A new study demonstrates the potential to produce cellular spheroids from clinically relevant embryonic stem cells to generate scaffold-free chondrogenic or osteochondrogenic graft tissues. The researchers successfully cultured ES-MSC cellular spheroids, which matured into neocartilage tissues expressing cartilage-associated genes.
Researchers assess ligament maturation and movement impact on scoliotic conditions, providing new insights into the structural hallmarks of embryonic spinal ligaments. The study aims to identify potential connections between embryonic movement and spinal deformities in adolescent idiopathic scoliosis.
Research published in the Journal of Orthopaedic Research reveals that individuals with ACL reconstruction exhibit persistent aberrant gait biomechanics, which can lead to joint loads contributing to long-term knee problems. Early rehabilitative measures may help maintain long-term knee joint health.
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Researchers at Osaka Metropolitan University have found that plasma irradiation can enhance tendon-to-bone junction repair, leading to faster healing rates and stronger repairs. The study used rabbit models to test the effects of plasma on rotator cuff injuries, showing promising results.
A University of Kansas researcher has found that single leg backward hopping can accurately measure knee strength and recovery in patients after ACL reconstruction. This method shows significant changes in knee mechanics compared to forward hopping, making it a potentially superior indicator of quadriceps strength deficiency.
Researchers at Osaka Metropolitan University have discovered that plasma irradiation can accelerate tendon repair, showing faster regeneration and increased strength in lab rats. This breakthrough could lead to shorter treatment times and more reliable tendon healing for athletes and individuals with sports-related injuries.
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A recent study in Brazil found that over 27% of children and adolescents suffer from musculoskeletal pain, with back and leg pain being the most common complaints. The study highlights the need for better understanding and planning of public health policy regarding treatment of chronic pain in adults.
Research by Queen Mary University of London found that girls with obesity are 1.7 times more likely than those with a healthy weight to have at least one GP consultation for musculoskeletal symptoms or diagnosis in childhood. Knee pain was the most common symptom reported, and researchers hope their findings will raise awareness about ...
Researchers at McGill University discovered a new mechanism for the attachment of avian eggshell membranes to their shells. This finding has significant implications for tissue engineering and biomaterial grafts, as well as reducing losses in the commercial egg and poultry industry.
A new forecast projects 1060 million people worldwide will live with 'other' musculoskeletal disorders by 2050, increasing healthcare needs and pressures on stretched systems. Research found these conditions are reported higher in females, increase with age, and peak at 60-69 years.
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The 2020 Tokyo Olympics saw high injury rates in newly introduced sports like BMX freestyle, karate, and skateboarding. However, the overall injury rate was comparable to previous Olympic Games, with lower illness rates. Researchers attribute this to extensive countermeasures against COVID-19
Researchers at University of Jyväskylä used machine learning to predict ACL injuries in elite athletes but found a low overall accuracy rate. The study analyzed the largest data set ever collected and provided valuable insights into the challenges of predicting injuries in individual athletes.
A recent study published in Obesity Reviews found that resistance training, in conjunction with a reduced calorie diet, can lead to significant fat mass and muscle loss. This breakthrough highlights the importance of considering non-aerobic exercise options for individuals struggling with obesity.
A study of over 1,200 agility dogs found that core strength exercises and balance activities can lower the risk of cranial cruciate ligament ruptures. Dogs that engage in high-level agility events and flyball are at higher risk, while those with certain breeds and age factors may also be more prone to injury.
A recent study by researchers from Ritsumeikan University found that athletes with a history of sprained ankle showed reduced gut bacteria diversity compared to those without such a history. This suggests that musculoskeletal injury may have a negative impact on the gut microbiota, potentially leading to long-term health consequences.
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A Henry Ford Health System study published in The American Journal of Sports Medicine found that a novel opioid-free pain management protocol provided the same pain relief for patients as common types of prescription opioids. This approach aims to reduce opioid misuse and promote more effective pain management after ACL knee reconstruc...
A recent study has called for reduced forceps use in Canada and better education for both clinicians and mothers on how to avoid injury during childbirth. The researchers analyzed nearly two million birth records from Canada, Norway, Sweden, and Austria, finding that five percent of women had third or fourth degree tears to the perineum.
A novel computational model predicts that articular cartilage can partially heal after injury by controlling inflammation. The study uses biomechanical and inflammatory aspects of osteoarthritis progression to develop a physics-based computational model.
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Researchers aim to replicate natural tendon development using embryonic chicken and mouse models, with a focus on mechanical stimulation and nanoparticle design.
