Articles tagged with Cancer Patients
The ASTRO's 2025 Annual Meeting will feature pivotal studies in radiation medicine, highlighting advances in radiopharmaceutical therapy and new indications for low-dose radiation therapy. The meeting will also explore cutting-edge techniques for prostate, breast, lung, and other common cancers.
A new UCLA-led study finds that government housing assistance reduces the risk of medical bill stress by nearly seven percentage points among US renters with cancer, leading to improved quality of life and reduced poor physical and mental health outcomes.
A recent study published in CANCER reveals that many patients with advanced cancer report receiving treatment that focuses on longevity rather than comfort. Despite this mismatch, the treatment did not appear to extend life for those who did not want it. The research highlights the importance of open conversations between doctors and p...
Researchers envision AI-powered systems that identify patients at risk of mental health struggles, provide continuous psychological monitoring and tailor interventions. AI can also overcome barriers to mental health care by delivering support exactly where and when it's needed, including rural areas.
A new study from the University of Missouri-Columbia highlights the importance of consistent primary care coordination in cancer survivorship care. The research found that only a third of patients consistently saw the same primary care clinician during and after cancer treatment, leading to fragmented care and gaps in patient services.
Researchers found that decompression with a nasogastric tube is linked to reduced complications in patients after oesophageal cancer surgery. This challenges declining trend of abandoning the tube post-surgery, which was previously thought to be safe.
A new survey conducted by Ohio State University Wexner Medical Center highlights the widespread emotional impact of cancer on adults when a loved one is diagnosed. Cancer anxiety can significantly impact long-term survival, with up to five times the likelihood of depression among cancer patients compared to the general population. The ...
A new treatment approach using cyclophosphamide has been found to prevent most graft-versus-host disease in mismatched transplants. The study shows that 80% of patients are alive after a year, similar to outcomes seen in fully matched transplants.
A study of 62,839 people diagnosed with non-metastatic prostate cancer in Sweden found that those treated according to NCCN Guidelines were likely to survive their cancer for their remaining life-expectancy. Those with low- and intermediate-risk cancer were six times more likely to die of other causes than prostate cancer.
Researchers have identified a hidden molecular mechanism involving two proteins that allows tumors to resist treatment. A new gelatin-based nanoparticle has been developed to shut down both proteins simultaneously, showing promising results in early studies with mice.
A study of 168,547 postmenopausal women found that excess weight is associated with a 31% higher risk of breast cancer in those with cardiovascular disease. Higher BMI also increases the risk in women without cardiovascular disease, although to a lesser extent.
The new NCCN Guidelines Navigator tool offers an interactive platform for accessing evidence-based guidelines, facilitating easier searching and navigation. The initiative aims to improve patient care and outcomes by providing healthcare professionals with up-to-date recommendations.
Experts from the National Comprehensive Cancer Network (NCCN) and African Cancer Coalition gathered in Nairobi, Kenya to update NCCN Clinical Practice Guidelines in Oncology for Sub-Saharan Africa. The meeting aimed to improve cancer care in the region by sharing evidence-based recommendations.
Researchers found that it took 13 years for cervical cancer screenings to halve among women over 65, and even longer for prostate cancer screenings to decrease significantly. The study emphasizes the need for more effective tracking mechanisms to identify and reduce inappropriate screening practices.
The ESMO Gynaecological Cancers Congress 2025 will convene in Vienna, Austria, from June 19-21, featuring novel data on immunotherapy combinations and emerging treatment strategies for rare gynaecological cancers. The congress will also explore innovative approaches using antibody-drug conjugates.
Recent advances in tissue-agnostic cancer drugs have resulted in highly effective treatments, but few are approved for children. Oncologists argue that these drugs should be licensed for all ages due to their effectiveness and fewer side effects. The researchers suggest that age-agnostic approvals could be made through analyzing electr...
Researchers found that childhood kidney cancers have significantly more genetic changes than previously thought, with some tumors having up to millions of changes. This discovery challenges the existing notion that childhood cancers have few genetic variants and suggests new treatment options such as immunotherapy.
The University of Houston has launched a $3M Cancer Immunotherapy Biomarker Core to accelerate early diagnosis and treatment response in cancer. The core will offer comprehensive targeted proteomic cancer biomarker screens, enabling researchers to identify better biomarkers for cancer.
A randomized controlled trial found that additional imaging techniques such as fast MRI and contrast mammography can detect early-stage cancers in women with dense breasts that were missed by mammograms. The study showed a cancer detection rate of 1.7% for fast MRI and 1.9% for contrast mammography, compared to 0.4% for ultrasound.
A new study published in Blood Cancer Discovery found that certain gene mutations and the maturity of leukemia cells affect how patients respond to venetoclax and hypomethylating agents. Researchers identified a subtype of acute myeloid leukemia with worse outcomes, particularly those without the NPM1 mutation.
