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Answer ALS Launches AI drug development collaboration with Tulane, Pennington Biomedical Research Center and GATC Health to advance ALS treatment discovery

Answer ALS is launching a groundbreaking collaboration with Tulane University and the Pennington Biomedical Research Center to harness AI for ALS treatment discovery. The Louisiana AI Drug Development Infrastructure for ALS (LADDIA) will prioritize therapeutic targets using AI-driven insights from the Answer ALS' Neuromine Data Portal.

Dr. Adithya Hari joins Pennington Biomedical as physician/nuclear oncologist, adds to center’s strategic expansion of cancer metabolism program

Pennington Biomedical welcomes Dr. Adithya Hari, MD, with expertise in nuclear oncology and translational science, strengthening cancer research and patient-centered innovation in Louisiana. He will establish a research program focused on nuclear medicine and dedicate time to direct patient care through a clinical partnership.

Pennington Biomedical Research Center investigates tirzepatide's role in weight loss and metabolic health

Researchers at Pennington Biomedical Research Center investigated tirzepatide's effects on weight loss and metabolic health. The study found that tirzepatide decreased calorie intake and increased fat oxidation, leading to significant weight loss. However, the drug did not decrease the slowing down of metabolic rate usually observed wi...

SourcePennington Biomedical Research Center·JournalCell Metabolism·TypeRandomized controlled/clinical trial·DateApr 24, 2025

Doctors group files complaints, asks Oregon Health & Science University to shut down invasive reproductive experiment on primates

The Physicians Committee for Responsible Medicine has filed complaints with OHSU, the USDA, and NIH, asking for an invasive reproductive experiment on nonhuman primates to be shut down due to cruelty and scientific unnecessaryness. The experiment aims to investigate how chronic THC use affects fertility in primates.

Simulating protein structures involved in memory formation

Researchers developed a computational model that reproduces intricate protein structures at postsynaptic densities, crucial sites for learning and memory. The model reveals details on how these proteins organize into unique structures through liquid-liquid phase separation, enabling sustained activation of downstream signaling pathways.

SourceFujita Health University·JournalCell Reports·TypeComputational simulation/modeling·DateApr 16, 2025

SMART researchers develop novel UV and machine learning-aided method to detect microbial contamination in cell cultures

A new method using UV light and machine learning can detect microbial contamination in cell cultures, providing a quicker yes/no assessment within 30 minutes. This technology aims to reduce the time spent on sterility tests, making it crucial for life-saving treatments.

SourceSingapore-MIT Alliance for Research and Technology (SMART)·JournalScientific Reports·TypeExperimental study·DateApr 13, 2025

Mesenchymal stem cell-derived extracellular vesicles improve survival in mice exposed to high-dose irradiation

A new study found that mesenchymal stem cell-derived extracellular vesicles significantly enhance survival and facilitate substantial peripheral blood recovery in mice exposed to high-dose irradiation. The treatment promoted hematopoietic recovery, with increases in red blood cell, platelet, white blood cell, and hemoglobin levels.

SourceMary Ann Liebert, Inc./Genetic Engineering News·JournalStem Cells and Development·TypeExperimental study·DateApr 9, 2025

'Milestone' discovery may unlock the true biomedical might of natural containers called exosomes

Scientists at Virginia Tech have developed a method to produce, store, and deliver exosomes containing wound-healing compounds for targeted drug delivery and diagnostics. The breakthrough process improves stability for up to a year at room temperature, enabling mass production and commercial implementation.

SourceVirginia Tech·JournalJournal of Biological Engineering·TypeExperimental study·DateApr 9, 2025

A new smartphone-sized device can test for tuberculosis. Here’s why that matters for children

Tulane University scientists developed a handheld device to deliver rapid and accurate tuberculosis diagnoses in under an hour. The device, called the lab-in-tube assay (LIT), can detect Mycobacterium tuberculosis DNA in saliva, blood, and sputum samples, offering a cost-effective tool for improving TB diagnoses in resource-limited areas.

SourceTulane University·JournalScience Translational Medicine·DateApr 9, 2025

University of South Florida’s medical school ranked No. 1 in the state, among nation’s top tier by U.S. News & World Report

The USF Health Morsani College of Medicine has been named the top-ranked medical school in Florida and received a Tier 1 ranking from U.S. News & World Report, reflecting its world-class research and educational programs. The college's recent achievements include record-breaking $738 million in research funding and a significant increa...

