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When danger is about, mice look to their friends

Researchers found that mice moved closer to a familiar companion when hearing a warning signal, but not with a stranger. This suggests a brain circuit that links social memory to threat response, with the hippocampus acting as a gatekeeper for familiar interactions.

SourceVirginia Tech·JournalNeuropsychopharmacology·TypeExperimental study·DateSep 22, 2026

Oxytocin selectively boosts trust

A new study confirms that oxytocin selectively increases trusting behavior in men with a low disposition to trust, regardless of their trust scores. The hormone's effect persists even after controlling for personality traits, suggesting that oxytocin may intensify the expectation of cooperation and reduce fear of being cheated.

SourceUniversity of Zurich·JournalProceedings of the National Academy of Sciences·TypeRandomized controlled/clinical trial·DateAug 12, 2026

Oxytocin linked to group competition

A new study by researchers at UZH's Institute of Evolutionary Medicine found that oxytocin levels increase during football matches, particularly against familiar rivals. The study suggests that oxytocin plays a key role in team dynamics and group boundaries, potentially promoting cooperation and cohesion.

SourceUniversity of Zurich·JournalProceedings of the Royal Society B Biological Sciences·TypeObservational study·DateMay 6, 2026

Scientists discover a key mechanism regulating how oxytocin is released in the mouse brain

Researchers have identified a molecular mechanism that regulates the slow and sustained release of oxytocin within the brain, which is essential for modulating social interactions. This finding provides new insights into how hormonal signaling is regulated in the brain and opens avenues for research into neuropsychiatric disorders.

SourceUniversidad Miguel Hernandez de Elche·JournalCommunications Biology·TypeExperimental study·DateFeb 19, 2026

Synthetic oxytocin may prevent anxiety caused by social stress, according to a study in an animal model

A study published in Progress in Neurobiology found that synthetic oxytocin carbetocin can prevent anxiety-related behaviors in laboratory rats exposed to social stress. The researchers observed that carbetocin had a preventive effect on anxiety without having direct anxiolytic effects.

Hair oxytocin levels may reflect mother–child emotional bond, BGU study finds

A new study suggests that hair oxytocin levels can reflect the emotional connection between parents and young children. Higher maternal oxytocin levels were associated with higher-quality emotional interaction between mother and child, while children's hair oxytocin levels were higher than those of their mothers.

SourceBen-Gurion University of the Negev·JournalEuropean Neuropsychopharmacology·TypeExperimental study·DateFeb 4, 2026

Using rare sugars to address alcoholism

A new protocol models alcoholism in mice and shows that stimulating the FGF21-oxytocin-dopamine system with rare sugars can reduce alcohol consumption. The researchers believe that this system may play a role in regulating subconscious information processing, leading to effective dietary therapy for reducing over-drinking.

SourceKyoto University·JournalProceedings of the National Academy of Sciences·TypeExperimental study·DateJan 12, 2026

Marriage, emotional support may protect against obesity through brain-gut connection, study finds

A new study published in Gut Microbes reveals that married individuals with higher perceived emotional support have a lower body mass index and fewer food addiction behaviors. The study found that oxytocin pathways linking the brain, gut microbiome, and eating behaviors play a crucial role in shaping obesity risk.

New EndoCompass Research Roadmap calls for coordinated investment to tackle Europe’s hormone health challenge

The European Society of Endocrinology has released the EndoCompass Research Roadmap, a major new initiative to align research efforts and improve funding strategies for hormone-related health challenges. The roadmap identifies specific research needs across eight endocrine specialties and five cross-cutting areas.

SourceEuropean Society of Endocrinology·TypeCommentary/editorial·DateOct 17, 2025

MDMA psychiatric applications synthesized: Comprehensive review examines PTSD treatment and emerging therapeutic indications

The review synthesizes clinical evidence on MDMA-assisted psychotherapy for posttraumatic stress disorder (PTSD), autism spectrum disorder, eating disorders, and existential distress. It identifies consistent patterns across diverse clinical applications and highlights the therapeutic potential of MDMA, including its oxytocin-mediated ...

SourceGenomic Press·JournalPsychedelics·TypeLiterature review·DateOct 14, 2025

Rats are more motivated to help their friends

Researchers found that rats are more likely to aid distressed peers if they have previous positive social interactions with them. Helper rats showed increased activity in brain regions associated with empathy and motivation compared to less helpful rats. Oxytocin signaling may play a role in motivating rats to care for others.

