Articles tagged with Influenza
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
The study identified 97 potential therapeutic targets for SFJD, with 27 key targets involved in antiviral, anti-inflammatory, and immune regulation effects. Molecular docking results showed strong interactions between core active ingredients and these targets.
Researchers are creating microphysiological systems to simulate infection and treatment in vitro, linking human lung and brain tissue models. This project aims to explore the relationship between respiratory diseases and neurological symptoms, potentially leading to new treatments.
Researchers will showcase results of a randomized clinical trial demonstrating Biovanta's efficacy in reducing common cold symptoms by strengthening the respiratory barrier and controlling inflammation. The presentation will also include preclinical data on antiviral formulas targeting rhinovirus and influenza.
A Spanish study found that the influenza vaccination campaign for children aged 6-59 months was effective in preventing acute respiratory infections and hospitalization. The study estimated the vaccine to be 70% effective against any influenza type and 77% effective against severe cases.
New research suggests that exposure to vape and e-cigarette residue on surfaces during pregnancy can cause immune system damage in unborn babies. The study found that maternal third-hand exposure to e-vapour results in significant, long-lasting effects on lung and bone marrow immune cell responses.
A cohort study found a significant association between maternal influenza infection during pregnancy and an increased risk of childhood seizures. The study suggests that maternal influenza may affect childhood neurological development, particularly for febrile seizures, but not epilepsy.
Researchers developed artificial lymphoid organ-chips to recreate human immune system's response to booster vaccines. The technology could potentially be used to evaluate the likely effectiveness of new protein and mRNA-based booster vaccines for COVID-19 and other infectious diseases.
A recent study published in Clinical Infectious Diseases found that high-dose and adjuvanted flu vaccines provided better protection against flu symptoms and hospitalization for people 65 years and older during the 2022-2023 flu season. The study included nearly half a million participants and showed significant advantages of these vac...
A team of researchers, led by Jason Shoemaker, are studying the effects of hormones on the immune system's response to the flu. Their goal is to develop targeted therapies based on a person's sex or hormone levels. The study aims to identify the molecules or pathways that affect the cells and begin to develop personalized treatments.
A novel two-step vaccination strategy has been developed to combat seasonal flu, pairing an intramuscular injection with a nasal spray of a weakened live-virus. The approach resulted in a strong immune response and reduced shedding of the vaccine candidate from the upper respiratory tract.
A new study by Emory University researchers found that increased ventilation in childcare settings may not be effective in preventing flu virus spread. The team used a play-based model using ferrets to study the spread of flu viruses in a setting that closely mimics a childcare venue.
Researchers at the University of Houston have developed two nasal sprays, NanoSTING and NanoSTING-SN, to prevent respiratory virus transmission. NanoSTING is an immune activator that can protect against multiple viruses, while NanoSTING-SN is a pan-coronavirus vaccine that can prevent transmission to unvaccinated individuals.
A new study reveals that blowflies in southern Japan are carrying the bird flu virus, which could lead to transmission through contaminated surfaces, food sources, and water. This finding highlights the need for effective countermeasures to prevent and control the disease in poultry farms.
Researchers found post-COVID conditions in primary care comparable to flu-like illnesses and lower than subspecialty and hospital settings. The study analyzed data from a national primary care registry and identified breathing difficulties, fatigue, sleep disturbances, and type 2 diabetes as common long-term health problems.
A recent study by Iowa State University researchers found that dairy cows have rich supplies of sialic acid, a sugar molecule that acts as a receptor for influenza. This discovery sheds light on how the virus attaches to hosts and raises questions about the risks of consuming raw milk from infected cows.
Researchers identified six priority pathogens for WWS during the Paris 2024 Games, including poliovirus, influenza A virus, and SARS-CoV-2. The study offers a model framework for context-specific WWS targets in mass gatherings.
Researchers tested hundreds of milk products from dozens of states and found no infectious H5N1 virus, but detected viral genetic material in 20% of samples.
A world-first study found that low-dose aspirin can create better blood flow to the placenta during pregnancy, potentially preventing complications caused by flu infections. The research also showed that mice treated with low-dose aspirin had improved fetal development and offspring survival.
Researchers found that H5N1 virus particles in unpasteurized milk can remain stable on metal and rubber components of commercial milking equipment for over an hour. This increases the potential for bird flu exposure among dairy farm workers and animal-to-animal transmission.
A new mathematical model suggests that waiting two days after symptoms arise for rapid COVID tests can increase accuracy by reducing false negatives. The model also recommends a 'test-to-exit' strategy to prevent infections and minimize inconvenience, which may be more effective than the five-day isolation policy.
