Articles tagged with Developmental Stages
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
A cross-sectional study found that up to half of adolescents in the US were using generative AI apps, while a small subset engaged in heavy use. The study highlights the need for future research on individual differences in GenAI use and its impacts on adolescent development.
A cohort study of students in grades 4-12 found that social media use varied by age and sex, with heavy use linked to poorer well-being. The study's findings suggest that abstinence from social media may not always be beneficial for adolescents.
Dr. Maria Margarita Behrens' work deciphers the molecular signatures defining every human brain cell type, shedding light on neural development and psychiatric disorders. Her single-cell epigenomic atlases will enable researchers to target specific cell types with unprecedented precision.
Children exposed to high levels of screen time before age two showed changes in brain development linked to slower decision-making and increased anxiety by their teenage years. Parent-child reading may offer protection against these effects.
Research found that children exposed to higher-than-usual temperatures were less likely to meet developmental milestones for literacy and numeracy. The effects were more pronounced among economically disadvantaged households, with access to clean water and urban areas.
The ISSCR, SDB, and the Allen Institute are hosting a three-day scientific symposium featuring early-career scientists, focusing on cross-disciplinary exchange and amplifying emerging leaders in developmental biology and stem cell science. Confirmed topics include data analysis, model systems, spatial awareness, and cell fates.
Researchers have created detailed maps of the mammalian brain's developmental stages, shedding light on how brain cells form and mature. The findings provide valuable insights into the critical periods that may help diagnose and treat neurodevelopmental disorders such as autism and ADHD.
A new study from the University of Houston reveals that outdoor fun with a focus on challenge, novelty, and guidance can promote positive youth development. The 'Four Types of Fun' model offers a theoretical framework for understanding fun and its role in character building.
New research from the Stowers Institute for Medical Research reveals planarian stem cells ignore their nearest neighbors and respond to signals further away in the body. This discovery may help explain the flatworm's extraordinary ability to regenerate and offer clues for developing new ways to replace or repair tissues in humans.
A recent study published in Integrative and Comparative Biology found that bonnethead sharks' skin undergoes significant changes as they mature, with younger sharks having fewer ridges on their denticles. These changes likely improve swimming performance and protect the skin from predators or injuries.
A recent study published in Alcohol: Clinical & Experimental Research found that fathers' alcohol use may have a negative impact on children's growth and development by age seven. Children of fathers who drank heavily during pregnancy were more likely to be shorter, have smaller heads, and score lower on verbal IQ tests.
The NIH Baby Toolbox is a new nationally standardized assessment tool for infants aged 16-42 months, measuring cognitive, language, motor and social-emotional skill development. The tool uses video-based assessments to engage infants in tasks, overcoming previous limitations in measuring young children.
Researchers have established apple snails as a system to study eye regeneration, which may hold the key for restoring vision due to damage and disease. The team discovered that the snail eye is anatomically similar to humans and can regrow itself, with genes such as pax6 playing a crucial role in development.
Researchers at the Francis Crick Institute discovered that early heartbeats trigger biological signals guiding the formation of a functional beating heart in zebrafish. The study highlights the heart's ability to remodel and adapt, shedding light on congenital heart conditions.
US adolescents spend nearly an hour per school day on smartphones, with most of this time dedicated to social media. The study highlights developmental differences in smartphone use, with younger teens using less than older adolescents.
Researchers at King Abdullah University of Science and Technology (KAUST) have created a deep learning tool called deepBlastoid to study human embryo development in artificial laboratory conditions. The tool can evaluate images of blastoids equally well as expert scientists but 1000 times faster than traditional methods.
Dr. Xuyu Qian's pioneering research using MERFISH technology created an unprecedented developmental atlas of the human cerebral cortex, analyzing over 18 million single cells. His work aims to identify mechanisms disrupted in conditions like malformations and autism spectrum disorder.
A study by the CSIC-UMH Institute of Neurosciences uncovers how flies' flight stabilizers, the halteres, take shape. The structure is stabilized by a sophisticated cellular system that connects its two surfaces through an internal framework.
The use of GLP-1 receptor agonists among diabetes patients is associated with a higher risk of developing incident neovascular age-related macular degeneration. Further research is needed to understand the underlying mechanisms and trade-offs between benefits and risks.
Researchers created first complete genetic activity map of a branching worm, revealing how it controls reproduction across its multiple body branches. The study highlights the unique genetic toolkit and challenges understanding of animal bodies' organization.