The American Society for Radiation Oncology (ASTRO) will host its 67th Annual Meeting in San Francisco from September 27 to October 1, 2025. The meeting will feature over 2,500 research presentations and posters on advances in radiation oncology and non-cancer indications.
Researchers identified changes in stromal tissue associated with increased aggressive breast cancer risk and poorer survival rates among women with benign breast disease. The study used machine learning to detect subtle changes in breast tissue samples from over 9,000 women.
A study published in The Lancet Regional Health – Europe found that patients with low household income were more likely to be diagnosed late and receive less effective treatment for liver cancer. This highlights the need for targeted screening in deprived areas to improve early diagnosis and survival rates.
A Phase III trial shows molecular profiling can safely reduce radiation for women with early-stage endometrial cancer, tailoring treatment to individual tumour characteristics. Nearly half of patients can be spared radiotherapy without compromising cancer control.
Pennington Biomedical welcomes Dr. Adithya Hari, MD, with expertise in nuclear oncology and translational science, strengthening cancer research and patient-centered innovation in Louisiana. He will establish a research program focused on nuclear medicine and dedicate time to direct patient care through a clinical partnership.
A new review advocates for building confidence in AI applications by implementing robust data governance frameworks, enhancing transparency, and involving stakeholders. The authors emphasize the importance of addressing ethical implications and ensuring equitable access to AI-driven innovations in clinical oncology.
Researchers at TUM developed an AI-powered algorithm to predict kidney damage in prostate cancer patients undergoing lutetium-177 PSMA therapy. Early detection could enable personalized treatment adjustments to prevent organ damage.
A new clinical study has treated its first patient with a novel therapy aimed at difficult-to-treat melanoma skin cancer tumors. The treatment uses modified immune-system T cells to target PRAME, a peptide found in many melanoma tumor cells.
AIC100 demonstrated encouraging responses and an acceptable safety profile in patients with two types of advanced thyroid cancer, including anaplastic thyroid cancer (ATC) and relapsed/refractory poorly differentiated thyroid cancer (PTDC). The therapy showed significant tumor shrinkage and disease control in 56% of patients.
A study found that most head-and-neck cancer survivors who underwent radiation don't know about survivorship care, despite grapple with side effects such as dry mouth, swallowing problems, and psychological distress. The survey also found that 40% of survivors still struggle with dry mouth and nearly a quarter reported trouble swallowing.
A randomized controlled trial demonstrates the feasibility and acceptability of integrating exercise and rehabilitation services into routine breast cancer care. The Comprehensive Oncology Rehabilitation and Exercise (CORE) program improved functional deficits, fitness, and strength in patients with stage I-III breast cancer.
Adaptive NK cells exhibit tumor-specific immune memory and cytotoxicity in ovarian cancer, making them promising for cancer treatment. The study challenges previous perceptions of NK cells, which have historically been considered only innate immune cells with no memory function against cancer.
A highly sensitive bone marrow test has shown to double survival rates for patients with AML mutations in NPM1 and FLT3 genes, allowing for early detection of potential relapse. This trial indicates that regular molecular testing can improve long-term survival rates by restarting treatment earlier.
A predictive model combining tumor marker readings with patients' genetic profiles enhances predictions for patient survival and surgery decision-making. The new tool accurately identifies candidates who would benefit from surgery, suggesting that current tumor marker evaluations are inadequate for these genetic profiles.
A novel topical BRAF inhibitor gel called LUT014 has been shown to significantly reduce the severity of an acne-like rash in patients undergoing anti-EGFR therapies for colorectal cancer. The treatment's safety and effectiveness have been confirmed, offering a potential solution to managing this common side effect.
The American Association for Cancer Research (AACR) will honor Senator Tammy Baldwin and Senator Shelley Moore Capito for their national leadership in advancing cancer prevention and treatment. The organization also recognizes Larry Saltzman, MD, a cancer survivor who has surpassed his expected lifespan due to NIH funding.
The treatment demonstrated early signals of efficacy, with 65.7% of patients experiencing lasting stable disease, and was generally well-tolerated, with most adverse events being mild and manageable.
A Phase II trial found durable antitumor activity in patients with BRCA1/2 mutations treated with olaparib and pembrolizumab, with 8.3% complete response rate
A new voluntary program, the Medicare Prescription Payment Plan (MPPP), could greatly reduce out-of-pocket costs for Medicare patients taking expensive oral cancer drugs. By spreading annual costs across 12 monthly payments, patients can avoid large upfront payments and make treatment more affordable.
Researchers have discovered genetic properties in prostate cancer that can be targeted to improve patient outcomes, particularly for Chinese men. The findings highlight the potential of precision medicine and more effective treatments.
