study analyzed data from the Coronary Artery Risk Development in Young Adults (CARDIA) study and found that men developed coronary heart disease 10 years before women. The study indicates that this sex gap remains, with men having a higher cumulative incidence of cardiovascular disease and its subtypes.
A recent study from Penn State College of Medicine researchers found that helper T cells, typically involved in fighting infections, become overly activated in failing human hearts, causing damage. The activation of these T cells highlights the impact of inflammation and immune dysfunction in heart failure.
The PUMA trial will compare two invasive monitoring devices in open-heart surgery, with patient leaders guiding the research. The study aims to reduce unnecessary treatments, shorten ICU stays and cut healthcare costs.
Researchers have developed a new computational model that can analyze factors affecting the success of device installation and patient evolution. The model enables precise calculation of anticoagulant doses needed post-operation, reducing risk and improving safety for patients with atrial fibrillation.
A new study in Circulation: Population Health and Outcomes journal found that TV characters were more likely to receive CPR than real-life counterparts. This discrepancy highlights the need for accurate depictions of hands-only CPR on television.
Veteran male athletes over 50 are more likely to experience abnormal heart rhythms during training if they have scarring in their hearts. Exercise itself is not the cause, but can act as a trigger for dangerous heart rhythms in those with underlying heart issues.
Researchers at NIH and Emory School of Medicine have successfully performed a minimally invasive coronary artery bypass without cutting the chest wall. The new technique, called ventriculo-coronary transcatheter outward navigation and re-entry (VECTOR), creates a new route for blood flow that is safe from potential blockages.
A novel analysis found that financial strain and food insecurity accelerate biological aging and increase mortality risk, surpassing traditional risk factors. The study emphasizes the need for targeted preventive interventions and patient-centered care to address social determinants of health.
A study comparing GLP-1 RAs found that all three drugs are relatively safe options for patients with type 2 diabetes, with minimal differences in kidney and cardiovascular risks. Liraglutide had a lower risk of all-cause mortality compared to dulaglutide.
Adults with higher levels of physical activity during midlife and late life have a lower risk of all-cause and Alzheimer's disease dementia. This cohort study, part of the Framingham Heart Study Offspring cohort, found similar reductions in risk across different age groups.
Researchers have identified connexin 43 as a vital protein for endothelial repair in mice, which could lead to new therapies to improve recovery and reduce complications after vascular surgery. The study found that the protein helps blood vessels recover after damage, suggesting it could be a target for treatments.
A Cochrane review found that low-dose colchicine reduced heart attacks and strokes in people with a history of heart disease or stroke. The study involved nearly 23,000 participants and showed that taking colchicine could prevent about two of each heart attack and stroke among those with cardiovascular disease.
Researchers from NYU Langone presented practice-changing studies on inflammation, heart attack management, and kidney function in heart failure care. The findings highlight the importance of personalized treatment strategies and balancing effective care with monitoring of kidney health.
A new study found that middle-aged people with higher levels of cardiac troponin I in their blood were more likely to develop dementia in later life. The study also found that damage to the brain seen in people with dementia accumulates slowly over decades before symptoms develop.
A new study analyzing linked electronic health records found that COVID-19 infections led to a higher and longer-lasting risk of rare heart complications, including myocarditis and thrombocytopenia, compared to vaccination. The research team estimated an additional 2.24 cases of myocarditis per 100,000 children after COVID-19 infection.
A simple echocardiography method analyzes myocardial deformation to predict cardiac complications in chronic Chagas disease. The study found that patients with a greater GLS value had a higher risk of death and complications.
The American Heart Association's inaugural CarePlan Challenge recognizes innovators who create digital solutions that transform preventive care, improve disease management and enhance patient engagement. The selected solutions showcase integration of the Association's science-based CarePlans and other digital tools.
Researchers developed an algorithm to optimize pacemaker function usage, reducing battery power consumption and potentially extending battery life by years. By switching off unnecessary features, doctors can reduce the number of surgeries needed and lower associated costs for the NHS.
Researchers have discovered a previously unknown group of cells that produce adrenaline, which may help the fetal heart adapt to stress. The study provides a detailed map of the developing human heart, revealing over 70 distinct cell types and their interactions.
A new study published in The BMJ found that restricting sugar intake during early life is associated with lower risks of heart conditions in adulthood. People exposed to sugar rationing in utero and during their first two years had a 20% reduced risk of cardiovascular disease, as well as slower onset of heart problems.
Researchers used CRISPR technology to identify HMGN1, a nuclear binding protein that contributes to trisomy 21-related CHDs. The study found that an overabundance of HMGN1 leads to abnormal heart development and gene expression.
A landmark study analyzed health data from over 600,000 patients across 10 countries to assess patient risk for non-ST-elevation acute coronary syndrome (NSTE-ACS). The AI-powered model GRACE 3.0 predicts risk more accurately and guides personalized treatment decisions.
A new study from the University of Copenhagen enables researchers to investigate the cause of heart diseases by analyzing thousands of proteins in heart tissue. This groundbreaking method reveals molecular patterns characteristic of heart diseases.
The American Heart Association has acquired the Cardiometabolic Center Alliance program, strengthening efforts to provide holistic management of cardiovascular, kidney, and metabolic health. This partnership aims to expand patient-centered care and improve outcomes for patients with cardiometabolic disease.
Fitter individuals have lower resting heart rates and use fewer total heartbeats per day compared to sedentary people. Regular exercise can improve heart function and reduce long-term cardiovascular risk, according to new Australian research.
A new study found that pediatric athletes' cardiovascular systems adapt to increased fitness with abnormal changes, including increased cardiac mass, central blood pressure, arterial stiffness, and carotid intima-media thickness. These changes are not yet fully understood and may have long-term effects on cardiovascular health.
A multidisciplinary panel published in the Journal of Pediatrics advocates for accelerated diagnosis of familial hypercholesterolemia, a life-threatening genetic condition. Universal lipid screening is recommended to identify affected children at high risk of heart disease decades earlier than those without the condition.
Research from the University of Copenhagen shows that exercising in nature improves mood, reduces stress levels, and boosts heart rate. Participants who exercised outdoors reported greater joy, satisfaction, and optimism than those who exercised in urban or indoor environments.
Dr. Barbara Riegel will be honored for her pioneering research on self-care in patients with chronic illnesses, particularly heart failure. Her work has led to the development of the internationally recognized Self-Care of Heart Failure Index.
The new lab, led by Dr. Annapoorna Kini, will focus on leveraging AI in interventional cardiology, from procedural to educational aspects. The lab aims to optimize complex treatment decisions and improve patient outcomes through AI-powered insights.
Researchers have successfully tested drone-delivered Automated External Defibrillators (AEDs) for out-of-hospital cardiac arrests in the UK. The technology shows promise, but there were delays once the drone arrived on scene, highlighting the need for more support from bystanders and call-handlers.
A new study reveals that blood pressure synchronizes more with predictable phrase structures in music, potentially improving the body's ability to regulate blood pressure. Predictable music structures were found to have a bigger impact on blood pressure than tempo or loudness.