Articles tagged with Pregnancy
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A recent study developed a highly accurate risk prediction framework for preterm birth using genomics, transcriptomics, and large language models. The model achieved an AUC of nearly 90%, making it the most powerful approach in predicting preterm birth.
A large-scale study published in PLOS Medicine found no association between early life antibiotic exposure and the development of autoimmune diseases in children. Researchers analyzed data from over 4 million Korean children and discovered no increased risk of Type 1 diabetes, Juvenile idiopathic arthritis, or other autoimmune conditions.
A new study from Columbia University Mailman School of Public Health finds that punitive laws are largely ineffective and may actually harm those they aim to protect. Prosocial laws, on the other hand, prioritize access to care and harm reduction, recognizing the complex nature of substance use.
Researchers found a strong correlation between industrial pollution exposure during pregnancy and the risk of intellectual disabilities in grandchildren. A study using Utah Population Database data revealed that grandmothers' prenatal exposures can increase the risk of intellectual disabilities in their grandchildren's children.
Researchers developed a first-trimester blood test that accurately predicts gestational diabetes risk, using just seven biomarkers. The test's strong ability to distinguish high-risk from low-risk pregnancies could enable early interventions and reduce long-term health burdens.
A pediatric investigation study reveals that male fetuses prioritize growth while female fetuses focus on placental development under gestational hypertension. The findings support the growth strategy hypothesis and suggest sex-specific differences in fetal responses to prenatal stressors.
A study found that expectant mothers are often left to navigate decisions on prenatal screening for Down syndrome without sufficient information or emotional support. The research highlights the need for a national pathway to support families and provide clear information about screenings.
A systematic review and meta-analysis found that weight loss interventions before IVF increased unassisted pregnancy rates, while the effect on live births was unclear. Weight loss interventions studied included low-energy diets, exercise programs, and pharmacotherapy.
Researchers discovered a strong association between pregnancy complications and an increased risk of early stroke. Preeclampsia, preterm birth, gestational diabetes, and stillbirth were among the most significant risks found in the study.
A new study by the Environmental influences on Child Health Outcomes (ECHO) Cohort suggests that higher vitamin D levels during pregnancy may be associated with better cognitive test scores in children. Children of Black mothers, in particular, showed strongest association between vitamin D and cognitive development.
A new study found that mothers living in resource-poor neighborhoods in Arizona were 20% more likely to develop gestational diabetes mellitus compared to those in less deprived areas. The study also highlighted the high incidence of GDM among Native Americans, who had a rate nearly double the overall population.
A new study found that heavy drinking among women with a high desire to avoid becoming pregnant increased their risk of undesired pregnancy by 50% compared to moderate or non-drinking levels. In contrast, cannabis use did not elevate the risk of undesired pregnancy.
The book examines antibiotic-induced reproductive toxicity, microbiome alterations, and emerging concerns around antibiotic resistance. It provides critical insights for clinicians, pharmacists, researchers, and students in reproductive medicine and pharmacology.
A large-scale study in China found that nearly one-quarter of pregnant women experience depressive symptoms, highlighting the need for effective preventive and management strategies. Socioeconomic factors and partner support play crucial roles in the development and risk reduction of antenatal depression.
Researchers discovered that immune cells called T cells are abundant in mammary glands during pregnancy and breastfeeding, with some relocating from the gut. This finding may help explain the benefits of breastfeeding and inform dietary decisions to enhance breast milk production and quality.
A survey of over 1,600 US adults found that most know the negative impacts of smoking and drinking during pregnancy, but uncertainty exists around vaccines and weight gain recommendations. The majority are unsure about recommended vaccines for pregnant individuals, with a notable drop in knowledge since last year.
A study found that family physicians are improving maternal health in rural areas, particularly in Texas, Iowa, Nebraska, and Kansas. Rural counties with only hospital obstetric services have higher rates of social deprivation and Black populations.
A study published in Neurology found that antiseizure drug use during pregnancy continues despite evidence of birth defect risks, with higher use among people with low resources. The safest drugs saw a 30% increase in exposure, while those with uncertain risks saw an increase over time.
A large-scale study found strong links between maternal infections and adverse outcomes in babies born in Australia's Northern Territory. Congenital syphilis tripled the risk of preterm birth, while gonorrhoea increased the risk of stillbirth. The study highlights the need for more changes in STI testing during pregnancy.
Researchers found a significant link between vaccination of pregnant women and a drop in newborns being admitted to hospital with a serious lung infection. The RSV vaccine offered a 72% reduction in hospital admissions, with mothers who received the jab before delivery having twice the protective effect.
