Articles tagged with Ulcers
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Researchers discovered that poor sleep quality is a significant contributor to peptic ulcer relapse in older adults. Participants with improved sleep demonstrated lower rates of heart disease, diabetes, and excessive alcohol consumption compared to those with recurrent ulcers.
Researchers identified specific strains of Staphylococcus aureus associated with non-healing wounds, while another microbe Alcaligenes faecalis was linked to quicker healing. The study suggests monitoring wound microbes could help doctors develop new treatment strategies for impaired wound healing.
Researchers found that specific strains of Staphylococcus aureus delay healing and that some bacteria can even improve wound outcomes. Monitoring microbiomes may help doctors tailor treatments to enhance healing and prevent amputations.
A study by researchers at the University of York found that costly external NHS hospital inspections do not lead to improvements in quality of care. Rates of falls and pressure ulcers improved before inspections, but slowed afterwards. The authors suggest a less resource-intensive approach to reduce costs and burden on staff.
A large breakthrough has been made in understanding the genetic causes of mouth ulcers, identifying 97 genome regions linked to the condition. These findings hold promise for developing new treatments and drugs to prevent or heal mouth ulcers, which affect up to 25% of young adults.
A promising compound discovered by Swiss TPH researchers is highly effective against Buruli ulcer, both in vitro and in vivo. The study found that compound Q203 has an activity level exceeding the current most active antibiotic rifampicin, potentially leading to a shorter treatment regimen with fewer adverse side effects.
Researchers at Purdue University have developed a shoe insole that gradually releases oxygen to aid healing of diabetic foot ulcers. The insole can be customized to fit individual wound sites and is designed to improve mobility for patients with diabetes, who are at risk of losing toes or limbs if left untreated.
Researchers at Michigan Technological University are developing nitric oxide-laden bandages that adjust chemical release depending on cell conditions. The goal is to create a more nuanced way to recover wound function and reduce the healing time of diabetic foot ulcers.
A new study finds that hospitals' progress in reducing hospital-acquired pressure ulcers (HAPUs) is largely due to preventing less-costly and less-dangerous early-stage HAPUs. The study recommends better data tracking methods, including using the same approach as for infections, to adjust rates and penalties based on patients' underlyi...
A new study found significant disparities in the use of outpatient dermatology services among different ethnic groups and socioeconomic statuses. Patients with lower incomes and education levels were less likely to receive care, while those with higher incomes and education levels had better access to specialized services.
Researchers at UTA have patented a smart seat cushion that uses real-time pressure monitoring and automated pressure modulation capabilities to redistribute body weight and prevent painful ulcers. The same technology can be used to create adaptable prosthetic liners, improving comfort and reducing skin damage in amputees.
Scientists at the Salk Institute have developed a technique to directly convert cells in an open wound into new skin cells, promoting healing and countering the effects of aging. The approach, which relies on reprogramming cells to a stem-cell-like state, shows promising results in treating large ulcers and skin damage.
A new study from the University at Buffalo found that the presence of new or worsened bedsores is associated with lower quality outcomes for rehabilitation patients, including decreased functional independence and longer hospital stays. The study used data from nearly 500,000 Medicare patients discharged between 2013 and 2014.
A new light device has been developed by the University of Manchester and Salford Royal NHS Trust, showing an average 83% improvement rate in treating finger ulcers caused by systemic sclerosis. The therapy combines infrared, red, and ultraviolet light and can be administered at home, offering a potential game-changer for ulcer treatment.
The NHS treats over 2 million wounds annually at a cost of £5.3 billion. Professor Peter Vowden highlights the need for improved systems of care to reduce this burden.
A study found that drinking honey or Carafate can provide a physical barrier and neutralize tissue pH increase, reducing injury severity compared to common household liquids. Honey may be a protective intervention for managing button battery ingestion in both households and hospitals.
Treating leg ulcers within two weeks improves healing rates by 12% compared to standard treatment, with a success rate of 85.6%. Early intervention helps patients recover quicker and reduces the risk of complications such as amputation.
Acute aortic syndrome is a group of conditions that can be challenging to diagnose due to similar clinical manifestations. Intravascular ultrasound imaging has been found to be useful in discerning the different forms of acute aortic syndrome, including aortic intramural hematoma.
The NUS microfibre sensor measures vital signs, heart rate, and blood pressure in real-time, offering convenience and comfort for patients. It can also detect plaque buildup in blood vessels, potentially preventing organ failure or heart attacks.
Researchers found that supervised exercise accelerated ulcer healing time by 22 weeks compared to compression therapy alone. The study suggests benefits for patients with venous leg ulcers, including cost savings.