A study published in Current Rheumatology Reviews found that rehabilitation exercises significantly improved functional strength and reduced weight in knee osteoarthritis patients. The researchers also noted an increase in exercise adherence among the rehabilitation group compared to the control group.
A study of 1,234 revision ACL reconstruction patients found that using an interference screw for femoral and tibial fixation significantly improves six-year clinical outcomes. The transtibial surgical approach also showed improved results in pain and QOL subscales.
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A recent study found that 66.7% of operatively treated gymnast UCL injuries allowed return to competition at an average of 7.5 months, while 100% of non-operatively treated gymnasts RTP, with the latter group showing better scores on multiple patient-reported measures.
Researchers at the University of Tokyo have developed a novel crystal that allows hydrogels to rapidly recover from mechanical stress, making them suitable for medical applications. This breakthrough could lead to more effective treatments for sports injuries and joint pain.
Research highlights the importance of understanding social factors in preventing knee injuries among girls and women. The study suggests that gendered experiences and environmental influences play a significant role in shaping injury outcomes. Experts urge attention to these topics to improve prevention and management strategies.
Researchers at Lund University found that genes contribute more than previously thought to knee injuries, accounting for 69% of cases. The genetic risk was equally high in men and women, suggesting a possible preventive strategy by family members.
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Researchers at the University of Wisconsin-Madison have discovered a potential new treatment for ligament injuries using exosomes and macrophages. The study found that exosome-educated macrophages can promote ligament healing and reduce scarring, with increased collagen production and reduced scar formation.
A team of biomedical engineers developed novel fibre-reinforced hydrogel scaffolds with improved stress resistance and water volume similar to real tendons and ligaments. The synthetic scaffolds aim to fast-track tendon and ligament regeneration, reducing implant failure and improving tissue integration.
A randomized clinical trial compared the effectiveness of two surgical methods: vaginal mesh hysteropexy and hysterectomy with ligament suspension. The study included 175 postmenopausal women and found that vaginal mesh hysteropexy was better at preventing prolapse symptoms, but further research is needed for definitive results.
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Researchers have discovered key molecules that help form the periodontal ligament, a tissue crucial for tooth stability. The study sheds light on how these molecules work together to control cell functions, which could lead to new dental treatments for gum disease and other conditions.
Researchers developed a simplified computational model to predict locations susceptible to post-traumatic osteoarthritis in patients with ligament ruptures. The model identified areas prone to degeneration, suggesting potential pathways for patient-specific clinical evaluation and rehabilitation protocols.
Repetitive knee stress and inadequate rest are key factors behind the rapid rise in ACL injuries, which can lead to chronic health conditions like osteoarthritis. The study provides new evidence that submaximal forces can cause damage to the ACL, contradicting the common view of single force events.
Professional baseball players with low-grade elbow injuries on the humeral side have a higher chance of returning to play and lower risk of ulnar collateral ligament surgery. Lower MRI grade and humeral location are associated with better outcomes.
A new surgical technique significantly reduces graft failure and persistent anterolateral rotatory laxity in young athletes after knee surgery. The study, presented at the American Orthopaedic Sports Medicine Society Annual Meeting, used a lateral extra-articular tenodesis to restore pivot control.
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Patients receiving a hamstring graft have twice the risk of an ACL graft revision compared to those who received a bone-patellar tendon-bone graft. The risk is increased by five percentage points for low-risk patients and 15 percentage points for high-risk patients.
A new mini MRI scanner uses 'magic angle' effect to visualize knee structures, helping diagnose ligament and tendon damage. The technology could reduce NHS waiting times for MRI scans and improve treatment outcomes.
A study found that patients who received more opioid tablets after knee surgery consumed more tablets for longer periods, while those with preoperative education used fewer tablets for shorter durations. Reducing opioid use can lead to better patient outcomes.
Pelvic organ prolapse is a debilitating disorder that affects half of all women over 50. Researchers at Virginia Tech hope to address the problem through new tissue models and surgical mesh grafts. The goal is to develop treatment approaches that are patient-specific, reducing the risk of complications such as pain and infection.
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New research reveals that ligaments hold teeth in place, contradicting previous assumptions. Early dinosaurs like Changchunsaurus parvus had unique tooth replacement methods and wavy enamel.
Researchers have developed a method to 3D-print cells to produce human tissue such as ligaments and tendons, eliminating the need for additional surgeries and reducing reliance on harvested tissue. The technique involves printing stem cells on hydrogel to form tissue that can grow in vitro before implantation.
