Articles tagged with Endocrine Diseases
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Exposure to single and mixtures of perfluoroalkyl substances (PFAS) was associated with higher odds of endocrine disruption (ED) among women. Certain PFAS compounds, particularly n-PFOS, were found to disrupt endocrine function and harm health.
Dr. Anna Gloyn has been awarded the fifth Transatlantic Alliance Award for her pioneering research on genetic mechanisms of diabetes and precision medicine. Her collaborative work with colleagues across Europe and the United States has significantly advanced our understanding of the genetic basis of diabetes.
A new study found that maternal thyroid hormones are crucial for fetal neurodevelopment, and gestational thyroid imbalance increases the risk of autism spectrum disorder. Women with persistent thyroid dysfunction across pregnancy were at a higher risk of having children with autism.
The European Society of Endocrinology has published a revised clinical practice guideline for the treatment of chronic hypoparathyroidism in adults, featuring a new definition and treatment algorithm. The guidelines aim to provide practical guidance for healthcare providers involved in diagnosing and managing the condition.
The European Society of Endocrinology (ESE) has announced the winners of the 2026 ESE Awards, which recognize outstanding contributions to improving knowledge and expertise in endocrinology. This year's winners include Martin Reincke for his work on neuroendocrinology and Maria-Christina Zennaro for her research on hypertension.
The European Society of Endocrinology has published a new Clinical Practice Guideline for the Management and Evaluation of Menopause and the Perimenopause. The guideline provides guidance on evaluating and managing women with menopause-related symptoms, including hormone therapy benefits and risks. It also discusses alternative treatme...
The European Society of Endocrinology has released the EndoCompass Research Roadmap, a major new initiative to align research efforts and improve funding strategies for hormone-related health challenges. The roadmap identifies specific research needs across eight endocrine specialties and five cross-cutting areas.
The Pennington Biomedical Research Center has opened a new Endocrinology and Diabetes Clinic in Baton Rouge, providing specialized care for patients managing diabetes and endocrine disorders. The clinic is led by Dr. Timothy Gilbert, who brings nearly 20 years of private practice experience to the region.
A new study found that adolescents with higher blood levels of per- and polyfluoroalkyl substances (PFAS) prior to bariatric surgery regained more weight and had greater increases in waist circumference up to five years after surgery. Researchers believe PFAS exposure disrupts endocrine and metabolic processes, leading to weight regain.
A new study by The Endocrine Society finds a strong link between acromegaly and an increased risk of various cancers, often at younger ages than expected. Patients with the rare growth hormone disorder had higher rates of certain types of cancer, including colon, gastric, breast, lung, ovarian, prostate, and blood cancers.
A new study found that intermittent energy restriction significantly improved fasting blood glucose and triglycerides, while also increasing insulin sensitivity. The IER group showed the greatest advantages in reducing these markers compared to time-restricted eating and continuous energy restriction groups.
Cancer deaths linked to obesity have increased sharply in the US, especially among women and older adults, with sharp regional disparities. The study highlights the need for targeted public health strategies to address this growing public health crisis.
A recent study published by The Endocrine Society found that osteoporosis treatment after a fracture can decrease both hospitalization and mortality in people older than 80. Researchers analyzed data from 88,676 patients aged 80 and older who suffered a fracture due to bone deterioration or weakness caused by osteoporosis.
A small study found that consuming more protein may help prevent muscle loss in adults with obesity taking semaglutide, an anti-obesity medication. The researchers noted that older adults and women may be at higher risk for muscle loss, emphasizing the importance of preserving muscle during weight loss with this medication.
A real-world study of 120 postmenopausal women found that using tirzepatide and menopause hormone therapy simultaneously led to superior total body weight loss percentage compared to using tirzepatide alone. This combined treatment also resulted in a higher percentage of participants achieving at least 20% weight loss.
Researchers found that tirzepatide reduced body weight and body fat by approximately 20% in mice, resulting in a significant reduction of tumor volume. The study suggests that this new anti-obesity drug may have a beneficial impact on breast cancer outcomes.
A landmark review highlights how diabetes alters bone microarchitecture and increases fracture risk in people with type 2 diabetes, despite normal or elevated bone mineral density. The authors advocate for updated diagnostic tools, including a revised TBS algorithm, to more accurately reflect bone quality in individuals with central ob...
The Endocrine Society supports the bipartisan legislation to ensure people living with obesity have access to effective treatments. The bill will cover anti-obesity medications and intensive behavioral therapy, addressing the chronic disease's complications like cancer, type 2 diabetes, and heart disease.
Professor Sadaf Farooqi has been awarded the inaugural Joint ‘Endocrinology Across the Life Course Award’ for her groundbreaking research on human eating behaviour and severe childhood obesity. Her work has changed attitudes towards people with severe obesity by demonstrating its biological basis.