Community Review Board votes against public health care merger in Oregon after doctors group raises concerns about university’s primate research center

The Community Review Board voted unanimously to reject the merger, citing OHSU's history of federal Animal Welfare Act violations and unnecessary experiments on monkeys. The Physicians Committee for Responsible Medicine has been calling for the closure of OHSU's primate research facility, which houses over 5,000 monkeys.

Multiple proteins viewed as never before

The CombPlex technology developed at Weizmann Institute allows for the simultaneous imaging and quantification of nearly two dozen proteins within individual cells. This breakthrough enables researchers to measure lots of proteins at the same time, crucial for understanding tissue function and disease processes.

SourceWeizmann Institute of Science·JournalNature Biotechnology·DateApr 7, 2025

circTP63-N suppresses the proliferation and metastasis of nasopharyngeal carcinoma via engaging with HSP90AB1 to modulate the YAP1/Hippo signaling pathway

A novel circular RNA, circTP63-N, generated by back-splicing exons 2–4 of the TP63 gene is significantly downregulated in nasopharyngeal carcinoma (NPC) tissues. Restoring its expression effectively inhibits NPC cell proliferation and metastasis via engagement with HSP90AB1 to modulate the YAP1/Hippo signaling pathway.

SourceScience China Press·JournalScience China Life Sciences·DateApr 3, 2025

Pennington Biomedical’s Dr. Leanne Redman honored with the E. V. McCollum Award from the American Society for Nutrition

Dr. Leanne Redman, a leading authority on body weight regulation, has received the prestigious E.V. McCollum Award for her translational research on maternal nutrition and energy regulation, with significant impact on public health. The award recognizes her dedication to advancing research that improves women's and families' health.

Adulting is hard on the heart: Teen to young adulthood is a critical time to address risk

Many teenagers enter adulthood with significant risk factors for cardiovascular disease, and emerging adulthood is a key time to address these risks. Interventions such as health practices, lifestyle changes, and improved access to healthcare can help reduce the risk of developing future cardiovascular disease.

SourceAmerican Heart Association·JournalJournal of the American Heart Association·DateMar 26, 2025

Build it and they shall come

A study conducted at Osaka Metropolitan University found that the opening of a multifunctional facility called ONIKURU significantly increased residents' daily walking time, especially among female young adults. The results suggest that such architecture-scale interventions can contribute to building health-promoting environments.

SourceOsaka Metropolitan University·JournalScientific Reports·TypeData/statistical analysis·DateMar 26, 2025

Study: new guidelines expanded access to lung cancer screening, but gaps remain in reaching rural and uninsured populations

The updated guidelines substantially increased lung cancer screenings overall, but disparities persist among people with limited access to healthcare. Barriers include cost, knowledge, and lack of primary care providers, with mobile units and patient navigators offering potential solutions.

Scientists test accessible, affordable diagnostic tool for heart disease risk via molecular blood screening

Scientists have developed a low-cost and easy-to-use diagnostic tool for assessing cardiovascular disease risk using molecular blood screening. The technology enables high-throughput analysis of key lipoprotein markers in under 15 minutes, providing clinicians with a rapid and reliable diagnostic tool.

SourceMurdoch University·JournalAnalytical Chemistry·TypeExperimental study·DateMar 19, 2025

Can AI help detect cognitive impairment?

Researchers developed a portable system using AI to spot cognitive impairment by measuring subtle differences in motor function. The device accurately identified 83% of participants with mild cognitive impairment (MCI), offering potential for early intervention and improved outcomes.

SourceUniversity of Missouri-Columbia·JournalAlzheimer Disease & Associated Disorders·DateMar 13, 2025

The flicker reveals the mechanisms of vision. Groundbreaking f-ORG technique can advance the diagnosis of retinal diseases

A new diagnostic method called flicker optoretinography (f-ORG) analyzes the retina's reaction to light, helping to detect danger before symptoms appear. The technique detects even minor changes in photoreceptors, providing valuable insights into retinal health.

SourceInstitute of Physical Chemistry of the Polish Academy of Sciences·JournalProceedings of the National Academy of Sciences·DateMar 12, 2025