A new study reveals that 96% of VA hospitals and 74% of non-federal hospitals mandate influenza vaccination or waivers for staff. This surge is largely attributed to the 2020 Veterans Health Administration directive. The increased mandates aim to reduce flu transmission among patients, as health systems strive to improve patient safety.
Scientists at Scripps Research have developed a potential drug-like molecule that blocks the first stage of type A influenza infection. The inhibitors target hemagglutinin, a protein on the surface of type A influenza viruses, and have shown improved cellular antiviral potency compared to previous compounds.
A study published in JAMA found that hospitalization for COVID-19 increased the risk of death more than seasonal influenza during the fall-winter 2023-2024 season. The research also highlights the importance of vaccination and public health measures to mitigate COVID-19-related mortality.
Researchers at Duke University have developed a new vaccine strategy that targets the portion of the flu virus surface with less variability, aiming for universal and long-lasting protection. The experimental vaccine elicits an immune response focused on the stalk region, which remains consistent despite viral mutations.
Researchers at University of Florida discovered a Florida bottlenose dolphin infected with highly pathogenic avian influenza virus (HPAIV), the first reported case in a mammal in North America. The team analyzed tissue samples and confirmed the presence of HPAI A(H5N1) virus subtype 2.3.4.4b.
Researchers at UC Riverside demonstrate a new vaccine strategy targeting a common viral genome part, eliminating the need for annual booster shots. The vaccine uses small RNA molecules to boost the immune system, making it safe for babies and those with weakened immunity.
A newly developed compound called UH15-38 has been shown to safely and efficiently block necroptosis, a key receptor in lung cells causing excessive inflammation and lung damage. The study demonstrates that UH15-38 can prevent influenza deaths even when administered late in the course of an infection.
Researchers found a 32% vaccine uptake among patients asked about receiving the flu shot and a 41% uptake for those who received a pamphlet, watched a video, and were told about benefits. The study suggests a systematic approach to increase vaccine uptake among underserved populations.
A new multitasking substance has been identified to prevent and treat both flu and COVID-19 infections concurrently. The long-acting recombinant cytokine protein rhIL-7-hyFc demonstrated therapeutic and preventive effects against various respiratory diseases, including COVID-19, influenza virus, and respiratory syncytial virus.
A recent study found that digital reminders for flu vaccination increased vaccination rates among older adults in Denmark by one percentage point. However, it did not improve clinical outcomes, including hospitalization and death rates.
Researchers at McGill University Health Centre discovered that a century-old BCG vaccine can provide cross-protection against influenza A virus and COVID-19 by inducing trained immunity. The study's findings have significant implications for developing vaccines against emerging respiratory viruses.
A large-scale study published in the BMJ found that children born in October are most likely to be vaccinated and least likely to be diagnosed with influenza, confirming public health guidance of getting flu vaccinations in October. The study analyzed over 800,000 children's health records from 2011-2018.
A US study published in The BMJ found that children born in October are less likely to get the flu and more likely to be vaccinated. The study suggests that October is the optimal time for young children to receive an annual flu shot, aligning with current recommendations.
Researchers have identified macrophages, immune cells that gobble up foreign substances, in the pleural cavity around the lungs. These cells play a crucial role in reducing inflammation and disease during flu infections.
Despite pandemic disruptions, emergency visits, hospital admissions, and intensive care unit stays were lower for children. However, there were delays in new diagnoses of cancer and diabetes, and an increase in diabetic ketoacidosis among children with diabetes. Researchers urge education campaigns to improve future pandemic preparedness.
Researchers have identified a new strategy to combat the seasonal flu by targeting sialic acids in the upper respiratory tract of infants. Using desialylated neuraminidase enzymes, they reduced mouse-to-mouse transmission rates of influenza A by over half, suggesting potential benefits for preventing flu spread in children.
A new study from Washington University School of Medicine reveals that people hospitalized for seasonal influenza face increased risks of long-term health effects, including death, hospital readmission, and organ system problems. Long flu is more debilitating than initially thought, with patients experiencing health loss similar to tho...
Commercially available NPBI-based air purifiers significantly reduced airborne virus infectivity, eliminating up to 99.98% of COVID-19, flu and RSV viruses in real-world concentrations.
A new study reports that antiviral medications are largely underused in young children diagnosed with influenza, highlighting opportunities for improvement in prevention and treatment. The study found low rates of antiviral use across all age groups, including a significant disparity in geographic regions.