Hyperbaric oxygen treatment has been shown to provide long-term relief for patients with late radiation-induced injuries, improving symptoms of urinary incontinence, bleeding, and severe pain. The treatment can lead to the healing of chronic injuries and allow patients to live a fully normal life.
A patient with adenoid cystic carcinoma was successfully treated with step-and-shoot proton arc therapy at Corewell Health William Beaumont University Hospital. The treatment showed minimal side effects, including only light skin discoloration, and the patient remains cancer-free.
Researchers developed an AI platform that tracks cancer biomarkers to personalize treatment dose adjustments for patients with advanced solid tumors. The study resulted in optimal doses being administered to 97.2% of patients, with average reductions of 20%.
Researchers at Tulane University identified a potential new way to treat idiopathic pulmonary fibrosis (IPF) using an FDA-approved cancer drug. The treatment works by blocking the CTLA4 protein, which blocks overactive T cells, allowing the immune system to clear out damaged cells that cause lung scarring.
The Colorectal Cancer Alliance is strengthening its commitment to Project Cure CRC, a nonprofit dedicated to ending the disease through innovative research and patient navigation. The organization has awarded three new grants and will present two poster sessions at the AACR Annual Meeting.
Researchers developed an AI algorithm based on the medical history of over half a million patients, enabling GPs to identify increased risk of lung cancer up to 4 months before diagnosis. This method may also offer early detection for other types of cancer and improved patient outcomes.
A study by Johns Hopkins Medicine found that older adults with cancer benefit equally from immunotherapy treatments as younger patients, with key differences in their immune responses and cells. Researchers hope to develop new therapies tailored to different age groups' needs and improve treatment success.
A survey of patients who underwent breast cancer screening mammograms found most support AI's role as a second reader, but concerns about data privacy and bias persisted. Demographic factors such as education and racial background played a significant role in shaping patient perceptions of AI.
Researchers from the UCLA Health Jonsson Comprehensive Cancer Center are presenting new findings on combination therapies for liver and pancreatic cancers, including a new organoid model for personalized head and neck cancer treatment. Additionally, they are discussing the potential of liquid biopsies for cancer detection and monitoring.
Researchers at MD Anderson Cancer Center have discovered that adding copper-loaded agents to radiotherapy can overcome radioresistance in preclinical models of thoracic cancer. A novel blood-based biomarker, OSMR, has also been identified in patients with acute myeloid leukemia (AML), which shows prognostic potential and can help ident...
A new combination therapy using cemiplimab and isatuximab has shown promising results in a phase 2 clinical trial for extranodal NK/T-cell lymphoma, with 51% of patients achieving complete response. The study validated genomic biomarkers and a prognostic model developed by the National Cancer Centre Singapore, offering potential for mo...
The Lung-MAP 3.0 trial introduces a simplified genomic screening process, allowing most patients to be matched to a targeted treatment sub-study based on prior testing results. This expansion increases access to investigational treatments for patients with advanced non-small cell lung cancer.
A new study found that a gene-based blood test can accurately predict skin cancer recurrence in stage III melanoma patients. The test measures circulating tumor DNA levels to identify those most likely to respond well to therapy.
The SNMMI Mars Shot Research Fund has awarded a $100,000 fellowship to Dr. Randy Ye for his research on FAPI PET imaging for detecting invasive lobular carcinoma. The study aims to assess the ability of FAPI PET and FDG PET to detect tumors and evaluate its impact on patient care.
A new inpatient onconephrology service has been established to care for patients with cancer and kidney disease, resulting in improved kidney recovery rates. The study found that patients treated by the dedicated service were more likely to have kidney recovery at discharge compared to those treated by general nephrology services.
University of Virginia researcher Natasha D. Sheybani has received a $5.5 million grant to advance her research on focused ultrasound technology for breast cancer immunotherapy. Her work aims to enhance the safety, effectiveness, and precision of immunotherapy drugs.
Researchers developed a saliva test that uses AI to identify genetic mutations in the DPYD gene, which can affect how well cancer patients respond to chemotherapy. The study found several new mutations that could lead to severe side effects from 5-fluorouracil, a widely used chemotherapy drug.
Researchers have shed light on how a new type of antibody treatment works against ovarian cancer by reactivating patients' immune cells. The study shows that MOv18 IgE reverses the suppression of immune cells and induces them to kill cancer cells, providing new insights into this therapy.
The Ontario Institute for Cancer Research (OICR) has launched a yearlong campaign showcasing the personal stories of cancer patients and researchers. The campaign aims to shine a spotlight on the community's achievements in cancer research. OICR brings together scientists, clinicians, and everyday Ontarians to solve cancer together.
Researchers at Cold Spring Harbor Laboratory have identified a connection between the brain and immune system responsible for cachexia-related apathy. By targeting specific neurons and immune system proteins, they hope to improve cancer patients' quality of life and tolerance for treatments.