A cross-sectional study found common experiences of gaslighting and substantial distress among patients with vulvovaginal disorders. The study emphasizes the need for education supporting a biopsychosocial approach to vulvovaginal pain, as well as the development of validated instruments to quantify patient experiences.
A study found that parental technology use in a child's presence was negatively associated with cognitive and psychosocial outcomes, as well as screen time among young children. The effect sizes were small, highlighting the need for further research on potential impacts on physical activity, sleep, and motor skills.
A new study reveals that maternal immune activation can alter hippocampal neuron excitability in newborn rats, with implications for neurodevelopmental disorders. Prenatal inflammation has been linked to conditions like autism, schizophrenia, and depression, and may underlie their increased risk.
The COVID-19 pandemic has been associated with negative developmental trends in kindergarteners, persisting beyond the pandemic's onset. The study highlights troubling trends in kindergarteners' development before and during the pandemic, underscoring the need for further research.
The Antarctic midge employs a unique survival mechanism by undergoing quiescence in its first year and obligate diapause in its second. This adaptation allows the insect to quickly resume development when temperatures rise.
Researchers have created a comprehensive atlas of zebrafish development, combining time-lapse videos and gene expression data to map the behavior of individual cells. This breakthrough tool offers new insights into how lifeforms develop from single cells to complex organisms.
A cohort study examines how traumatic and adverse childhood experiences influence developmental changes in psychiatric risk and cognitive ability. The findings suggest targeted early prevention and intervention strategies for at-risk youth.
Researchers investigate how racism affects development during childhood and adolescence, finding significant increases in epigenetic age acceleration. The study suggests that policies and social regularities may perpetuate discrimination against ethnically and racially minoritized adolescents.
Researchers at the University of Cambridge found that flowers like hibiscus use an invisible blueprint to dictate the size of their bullseyes, which can significantly impact their ability to attract pollinating bees. Larger bullseyes are preferred by bees and can potentially boost efficiency for both bees and blossoms.
Dartmouth anthropologists argue that jungle gyms and monkey bars are essential for childhood development, allowing children to build resilience and confidence through risk-taking play. The research cites fossil evidence showing early humans spent extensive time in trees, and modern nonhuman primates exhibit similar climbing skills.
Researchers at University of California - San Diego have discovered a link between environmentally induced autism and altered neurotransmitter expression in the brain. The study suggests that manipulating these neurotransmitters early in development can prevent autistic-like behaviors.
Scientists developed a framework that aligns satellite data with rice growth stages to boost paddy rice mapping accuracy. The new approach improved accuracy by 6.44-16.10% and provided insights into critical factors influencing rice phenology and spatial distribution.
A study of 1,300 emerging adolescents found that higher parental technoference levels were associated with increased anxiety symptoms, inattention, and hyperactivity. The findings highlight the need for parents and emerging adolescents to discuss digital technology use and mental health as part of routine care.
A WVU biologist is studying how genes establish animal body plans and contribute to regenerative abilities. He has identified Hox genes as key players in planarian regeneration, suggesting their functions may differ in highly regenerative versus poorly regenerative organisms.
Researchers at University of Tsukuba have achieved the first successful lab rearing of Hypselodoris festiva, revealing a previously unknown growth process. The study describes nine stages of development, from metamorphosis to adulthood, and provides a reference for further research on Chromodorididae species.
A groundbreaking approach inspired by bio-inspired neuromorphic imaging and speckle correlography has unveiled a revolutionary technique for optical image encryption. This method leverages computational neuromorphic imaging to encrypt images into event-stream ciphertexts, significantly enhancing security and complexity.
Researchers have created a detailed 3D atlas of the African clawed frog's development, revealing key changes during metamorphosis. The atlas uses X-ray microtomography to show the transformation from tadpole to mature adult frog.
A study found that individuals with stable employment have better identity synthesis and experience less identity confusion compared to those with unstable employment. Those with higher identity synthesis also report higher life satisfaction regardless of employment status.
A new biomarker has been discovered that can help predict which patients with clear cell renal cancer are at higher risk of recurrence. The 15-gene signature was found to be independently associated with worse disease-free survival and disease-specific survival in two large validation datasets.
The number of US individuals with chronic hypertension in pregnancy increased significantly, while medication treatment remained low, according to a new study. The findings highlight the need for improved maternal health strategies to address high blood pressure and cardiovascular complications.
