Articles tagged with Single Molecules
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
A University of Houston chemist has received a nearly $2M grant to develop molecular blueprints for controlling how molecules change shape and reactivity upon absorbing light. This research could lead to breakthroughs in storing and using chemical energy, as well as designing materials that change when exposed to light.
Researchers have created a new circuit model that accounts for small changes to the sensor's behavior, allowing it to detect protein or DNA molecules from a sample. The device could lead to earlier diagnosis of diseases and more precise therapies tailored to each patient.
A groundbreaking quantum sensor capable of detecting minute magnetic fields has been developed through international scientific collaboration. The sensor utilizes a single molecule to sense electric and magnetic properties of atoms, offering spatial resolution on the order of a tenth of an angstrom.
The UW–Madison team developed a label-free method to observe individual molecules using an optical microresonator, allowing for the detection of molecules with unprecedented sensitivity. This breakthrough has potential applications in drug discovery and advanced materials development.
Researchers developed a novel compound with nonlinear photochromic properties, achieving enhanced contrast and spatial resolution. The compound exhibits improved coloration efficiency with higher-intensity light, enabling diverse applications in photolithography, 3D printing, and optical disks.
Researchers developed a method to observe single protein vibrational spectra using near-field optical microscopy, enabling detailed analysis of extremely small samples. The technique represents a major breakthrough for ultra-high sensitivity and super-resolution infrared imaging, as well as single-molecule vibrational spectroscopy.
A new study reveals that molecules can interact non-reciprocally without external forces, driven by kinetic asymmetry and gradients of reactants and products. This finding has significant implications for our understanding of complex behavior in living organisms and the development of novel molecular machines.
Researchers at Curtin University have created a piezoresistor the size of a human hair, revolutionizing chemical and biosensors. This breakthrough enables detection of diseases through molecular shape changes, offering new possibilities for health monitoring devices.
Researchers at the University of Missouri have developed a new method using nanopores to advance discoveries in neuroscience and medical applications. The technique allows for real-time detection of dynamic aptamer-small molecule interactions, which can aid in understanding DNA and RNA diseases and drug discovery.
The GEMINI blood test uses machine learning to identify cancer-causing mutations in single molecules of cell-free DNA. The test detected over 90% of lung cancers, including stage I and II cases, in a proof-of-concept study published in Nature Genetics.
A recent study by Tokyo Tech researchers explores the structure and electron transport properties of molecular junctions. The findings reveal three distinct structures at the junction, corresponding to high- and low-conductivity states, which hold promise for designing novel electronic devices with unique properties.
Researchers have developed a new material for single-molecule electronic switches, which can vary current at the nanoscale in response to external stimuli. The ladder-type molecular structure enhances stability and makes it promising for use in single-molecule electronics applications.
The new ultrafast camera technology allows scientists to observe the movement and binding of molecules within living cells with unprecedented precision. This enables researchers to study cancer spread and develop new drugs by revealing deeper understanding of cellular structures like focal adhesions.
A study published in Communications Biology reveals that a large portion of an insulin dose may not be effective, providing a tool for developing more precise medications. The discovery could lead to improved treatment outcomes for millions of people worldwide.
Researchers at University of Tokyo's Institute for Solid State Physics have demonstrated a switch made from a single fullerene molecule that can function as multiple high-speed switches simultaneously. This technology could lead to unprecedented levels of resolution in microscopic imaging devices.
Researchers at Argonne National Laboratory have developed a way to rotate a single molecule, europium complex, clockwise or counterclockwise on demand. This technology could lead to breakthroughs in microelectronics, quantum computing and more.
A team of researchers has developed a prototype of a quantum microscope that can see electric currents, detect fluctuating magnetic fields, and even see single molecules on a surface. The microscope uses atomic impurities and van der Waals materials to achieve high resolution sensitivity and simultaneous imaging of magnetic fields and ...
Scientists have successfully created two types of light-driven molecular motors that can both rotate and fluoresce in the same molecule. This achievement demonstrates that these motors can be designed to control various functions using light energy, paving the way for potential applications in biomedical imaging and cellular processes.
Researchers at ICIQ have demonstrated that single molecules can retain properties even when the stimulus disappears, breaking previous expectations. This discovery has significant implications for molecular data storage and could lead to new possibilities for storing multifunctional information.
Researchers at the Max Born Institute have used novel ultrashort soft X-ray spectroscopy to study the fate of molecular nitrogen when an electron is kicked out. They found that the B state has a similar degree of excitation as the X state, contradicting previous models. Instead, a coherent interplay between light fields enables lasing ...