Scientists at the La Jolla Institute for Immunology have uncovered a group of T cells known as mucosal-associated invariant T (MAIT) cells. These cells can recognize the same markers whether they come from humans or mice, opening up new possibilities for treating infectious diseases and improving cancer immunotherapies. The study also ...
Novel vaccine candidates using Computationally Optimized Broadly Reactive Antigens (COBRAs) protect against multiple influenza B strains, including those from different lineages. These vaccines show long-lasting protection, potentially reducing the need for yearly updates.
New research from MIT found that germicidal UV lights can produce potentially harmful compounds in indoor spaces. The study suggests that the lights should be used with appropriate ventilation to minimize health risks. Researchers emphasize that the new UV lights are not a replacement for ventilation but rather a complement to it.
Research finds that immune cells in older adults are similar to those in newborns and children, but less effective at recognizing infected cells. The study, published in Nature Immunology, suggests that tailored vaccines and therapies could be developed for different age groups based on the unique characteristics of killer T cells.
A study of over 15,000 individuals with chronic kidney disease found that young age, Black race, and low education and income were linked to lower flu vaccine uptake. The study suggests that targeted vaccination efforts could improve uptake among those with kidney disease.
A Phase 1 trial of FluMos-v2 has begun at the NIH's Clinical Center, evaluating its safety and immune response. The vaccine aims to provide protection against multiple flu strains, with the potential for less frequent dosing than traditional seasonal vaccines.
Researchers at University of California - Riverside uncover COVID's Achilles heel - its dependence on key human proteins. By understanding how the virus interacts with human cells, a new class of antiviral medication may be developed to block replication and treatment.
Scientists have found that lung-resident memory B cells, critical for pulmonary immunity, require interferon-gamma produced by T follicular helper cells to differentiate. These long-lived immune cells migrate to the lungs from draining lymph nodes and lie in wait to react quickly to future infections.
Researchers found that certain immune cells were associated with increased protection from flu symptoms, while others were linked to susceptibility. The study's findings have implications for developing tailored vaccine platforms and improving public health strategies.
Researchers found that dietary AHR ligands from cruciferous vegetables, such as kale and broccoli, maintain a healthy barrier in the lungs and prevent infection. The study shows that AHR activity is essential for lung barrier integrity during viral infections.
Researchers found that the flu blocks lung liquid secretion, allowing staph to infect lungs. Treatment with a CFTR-activating drug like ivacaftor restores liquid secretion and protects against staph infection.
A new study reveals that patients hospitalized with COVID-19 had a higher in-hospital mortality and persisted at 30 days, 90 days, and 180 days after discharge. The risk of death was nearly twice that observed in those who were discharged alive from an influenza-related hospital admission.
A WVU study found that U.S. cities with new professional sports teams saw increased influenza mortality rates, with the NHL teams causing the largest increase. The researchers analyzed data from 122 cities and controlled for factors like population and temperature to find a significant correlation between team arrival and flu deaths.
Researchers found serious neuropsychiatric side effects occur in both treated and untreated children with flu. The study highlights the importance of understanding these events in young children and those with underlying conditions.
Scientists have discovered how the PA-X protein degrades host cell RNA while leaving the virus intact, enabling it to infiltrate and replicate within cells. The findings provide new insights into how influenza A viruses evade the immune system.
A multinational study identified immune resilience as a critical factor influencing life span, HIV/AIDS, flu, sepsis mortality, recurrent skin cancer, and COVID-19 mortality. Individuals with optimal levels of immune resilience were more likely to resist infections and recover from inflammatory stressors.
Researchers used a multiomics approach to analyze changes in transposable elements after influenza A virus infection, identifying transcription factors contributing to individual responses. The study provides insights into the variable severity of illness among individuals infected with the same virus.
Research found that meeting both recommended weekly physical activity targets was associated with a nearly half the risk of dying from flu or pneumonia as those who met neither. Meeting only the aerobic activity target was linked to a 36% lower risk, while muscle strengthening activities showed no significant difference.
A clinical trial has started enrolling volunteers to test the experimental H1ssF-3928 mRNA-LNP vaccine, developed by NIAID's Vaccine Research Center, for its safety and ability to induce an immune response. The trial aims to find an optimal dosage and compare it with a current seasonal flu vaccine.
A new immunotherapy treatment developed by UCF researchers uses targeted IL-2 to fight respiratory viral infections with improved outcomes in animal studies. The treatment promotes an antiviral inflammatory response and reduces bronchial inflammation.
A new study by Texas A&M University researchers shows that exposure to ultrafine particles during pregnancy enhances the risk for respiratory viral infections, including influenza. Pregnant women are already at increased risk for severe flu, and air pollution exacerbates this vulnerability.