Researchers discovered that killifish early embryogenesis differs from other fish species, with the embryo's body axis formed through self-organization rather than maternal pre-patterning. This adaptation allows the species to survive dry periods without accumulating damaged cells.
Researchers found that restricting screens in bedrooms and at mealtimes has the biggest impact on reducing screen time and addictive behavior. Parents who model healthy practices at home also see a decrease in their child's screen use. Limiting and monitoring screen time can reduce usage by 1.29 hours and 0.83 hours, respectively.
A novel approach to training AI systems uses information about spatial position to identify objects and navigate surroundings, inspired by children's visual development. The method improves contrastive learning models' effectiveness by incorporating simulated spatial context information, outperforming base models in various tasks.
A study of Neanderthal and Palaeolithic human teeth reveals that the two species experienced childhood stress at different developmental stages. Neanderthal children faced increased stress post-weaning, while Palaeolithic humans were less stressed after weaning.
Researchers used supercomputers to study how fruit fly embryo cells develop into wings, offering a window into human development and possible treatments for birth defects. The team found that actomyosin drives much of the development process, particularly in the lower wing disc flattening.
A new study published in Stem Cell Reports has identified the key player in coordinating early mouse embryo development, revealing the importance of NKX1-2 protein. The protein ensures that genetic instructions are executed correctly and at the right times, managing cell machinery production and chromosome organization.
A study of 50,000 US children found modest decreases in developmental screening scores, sparking cautious optimism and concern for long-term implications. Continued surveillance is crucial to understand the population-level effects of the pandemic on child development.
Researchers suggest a follow-up colonoscopy within defined periods after abnormal stool-based screening test results. The proposed measure aims to address low current performance rates and produce reliable results.
Researchers at University of Arizona have developed a novel approach to combat mosquito-borne diseases by targeting the unique alkaline environment of larval mosquito guts. The study uses specially designed chemical compounds to modify proteins, hindering food digestion and growth.
Researchers found associations between prenatal vitamin and metal exposures and epigenetic aging biomarkers in early life. A one standard deviation increase in essential metals was associated with lower Horvath EAA at birth, while arsenic was linked to greater EAA at birth and in childhood.
Researchers developed a novel machine learning-based approach to analyze diffuse reflectance spectroscopy data, achieving higher accuracies and speeds than existing methods. The 'wavelength-independent regressor' model overcomes use-error limitations by incorporating diverse datasets, making it suitable for clinical settings.
A new study highlights the wide range of urban exposures during early childhood that can influence growth and development, including air and noise pollution, overcrowding, and limited green space. The first 2000 days of life are a critical period for physical, cognitive, social, and emotional health outcomes.
Researchers found that babies as young as four months old display enhanced somatosensory brain activity when a touch is preceded by an object moving towards them. This suggests that even in the first few months of life, babies can sense their surroundings and understand how their bodies interact with space.
Researchers discovered a malaria protein, PfAP2-P, that plays a key regulatory role in immune evasion and parasite development. This protein acts as an activator of proteins required for the parasite to exit infected red blood cells and invade new ones.
Brazilian researchers found that Zika-infected mice with microcephaly have lower Ndel1 enzyme activity, which plays a key role in neuron differentiation and migration. The study suggests that Ndel1 may be a biomarker for early diagnosis of microcephaly and offers hope for treatment options.
A UCLA-led team has identified RBFox1, an RNA splicing regulator, as a key player in promoting human stem cell-derived heart muscle cell maturation. This finding offers a deeper understanding of heart muscle cell development and hints at future therapeutic applications for regenerative therapies.
University of Liverpool researchers develop a new material that captures coronavirus particles with minimal impact on breathability, increasing efficiency by approximately 93%. The new material has the potential to be used in various applications, including face masks and air filters.
A study found that Spanish-speaking Latino preschoolers were more generous than their English-speaking peers, while English-speaking children chose competitive options. This suggests that children from collectivist cultures prioritize group well-being over individualism even at a young age.
A team of researchers has discovered that the worm C. elegans uses a unique system to regulate its development, with a quartet of molecules working in concert to control gene expression. This process shares similarities with human circadian clocks, and understanding how it operates could provide insights into developmental biology.
A recent study found that pain in the lower limbs of children and adolescents may indicate the presence or risk of migraines. The study included 100 children with mothers who experienced migraines, with growing pains occurring in half of them. After five years of follow-up, headaches occurred in 76% of participants with growing pains.