The inaugural Joint Congress brings together paediatric and adult endocrine specialists to learn from each other, collaborate, and celebrate endocrinology. Over 7,500 delegates from 100 countries attend the event to experience the latest research and developments.
The event aims to create a positive scientific and policy legacy from the Congress in Denmark, Europe, and internationally. The conference will focus on key research presented at the Joint Congress and future priorities from the EndoCompass Research Roadmap.
Dr. Seymour Reichlin's remarkable career spanned five decades, marked by scientific excellence, mentorship, and generosity. His influence on neuroendocrinology has been profound, with ongoing contributions at age 100 revealing new insights into Alzheimer's disease and ecstatic mysticism.
The European Society of Endocrinology and the European Hormone and Metabolism Foundation launch a global campaign to raise awareness about hormone balance and its impact on chronic diseases. Small steps can make a big difference in improving hormone health.
Professor Atsushi Suzuki, Chair of Endocrinology at Fujita Health University School of Medicine, Japan, received the IOF President's Award for his exceptional contributions to IOF. He has shared his expertise as a mentor and engaged member of the Capture the Fracture Governance.
Dr Ambrish Mithal, an Indian endocrinologist, has been awarded the prestigious IOF CSA Medal of Achievement for his groundbreaking work in advancing the field of osteoporosis. His pioneering efforts have significantly increased understanding and awareness of osteoporosis globally.
The Endocrine Society strongly disagrees with the administration's decision not to finalize a rule allowing Medicare and Medicaid to cover anti-obesity medications. This decision leaves millions of Americans with obesity without access to evidence-based treatment, exacerbating the country's growing obesity epidemic.
A new consensus paper emphasizes the role of bone turnover markers (BTMs) in diagnosing and managing osteoporosis. BTMs, such as procollagen type I N propeptide (PINP) and β-isomerized C-terminal telopeptide of type I collagen (β-CTX-I), are invaluable tools for predicting fracture risk and monitoring treatment adherence.
A new study reveals a cell atlas of the endometrium in women with PCOS, showing distinct differences in cellular composition and gene expression. The findings suggest that targeting specific cell types may lead to better treatment options for women with PCOS and related reproductive issues.
The Endocrine Society calls for the reinstatement of the Diabetes Prevention Program, which has been halted by government funding cuts. The program, spanning three decades, found that lifestyle changes or metformin could prevent or delay type 2 diabetes in at-risk individuals, with a notable 58% risk reduction through 5%-7% weight loss.
Breast cancer survivors experience accelerated aging due to detrimental effects of BC and its treatments, particularly systemic therapies. The study highlights the need for ongoing monitoring and potential strategies to slow down aging in cancer survivors.
Finnish researchers found pituitary macrophages regulate hormonal balance and may be used to treat endocrine disorders. Macrophages have a local effect on hormone secretion, decreasing when removed.
The European Society for Paediatric Endocrinology and the European Society of Endocrinology will host the first-ever joint Congress on May 10-13, 2025. The event aims to bring together paediatric and adult endocrine specialists from across Europe and the world to collaborate and celebrate endocrinology.
Researchers investigate how sex-specific immune responses affect disease outcomes in obesity and helminth infections, aiming to develop new treatments for metabolic disorders and parasitic infections. The study focuses on macrophage-eosinophil interactions and the role of RELMalpha protein.
The European Society of Endocrinology (ESE) and ESE Foundation will host the first-ever World Hormone Day on April 24, 2025. The campaign aims to raise public awareness of good hormone health and improve national political engagement for better prevention, diagnosis, and treatment of endocrine disease.
A study led by Henry J. Pownall and Khurram Nasir found a strong link between the amount of free cholesterol in HDL and its accumulation in macrophages, which can contribute to heart disease. The researchers aim to develop new diagnostics and treatments for managing heart disease using HDL-free cholesterol as a biomarker.
A new animal study published in the Journal of the Endocrine Society found that early life exposure to polychlorinated biphenyls (PCBs) may lead to behavioral problems in rats. PCBs, which have been banned for decades, can reprogram a developing neuroendocrine system and cause developmental and hormonal changes.
Women with infertility are at higher risk of developing SARD, including lupus and Sjögren's syndrome, even after accounting for pre-eclampsia and other pregnancy complications. Infertility treatments do not appear to increase this risk, suggesting that women may be undiagnosed or untreated.
The landmark review charts the transformation of pituitary tumor treatment from early hormone regulation experiments to modern precision therapies. Key findings include significant advances in prolactinoma and acromegaly treatments, as well as emerging areas for research like receptor modulators and immunotherapy.