Researchers at POSTECH have developed a method to observe single molecules at room temperature, revealing their structural dynamics and conformational heterogeneity. This breakthrough has significant implications for understanding the origin of life, identifying causes of incurable diseases, and developing treatments.
A new DNA-based fluorescence technique using single-molecule electron-transfer kinetics can identify point mutations in mRNA, facilitating the diagnosis of gliomas and potentially treating the disease. This breakthrough may lead to real-time cancer diagnostics during surgical biopsies, reducing the need for multiple surgeries.
Scientists have developed a method to control chemical reactions in a single molecule by applying voltage pulses, resulting in unprecedented selectivity. By fine-tuning the voltage, researchers can interconvert different products formed during the reaction.
A new study from Tokyo Institute of Technology introduces a novel crystal engineering strategy to design ultrabright fluorescent solid dyes. This approach allows for monomeric emission and suppressed intermolecular interactions, enabling the creation of highly dense crystalline structures with controlled electronic properties.
Columbia researchers built a 2.6nm-long single molecule wire that exhibits an unusual increase in conductance as the wire length increases and has quasi-metallic properties. The breakthrough overcomes the exponential-decay rule, enabling electronic devices to become even tinier.
Researchers from Kumamoto University create nanocavities using ovalene molecules on gold electrodes, trapping a single thiol molecule. This breakthrough enables precise molecular design for future electronic devices and sensors.
Researchers at Chalmers University of Technology have developed a groundbreaking microscopy technique that allows for the study of proteins, DNA, and other biological particles in their natural state. This innovation enables earlier detection of promising drug candidates and provides valuable insights into cell communication processes.
Researchers at Peking University developed a microsensor that leverages whispering gallery modes to detect single DNA molecules with improved sensitivity. The interface mode outperforms traditional evanescent field-based sensors, offering ultra-small sample consumption and automatic analysis capabilities.
Researchers at Arizona State University have developed a new microscopy method that can track 100 single molecules simultaneously in three dimensions. The technique uses surface plasmon resonance (SPR) technology to precisely image molecular binding events and study their dynamic activities in real time.
Researchers successfully manipulated a single molecule into an upright position and measured its stability, gaining insights towards fabricating electrical components and circuits at the atomic level. The findings have potential applications in creating ultrasensitive sensors, quantum dots, and quantum computers.
Researchers have successfully imaged the spin of an individual molecule using electron spin resonance in a scanning tunneling microscope. This achievement allows for precise control of spin states and investigation of magnetic interactions between molecules.
The university will acquire an optical tweezer to study colloidal copolymer chains, protein binding strength and other phenomena. The instrument will be made available to Rice researchers and collaborators.
Scientists at the University of Graz successfully transfer single organic molecules along a specific direction on a silver surface, demonstrating precise control over their movement. The experiment uses electrostatic forces to move molecules up to 150nm with high precision and speed.
Researchers from the University of Exeter's Living Systems Institute use light to monitor individual molecule structure and properties in real-time. The team temporarily bridges molecules together, allowing for crucial insight into their dynamics.
Researchers at the University of Basel developed a non-invasive technique to study individual molecules precisely. The new force spectroscopy method detects molecular vibrations without perturbing its quantum state.
Scanning Raman picoscopy enables visualization of vibrational modes and direct construction of molecule structures. Researchers achieve Ångström-resolved imaging, correlating local vibrations with constituent groups to assemble molecules in real space.
Molecular electronic devices use molecules to build ordered systems with quantum effects, offering advantages like small volume, easy synthesis, and high efficiency. However, research is still theoretical, and device manufacturing reliability, repeatability, and cost need improvement.
Researchers at Johannes Gutenberg University Mainz have synthesized novel liquid crystals that can conduct electrical energy along their length. The materials, dubbed 'power cables', possess an additional advantage: they self-heal if ruptured, eliminating the need for complex repairs.
Researchers at University of Göttingen developed a new method using graphene to measure the distance of single molecules from the sheet, allowing for high accuracy in optical resolution. The technique enabled the measurement of single lipid bilayers with nanometre resolution, advancing super-resolution microscopy.
Researchers developed a programmable device that integrates nanopores and optofluidic technology for controlling individual molecules and particles on a chip. The device enables selective analysis of target molecules from a mixture, allowing for high-throughput single-molecule analysis.