A recent study published by the University of Leeds reveals that diabetic foot ulcers have severe consequences, including limited mobility and increased risk of heart disease. The research found that more than half of patients with infected ulcers did not heal over a year, highlighting the need for close monitoring and timely treatment.
Researchers found that low-energy shock-wave therapy significantly reduced digital ulcers in scleroderma patients by stimulating growth factors and forming new blood vessels. The treatment also showed no serious adverse events during the study, making it a promising approach for managing refractory digital ulcers.
Researchers at Massachusetts General Hospital have found that mature B lymphocytes can greatly accelerate the healing of acute and chronic wounds in both healthy and diabetic skin. The treatment also improved tissue quality and reduced scarring. High numbers of a patient's B cells can be isolated through standard blood pheresis procedu...
A new study from Washington University School of Medicine links popular heartburn drugs to an increased risk of death, particularly among those using the medications for extended periods. The research found that users of proton pump inhibitors had a 25% higher risk of death compared to those taking H2 blockers.
Physicians' adherence to H. pylori guidelines is low, with only 58% checking for eradication after treatment. A higher proportion of physicians are treating patients after a positive test, but antibiotic resistance remains a concern.
Millions of people with diabetes are at risk of developing foot ulcers, which can lead to further complications like strokes and premature death. Focusing on ulcer remission is crucial in delaying these complications and improving patient outcomes.
Aarhus researchers identified the mechanism behind the acid pump, which pumps acid into the stomach. Replacing a key amino acid with arginine enables the pump to function like an electroneutral pump.
New research from Organogenesis Inc. reveals that Apligraf can convert chronic venous leg ulcers into acute, healing wounds by modulating inflammatory and growth factor signaling. This breakthrough study published in Science Translational Medicine provides valuable insights for researchers and clinicians treating chronic wounds.
A mathematical model by Carl Bergstrom and colleagues explores the effect of publication bias on fact canonization in science. The study found that lower publication rates for negative results increase the risk of false canonization, but suggest that publishing more negative results could help minimize this risk.
A recent study published in the International Wound Journal found that implementing evidence-based prevention and treatment for diabetic foot ulcers through Medicare could save Australia $2.7 billion over five years. Patients receiving best care also experience faster ulcer healing, fewer hospitalisations, and amputations.
Scientists have developed a technique to convert diabetic foot ulcer cells into induced pluripotent stem cells (iPSCs), which can be used to study new therapeutic approaches and develop disease models. This breakthrough has significant implications for the treatment of non-healing chronic wounds.
A study by researchers at Tufts University successfully reprograms cells from diabetic foot ulcers into pluripotent stem cells, which can be turned into various cell types important for wound healing. The findings provide a new target for treatment and may lead to the development of more effective therapies for non-healing wounds.
A study found an association between a specific genetic pathway and the development of mouth ulcers in SLE patients. The VEGF genetic pathway was significantly associated with mouth ulcers and antinuclear antibodies, offering new insights into disease mechanisms and potential treatment targets.
Macitentan, a medication for pulmonary arterial hypertension, does not reduce digital ulcers in patients with systemic sclerosis. Few new ulcers appeared regardless of treatment, suggesting no benefit in managing this common complication.
A five-year study found that patients with negative beliefs about their diabetic foot ulcers had a higher risk of death. The study, published in PLOS ONE, suggests that addressing these attitudes could improve survival rates for people with diabetic foot ulcers.
Research at the University of Illinois found that finer corn particle sizes increase energy derived from corn, allowing producers to reduce added fat without affecting growth performance or carcass characteristics. This enables producers to decrease feed costs.
Researchers from UTARI and Pitt are developing an automated seat cushion to prevent pressure ulcers in wheelchair users. The smart seat cushion technology includes real-time pressure monitoring and automated pressure modulation capabilities to alleviate pressure buildup and discomfort.
Research by University of Huddersfield experts highlights the need for nationwide improvements in staff knowledge and skills to prevent pressure ulcers. The team's findings suggest that a national education programme is necessary to promote patient health-related quality of life and reduce healthcare costs associated with pressure damage.
A clinical trial at the VA Medical Center in Gainesville is testing maggot therapy for veterans with chronic diabetic ulcers. The treatment, which involves sterilized maggots feasting on dead tissue, has shown promise in clearing out wounds and reducing bacterial infections.
Researchers from the University of Surrey have made a breakthrough discovery that the bacteria causing Buruli ulcer disease triggers a blood clot, similar to deep vein thrombosis. This finding suggests that anticoagulant medicines may be effective in treating the disease, leading to faster healing and fewer side effects.
