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Early weight gain is linked to lifelong health consequences

A study of over 600,000 people found that early weight gain is associated with a higher risk of dying from various diseases, particularly cardiovascular disease and type 2 diabetes. Weight gain during adulthood also increases the risk of premature death, especially for those who develop obesity at a younger age.

SourceLund University·JournalEClinicalMedicine·TypeObservational study·DateApr 10, 2026

Clotting factor concentrate better than frozen plasma for preventing bleeding after heart surgery, according to clinical trial results

A clinical trial has shown that administering clotting factor concentrate (4F-PCC) significantly reduces the risk of severe bleeding after major open-heart surgery. This innovative treatment approach offers a more effective alternative to frozen plasma for managing surgical bleeding.

SourceUniversity of Oklahoma·JournalJAMA·TypeRandomized controlled/clinical trial·DateApr 1, 2025

30-year risk of cardiovascular disease may help inform blood pressure treatment decisions

A new study published in Hypertension journal suggests that both 30-year and 10-year risk predictions should be considered when making high blood pressure treatment decisions. The researchers compared two risk prediction tools and found that long-term, 30-year risk may be more important than short-term, 10-year risk for informing medic...

SourceAmerican Heart Association·JournalHypertension·DateJul 15, 2024

Salt substitutes help to maintain healthy blood pressure in older adults

A recent study published in the Journal of the American College of Cardiology found that salt substitutes can help maintain healthy blood pressure in older adults. The study, which included 611 participants, showed that those using salt substitutes had a 40% lower incidence of hypertension compared to those using regular salt.

SourceAmerican College of Cardiology·JournalJournal of the American College of Cardiology·DateFeb 12, 2024

Study highlights optimal timing for assessing orthostatic hypotension in older adults and its impact on fall risk

A new study found that orthostatic hypotension assessments conducted after 4-6 minutes of standing are more informative for predicting fall risk in older adults. This timely assessment can help clinicians identify those at highest risk and institute appropriate interventions to reduce falls.

SourceHebrew SeniorLife Hinda and Arthur Marcus Institute for Aging Research·JournalJournal of the American Geriatrics Society·DateNov 6, 2023

Red blood cell transfusion in the ICU

Red blood cell transfusions were common in ICU patients globally, with overlapping reasons for use despite differing clinical contexts. The three most common triggers for transfusion (hypotension, tachycardia, hemodynamic instability) were largely consistent across regions.

SourceJAMA Network·JournalJAMA·DateOct 12, 2023

New Jersey Health Foundation awards grants to Kessler Foundation to advance research in brain and spinal cord stimulation methods

Two Kessler Foundation scientists will conduct studies on upper extremity exercise after stroke and restoration of cardiovascular function in spinal cord injury populations. Dr. Shenoy Handiru's study combines transcranial electrical stimulation and wearable sensor-based exergaming to improve hand dexterity, while Dr. Einat Engel-Haber...

Growing number of states provide coverage for outpatient hemodialysis for undocumented immigrants

A growing number of states have implemented policies to cover outpatient hemodialysis for undocumented immigrants with kidney failure. This expansion may be due to increased awareness of poor outcomes with emergency hemodialysis and advocacy efforts. The move towards covering dialysis in all 50 states is called for by experts, who also...

SourceAmerican College of Physicians·JournalAnnals of Internal Medicine·TypeData/statistical analysis·DateApr 24, 2023

Electronic implant reactivates spinal-cord nerves of a patient with neurodegenerative disease

A groundbreaking system implanted directly on the spinal cord has restored blood pressure regulation in a patient with multiple system atrophy-parkinsonian type (MSA-P), enabling them to walk again after being bedridden for over a year. This innovative therapy paves the way for new clinical breakthroughs in treating degenerative diseases.

SourceEcole Polytechnique Fédérale de Lausanne·JournalNew England Journal of Medicine·TypeRandomized controlled/clinical trial·DateApr 6, 2022

Feeling dizzy when you stand up? Simple muscle techniques can effectively manage symptoms of initial orthostatic hypotension

Researchers discovered two simple physical maneuvers to effectively reduce blood pressure drops and alleviate symptoms of IOH in young women. Lower body muscle preactivation (thighs) and tensing improved cardiac output and stroke volume, respectively, leading to a reduction in symptoms upon standing.

SourceElsevier·JournalHeart Rhythm·TypeExperimental study·DateFeb 9, 2022

Practices related to fluid volume that are important for dialysis patients' health

Regular and careful assessment of target weight and fluid balance is crucial for dialysis patients' health and survival. The study highlights the importance of protocols that specify dry weight assessments and routine postural blood pressure measurements to lower all-cause and cardiovascular deaths.

SourceAmerican Society of Nephrology·JournalClinical Journal of the American Society of Nephrology·DateFeb 5, 2019

How low is too low? Study highlights serious risks for intensive blood pressure control

A Kaiser Permanente study found that patients with hypertension who experience unusually low blood pressures are twice as likely to experience a fall or faint. The study suggests that physicians should weigh the risks and benefits of aggressive blood pressure lowering on an individual basis, especially in older patients.

SourceKaiser Permanente·JournalAmerican Journal of Preventive Medicine·DateAug 24, 2018

Increase in heart rate as blood pressure falls could be early sign of neurological disease

Researchers discovered a simple bedside test that can diagnose neurodegenerative brain diseases, including Parkinson's and Lewy Body dementia. The test measures changes in blood pressure and heart rate after standing up, providing clues for healthcare providers to identify potential patients with synucleinopathies.

Epidural stimulation shown to normalize blood pressure following spinal cord injury

Researchers at University of Louisville have found that epidural stimulation can safely and effectively elevate blood pressure in individuals with severe spinal cord injury. The study, published in Frontiers in Human Neuroscience, included four research participants who experienced significant improvements in blood pressure regulation.

SourceUniversity of Louisville·JournalFrontiers in Human Neuroscience·DateMar 19, 2018

Pulse rate monitoring before a C-section can improve maternal health

A new study suggests that tracking pulse rate can help determine whether a woman needs blood pressure regulating medication after a spinal block before a Caesarean section. The research recommends considering factors such as pulse rate variability, pulse transit time, and body mass index to identify patients at risk of hypotension.

SourceSpringer·JournalAnnals of Biomedical Engineering·DateJul 11, 2017