A study found that using some older and newer antiseizure medications during pregnancy is linked to an increased risk of malformations at birth. The study suggests that medications like valproate, phenobarbital, and topiramate may be associated with a higher risk of birth defects compared to lamotrigine.
Researchers found pregnant women with arteriovenous malformations are more likely to experience ruptures than non-pregnant women. Hormonal shifts and increased blood demand exacerbate health issues during pregnancy, placing added strain on the brain.
An international study has shown that BrECADD preserves fertility significantly better than eBEACOPP without worsening recovery chances. After treatment, 95% of women and 86% of men had normal hormone levels, enabling more pregnancies and births.
Research finds nearly a third of UK maternal deaths between 2014 and 2022 were linked to children's social care services. Women with such involvement were at higher risk of dying from psychiatric causes, murder, and mental health-related issues.
A comprehensive study protocol has been developed to investigate pregnancy-related stroke risk factors and long-term implications for mothers and their children. The nationwide multicenter study aims to identify key risk factors associated with ASPP and assess its impact on offspring.
Researchers found significant differences in gut microbiota composition between pregnant women with and without gestational diabetes. A diagnostic model based on genus-level markers showed high precision for early detection of the condition, offering new opportunities for prevention and personalized management.
A study published in the Journal of Epidemiology & Community Health found that a pro-inflammatory diet during pregnancy may raise a child's risk of developing type 1 diabetes. The research, which followed pregnant women from Denmark, found a 16% increase in risk for each unit increase in dietary measure of inflammatory food intake.
Pregnancy rates remained stable for IVF and IUI cycles in 2022, while single embryo transfer usage increased. Clinical pregnancy rates were stable, with singleton delivery rates improving to 91.5%. The use of ART rose by 15.6% despite a slight decline in total treatment cycles.
A recent study found that women with polycystic ovary syndrome (PCOS) have embryos carrying a unique 'epigenetic memory' that could explain why the condition often runs in families. Treating affected embryos with certain inhibitors showed promise in restoring normal gene activity, suggesting a potential therapeutic avenue.
A new international study reveals that male partners over 45 carry significantly increased miscarriage risks and lower live birth rates even when young donor eggs are used. The study found that older paternal age is linked to genetic mutations, sperm DNA fragmentation, and epigenetic changes, impairing embryo development.
A new study shows that a simple blood test taken in the first trimester of pregnancy can accurately identify women at risk of developing preeclampsia five months before clinical diagnosis. The test uses cell-free RNA, or cfRNA, to capture subtle molecular signals from multiple maternal tissues.
A new study reveals that women with polycystic ovary syndrome (PCOS) have a sharp reduction in the beneficial gut bacterium Parabacteroides merdae, alongside elevated levels of branched-chain amino acids. These changes may impair endometrial health and reproductive complications in women with PCOS.
Researchers uncover a key piece to the miscarriage puzzle, tracing risk back to a problem with the womb lining before pregnancy. The decidual reaction, which prepares the womb lining for pregnancy each month, often doesn't progress properly in women with a history of miscarriage.
A new study by researchers at UC San Francisco found that state bans on abortion led to significant increases in travel time, costs, and delays in receiving care. The study, which surveyed 855 people from states with abortion bans, revealed a 17% increase in second-trimester abortions and a 11.3-hour increase in travel time.
The American Medical Association (AMA) emphasizes the importance of COVID-19 vaccination during pregnancy, citing benefits and risks. Physicians should counsel patients on vaccine safety, considering individual factors and potential risks.
A large global study found that women who experience severe bleeding after childbirth face an increased risk of cardiovascular conditions, including heart failure and ischemic heart disease, for up to 15 years. The study analyzed data from over 9.7 million women across Europe, North America, and Asia.
Researchers found an increased risk of stroke in women who experienced diabetes, high blood pressure, preterm delivery, or low birth weight during pregnancy. These complications could act as early signals for cardiovascular problems, enabling women to receive help and reduce their risk.
Children of older mothers are more likely to be born prematurely or with complications. The study found that babies born to mothers 45 years and older had the highest risks of stillbirth, premature birth, and low birth weight compared to younger mothers.
Mortality from slow fetal growth and malnutrition has increased nearly 2% annually, potentially linked to impaired prenatal nutrition. Medical advancements, improved prenatal care, and neonatal intensive care interventions may have contributed to the overall decline in U.S. neonatal mortality.
Elevated cortisol levels in preterm fetuses disrupt normal heart development, potentially leading to increased cardiovascular disease risk. Cortisol exposure accelerates heart development in ways that may not be beneficial, ultimately compromising heart health.