Researchers have discovered that low-intensity ultrasound can stimulate and accelerate wound healing in individuals with chronic wounds, particularly those with diabetes or age-related circulatory issues. This breakthrough has the potential to save the NHS £3.1 billion annually and improve treatment outcomes for over 200,000 patients.
Researchers developed a computational model to predict pressure ulcer formation in individuals with spinal cord injuries. The model demonstrated that early anti-inflammatory measures were crucial in preventing ulcers.
A computational model predicts the development and progression of pressure ulcers in spinal cord injury patients. The model validated by virtual clinical trials shows that anti-inflammatory measures must be applied early to prevent ulcer formation.
Two new papers by St. Michael's Hospital researchers identified effective treatments for diabetic ulcers and pressure ulcers, as well as cost-effective interventions for complex wounds. The studies analyzed high-quality systematic reviews and cost-effectiveness analyses to provide clinicians and decision-makers with a guide towards tai...
Researchers developed a topical gene regulation technology that uses spherical nucleic acids (SNAs) to silence the gene that interferes with wound healing in diabetic animals. The treatment improved healing and blood circulation at the wound site, reducing recovery time by 50%.
A recent study by researchers at Vetmeduni Vienna found that stomach ulcers in cattle are primarily caused by stress, nutrition, and weather conditions. The bacterial diversity present in the stomachs of healthy and ulcerated animals was nearly identical, suggesting that bacteria play a minor role in the development of ulcers.
The Sugar app, developed at Worcester Polytechnic Institute, is entering a pilot clinical study to assess its effectiveness in managing diabetes. The app tracks blood sugar levels, weight, exercise, and wound care, providing patients with personalized messages and insights.
The American College of Physicians has released new guidelines for preventing and treating bedsores, recommending protein supplementation and hydrocolloid dressings to reduce wound size. Advanced static mattresses and overlays are also recommended for patients at increased risk, while alternating air mattresses and overlays are advised...
Researchers have found that local implants of autologous adipose tissue-derived cells resulted in significant pain reduction and healing within two to seven weeks for all patients with long-lasting, non-healing digital ulcers. The treatment showed promise as an alternative to traditional therapies.
Researchers have developed a safe and effective skin patch to deliver a drug that enhances the healing of diabetes-related ulcers. The patch has been shown to accelerate wound healing and prevent ulcer formation in mice, offering new hope for millions of people with diabetes.
A new drug delivered through a skin patch has shown promise in healing diabetic foot ulcers and preventing their recurrence. The drug increases the protein HIF-1α, which helps form new blood vessels needed for wound healing.
A study found that intermittent PPI therapy is non-inferior to continuous infusion, reducing costs and improving patient comfort. Researchers suggest adopting the new approach could lower healthcare costs while maintaining quality care.
Researchers develop a prototype of the world's first intelligent prosthetic liner to measure pressure and pulling forces at the interface between a patient's stump and prosthesis. The device aims to provide accurate measurements for optimal socket fit, reducing pain and discomfort for amputees.
The nucleus tractus solitarii (NTS) is involved in the protective mechanism of pre-moxibustion on gastric mucosa. Moxibustion pretreatment at the Zusanli point can protect against acute gastric mucosa injury, while NTS damage inhibits these responses.
A new tissue repair drug has been shown to improve healing rates for diabetic foot ulcers, reducing the risk of amputation. Patients treated with the drug were twice as likely to have their ulcers heal within eight weeks compared to those receiving a placebo.
Researchers at the University of Southern Denmark have developed a new, safer, and noninvasive diagnostic technique for stomach ulcers. The technique makes the ulcer-causing bacteria in the gut light up in fluorescent green, allowing doctors to detect ulcers instantly without taking tissue samples.
A Johns Hopkins systematic review of 66 research papers found most skin ulcer treatments are technically flawed, with weak evidence supporting some treatments over standard compression therapy. The review suggests a need for well-designed studies to compare current minimally invasive surgical interventions to gold standard care.
A new study published in The Lancet has found that compression stockings are a cost-effective treatment for venous leg ulcers, reducing recurrence and nurse visits. While some patients may not prefer to wear the stockings, they offer improved value for money for the NHS compared to traditional bandages.
A recent UTHealth study found that nursing homes using high-density foam mattresses may not need to turn residents every two hours to prevent pressure ulcers. The study showed no difference in pressure ulcer incidence for residents turned at intervals of two, three, or four hours.
A new University of Michigan study found that Medicare's data source for reporting rates of pressure ulcers is not accurate for comparing hospital quality. The study revealed drastic differences in performance depending on the type of data used.