Researchers from Universidad Miguel Hernandez de Elche found that bisphenol analogs BPF and BPS, marketed as safer alternatives to BPA, accumulate in biological membranes and disrupt endocrine function. The study suggests these compounds pose health risks similar to those of BPA.
An analysis of pancreatic cancer data found an increasing incidence among young adults, but stable mortality rates, suggesting detection of previously undetected disease. The study highlights the need for caution against overdiagnosis and high-risk surgery.
A recent study found that vitamin D supplementation can decrease blood pressure in older adults with obesity and those with low vitamin D levels. High doses of vitamin D did not provide additional health benefits compared to the recommended daily dose.
The International Osteoporosis Foundation's Capture the Fracture campaign highlights top-performing Fracture Liaison Services that deliver gold-standard care. These services prioritize continuous care, tailored treatment plans, and teamwork to reduce secondary fractures and improve patient outcomes.
The Endocrine Society's new statement highlights research gaps on opioids' effects on the endocrine system, which can lead to conditions like male hypogonadism and secondary adrenal insufficiency. Clinicians need to monitor patients using opioids for signs of these health consequences.
A low-carbohydrate diet may improve beta-cell function in people with type 2 diabetes, allowing them to better manage their disease and possibly discontinue medication. The study found that participants on a low-carb diet showed significant improvements in acute and maximal beta-cell responses compared to those on a high-carb diet.
A team of researchers has developed strategies to identify regulators of intestinal hormone secretion, which could lead to new treatments for metabolic and gut motility disorders. They used human organoids to study the function of 'nutrient sensors' on hormone-producing cells in the gut.
The Endocrine Society's inaugural Artificial Intelligence in Healthcare Virtual Summit will explore AI's potential to improve medical care, advance research, and leverage big data. Key sessions will discuss predictive analytics, machine learning algorithms, and natural language processing.
A Carnegie Mellon-led team has secured a $42 million grant to develop implantable, cell-based bioelectronic devices for real-time therapy and disease monitoring in patients with thyroid disorders. The devices will offer adjustable, low-cost treatment and continuous biomarker measurement.
Regular moderate coffee or caffeine intake is associated with a lower risk of new-onset cardiometabolic multimorbidity. The study found that moderate consumption could play an important protective role in almost all phases of CM development.
A deadly marine cone snail's venom contains a toxin that interacts with human cells in a specific manner, regulating blood sugar levels and hormone balance. This discovery may lead to the design of more effective drugs for treating diabetes and endocrine disorders.
Scientists have developed a new compound, ZTA-261, which selectively binds to the thyroid hormone receptor beta (THRβ) to treat lipid disorders. Mice administered the drug showed decreased lipid levels in the liver and blood with fewer side effects compared to existing compounds.
Research reveals TRPV4 complex promotes sweat secretion in mouse foot pads, suggesting its potential role in human perspiration. The study also suggests that TRPV4 may regulate friction forces, which could impact traction on hind paws.
A new global definition of sarcopenia is proposed, aiming to unify research and clinical practice. The definition may help identify low muscle mass or strength in older people, increasing the risk of poor outcomes such as fragility and disability.
The IOF position paper emphasizes the need for population-specific vitamin D approaches, considering factors like diet, skin pigmentation, and supplement use. The authors also highlight the importance of standardized measures of 25(OH)D in future studies.
Researchers found that patients wearing a brain-tracking headband while meditating experienced improved physical functioning and reduced body pain after surgery. The MUSE-2 device provides audio biofeedback to aid meditation.
Research presented at ENDO 2024 found that older women with low bone density are more likely to experience their first hip fracture in their 60s. A study analyzing NHANES data revealed a significant increase in osteoporosis, but surprisingly, a decrease in fragility hip fractures between 60-70 years.
A study found that patients with thyroid eye disease who received teprotumumab infusions maintained efficacy 51 weeks after treatment. Nearly two years later, 82% of patients did not require additional treatment for their condition.
Research reveals a three times greater risk for metabolic-dysfunction-associated steatotic liver disease in women with moderate-to-severe vasomotor symptoms compared to those with mild symptom severity. The study highlights the importance of addressing hot flashes and night sweats to assess cardiovascular health.
Researchers found that GLP-1 receptor agonists and SGLT-2 inhibitors lower the risk of major cardiovascular events, such as heart attacks, and severe liver complications compared to other diabetes treatments. These medications also showed no significant increase in severe adverse events.
A new study found that children who are sedentary for more than six hours a day have a significantly increased risk of severe fatty liver disease and liver cirrhosis by young adulthood. Engaging in light-intensity physical activity for at least 3 hours a day can reverse premature liver damage.
Researchers at UCSF have identified laryngeal and tracheal neuroendocrine cells that sense water and acid in the upper airway, triggering a cough reflex. The discovery could lead to interventions to prevent pneumonia and treat certain types of chronic cough.