Researchers found associations between influenza A infection, disrupted gut and nasal microbiomes, and detrimental changes in hippocampal gene expression. Maternal vaccination during pregnancy appeared to offer protection from these changes.
A recent USC study found associations between increased exposure to wildfire smoke and heat stress during preconception and the first trimester with the odds of having a small-for-gestational-age infant. Living in a climate-vulnerable neighborhood can increase these risks, particularly for women exposed to heat stress.
A UC Riverside study found that Toxoplasma gondii can significantly disrupt brain function by interfering with communication between brain cells. Infected neurons release fewer extracellular vesicles, which can lead to seizures, neural damage, or altered brain connectivity.
A community-based mentoring scheme in Sierra Leone has been found to save lives and help girls return to education, doubling survival rates. The pilot trial reduced maternal and perinatal deaths by almost half, with one baby's life saved for every 18 mentored girls.
A recent study published in Heredity investigated whether female odour-based mating preferences can predict gamete-level compatibility in humans. Women preferred the body odours of MHC-similar men, but sperm from MHC-dissimilar men exhibited higher motility when exposed to female follicular fluid.
Pregnant individuals are at high risk of measles infection and its complications. Experts emphasize the need for urgent access to IVIG and updated hospital protocols to protect vulnerable groups.
A study reveals that pre-eclampsia increases the risk of developing severe cerebrovascular complications, including stroke, after childbirth. The researchers found that a history of PE impairs collateral recruitment and worsens ischemic stroke outcomes due to increased sensitivity to cerebral ischemia and elevated oxidative stress.
A new study finds pregnant women in abortion-ban states have worse access to routine medical care and pregnancy coverage due to skimpy Medicaid programs. The researchers identified three Medicaid policies driving this disparity, highlighting the need for Congress to expand coverage and ensure all women can get needed care.
A study found that between 11.6% and 20.2% of women with a history of pregnancy or testing for pregnancy visited crisis pregnancy centers across four US states, including Arizona and New Jersey. The attendance rates were not correlated with age, race, or socioeconomic status.
A new NIH grant will aid researchers at Wayne State University in studying the effects of fentanyl during pregnancy. The two-year study aims to determine the impact of gestational fentanyl exposure on morbidity and mortality, developmental milestones, and brain development in offspring.
A University of Otago study found that prolactin helps regulate core body temperature during pregnancy, reducing the risk of hyperthermia. This adaptation promotes a safe environment for the fetus and enhances maternal survival and wellbeing.
Children born to mothers with a BMI of 35 or higher are at heightened risk of being admitted to hospital for an infection. Maternal obesity is characterised by chronic inflammation, which increases the risk of a disordered immune system response and unfavourable changes to the gut microbiome.
A new University of Minnesota report shows a continued 30-year decline in MN teen birth rates, with lower chlamydia rates than in decades. The report also emphasizes the importance of addressing social determinants of health and providing accurate sexual health information to all youth.
A recent study found that cannabis use during pregnancy can alter DNA methylation in placental tissue, which may impact child behavioral outcomes. The research, conducted by Dr. Emma C. Johnson, suggests a potential link between prenatal cannabis exposure and gene regulation in the developing fetus.
First-time mothers experience significant sleep loss and disruption in the weeks following childbirth, with average daily sleep duration decreasing to 4.4 hours. The study reveals that this unique type of sleep disruption persists throughout the first months of motherhood, affecting new mothers' quality of life.
A new study published by the American Academy of Neurology found no increase in neurodevelopmental disorders such as autism and ADHD in children whose mothers took triptan medications before or during pregnancy. Researchers analyzed data from over 26,000 pregnancies and followed the children for an average of eight years.
A recent study published in PLOS ONE found that higher maternal selenium levels during pregnancy are associated with a lower risk of streptococcal infections in children. The research tracked over 74,000 mothers and their children to explore potential links between maternal metal exposure and infection risk.
A recent survey found that over 83% of Americans believe the benefits of the MMR vaccine for children outweigh the risks, despite a current measles outbreak. The survey also showed that vaccination rates are dropping and many people lack knowledge about measles symptoms and prevention.
Researchers found that inflammation in the female reproductive tract can hinder fertility, but replenishing progesterone levels can help. This discovery could improve women's chances of becoming pregnant and save more pregnancies.
A UC San Francisco-led study found that delivering medicine for spinal muscular atrophy (SMA) via the amniotic fluid was safe and helped prevent damage to nerve cells. The therapy used molecules called antisense oligonucleotides (ASOs), which can alter gene expression, and was tested in mice and sheep with promising results.