Researchers at Arizona State University have developed new methods using data science to analyze the motion of single molecules. By leveraging Bayesian nonparametrics, they can efficiently detect and refine signals, reducing acquisition times and increasing the scope of biological research.
An international team of researchers has successfully measured how heat passes between two gold electrodes through a single molecule. The study employed a scanning thermal microscope to detect the vibrations of atoms in an alkane molecule carrying the heat, providing valuable insights into thermal conduction at the molecular scale.
Researchers demonstrate polymers' potential in fabricating single-molecule electronic devices, yielding better properties and stability than monomers. The study reveals the possibility of using polymers as building blocks for future electronics miniaturization.
Researchers have created a sensor that can measure and image magnetic structures at the atomic scale, enabling new directions in atomic-scale research. The sensor uses a single molecule magnet as a scanning magnetometer to detect spin-spin interactions between molecules.
Researchers have created a new breed of devices with unique properties, harnessing the power of quantum interference to fine-tune electrical conductance. By controlling quantum strangeness, they demonstrated that electrical conductance can be modulated over two orders of magnitude in single molecules.
Researchers have developed nanoscale tweezers that can perform single-molecule 'biopsies' on individual cells, extracting DNA, proteins, and organelles without destroying the cell. This technique could help scientists build a 'human cell atlas' and better understand fundamental cellular processes.
Researchers at Osaka University have developed an AI-based system to track individual fluorescently labeled molecules in living cells. The system can analyze hundreds of thousands of molecules in a short period, providing reliable data on molecule status and dynamics.
A standardized protocol for FRET has been established, enabling precise measurement of distances within biomolecules. This breakthrough methodology can overcome size and stability limitations of other structural biology methods, leading to targeted drug development and new research opportunities.
The Forschungszentrum Jülich team successfully oriented a platelet-shaped PTCDA molecule as desired using a scanning probe microscope. The molecule is surprisingly stable in the upright orientation and can be used to create new electronic functionalities, such as logic and sensor circuits.
Researchers at Tokyo Institute of Technology developed a 4.5-nm-long molecule that forms coherent resonant electron-tunneling devices, exhibiting thermal stability similar to traditional materials. The discovery paves the way for future molecular-scale electronic research and addresses limitations in conventional electronics.
Scientists have successfully trapped and manipulated two individual sodium and cesium atoms using optical tweezers, resulting in the creation of a new sodium-cesium molecule. This technique enables precise control over chemical reactions, paving the way for studying complex molecules and designer molecules for quantum applications.
Researchers have developed graphene narrow stripes to use as electrical wires and a method to precisely contact individual molecules. The discovery has enabled direct atomic precision contacting, leading to the creation of a single-molecule magnetic device.
Researchers from IOCB Prague and IP CAS demonstrate a strong converse piezoelectric effect at individual molecules of heptahelicene derivative on a silver surface. The study provides new insights into the electromechanical behavior of individual molecules, opening up possibilities for nanoscale molecular devices.
Researchers have made a breakthrough in storing data with single molecules, achieving magnetic hysteresis at -213 °C, which is close to the temperature of liquid nitrogen. This discovery could lead to more energy-efficient data storage and reduce greenhouse gas emissions.
Researchers have discovered an organic material with record-high electrical conductance, exceeding that of traditional metals and semiconductors. The antiaromatic molecule displays superior conductivity due to its unique electronic structure, which allows it to efficiently transport electrons.
A Japanese collaboration led by Osaka University has developed a method to detect unique signatures from single molecules using carbon nanotube-based devices. The researchers found that different molecules produced distinct noise signals related to their properties, allowing for the prediction of molecular interactions.
Researchers at Osaka University investigated the geometry of single molecule-electrode contacts on thermoelectric behavior. They found that the largest thermoelectric effect was observed for structures containing a stretched thiol linkage, which shifts the energy level to a more favorable position.
Researchers successfully demonstrated a reliable and reproducible single molecule switch, enabling electric current to flow between electrodes through the molecule or not. The breakthrough could lead to advancements in molecular electronics.
Researchers at OIST have developed a new strategy for producing photoluminescent compounds by combining the flexibility of weak aggregation-driven complexes with the controllability of conventional metal-ligand systems. This results in molecules that can be tuned to emit light of specific colors based on their structure.
Researchers used an STM to study changes in single-molecule shape and found that the tip's position impacts energy requirements and entropy. The team observed changes in energy barriers and attempt rates at low temperatures, linking entropy to fundamental physical parameters.