SourceSociety for Neuroscience·JournalJNeurosci·DateApr 28, 2025

Mice exhibit altruistic rescue behavior driven by oxytocin

Researchers have found that mice can instinctively exhibit rescue-like behavior toward anesthetized conspecifics without prior training or external rewards. Oxytocin neurons in the paraventricular nucleus are activated when detecting distress signals, releasing OXT and coordinating emotional and motor responses.

SourceChinese Academy of Sciences Headquarters·JournalProceedings of the National Academy of Sciences·TypeMeta-analysis·DateApr 23, 2025

A familiar face at childbirth makes a difference

A Dartmouth-led study reveals that pregnant individuals with no emotional support during childbirth experience higher levels of perceived stress, comparable to a C-section delivery. The research highlights the importance of access to emotional support in reducing stress and improving maternal and child outcomes.

SourceDartmouth College·JournalEvolution Medicine and Public Health·TypeSurvey·DateFeb 3, 2025

New oral drug to calm abdominal pain

Researchers have developed a new class of oral painkillers to suppress chronic abdominal pain. The painkillers are based on the peptide hormone oxytocin, which drives childbirth contractions, and work in the colon without crossing into the bloodstream.

SourceUniversity of Queensland·JournalAngewandte Chemie·TypeExperimental study·DateNov 18, 2024

Research connecting gut bacteria and oxytocin provides a new mechanism for microbiome-promoted health benefits

Researchers have discovered that the gut bacteria Lactobacillus reuteri produces oxytocin, a hormone involved in social behavior and wound healing, in human intestinal tissue. This finding provides a novel explanation for how the microbiome affects distant organs and suggests potential treatments for autism spectrum disorders.

SourceBaylor College of Medicine·JournalGut Microbes·TypeExperimental study·DateNov 2, 2023

Weighted blanket increases melatonin

A new study from Uppsala University found that using a weighted blanket at bedtime increases melatonin production by about 30 percent. The researchers also discovered that the weight of the blanket (12% of participant's body weight) reduced stress system activity, but had no effect on oxytocin and cortisol levels.

SourceUppsala University·JournalJournal of Sleep Research·TypeExperimental study·DateOct 3, 2022

‘Love hormone’ revealed to have heart healing properties

Researchers discover that oxytocin stimulates stem cells to migrate and develop into cardiomyocytes in zebrafish and human cell cultures. This could lead to the regeneration of damaged hearts after a heart attack. The study found that oxytocin also activates EpiPCs, which can replenish lost cardiomyocytes.

SourceFrontiers·JournalFrontiers in Cell and Developmental Biology·TypeExperimental study·DateSep 30, 2022

Shedding light on the happy hormone

A novel fluorescent sensor has been developed to visualize the release of oxytocin, also known as the 'happy hormone', in living animals. The sensor, called MTRIA OT, allows for real-time measurement of extracellular oxytocin dynamics in the brain, revealing variability in OT levels dependent on behavioral and physical conditions.

SourceOsaka University·JournalNature Methods·TypeImaging analysis·DateSep 22, 2022

Dogs cry more when reunited with their owners

A study published in Current Biology found that dogs shed tears associated with positive emotions, such as reuniting with their owners, suggesting a stronger bond between humans and dogs. Oxytocin may play a role in this emotional response, with researchers also noting that people tend to respond more positively to teary-eyed dog faces.

SourceCell Press·JournalCurrent Biology·TypeExperimental study·DateAug 22, 2022

Exploring factors that may underlie how domestic cats can live in groups

A new study explores relationships between domestic cats' hormone levels, gut microbiomes, and social behaviors in cohabitating groups. The research found that low testosterone and cortisol concentrations enabled cats to share space, while high oxytocin levels were associated with less affiliative behavior.

SourcePLOS·JournalPLOS ONE·TypeObservational study·DateJul 27, 2022

Oxytocin spreads cooperation in social networks

Administering oxytocin to central social network members spreads cooperation via increased punishment of uncooperative behavior, Li et al. found in a new study published in JNeurosci. Cooperation can conflict with individual goals, but oxytocin may have evolved humans' need for group living.

SourceSociety for Neuroscience·JournalJNeurosci·TypeExperimental study·DateJun 27, 2022