A new imaging technique using bioinspired camera technology will measure changes in the UCL during loading, providing insight into damage accumulation. The technique aims to improve microstructural evaluation of soft tissues and study biological damage in rotator cuff tendons.
Researchers found that expanding gene-regulatory modules can give rise to new traits, such as the enlarged snout in African cichlid fishes. The study implicated key genetic pathways, including the Tgfβ-Scx pathway and Adam12 protein.
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Researchers used a novel approach to study the movement of ancient birds and reptiles, finding that many assumed poses were impossible due to ligament limitations. This challenges traditional views on pterosaur flight and provides new methods for assessing joint mobility in extinct species.
A new MRI component in the shape of a glove delivers clear images of bones, tendons, and ligaments moving together for the first time. The technology has potential for diagnosing repetitive strain injuries and creating a more versatile atlas of hand anatomy.
The Texas A🏩;M/Virginia Tech team developed image-analysis software to quickly measure key features of nanoporous gold from 150 peer-reviewed papers, correlating them with processing techniques. This allowed the identification of a new parameter and a quantitative law for controlling NPG properties.
New research from Duke University Medical Center found that ACL tears occur the same way in women and men, contradicting previous theories. The study used forensic analysis to examine bone bruises on knees of athletes with torn ACLs, revealing no significant difference in injury mechanism between sexes.
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A study of nearly 300 women found that while most pelvic prolapse surgeries regress over time, symptoms remain significantly improved five years post-surgery. The study suggests that neither procedure might work as well in the long-term as surgeons once thought.
A groundbreaking study has found that injecting DNA into injured horse tendons and ligaments can cure lameness within two to three weeks. The gene therapy technology also showed no adverse side effects, with the horses returning to full health after just two months.
Researchers created a pig model to study human knee growth and changes in ligament orientation during maturity. The model enables researchers to better understand joint injuries in children and teens, potentially informing new surgical approaches and clinical practice.
Researchers found that using techniques that minimize disruption to the lower breast suspensory ligaments improves breast reduction outcomes. The study suggests that preserving these ligaments reduces pseudoptosis, a common long-term complication of breast reduction surgery.
A new review suggests that improved ACL reconstruction techniques can restore normal knee motion and slow degenerative changes associated with osteoarthritis. The placement of a graft on the femur is crucial for preventing cartilage thinning, a key factor in maintaining joint health and function.
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A new study found that consuming gelatin supplements combined with intense exercise can improve collagen synthesis and strengthen engineered lab-grown ligaments. The research suggests a potential role for gelatin and vitamin C in injury prevention and tissue repair.
Researchers found that male rats with normal testosterone levels had stronger ACLs than those without it. The study suggests a link between testosterone and ACL injuries, which could lead to new techniques for identifying athletes at high risk of injury.
Research suggests that the location of ulnar collateral ligament (UCL) tears in MLB pitchers can predict non-operative treatment failures and guide surgical recommendations. Distal UCL tears are more likely to require surgery than proximal tears.
Researchers found that a 20-second pitch clock limit would cause seven percent more arm fatigue in pitchers. This increase in fatigue can strain the ulnar collateral ligament, leading to greater risk of injury, including Tommy John surgery.
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Researchers found that muscle destruction must precede ligament destruction for vertebral retraction to occur. The study's findings have significant implications for understanding the death of dinosaurs like Sinosauropteryx.
Researchers at the University of Missouri have developed a model showing a newer surgical technique results in a stronger, more natural ACL repair. The new suspensory fixation method reduces cell and tissue damage to the graft, allowing for full functional healing.
Researchers found that women who take the birth control pill are less likely to suffer serious knee injuries compared to those who do not use hormonal contraception. Women between 15-19 years old with ACL injuries were 22% less likely to be taking birth control pills.
Using human ligament samples and polarized-light-based imaging, the Penn team has identified microscopic features that prefigure where failure occurs. This insight could lead to new diagnostic techniques or therapies for sub-failure injuries.
A new study reveals that high school female athletes are most likely to experience ACL injuries while playing basketball, soccer, and lacrosse. The rate of injury per exposure is higher in girls than boys, particularly in these high-risk sports.
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A new computer simulation approach found that muscles play a bigger role in injury risk and prevention than previously thought. The study shows that individual pitchers can be at high or low risk of elbow injury depending on their muscle strength, highlighting the importance of targeted training and accurate assessments.